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List of works by Irene Lorand-Metze

A Novel Assay for the Identification of NOTCH1 PEST Domain Mutations in Chronic Lymphocytic Leukemia

scientific article published on 15 December 2016

A high angiopoietin-2/angiopoietin-1 ratio is associated with a high risk of septic shock in patients with febrile neutropenia

scientific article

A possible role of the P53 gene deletion as a prognostic factor in multiple myeloma.

scientific article published on 29 May 2003

A randomised, prospective comparison of allogeneic bone marrow and peripheral blood progenitor cell transplantation in the treatment of haematological malignancies

scientific article published on 01 December 1998

Acute Megakaryoblastic Leukemia: Importance of Bone Marrow Biopsy in Diagnosis

scientific article published on 01 January 1991

Acute leukemias in Piauí: comparison with features observed in other regions of Brazil.

scientific article published on 7 March 2003

Adherence to tyrosine kinase inhibitor therapy for chronic myeloid leukemia: a Brazilian single-center cohort.

scientific article

Adult T-cell leukemia (ATL) with an unusual immunophenotype and a high cellular proliferation rate.

scientific article published in August 1996

Age related decrease of AgNOR activity in acute and chronic lymphocytic leukaemias.

scientific article published on February 1999

Alterations in cell maturity and serum survival factors may modulate neutrophil numbers in sickle cell disease

scientific article published on 13 October 2011

Analysis of Vgamma/Jbeta trans-rearrangements in paediatric patients undergoing chemotherapy

scientific article published on 01 June 2001

BCR-ABL1 Transcript Levels at 3 and 6 Months Are Better for Identifying Chronic Myeloid Leukemia Patients with Poor Outcome in Response to Second-Line Second-Generation Tyrosine Kinase Inhibitors after Imatinib Failure: A Report from a Single Instit

scientific article published in January 2015

Bone marrow lymphoid aggregates in myelodysplastic syndromes: incidence, immunomorphological characteristics and correlation with clinical features and survival

scientific article published on 01 June 2002

Bone marrow morphology at diagnosis as a prognostic parameter in Philadelphia-positive chronic myelogenous leukaemia (CML)

scientific article published on 01 January 1989

Bone marrow morphology in patients with neutropenia due to chronic exposure to organic solvents (benzene): early lesions

scientific article published on 01 February 1994

Brazilian Group of Flow Cytometry (GBCFLUX) panels for acute leukemias--Response to Matos

scientific article published on 20 January 2015

Brazilian experience using high dose sequential chemotherapy followed by autologous hematopoietic stem cell transplantation for malignant lymphomas.

scientific article

Brazilian experience using high-dose sequential chemotherapy followed by autologous hematopoietic stem cell transplantation for relapsed or refractory Hodgkin lymphoma.

scientific article published in December 2009

Cardiovascular Risk and Cardiovascular Events in Patients With Chronic Myeloid Leukemia Treated With Tyrosine Kinase Inhibitors

scientific article published on 20 December 2018

Causes of incidental neutropenia in adulthood.

scientific article published on 29 June 2006

Changes in AgNOR configurations during the evolution and treatment of chronic lymphocytic leukemia

scientific article published on 01 November 1999

Changes of nucleolar organizer regions in granulopoietic precursors during the course of chronic myeloid leukemia

scientific article published on 01 December 1995

Characteristics of the phenotypic abnormalities of bone marrow cells in childhood myelodysplastic syndromes and juvenile myelomonocytic leukemia.

scientific article published on 17 October 2016

Chronic lymphocytic leukemia in Brazil: A retrospective analysis of 1903 cases.

scientific article

Chronic myeloid leukemia in a homosexual HIV-seropositive man

scientific article published on 01 September 1990

Circulating progenitor and mature endothelial cells in deep vein thrombosis

scientific article published on 14 October 2013

Clinical outcomes of patients with acute myeloid leukemia: evaluation of genetic and molecular findings in a real-life setting.

scientific article

Computerized texture analysis of atypical immature myeloid precursors in patients with myelodysplastic syndromes: an entity between blasts and promyelocytes.

scientific article

Concomitant essential thrombocythemia with JAK2 V617F mutation in a patient with chronic myeloid leukemia with major molecular response with imatinib and long-term follow-up.

scientific article published on 26 May 2016

Constitutive JunB expression, associated with the JAK2 V617F mutation, stimulates proliferation of the erythroid lineage.

scientific article

Conventional chemotherapy for acute myeloid leukemia: a Brazilian experience

scientific article published on 01 November 2000

Cutaneous adverse reaction to 2-chlorodeoxyadenosine with histological flame figures in patients with chronic lymphocytic leukaemia.

scientific article

Detection of hematopoietic maturation abnormalities by flow cytometry in myelodysplastic syndromes and its utility for the differential diagnosis with non-clonal disorders

scientific article published on 05 June 2006

Diagnosis and treatment of chronic lymphocytic leukemia: recommendations from the Brazilian Group of Chronic Lymphocytic Leukemia.

scientific article published on 20 August 2016

Diagnosis of Scott syndrome in patient with bleeding disorder of unknown cause.

scientific article published in January 2012

Diagnosis of chronic lymphoproliferative disorders by flow cytometry using four-color combinations for immunophenotyping: A proposal of the Brazilian Group of Flow Cytometry (GBCFLUX).

scientific article published on 30 June 2016

Downregulation of IRS2 in myelodysplastic syndrome: A possible role in impaired hematopoietic cell differentiation ⬇️

scientific article published on March 31, 2012

Early total white blood cell recovery is a predictor of low number of apheresis and good CD34(+) cell yield

scientific article published on 01 October 2000

Effect of cytokines and chemokines on sickle neutrophil adhesion to fibronectin.

scientific article published on January 2005

Erratum to "Diagnosis and treatment of chronic lymphocytic leukemia: Recommendations from the Brazilian Group of Chronic Lymphocytic Leukemia" [Rev Bras Hematol Hemoter. 2016;38(4):346-357].

scientific article published on January 2017

Evaluation of reticulated platelets in patients with sickle cell diseases

scientific article published on 22 May 2007

Ex vivo expansion of CD56+ NK and NKT-like lymphocytes from peripheral blood mononuclear cells of patients with ovarian neoplasia

scientific article published on 01 September 2011

Expression profiles of phosphatidylinositol phosphate kinase genes during normal human in vitro erythropoiesis

scientific article published on 12 November 2012

Expressions of the VLA-4, LFA-1 and Mac-1 integrins in eosinophil migration in a case of chronic eosinophilic leukaemia

scientific article published on 07 September 2006

Factors influencing survival in myelodysplastic syndromes in a Brazilian population: comparison of FAB and WHO classifications

article

Familial systemic mastocytosis with germline KIT K509I mutation is sensitive to treatment with imatinib, dasatinib and PKC412.

scientific article published in August 2014

Flow cytometric analysis of the expression of Fas/Fasl in bone marrow CD34+ cells in myelodysplastic syndromes: relation to disease progression.

scientific article published in February 2004

Flow cytometry diagnosis in myelodysplastic syndrome: Current practice in Latin America and comparison with other regions of the world

scientific article published on 24 January 2019

Fractal characteristics of May-Grünwald-Giemsa stained chromatin are independent prognostic factors for survival in multiple myeloma.

scientific article

Frontline therapy with early intensification and autologous stem cell transplantation versus conventional chemotherapy in unselected high-risk, aggressive non-Hodgkin's lymphoma patients: a prospective randomized GEMOH report.

scientific article published in January 2006

GSTM1 and codon 72 P53 polymorphism in multiple myeloma

scientific article published on 25 July 2007

Goodness-of-fit of the fractal dimension as a prognostic factor.

scientific article published in January 2009

Guidelines on myelodysplastic syndromes: Associação Brasileira de Hematologia, Hemoterapia e Terapia Celular

scientific article published on 02 July 2018

Hematopoietic progenitor cells (HPC) and immature reticulocytes evaluations in mobilization process: new parameters measured by conventional blood cell counter

scientific article published on 01 January 2006

Hemophagocytic syndrome: pitfalls in its diagnosis

scientific article published on 01 September 1997

Histological and cytological heterogeneity of bone marrow in Philadelphia-positive chronic myelogenous leukaemia at diagnosis

scientific article published on 01 September 1987

IRAK1 expression in bone marrow cells does not impact patient outcomes in myelodysplastic syndromes.

scientific article published on 28 November 2017

IRS2 silencing increases apoptosis and potentiates the effects of ruxolitinib in JAK2V617F-positive myeloproliferative neoplasms.

scientific article published on 9 January 2016

Imbalance between proliferation and in vitro apoptosis rates predicts progression in chronic lymphocytic leukemia

scientific article published on 31 July 2015

Imbalances in serum angiopoietin concentrations are early predictors of septic shock development in patients with post chemotherapy febrile neutropenia

scientific article

Immunophenotypic characteristics of juvenile myelomonocytic leukaemia and their relation with the molecular subgroups of the disease

scientific article published on 23 September 2020

Immunophenotyping in myelodysplastic syndromes can add prognostic information to well-established and new clinical scores

scientific article

Improving the differential diagnosis between myelodysplastic syndromes and reactive peripheral cytopenias by multiparametric flow cytometry: the role of B-cell precursors

scientific article published on 29 April 2015

Influence of BCR-ABL Transcript Type on Outcome in Patients With Chronic-Phase Chronic Myeloid Leukemia Treated With Imatinib.

scientific article

Interpretation of the AgNOR pattern in hematologic cytology

scientific article published on 01 January 1993

Leptin inhibits apoptosis in thymus through a janus kinase-2-independent, insulin receptor substrate-1/phosphatidylinositol-3 kinase-dependent pathway.

scientific article published on 27 July 2006

Lipopolysaccharide treatment reduces rat platelet aggregation independent of intracellular reactive-oxygen species generation

scientific article published on 02 August 2011

Low Ten-eleven-translocation 2 (TET2) transcript level is independent of TET2 mutation in patients with myeloid neoplasms.

scientific article published on 16 March 2016

Low educational level but not low income impairs the achievement of cytogenetic remission in chronic myeloid leukemia patients treated with imatinib in Brazil.

scientific article published on May 2015

Low expression of APAF-1XL in acute myeloid leukemia may be associated with the failure of remission induction therapy.

scientific article published in July 2008

Lowering the p-value from 0.05 to 0.005 conflicts with the 3R rules - an advocacy for alternatives to hypothesis testing with the p-value approach

scientific article published on 01 January 2018

Lymphoblastic transformation of myelodysplastic syndrome

scientific article published on 01 July 1997

Magnetic resonance imaging of femoral marrow cellularity in hypocellular haemopoietic disorders

scientific article published on 01 February 2001

Microparticles in deep venous thrombosis, antiphospholipid syndrome and Factor V Leiden.

scientific article published in September 2009

Molecular analysis of the retinoblastoma (RB1) gene in acute myeloid leukemia patients

scientific article published on 01 September 1998

Molecular characteristics and chromatin texture features in acute promyelocytic leukemia ⬇️

scientific article published on June 28, 2012

Molecular identification of the HLA-DRB1-DQB1 for diagnosis and follow-up of acute leukemias.

scientific article

Monocyte phenotypic aberrancies are an unfavorable prognostic factor in patients with myelodysplastic syndromes and low IPSS-R scores

scientific article published on 14 September 2016

Morphology of bone marrow in systemic lupus erythematosus

scientific article

Multiple lymphoid nodules in bone marrow biopsy in immunocompetent patient with cytomegalovirus infection: an immunohistochemical analysis.

scientific article published on July 2001

Mutations in the p53 gene in acute myeloid leukemia patients correlate with poor prognosis

scientific article published on 01 February 2002

Myelodysplastic syndrome with synchronous gastric cancer: when the symptoms suggest something else

scientific article published on 17 July 2014

Nitric oxide regulates human eosinophil adhesion mechanisms in vitro by changing integrin expression and activity on the eosinophil cell surface

scientific article

No contribution of GSTM1 and GSTT1 null genotypes to the risk of neutropenia due to benzene exposure in Southeastern Brazil

scientific article

Normal variation of bone marrow B-cell precursors according to age - reference ranges for studies in myelodysplastic syndromes in Brazil.

scientific article

Nucleolus organizer regions (AgNORs) and total tumor mass are independent prognostic parameters for treatment-free period in chronic lymphocytic leukemia

scientific article published on 01 September 2000

Pancytopenia in untreated patients with Graves' disease

scientific article published on 01 April 2006

Part 2: Myelodysplastic syndromes - classification systems

scientific article published on 02 July 2018

Participation of leptin in the determination of the macrophage phenotype: an additional role in adipocyte and macrophage crosstalk ⬇️

scientific article published on May 25, 2013

Polymorphisms of VEGF, GSTM1 and GSTT1 genes in multiple myeloma risk

scientific article published on 02 August 2011

Polymorphisms of glutathione S-transferase Mu 1, glutathione S-transferase theta 1 and glutathione S-transferase Pi 1 genes in Hodgkin's lymphoma susceptibility and progression.

scientific article published in June 2009

Polymorphisms of methylenetetrahydrofolate reductase (MTHFR), methionine synthase (MTR), methionine synthase reductase (MTRR), and thymidylate synthase (TYMS) in multiple myeloma risk

scientific article published on 25 July 2007

Presence of B-cell precursors in bone marrow is a favorable independent prognostic factor for overall survival in patients with myelodysplastic syndromes

scientific article published on 14 October 2016

Primary myelofibrosis: risk stratification by IPSS identifies patients with poor clinical outcome.

scientific article published on January 2013

Quantifying loss of CD34+ cells collected by apheresis after processing for freezing and post-thaw

scientific article published on 06 February 2013

Rapid method for isolation of DNA from glass slide smears for PCR

scientific article published on 01 January 1992

Relationship between morphometric analysis of nucleolar organizer regions and cell proliferation in acute leukemias

scientific article published on 01 May 1998

Scoring of PD-L1 positivity: Are we analyzing enough cells?

scientific article published on 27 April 2020

Screening for hotspot mutations in PI3K, JAK2, FLT3 and NPM1 in patients with myelodysplastic syndromes.

scientific article

Sideroblastic anemia following treatment of chronic myeloid leukemia with busulfan

scientific article published on 01 January 2000

Somatic mutations of calreticulin in a Brazilian cohort of patients with myeloproliferative neoplasms

scientific article published on 15 April 2015

Spontaneous apoptosis in chronic lymphocytic leukemia and its relationship to clinical and cell kinetic parameters

scientific article published on 01 December 2001

Stathmin 1 inhibition amplifies ruxolitinib-induced apoptosis in JAK2V617F cells

scientific article published on 24 August 2015

Stathmin 1 is involved in the highly proliferative phenotype of high-risk myelodysplastic syndromes and acute leukemia cells

scientific article

Ten-eleven-translocation 2 (TET2) is downregulated in myelodysplastic syndromes

scientific article published on 01 October 2014

Thalidomide plus dexamethasone as a maintenance therapy after autologous hematopoietic stem cell transplantation improves progression-free survival in multiple myeloma

scientific article published on 23 June 2012

The Brazilian Pediatric Myelodysplastic Cooperative Group strategies: are they relevant to improve educational approach and correct diagnosis?

scientific article published on July 2002

The World Health Organisation classification of myelodysplastic syndromes contains prognostically relevant information beyond the prognostic scores IPSS-R or WPSS

scientific article published on 04 January 2017

The impact of maternal HIV infection on cord blood lymphocyte subsets and cytokine profile in exposed non-infected newborns.

scientific article

The impact of several phenotypic features at diagnosis on survival of patients with myelodysplastic syndromes

scientific article published on 01 January 2010

The influence of storage and leukocyte depletion on the antigen densities of FY1, FY2, MNS3 and MNS4 measured by flow cytometry.

scientific article published on 11 March 2008

The prognostic relevance of apoptosis-related proteins in classical Hodgkin's lymphomas

scientific article published on 01 March 2003

The prognostic value of maturation-associated phenotypic abnormalities in myelodysplastic syndromes.

scientific article

The rare t(6;8) (q27;p11) translocation in a case of chronic myeloid neoplasm mimicking polycythemia vera

scientific article published on 01 September 2008

The utility of multiparametric flow cytometry for the detection of minimal residual disease in acute lymphoblastic leukemia.

scientific article published on January 2012

Time-course of sFlt-1 and VEGF-A release in neutropenic patients with sepsis and septic shock: a prospective study

scientific article

Treatment of prolymphocytic leukemia with cladribine

scientific article published on 01 February 1998

Treatment with dasatinib or nilotinib in chronic myeloid leukemia patients who failed to respond to two previously administered tyrosine kinase inhibitors--a single center experience

scientific article published in August 2015

Umbilical cord blood CD34(+) stem cells and other mononuclear cell subtypes processed up to 96 h from collection and stored at room temperature maintain a satisfactory functionality for cell therapy

scientific article published on 21 October 2014

Vanishing bile duct syndrome in Hodgkin's disease: case report.

scientific article

Variation of bone marrow CD34+ cell subsets in myelodysplastic syndromes according to who types.

scientific article published in January 2009

Viability of umbilical cord blood mononuclear cell subsets until 96 hours after collection

scientific article published on 16 January 2013

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