List of works - Gediminas Cepinskas

Adaptive cytoprotection in the small intestine: role of mucus

scientific article published on 01 May 1993

Albumin leak across human pulmonary microvascular vs. umbilical vein endothelial cells under septic conditions.

scientific article published on 22 December 2005

Anoxia/reoxygenation-induced tolerance with respect to polymorphonuclear leukocyte adhesion to cultured endothelial cells. A nuclear factor-kappaB-mediated phenomenon.

scientific article

Anti-alpha4beta1 integrin antibody induces receptor internalization and does not impair the function of circulating neutrophilic leukocytes.

scientific article published on 7 March 2010

Anti-inflammatory effects of carbon monoxide-releasing molecule on trinitrobenzene sulfonic acid-induced colitis in mice

scientific article published on 19 January 2014

Aspirin-induced, neutrophil-mediated injury to vascular endothelium

scientific article published on 01 June 1995

CORM-401 reduces ischemia reperfusion injury in an ex vivo renal porcine model of the donation after cardiac death

scientific article published on 19 April 2018

CXCL1/CXCL8 (GROα/IL-8) in human diabetic ketoacidosis plasma facilitates leukocyte recruitment to cerebrovascular endothelium in vitro

article

Carbon Monoxide-Releasing Molecule-401 Suppresses Polymorphonuclear Leukocyte Migratory Potential by Modulating F-Actin Dynamics.

scientific article published on 17 March 2017

Carbon liberated from CO-releasing molecules attenuates leukocyte infiltration in the small intestine of thermally injured mice.

scientific article published on December 2007

Carbon monoxide liberated from carbon monoxide-releasing molecule CORM-2 attenuates inflammation in the liver of septic mice

scientific article published on 08 November 2007

Carbon monoxide releasing molecule-3 improves myocardial function in mice with sepsis by inhibiting NLRP3 inflammasome activation in cardiac fibroblasts

scientific article published on 6 February 2017

Carbon monoxide releasing molecules inhibit cell death resulting from renal transplantation related stress.

scientific article published on 14 December 2012

Carbon monoxide-releasing molecule 3 inhibits myeloperoxidase (MPO) and protects against MPO-induced vascular endothelial cell activation/dysfunction.

scientific article published on 26 February 2014

Carbon monoxide-releasing molecule CORM-3 suppresses vascular endothelial cell SOD-1/SOD-2 activity while up-regulating the cell surface levels of SOD-3 in a heparin-dependent manner

scientific article published on 24 August 2010

Carbon monoxide-releasing molecule, CORM-3, modulates alveolar macrophage M1/M2 phenotype in vitro.

scientific article published on 3 July 2017

Carbon monoxide-releasing molecule-3 (CORM-3) offers protection in an in vitro model of compartment syndrome

scientific article published on 19 July 2019

Carbon monoxide-releasing molecules protect against ischemia-reperfusion injury during kidney transplantation.

scientific article

Cardiac myocytes activated by septic plasma promote neutrophil transendothelial migration: role of platelet-activating factor and the chemokines LIX and KC.

scientific article published on 26 February 2004

Cardiac myocytes exposed to anoxia-reoxygenation promote neutrophil transendothelial migration

scientific article published on 01 July 2001

Compartment syndrome causes systemic inflammation in a rat.

scientific article published in August 2016

Contribution of inflammation to cellular injury in compartment syndrome in an experimental rodent model.

scientific article published in April 2015

Delayed preconditioning in cardiac myocytes with respect to development of a proinflammatory phenotype: role of SOD and NOS

scientific article published on 01 October 2003

Detrimental effects of prolonged warm renal ischaemia-reperfusion injury are abrogated by supplemental hydrogen sulphide: an analysis using real-time intravital microscopy and polymerase chain reaction

scientific article published on 09 October 2012

Dextran sulfate sodium-induced acute colonic inflammation in angiotensin II type 1a receptor deficient mice.

scientific article

Diabetic ketoacidosis elicits systemic inflammation associated with cerebrovascular endothelial cell dysfunction.

scientific article

Dynamic regulation of plasma matrix metalloproteinases in human diabetic ketoacidosis.

scientific article published on 22 October 2015

Early mobilization in the critical care unit: A review of adult and pediatric literature.

scientific article published on 08 April 2015

Elevated Leukocyte Azurophilic Enzymes in Human Diabetic Ketoacidosis Plasma Degrade Cerebrovascular Endothelial Junctional Proteins.

scientific article published on 11 April 2016

Endothelial E- and P-selectin expression in iNOS- deficient mice exposed to polymicrobial sepsis.

scientific article

Endotoxin promotes adhesion of human erythrocytes to human vascular endothelial cells under conditions of flow

scientific article published on 01 June 2000

Endotoxin-induced adhesion of human red blood cells to vascular endothelium does not depend on the presence of leukocytes but is modified by different flow pattern.

scientific article published in March 1998

Epidermal growth factor attenuates jejunal mucosal injury induced by oleic acid: role of mucus

scientific article published on 01 December 1994

Extract of Helicobacter pylori induces neutrophils to injure endothelial cells and contains antielastase activity

scientific article published on 01 January 1996

Helicobacter pylori-induced microvascular protein leakage in rats: role of neutrophils, mast cells, and platelets

scientific article published on 01 July 1994

Hindlimb ischemia/reperfusion-induced remote injury to the small intestine: role of inducible nitric-oxide synthase-derived nitric oxide.

scientific article published on 6 March 2009

Human neutrophil-pulmonary microvascular endothelial cell interactions in vitro: differential effects of nitric oxide vs. peroxynitrite.

scientific article published on 14 June 2008

Human severe sepsis cytokine mixture increases β2-integrin-dependent polymorphonuclear leukocyte adhesion to cerebral microvascular endothelial cells in vitro

scientific article published on 7 April 2015

Inducible NO synthase (iNOS) in human neutrophils but not pulmonary microvascular endothelial cells (PMVEC) mediates septic protein leak in vitro.

scientific article

Inflammatory response in microvascular endothelium in sepsis: role of oxidants.

scientific article published on May 2008

Interaction between reactive oxygen metabolites and nitric oxide in oxidant tolerance.

scientific article

LPS pretreatment ameliorates peritonitis-induced myocardial inflammation and dysfunction: role of myocytes

scientific article published on 01 September 1999

LPS tolerance in human endothelial cells: reduced PMN adhesion, E-selectin expression, and NF-kappaB mobilization

scientific article published on 01 March 2000

Lung-derived mediators induce cytokine production in downstream organs via an NF-κB-dependent mechanism.

scientific article

Mechanisms and consequences of acquired brain injury during development.

scientific article published on 10 April 2012

Mediators released from LPS-challenged lungs induce inflammatory responses in liver vascular endothelial cells and neutrophilic leukocytes.

scientific article published on 8 October 2009

Metabolomics Profiling of Critically Ill Coronavirus Disease 2019 Patients: Identification of Diagnostic and Prognostic Biomarkers

scientific article published on 21 October 2020

Molecular mechanism of inhibition of early pulmonary injury and inflammatory response by exogenous carbon monoxide: experiment with mice

scientific article published in November 2007

Neutrophil-endothelial cell interactions during the development of tolerance to ischaemia/reperfusion in isolated cells.

scientific article

Neutrophils induce sequential focal changes in endothelial adherens junction components: role of elastase.

scientific article

Nitric oxide attenuates but superoxide enhances iNOS expression in endotoxin- and IFNgamma-stimulated skeletal muscle endothelial cells

scientific article published on 01 December 2001

Nitric oxide synthase activities in white blood cells of septic patients.

scientific article published in January 1999

Omega 3-lipid peroxides injure CaCo-2 cells: relationship to the development of reduced glutathione antioxidant systems.

scientific article published in July 1994

PAF-induced elastase-dependent neutrophil transendothelial migration is associated with the mobilization of elastase to the neutrophil surface and localization to the migrating front.

scientific article published on June 1999

Peritonitis induces rat cardiac myocytes to promote polymorphonuclear leukocyte emigration and activate endothelial cells: effect of lipopolysaccharide pretreatment

scientific article published on 01 September 2001

Polyamines attenuate jejunal mucosal injury induced by oleic acid.

scientific article published in August 1992

Pretreatment of human cerebrovascular endothelial cells with CO-releasing molecule-3 interferes with JNK/AP-1 signaling and suppresses LPS-induced proadhesive phenotype

scientific article

Regional differences in constitutive and induced ICAM-1 expression in vivo

scientific article published on 01 December 1995

Regulation of intestinal nuclear factor-kappaB activity and E-selectin expression during sepsis: a role for peroxynitrite

scientific article published on 01 January 2003

Remote inflammatory response in liver is dependent on the segmental level of spinal cord injury.

scientific article published in May 2012

Simulated diabetic ketoacidosis therapy in vitro elicits brain cell swelling via sodium-hydrogen exchange and anion transport

scientific article

Systemic Administration of Carbon Monoxide-Releasing Molecule-3 Protects the Skeletal Muscle in Porcine Model of Compartment Syndrome

scientific article published on 30 January 2018

Systemic application of carbon monoxide-releasing molecule 3 protects skeletal muscle from ischemia-reperfusion injury

scientific article published on 16 February 2017

The Effect of Tidal Volume on Systemic Inflammation in Acid-Induced Lung Injury ⬇️

scientific article published on February 9, 2011

The plasma proteome differentiates the multisystem inflammatory syndrome in children (MIS-C) from children with SARS-CoV-2 negative sepsis

scientific article published in 2024

The severity of microvascular dysfunction due to compartment syndrome is diminished by the systemic application of CO-releasing molecule-3

scientific article published on 01 November 2014

Transendothelial neutrophil migration. Role of neutrophil-derived proteases and relationship to transendothelial protein movement

scientific article published on 01 October 1997

Translational research in pediatrics II: blood collection, processing, shipping, and storage.

scientific article published on 18 March 2013

Traumatic injury elicits JNK-mediated human astrocyte retraction in vitro.

scientific article

Tumor necrosis factor-alpha-induced cytokine-induced neutrophil chemoattractant-1 (CINC-1) production by rat gastric epithelial cells: role of reactive oxygen species and nuclear factor-kappaB.

scientific article published on 27 January 2004

List of works by Gediminas Cepinskas

Adaptive cytoprotection in the small intestine: role of mucus

Albumin leak across human pulmonary microvascular vs. umbilical vein endothelial cells under septic conditions.

Anoxia/reoxygenation-induced tolerance with respect to polymorphonuclear leukocyte adhesion to cultured endothelial cells. A nuclear factor-kappaB-mediated phenomenon.

Anti-alpha4beta1 integrin antibody induces receptor internalization and does not impair the function of circulating neutrophilic leukocytes.

Anti-inflammatory effects of carbon monoxide-releasing molecule on trinitrobenzene sulfonic acid-induced colitis in mice

Aspirin-induced, neutrophil-mediated injury to vascular endothelium

CORM-401 reduces ischemia reperfusion injury in an ex vivo renal porcine model of the donation after cardiac death

CXCL1/CXCL8 (GROα/IL-8) in human diabetic ketoacidosis plasma facilitates leukocyte recruitment to cerebrovascular endothelium in vitro

Carbon Monoxide-Releasing Molecule-401 Suppresses Polymorphonuclear Leukocyte Migratory Potential by Modulating F-Actin Dynamics.

Carbon liberated from CO-releasing molecules attenuates leukocyte infiltration in the small intestine of thermally injured mice.

Carbon monoxide liberated from carbon monoxide-releasing molecule CORM-2 attenuates inflammation in the liver of septic mice

Carbon monoxide releasing molecule-3 improves myocardial function in mice with sepsis by inhibiting NLRP3 inflammasome activation in cardiac fibroblasts

Carbon monoxide releasing molecules inhibit cell death resulting from renal transplantation related stress.

Carbon monoxide-releasing molecule 3 inhibits myeloperoxidase (MPO) and protects against MPO-induced vascular endothelial cell activation/dysfunction.

Carbon monoxide-releasing molecule CORM-3 suppresses vascular endothelial cell SOD-1/SOD-2 activity while up-regulating the cell surface levels of SOD-3 in a heparin-dependent manner

Carbon monoxide-releasing molecule, CORM-3, modulates alveolar macrophage M1/M2 phenotype in vitro.

Carbon monoxide-releasing molecule-3 (CORM-3) offers protection in an in vitro model of compartment syndrome

Carbon monoxide-releasing molecules protect against ischemia-reperfusion injury during kidney transplantation.

Cardiac myocytes activated by septic plasma promote neutrophil transendothelial migration: role of platelet-activating factor and the chemokines LIX and KC.

Cardiac myocytes exposed to anoxia-reoxygenation promote neutrophil transendothelial migration

Compartment syndrome causes systemic inflammation in a rat.

Contribution of inflammation to cellular injury in compartment syndrome in an experimental rodent model.

Delayed preconditioning in cardiac myocytes with respect to development of a proinflammatory phenotype: role of SOD and NOS

Detrimental effects of prolonged warm renal ischaemia-reperfusion injury are abrogated by supplemental hydrogen sulphide: an analysis using real-time intravital microscopy and polymerase chain reaction

Dextran sulfate sodium-induced acute colonic inflammation in angiotensin II type 1a receptor deficient mice.

Diabetic ketoacidosis elicits systemic inflammation associated with cerebrovascular endothelial cell dysfunction.

Dynamic regulation of plasma matrix metalloproteinases in human diabetic ketoacidosis.

Early mobilization in the critical care unit: A review of adult and pediatric literature.

Elevated Leukocyte Azurophilic Enzymes in Human Diabetic Ketoacidosis Plasma Degrade Cerebrovascular Endothelial Junctional Proteins.

Endothelial E- and P-selectin expression in iNOS- deficient mice exposed to polymicrobial sepsis.

Endotoxin promotes adhesion of human erythrocytes to human vascular endothelial cells under conditions of flow

Endotoxin-induced adhesion of human red blood cells to vascular endothelium does not depend on the presence of leukocytes but is modified by different flow pattern.

Epidermal growth factor attenuates jejunal mucosal injury induced by oleic acid: role of mucus

Extract of Helicobacter pylori induces neutrophils to injure endothelial cells and contains antielastase activity

Helicobacter pylori-induced microvascular protein leakage in rats: role of neutrophils, mast cells, and platelets

Hindlimb ischemia/reperfusion-induced remote injury to the small intestine: role of inducible nitric-oxide synthase-derived nitric oxide.

Human neutrophil-pulmonary microvascular endothelial cell interactions in vitro: differential effects of nitric oxide vs. peroxynitrite.

Human severe sepsis cytokine mixture increases β2-integrin-dependent polymorphonuclear leukocyte adhesion to cerebral microvascular endothelial cells in vitro

Inducible NO synthase (iNOS) in human neutrophils but not pulmonary microvascular endothelial cells (PMVEC) mediates septic protein leak in vitro.

Inflammatory response in microvascular endothelium in sepsis: role of oxidants.

Interaction between reactive oxygen metabolites and nitric oxide in oxidant tolerance.

LPS pretreatment ameliorates peritonitis-induced myocardial inflammation and dysfunction: role of myocytes

LPS tolerance in human endothelial cells: reduced PMN adhesion, E-selectin expression, and NF-kappaB mobilization

Lung-derived mediators induce cytokine production in downstream organs via an NF-κB-dependent mechanism.

Mechanisms and consequences of acquired brain injury during development.

Mediators released from LPS-challenged lungs induce inflammatory responses in liver vascular endothelial cells and neutrophilic leukocytes.

Metabolomics Profiling of Critically Ill Coronavirus Disease 2019 Patients: Identification of Diagnostic and Prognostic Biomarkers

Molecular mechanism of inhibition of early pulmonary injury and inflammatory response by exogenous carbon monoxide: experiment with mice

Neutrophil-endothelial cell interactions during the development of tolerance to ischaemia/reperfusion in isolated cells.

Neutrophils induce sequential focal changes in endothelial adherens junction components: role of elastase.

Nitric oxide attenuates but superoxide enhances iNOS expression in endotoxin- and IFNgamma-stimulated skeletal muscle endothelial cells

Nitric oxide synthase activities in white blood cells of septic patients.

Omega 3-lipid peroxides injure CaCo-2 cells: relationship to the development of reduced glutathione antioxidant systems.

PAF-induced elastase-dependent neutrophil transendothelial migration is associated with the mobilization of elastase to the neutrophil surface and localization to the migrating front.

Peritonitis induces rat cardiac myocytes to promote polymorphonuclear leukocyte emigration and activate endothelial cells: effect of lipopolysaccharide pretreatment

Polyamines attenuate jejunal mucosal injury induced by oleic acid.

Pretreatment of human cerebrovascular endothelial cells with CO-releasing molecule-3 interferes with JNK/AP-1 signaling and suppresses LPS-induced proadhesive phenotype

Regional differences in constitutive and induced ICAM-1 expression in vivo

Regulation of intestinal nuclear factor-kappaB activity and E-selectin expression during sepsis: a role for peroxynitrite

Remote inflammatory response in liver is dependent on the segmental level of spinal cord injury.

Simulated diabetic ketoacidosis therapy in vitro elicits brain cell swelling via sodium-hydrogen exchange and anion transport

Systemic Administration of Carbon Monoxide-Releasing Molecule-3 Protects the Skeletal Muscle in Porcine Model of Compartment Syndrome

Systemic application of carbon monoxide-releasing molecule 3 protects skeletal muscle from ischemia-reperfusion injury

The Effect of Tidal Volume on Systemic Inflammation in Acid-Induced Lung Injury ⬇️

The plasma proteome differentiates the multisystem inflammatory syndrome in children (MIS-C) from children with SARS-CoV-2 negative sepsis

The severity of microvascular dysfunction due to compartment syndrome is diminished by the systemic application of CO-releasing molecule-3

Transendothelial neutrophil migration. Role of neutrophil-derived proteases and relationship to transendothelial protein movement

Translational research in pediatrics II: blood collection, processing, shipping, and storage.

Traumatic injury elicits JNK-mediated human astrocyte retraction in vitro.

Tumor necrosis factor-alpha-induced cytokine-induced neutrophil chemoattractant-1 (CINC-1) production by rat gastric epithelial cells: role of reactive oxygen species and nuclear factor-kappaB.