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List of works by Maria Amparo Alfonso Rancaño

13-Desmethyl spirolide-c and 13,19-didesmethyl spirolide-c trans-epithelial permeabilities: human intestinal permeability modelling

scientific article published on 12 June 2011

A rapid microplate fluorescence method to detect yessotoxins based on their capacity to activate phosphodiesterases

scientific article published in March 2004

Azaspiracid-1, a potent, nonapoptotic new phycotoxin with several cell targets.

scientific article

Azaspiracid-4 inhibits Ca2+ entry by stored operated channels in human T lymphocytes.

scientific article published on 20 April 2005

Azaspiracids modulate intracellular pH levels in human lymphocytes.

scientific article

Benefit of 13-desmethyl spirolide C treatment in triple transgenic mouse model of Alzheimer disease: beta-amyloid and neuronal markers improvement.

scientific article published in March 2013

Bioengineered protein phosphatase 2A: update on need

scientific article

Bromotryptamine and Bromotyramine Derivatives from the Tropical Southwestern Pacific Sponge Narrabeena nigra

scientific article published on 30 May 2019

C-kit mutations and PKC crosstalks: PKC translocates to nucleous only in cells HMC⁵⁶⁰,⁸¹⁶.

scientific article published on September 2011

Calcium pools, calcium entry, and cell growth.

scientific article published on April 1996

Changes in rat mast cell responses in sodium-free media. Lack of demonstrable sodium channel activity

scientific article published on 01 May 1991

Characterization and activity determination of the human protein phosphatase 2A catalytic subunit α expressed in insect larvae.

scientific article

Characterization of F-actin depolymerization as a major toxic event induced by pectenotoxin-6 in neuroblastoma cells

scientific article published in June 2002

Characterization of the Na+/Ca2+ exchanger on rat mast cells. Evidence for a functional role on the regulation of the cellular response

scientific article published on 01 January 1999

Characterization of the dinophysistoxin-2 acute oral toxicity in mice to define the Toxicity Equivalency Factor.

scientific article

Combined Effect of Caspase-Dependent and Caspase-Independent Apoptosis in the Anticancer Activity of Gold Complexes with Phosphine and Benzimidazole Derivatives

scientific article published on 24 December 2020

Comparative analysis of pre- and post-column oxidation methods for detection of paralytic shellfish toxins

scientific article published on 11 May 2010

Comparative study of the stability of saxitoxin and neosaxitoxin in acidic solutions and lyophilized samples.

scientific article

Crosstalk between cytosolic pH and intracellular calcium in human lymphocytes: effect of 4-aminopyridin, ammoniun chloride and ionomycin

scientific article published on 01 August 2000

Cytotoxic effect of palytoxin on mussel.

scientific article published on 3 March 2010

Decrease of marine toxin content in bivalves by industrial processes.

scientific article published on 5 August 2009

Detection of anatoxin-a and three analogs in Anabaena spp. cultures: new fluorescence polarization assay and toxin profile by LC-MS/MS.

scientific article published on 24 January 2014

Determination of phosphodiesterase activity in rat mast cells using the fluorescent cAMP analogue anthraniloyl cAMP

scientific article published on 01 July 1995

Different role of cAMP pathway on the human mast cells HMC-1(560) and HMC-1(560,816) activation.

scientific article published on May 2014

Dimethylsphingosine increases cytosolic calcium and intracellular pH in human T lymphocytes.

scientific article published on February 2003

Effect of lyophilization on the stability of gonyautoxins obtained from contaminated mussels.

scientific article published in July 1994

Effect of purification, theophylline and sodium fluoride on histamine release produced by antineoplastic drugs on rat mast cells. A distinctive mechanism of action for carboplatin

scientific article published on 01 August 1992

Effect of signal transduction pathways on the action of thapsigargin on rat mast cells. Crosstalks between cellular signalling and cytosolic pH

scientific article published on 01 May 1994

Effects of Azaspiracids 2 and 3 on intracellular cAMP, [Ca2+], and pH.

scientific article

Functional compartments in rat mast cells for cAMP and calcium on histamine release

scientific article published on 01 May 2000

Gracilin-Derivatives as Lead Compounds for Anti-inflammatory Effects

scientific article published on 15 November 2019

High Serum Cyclophilin C levels as a risk factor marker for Coronary Artery Disease

scientific article published on 22 July 2019

Hypertonicity-induced intracellular pH changes in rat mast cells

scientific article published on 01 September 2000

In vitro and in vivo evaluation of paralytic shellfish poisoning toxin potency and the influence of the pH of extraction.

scientific article

Influence of protein kinase C, cAMP and phosphatase activity on histamine release produced by compound 48/80 and sodium fluoride on rat mast cells

scientific article published on September 1, 1992

Influence of the tyrosine kinase inhibitors STI571 (Glivec), lavendustin A and genistein on human mast cell line (HMC-1(560)) activation.

scientific article

Kinetic analysis of the interaction between yessotoxin and analogues and immobilized phosphodiesterases using a resonant mirror optical biosensor

scientific article published in July 2005

Lack of specific saxitoxin binding to rat mast cells.

scientific article

Maitotoxin-induced calcium entry in human lymphocytes: modulation by yessotoxin, Ca(2+) channel blockers and kinases.

scientific article

Mitigation of ROS insults by Streptomyces secondary metabolites in primary cortical neurons ⬇️

scientific article

Modulation of calcium entry and glutamate release in cultured cerebellar granule cells by palytoxin.

scientific article published in June 2006

Multi-detection method for five common microalgal toxins based on the use of microspheres coupled to a flow-cytometry system.

scientific article

Natural Approaches for Neurological Disorders-The Neuroprotective Potential of Codium tomentosum

scientific article published on 23 November 2020

New gastropod vectors and tetrodotoxin potential expansion in temperate waters of the Atlantic Ocean.

scientific article

New invertebrate vectors for PST, spirolides and okadaic acid in the North Atlantic.

scientific article published on 5 June 2013

Non-immunological release of histamine from rat mast cells elicited by antineoplastic agents

scientific article published on 01 January 1992

Nonimmunological release of histamine from rat mast cells elicited by antineoplastic agents: effect of drug combinations

scientific article published on 01 January 1992

Oral toxicity of okadaic acid in mice: study of lethality, organ damage, distribution and effects on detoxifying gene expression.

scientific article

Ouabain-induced enhancement of rat mast cells response. Modulation by protein phosphorylation and intracellular pH.

scientific article published in July 2001

Palytoxin detection and quantification using the fluorescence polarization technique

scientific article published on 25 February 2012

Palytoxins and cytoskeleton: An overview.

scientific article published on 07 October 2010

Pharmacokinetic and toxicological data of spirolides after oral and intraperitoneal administration.

scientific article

Quantification of yessotoxin using the fluorescence polarization technique and study of the adequate extraction procedure

scientific article published in September 2005

Recovery of Ca2+ pools and growth in Ca2+ pool-depleted cells is mediated by specific epoxyeicosatrienoic acids derived from arachidonic acid

scientific article published on 01 November 1997

Resonant mirror biosensor detection method based on yessotoxin-phosphodiesterase interactions.

scientific article published in December 2004

Role of AKAP 149-PKA-PDE4A complex in cell survival and cell differentiation processes

scientific article published on 9 May 2014

Role of yessotoxin in calcium and cAMP‐crosstalks in primary and K‐562 human lymphocytes: The effect is mediated by Anchor kinase a mitochondrial proteins ⬇️

scientific article published on December 1, 2012

STI571 (Glivec) affects histamine release and intracellular pH after alkalinisation in HMC-1560, 816.

scientific article

Simplified immunosuppressive and neuroprotective agents based on gracilin A

scientific article published on 22 March 2019

Sodium, PMA and calcium play an important role on intracellular pH modulation in rat mast cells

scientific article published on 01 January 1998

Spongionella secondary metabolites protect mitochondrial function in cortical neurons against oxidative stress

scientific article published on 27 January 2014

Study of the activation mechanism of human GRF(1-29)NH2 on rat mast cell histamine release

scientific article published on 01 February 1995

Study of the interaction between different phosphodiesterases and yessotoxin using a resonant mirror biosensor

scientific article published in June 2006

Study of the neuronal effects of ouabain and palytoxin and their binding to Na,K-ATPases using an optical biosensor

scientific article published on 10 May 2007

Synthesis and antiallergic activity of pyridothienopyrimidines

scientific article published on 01 October 1998

The antineoplastic drug vinorelbine activates non-immunological histamine release from rat mast cells

scientific article published on 01 April 1997

The methyl ester of okadaic acid is more potent than okadaic acid in disrupting the actin cytoskeleton and metabolism of primary cultured hepatocytes

scientific article

Yessotoxin, a novel phycotoxin, activates phosphodiesterase activity. Effect of yessotoxin on cAMP levels in human lymphocytes.

scientific article

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