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List of works by Osborne F.X. Almeida

Activated PPARγ Abrogates Misprocessing of Amyloid Precursor Protein, Tau Missorting and Synaptotoxicity

scientific article published on 12 June 2019

Acute and chronic stress differentially regulate cyclin-dependent kinase 5 in mouse brain: implications to glucocorticoid actions and major depression

scientific article published on 9 June 2015

Age-related qualitative shift in emotional behaviour: paradoxical findings after re-exposure of rats in the elevated-plus maze.

scientific article published on 12 April 2005

Altered motivation masks appetitive learning potential of obese mice.

scientific article

Androgen receptor-mediated regulation of adrenocortical activity in the sand rat, Psammomys obesus

scientific article published on 2 September 2014

Antidepressant responsiveness in adulthood is permanently impaired after neonatal destruction of the neurogenic pool.

scientific article published on 3 January 2017

Astrocytic GluN2A and GluN2B Oppose the Synaptotoxic Effects of Amyloid-β1-40 in Hippocampal Cells.

scientific article

Blunted leptin sensitivity during hedonic overeating can be reinstated by activating galanin 2 receptors (Gal2R) in the lateral hypothalamus

scientific article published on 31 July 2019

Chronic Stress and Glucocorticoids: From Neuronal Plasticity to Neurodegeneration

scientific article

Chronic melatonin treatment and the hypothalamo‐pituitary‐adrenal axis in the rat: Attenuation of the secretory response to stress and effects on hypothalamic neuropeptide content and release ⬇️

scientific article published on December 1, 1997

Chronic melatonin treatment counteracts glucocorticoid-induced dysregulation of the hypothalamic-pituitary-adrenal axis in the rat.

scientific article published in March 1998

Citalopram-mediated anxiolysis and differing neurobiological responses in both sexes of a genetic model of depression.

scientific article published on 4 August 2011

Corticosteroid status influences the volume of the rat cingulate cortex - a magnetic resonance imaging study.

scientific article published on 4 March 2005

Corticosteroids: way upstream

scientific article

Corticotropin releasing hormone effects on peptidergic neurons of the hypothalamus.

scientific article

Day and night: diurnal phase influences the response to chronic mild stress

scientific article published on 14 March 2014

Differential Regulation of N-Methyl-D-Aspartate Receptor Subunits is an Early Event in the Actions of Soluble Amyloid-β(1-40) Oligomers on Hippocampal Neurons

scientific article published on 22 January 2016

Differential regulation and function of 5'-untranslated GR-exon 1 transcripts.

scientific article

Direct targeting of hippocampal neurons for apoptosis by glucocorticoids is reversible by mineralocorticoid receptor activation.

scientific article published in August 2005

Disassembly of shank and homer synaptic clusters is driven by soluble beta-amyloid(1-40) through divergent NMDAR-dependent signalling pathways

scientific journal article

Disconnection and reconnection: the morphological basis of (mal)adaptation to stress.

scientific article published on 21 September 2012

Dissociation of the morphological correlates of stress-induced anxiety and fear.

scientific article published on 10 March 2008

Dynamic DNA methylation programs persistent adverse effects of early-life stress

scientific article

Early-life stress reduces DNA methylation of the Pomc gene in male mice.

scientific article

European Neuroendocrine Association--ninth meeting. 3-7 September 1999, Odense, Denmark.

scientific article published in December 1999

Female hippocampus vulnerability to environmental stress, a precipitating factor in Tau aggregation pathology

scientific article

Gender differences in ethanol preference and ingestion in rats. The role of the gonadal steroid environment ⬇️

scientific article published on June 15, 1998

Gender differences in the regulation of 3 alpha-hydroxysteroid dehydrogenase in rat brain and sensitivity to neurosteroid-mediated stress protection.

scientific article published in January 2003

Glucocorticoids and neuro- and behavioural development.

scientific article published on 12 December 2008

Glucocorticoids trigger Alzheimer disease-like pathobiochemistry in rat neuronal cells expressing human tau.

scientific article

Hormones and adult neurogenesis in mammals

scientific article published on 01 March 2007

Immunoglobulin G Fc receptor deficiency prevents Alzheimer-like pathology and cognitive impairment in mice.

scientific article published in September 2012

Induction of a hyperanxious state by antenatal dexamethasone: a case for less detrimental natural corticosteroids.

scientific article

Insidious adrenocortical insufficiency underlies neuroendocrine dysregulation in TIF-2 deficient mice.

scientific article published on 29 November 2006

Ionotropic and metabotropic glutamate receptor mediation of glucocorticoid-induced apoptosis in hippocampal cells and the neuroprotective role of synaptic N-methyl-D-aspartate receptors.

scientific article published in January 2003

Ligand and subfield specificity of corticoid-induced neuronal loss in the rat hippocampal formation.

scientific article

Local Somatodendritic Translation and Hyperphosphorylation of Tau Protein Triggered by AMPA and NMDA Receptor Stimulation.

scientific article published on 17 May 2017

Mapping cellular gains and losses in the postnatal dentate gyrus: implications for psychiatric disorders.

scientific article

Mechanisms of initiation and reversal of drug-seeking behavior induced by prenatal exposure to glucocorticoids.

scientific article

Mismatch between anxiety status and morphometric parameters in the amygdala and bed nucleus of the stria terminalis.

scientific article published on 10 August 2006

Multiple factors influencing the in vitro release of [Met5]-enkephalin from rat hypothalamic slices.

scientific article published in February 1989

Neurodevelopment milestone abnormalities in rats exposed to stress in early life.

scientific article published on 22 June 2007

Neuropathology of stress

scientific article published on 08 December 2013

Neuroplasticity-related correlates of environmental enrichment combined with physical activity differ between the sexes

scientific article published on 27 November 2018

Neuropsychology of Neuroendocrine Dysregulation after Traumatic Brain Injury

scientific article

Ontogeny of gender-specific responsiveness to stress and glucocorticoids in the rat and its determination by the neonatal gonadal steroid environment.

scientific article published in August 1999

Optimized Analysis of DNA Methylation and Gene Expression from Small, Anatomically-defined Areas of the Brain ⬇️

scientific article published on July 12, 2012

Paradoxical LH and prolactin responses to naloxone after chronic treatment with morphine

scientific article published on 01 February 1986

Pavlovian conditioning and cross-sensitization studies raise challenges to the hypothesis that overeating is an addictive behavior.

scientific article

Programming effects of antenatal dexamethasone in the developing mesolimbic pathways.

scientific article published on January 2007

Reorganization of the morphology of hippocampal neurites and synapses after stress-induced damage correlates with behavioral improvement.

scientific article

Restoring Serotonergic Homeostasis in the Lateral Hypothalamus Rescues Sleep Disturbances Induced by Early-Life Obesity.

scientific article

Reward components of feeding behavior are preserved during mouse aging

scientific article

Role of melatonin and circadian rhythms in seasonal reproduction in rams

scientific article published on 01 January 1981

Selective inhibitors of the FK506-binding protein 51 by induced fit

scientific article

Sexual differentiation of the luteinizing hormone response of neonatal rats to the narcotic antagonist naloxone: critical role of estrogen receptors

scientific article published on 01 December 1988

Steroid action in neural and neuroendrocine systems

scientific article published on 01 October 1999

Stress and the Neuroendocrinology of Anxiety Disorders ⬇️

scientific article published on January 1, 2010

Stress- and corticosteroid-induced modulation of the locomotor response to morphine in rats.

scientific article published in August 1999

Stress-induced anhedonia is associated with hypertrophy of medium spiny neurons of the nucleus accumbens.

scientific article

Tau Deletion Prevents Stress-Induced Dendritic Atrophy in Prefrontal Cortex: Role of Synaptic Mitochondria

scientific article published on 12 April 2016

Tau Depletion in APP Transgenic Mice Attenuates Task-Related Hyperactivation of the Hippocampus and Differentially Influences Locomotor Activity and Spatial Memory.

scientific article published in March 2018

Tau protein is essential for stress-induced brain pathology

scientific article

The Arctic/Swedish APP mutation alters the impact of chronic stress on cognition in mice

scientific article published on 13 July 2019

The amyloidogenic potential and behavioral correlates of stress.

scientific article published on 2 October 2007

The future is now: early life events preset adult behaviour.

scientific article published on 13 July 2013

The mood-improving actions of antidepressants do not depend on neurogenesis but are associated with neuronal remodeling.

scientific article

The nucleus reuniens: a key node in the neurocircuitry of stress and depression

scientific article published on 11 April 2017

The prototypic mineralocorticoid receptor agonist aldosterone influences neurogenesis in the dentate gyrus of the adrenalectomized rat.

scientific article

The stressed prefrontal cortex. Left? Right!

scientific article

Toxic tau oligomer formation blocked by capping of cysteine residues with 1,2-dihydroxybenzene groups.

scientific article

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