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List of works by Luciana Leite

A Bivalent Recombinant BCG Expressing the S1 Subunit of the Pertussis Toxin Induces a Polyfunctional CD4 T Cell Immune Response

scientific article published on 28 February 2019

A Combination of Recombinant Mycobacterium bovis BCG Strains Expressing Pneumococcal Proteins Induces Cellular and Humoral Immune Responses and Protects against Pneumococcal Colonization and Sepsis

scientific article

A Single Dose of a DNA Vaccine Encoding Apa Coencapsulated with 6,6′-Trehalose Dimycolate in Microspheres Confers Long-Term Protection against Tuberculosis in Mycobacterium bovis BCG-Primed Mice ⬇️

scientific article published on 05 June 2013

A protein chimera including PspA in fusion with PotD is protective against invasive pneumococcal infection and reduces nasopharyngeal colonization in mice.

scientific article published on 14 August 2017

A quantitative view of the transcriptome of Schistosoma mansoni adult-worms using SAGE

scientific article

Addressing racial inequalities in a pandemic: data limitations and a call for critical analyses

scientific article published on 15 September 2020

Adjuvant activity of Mycobacterium bovis BCG expressing CRM197 on the immune response induced by BCG expressing tetanus toxin fragment C.

scientific article published in January 2004

Advocacy, partnership and political commitment for TB vaccine research

scientific article published on 16 June 2016

Analysis of serum cross-reactivity and cross-protection elicited by immunization with DNA vaccines against Streptococcus pneumoniae expressing PspA fragments from different clades.

scientific article

Carbon-centered free radical formation during the metabolism of hydrazine derivatives by neutrophils

scientific article published on 01 May 1993

Characterization of phosphodiesterase-5 as a surface protein in the tegument of Schistosoma mansoni.

scientific article

Characterization of the snake venoms from seven Brazilian species of Bothrops by FPLC anion-exchange chromatography

scientific article published on 01 July 1992

Combined effects of lactoferrin and lysozyme on Streptococcus pneumoniae killing

scientific article published on 19 August 2015

Conjugation of PspA4Pro with Capsular Streptococcus pneumoniae Polysaccharide Serotype 14 Does Not Reduce the Induction of Cross-Reactive Antibodies

scientific article published on 21 June 2017

Conjugation of polysaccharide 6B from Streptococcus pneumoniae with pneumococcal surface protein A: PspA conformation and its effect on the immune response

scientific article published on 3 April 2013

Construction of an unmarked recombinant BCG expressing a pertussis antigen by auxotrophic complementation: protection against Bordetella pertussis challenge in neonates.

scientific article published on 25 September 2009

Contribution of hydrazines-derived alkyl radicals to cytotoxicity and transformation induced in normal c-myc-overexpressing mouse fibroblasts ⬇️

scientific article published on January 1, 1998

Current status and perspectives on protein-based pneumococcal vaccines ⬇️

scientific article published on July 29, 2013

DNA strand scission by the carbon radical derived from 2-phenyl-ethylhydrazine metabolism.

scientific article

DNA vaccines expressing pneumococcal surface protein A (PspA) elicit protection levels comparable to recombinant protein

scientific article published on 01 April 2006

Developing Countries Vaccine Manufacturers Network (DCVMN): Engaging to step up for vaccine discovery and access. Meeting Report 2012 ⬇️

scientific article published on May 15, 2013

Developing Countries Vaccine Manufacturers Network: doing good by making high-quality vaccines affordable for all.

scientific article published on April 2013

Development of a whole cell pneumococcal vaccine: BPL inactivation, cGMP production, and stability.

scientific article published on 14 December 2013

Enhancement of Th1 lung immunity induced by recombinant Mycobacterium bovis Bacillus Calmette-Guerin attenuates airway allergic disease

scientific article published on 05 October 2009

Expression and characterization of cholera toxin B-pneumococcal surface adhesin A fusion protein in Escherichia coli: ability of CTB-PsaA to induce humoral immune response in mice

scientific article published on 01 August 2004

Expression of Streptococcus pneumoniae antigens, PsaA (pneumococcal surface antigen A) and PspA (pneumococcal surface protein A) by Lactobacillus casei.

scientific article published in October 2003

First report of a dead giant squid (Architeuthis dux) from an operating seismic vessel

article by Luciana Leite et al published 1 July 2016 in Marine biodiversity records

Fusion proteins containing family 1 and family 2 PspA fragments elicit protection against Streptococcus pneumoniae that correlates with antibody-mediated enhancement of complement deposition.

scientific article

GMP-grade pneumococcal whole-cell vaccine injected subcutaneously protects mice from nasopharyngeal colonization and fatal aspiration-sepsis ⬇️

scientific article published on September 19, 2010

Genetic diversity of PspA types among nasopharyngeal isolates collected during an ongoing surveillance study of children in Brazil

scientific article

HFE Variants and the Expression of Iron-Related Proteins in Breast Cancer-Associated Lymphocytes and Macrophages

scientific article published on 27 December 2016

Hemoglobin-mediated oxidation of the carcinogen 1,2-dimethylhydrazine to methyl radicals

scientific article published on 01 November 1988

Humoral immune response of a pneumococcal conjugate vaccine: Capsular polysaccharide serotype 14—Lysine modified PspA

article

IL-17A and complement contribute to killing of pneumococci following immunization with a pneumococcal whole cell vaccine.

scientific article published on February 2017

Immunization of mice with single PspA fragments induces antibodies capable of mediating complement deposition on different pneumococcal strains and cross-protection.

scientific article

Immunization with tegument nucleotidases associated with a subcurative praziquantel treatment reduces worm burden following Schistosoma mansoni challenge.

scientific article published on 2 April 2013

Induction of boosted immune response in mice by leptospiral surface proteins expressed in fusion with DnaK.

scientific article

Induction of neutralizing antibodies against diphtheria toxin by priming with recombinant Mycobacterium bovis BCG expressing CRM(197), a mutant diphtheria toxin.

scientific article published on February 2001

Induction of systemic and mucosal immune response and decrease in Streptococcus pneumoniae colonization by nasal inoculation of mice with recombinant lactic acid bacteria expressing pneumococcal surface antigen A.

scientific article published on 18 January 2006

Mycobacterial codon optimization of the gene encoding the Sm14 antigen of Schistosoma mansoni in recombinant Mycobacterium bovis Bacille Calmette-Guérin enhances protein expression but not protection against cercarial challenge in mice.

scientific article

Nasal immunization of mice with Lactobacillus casei expressing the Pneumococcal Surface Protein A: induction of antibodies, complement deposition and partial protection against Streptococcus pneumoniae challenge

scientific article published on 20 January 2008

Neonatal immunization with a single dose of recombinant BCG expressing subunit S1 from pertussis toxin induces complete protection against Bordetella pertussis intracerebral challenge

scientific article published on 20 November 2007

New Recombinant Mycobacterium bovis BCG Expression Vectors: Improving Genetic Control over Mycobacterial Promoters

scientific article published on 5 February 2016

On the three-finger protein domain fold and CD59-like proteins in Schistosoma mansoni.

scientific article

Optimization and scale-up production of Zika virus ΔNS1 in Escherichia coli: application of Response Surface Methodology

scientific article published on 31 December 2019

Optimization of Expression and Purification of Schistosoma mansoni Antigens in Fusion with Rhizavidin

scientific article published on 24 June 2021

Optimized immune response elicited by a DNA vaccine expressing pneumococcal surface protein a is characterized by a balanced immunoglobulin G1 (IgG1)/IgG2a ratio and proinflammatory cytokine production

scientific article

Optimizing expression of Streptococcus pneumoniae surface protein a, PspA: serocross-reactivity within families of antisera induced against clades 1 and 3

scientific article published on 01 October 2007

Platelet activating factor, an endogenous mediator of inflammation, induces phenotypic transformation of rat embryo cells.

scientific article published in July 1993

Process intensification for production of Streptococcus pneumoniae whole-cell vaccine

scientific article published on 18 February 2020

Proliferation of mouse fibroblasts induced by 1,2-dimethylhydrazine auto-oxidation: role of iron and free radicals.

scientific article published on May 1997

Protection induced by pneumococcal surface protein A (PspA) is enhanced by conjugation to a Streptococcus pneumoniae capsular polysaccharide

scientific article published on 09 April 2008

Protective efficacy of PspA (pneumococcal surface protein A)-based DNA vaccines: contribution of both humoral and cellular immune responses.

scientific article published in June 2003

PsaA (pneumococcal surface adhesin A) and PspA (pneumococcal surface protein A) DNA vaccines induce humoral and cellular immune responses against Streptococcus pneumoniae

scientific article published on 01 December 2001

Rational selection of broadly cross-reactive family 2 PspA molecules for inclusion in chimeric pneumococcal vaccines.

scientific article published on 7 June 2017

Recognition of pneumococcal isolates by antisera raised against PspA fragments from different clades

scientific article published on 01 March 2008

Recombinant BCG Expressing LTAK63 Adjuvant induces Superior Protection against Mycobacterium tuberculosis

scientific article published on 18 May 2017

Recombinant BCG expressing a PspA-PdT fusion protein protects mice against pneumococcal lethal challenge in a prime-boost strategy.

scientific article published on 24 February 2017

Recombinant BCG expressing the LTAK63 adjuvant induces increased early and long-term immune responses against Mycobacteria

scientific article published on 31 October 2019

Recombinant vaccines and the development of new vaccine strategies.

scientific article published on 06 September 2012

Rheumatic hand's clinical, functional and imagiological correlations following metacarpophalangeal joint silicone arthroplasty.

scientific article published on 30 March 2017

Role of Streptococcus pneumoniae Proteins in Evasion of Complement-Mediated Immunity.

scientific article published on 20 February 2017

Saci-1, -2, and -3 and Perere, four novel retrotransposons with high transcriptional activities from the human parasite Schistosoma mansoni

scientific article

Schistosoma mansoni Annexin 2: molecular characterization and immunolocalization

scientific article

Schistosoma mansoni Venom Allergen Like Proteins Present Differential Allergic Responses in a Murine Model of Airway Inflammation ⬇️

scientific article published on February 7, 2012

Schistosoma mansoni venom allergen-like protein 18 (SmVAL18) is a plasminogen-binding protein secreted during the early stages of mammalian-host infection.

scientific article published on 22 February 2018

Schistosoma mansoni venom allergen-like protein 4 (SmVAL4) is a novel lipid-binding SCP/TAPS protein that lacks the prototypical CAP motifs. Corrigendum.

scientific article published on 27 March 2015

Schistosoma mansoni: molecular characterization of Alkaline Phosphatase and expression patterns across life cycle stages.

scientific article published on 18 July 2011

Schistosoma mansonivenom allergen-like protein 4 (SmVAL4) is a novel lipid-binding SCP/TAPS protein that lacks the prototypical CAP motifs

scientific article

Schistosome transcriptome: insights and perspectives for functional genomics.

scientific article published on July 2004

Schistosomiasis--a century searching for chemotherapeutic drugs.

scientific article

Screening the Schistosoma mansoni transcriptome for genes differentially expressed in the schistosomulum stage in search for vaccine candidates.

scientific article

Selection of family 1 PspA molecules capable of inducing broad-ranging cross-reactivity by complement deposition and opsonophagocytosis by murine peritoneal cells ⬇️

scientific article published on January 4, 2011

Sm21.6 a novel EF-hand family protein member located on the surface of Schistosoma mansoni adult worm that failed to induce protection against challenge infection but reduced liver pathology.

scientific article published on 14 May 2009

Stage and tissue expression patterns of Schistosoma mansoni venom allergen-like proteins SmVAL 4, 13, 16 and 24.

scientific article

Systemic immunization with rPotD reduces Streptococcus pneumoniae nasopharyngeal colonization in mice

scientific article published on 21 November 2016

The Challenges Imposed by Dengue, Zika, and Chikungunya to Brazil

article

The Schistosome Esophagus Is a 'Hotspot' for Microexon and Lysosomal Hydrolase Gene Expression: Implications for Blood Processing

scientific article published on 7 December 2015

The contribution of 700,000 ORF sequence tags to the definition of the human transcriptome.

scientific article

The long search for a serotype independent pneumococcal vaccine

scientific article published on 23 January 2020

The therapeutic potential of recombinant BCG expressing the antigen S1PT in the intravesical treatment of bladder cancer.

scientific article published on 9 March 2009

Too intelligent for the life sciences in Brazil: how two female researchers fought back

scientific article published on 21 October 2020

Vaccines of the Future: The Role of Inflammation and Adjuvanticity

scientific article

Vitamins as influenza vaccine adjuvant components

scientific article published on 23 July 2016

Whole-genome analysis of Leptospira interrogans to identify potential vaccine candidates against leptospirosis.

scientific article published in March 2005

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