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List of works by Bärbel Friedrich

A DNA region recognized by the nitric oxide-responsive transcriptional activator NorR is conserved in beta- and gamma-proteobacteria

scientific article published on December 2004

A Universal Scaffold for Synthesis of the Fe(CN)2(CO) Moiety of [NiFe] Hydrogenase ⬇️

scientific article published on September 27, 2012

A kinetic and thermodynamic understanding of O2 tolerance in [NiFe]-hydrogenases.

scientific article

A model system for [NiFe] hydrogenase maturation studies: Purification of an active site-containing hydrogenase large subunit without small subunit

scientific article published in August 2005

A proteomic view of the facultatively chemolithoautotrophic lifestyle of Ralstonia eutropha H16.

scientific article published in November 2009

A trimeric supercomplex of the oxygen-tolerant membrane-bound [NiFe]-hydrogenase from Ralstonia eutropha H16.

scientific article published on 29 November 2011

A unique iron-sulfur cluster is crucial for oxygen tolerance of a [NiFe]-hydrogenase

scientific article

Adopt a moratorium on heritable genome editing

scientific article published on 01 March 2019

An improved purification procedure for the soluble [NiFe]-hydrogenase of Ralstonia eutropha: new insights into its (in)stability and spectroscopic properties

scientific article published on 18 January 2006

Analyses of Soluble and Membrane Proteomes of Ralstonia eutropha H16 Reveal Major Changes in the Protein Complement in Adaptation to Lithoautotrophy ⬇️

scientific article published on May 11, 2011

Autotrophic production of stable-isotope-labeled arginine in Ralstonia eutropha strain H16.

scientific article published on 31 August 2012

Bias from H2 cleavage to production and coordination changes at the Ni-Fe active site in the NAD+-reducing hydrogenase from Ralstonia eutropha

scientific article published in September 2006

CO synthesized from the central one-carbon pool as source for the iron carbonyl in O2-tolerant [NiFe]-hydrogenase

scientific article published on 05 December 2016

Carbamoylphosphate serves as the source of CN(-), but not of the intrinsic CO in the active site of the regulatory [NiFe]-hydrogenase from Ralstonia eutropha.

scientific article published on 21 June 2007

Chaperones specific for the membrane-bound [NiFe]-hydrogenase interact with the Tat signal peptide of the small subunit precursor in Ralstonia eutropha H16

scientific article published on 10 September 2007

Characterization of the norB gene, encoding nitric oxide reductase, in the nondenitrifying cyanobacterium Synechocystis sp. strain PCC6803.

scientific article published on February 2002

Climate change and infectious diseases--impact of global warming and climate change on infectious diseases: myth or reality?

scientific article published on 14 October 2011

Cofactor composition and function of a H2-sensing regulatory hydrogenase as revealed by Mössbauer and EPR spectroscopy

scientific article

Comparison of the membrane-bound [NiFe] hydrogenases from R. eutropha H16 and D. vulgaris Miyazaki F in the oxidized ready state by pulsed EPR.

scientific article published on 15 January 2010

Complete genome sequence of the type strain Cupriavidus necator N-1.

scientific article

Complete nucleotide sequence of pHG1: a Ralstonia eutropha H16 megaplasmid encoding key enzymes of H(2)-based ithoautotrophy and anaerobiosis

scientific article published on September 2003

Concerted action of two novel auxiliary proteins in assembly of the active site in a membrane-bound [NiFe] hydrogenase

scientific article

Coping with anoxia: a comprehensive proteomic and transcriptomic survey of denitrification

scientific article published on 8 September 2014

Crystallization and preliminary X-ray crystallographic analysis of the [NiFe]-hydrogenase maturation factor HypF1 from Ralstonia eutropha H16

scientific article

Direct Detection of a Hydrogen Ligand in the [NiFe] Center of the Regulatory H2-Sensing Hydrogenase fromRalstoniaeutrophain Its Reduced State by HYSCORE and ENDOR Spectroscopy ⬇️

scientific article published on October 29, 2003

Electricity from low-level H2 in still air--an ultimate test for an oxygen tolerant hydrogenase

scientific article published on 9 November 2006

Electrocatalytic hydrogen oxidation by an enzyme at high carbon monoxide or oxygen levels

scientific article

Electrochemical definitions of O2 sensitivity and oxidative inactivation in hydrogenases

scientific article

Enzymatic oxidation of H2 in atmospheric O2: the electrochemistry of energy generation from trace H2 by aerobic microorganisms

scientific article

Erratum: A unique iron-sulfur cluster is crucial for oxygen tolerance of a [NiFe]-hydrogenase

scientific article published on 17 August 2011

Erratum: A unique iron-sulfur cluster is crucial for oxygen tolerance of a [NiFe]-hydrogenase

scholarly article published in Nature Chemical Biology

Expression of a functional NAD-reducing [NiFe] hydrogenase from the gram-positive Rhodococcus opacus in the gram-negative Ralstonia eutropha

scientific article published on 20 November 2001

Fostering responsible research with genome editing technologies: a European perspective.

scientific article published on 20 July 2017

Functional analysis by site-directed mutagenesis of the NAD(+)-reducing hydrogenase from Ralstonia eutropha.

scientific article

Gas pressure effects on the rates of catalytic H(2) oxidation by hydrogenases

scientific article published on 05 October 2010

Genome sequence of the bioplastic-producing "Knallgas" bacterium Ralstonia eutropha H16

scientific article

H2 conversion in the presence of O2 as performed by the membrane-bound [NiFe]-hydrogenase of Ralstonia eutropha

scientific article published on April 2010

Hydrogen production under aerobic conditions by membrane-bound hydrogenases from Ralstonia species

scientific article published on 29 July 2008

Hydrogen sensing by enzyme-catalyzed electrochemical detection

scientific article

Hydrogen-induced structural changes at the nickel site of the regulatory [NiFe] hydrogenase from Ralstonia eutropha detected by X-ray absorption spectroscopy

scientific article

Impact of alterations near the [NiFe] active site on the function of the H(2) sensor from Ralstonia eutropha

scientific article published on 01 January 2007

Impact of amino acid substitutions near the catalytic site on the spectral properties of an O2-tolerant membrane-bound [NiFe] hydrogenase.

scientific article published in April 2010

Light-driven hydrogen production by a hybrid complex of a [NiFe]-hydrogenase and the cyanobacterial photosystem I

scientific article

Monitoring catalysis of the membrane-bound hydrogenase from Ralstonia eutropha H16 by surface-enhanced IR absorption spectroscopy

scientific article published in January 2009

NiFe hydrogenase active site biosynthesis: identification of Hyp protein complexes in Ralstonia eutropha

scientific article published on October 2004

Novel, oxygen-insensitive group 5 [NiFe]-hydrogenase in Ralstonia eutropha.

scientific article published on 21 June 2013

Oxygen tolerance of the H2-sensing [NiFe] hydrogenase from Ralstonia eutropha H16 is based on limited access of oxygen to the active site.

scientific article

Oxygen-tolerant hydrogenases in hydrogen-based technologies.

scientific article published on 18 February 2011

Photosynthetic Hydrogen Production by a Hybrid Complex of Photosystem I and [NiFe]-Hydrogenase

article

Probing the Origin of the Metabolic Precursor of the CO Ligand in the Catalytic Center of [NiFe] Hydrogenase ⬇️

scientific article published on December 30, 2011

Protein-protein complex formation affects the Ni-Fe and Fe-S centers in the H2-sensing regulatory hydrogenase from Ralstonia eutropha H16.

scientific article published in April 2010

Ralstonia eutropha H16 flagellation changes according to nutrient supply and state of poly(3-hydroxybutyrate) accumulation

scientific article

Reduction of Unusual Iron-Sulfur Clusters in the H2-sensing Regulatory Ni-Fe Hydrogenase from Ralstonia eutropha H16

scientific article published in Journal of Biological Chemistry

Regulatory networks in prokaryotes: variations on a theme

scientific article published in May 2002

Requirements for heterologous production of a complex metalloenzyme: the membrane-bound [NiFe] hydrogenase

scientific article

Reversible [4Fe-3S] cluster morphing in an O(2)-tolerant [NiFe] hydrogenase

scientific article

Role of the HoxZ Subunit in the Electron Transfer Pathway of the Membrane-Bound [NiFe]-Hydrogenase from Ralstonia eutropha Immobilized on Electrodes

scientific article published on 09 August 2011

Rubredoxin-related maturation factor guarantees metal cofactor integrity during aerobic biosynthesis of membrane-bound [NiFe] hydrogenase

scientific article

Selective release and function of one of the two FMN groups in the cytoplasmic NAD+-reducing [NiFe]-hydrogenase from Ralstonia eutropha

scientific article published in February 2004

Spectroscopic insights into the oxygen-tolerant membrane-associated [NiFe] hydrogenase of Ralstonia eutropha H16

scientific article published on 20 March 2009

Structural and oxidation-state changes at its nonstandard Ni-Fe site during activation of the NAD-reducing hydrogenase from Ralstonia eutropha detected by X-ray absorption, EPR, and FTIR spectroscopy

scientific article

Structure, function and biosynthesis of O₂-tolerant hydrogenases.

scientific article published on February 2013

The H(2) sensor of Ralstonia eutropha: biochemical and spectroscopic analysis of mutant proteins modified at a conserved glutamine residue close to the [NiFe] active site

scientific article published on 18 June 2002

The H2-sensing complex of Ralstonia eutropha: interaction between a regulatory [NiFe] hydrogenase and a histidine protein kinase.

scientific article published in March 2004

The auxiliary protein HypX provides oxygen tolerance to the soluble [NiFe]-hydrogenase of ralstonia eutropha H16 by way of a cyanide ligand to nickel

scientific article published on 31 August 2004

The complex structure of polyhydroxybutyrate (PHB) granules: four orthologous and paralogous phasins occur in Ralstonia eutropha

scientific article

The crystal structure of an oxygen-tolerant hydrogenase uncovers a novel iron-sulphur centre

scientific article

The hydrogen-sensing apparatus in Ralstonia eutropha.

scientific article

The maturation factors HoxR and HoxT contribute to oxygen tolerance of membrane-bound [NiFe] hydrogenase in Ralstonia eutropha H16.

scientific article published on 25 March 2011

The role of the active site-coordinating cysteine residues in the maturation of the H2-sensing [NiFe] hydrogenase from Ralstonia eutropha H16.

scientific article published on 31 August 2004

The soluble NAD+-Reducing [NiFe]-hydrogenase from Ralstonia eutropha H16 consists of six subunits and can be specifically activated by NADPH.

scientific article published on May 2005

The soluble [NiFe]-hydrogenase from Ralstonia eutropha contains four cyanides in its active site, one of which is responsible for the insensitivity towards oxygen

scientific article published on 26 May 2004

[NiFe] and [FeS] cofactors in the membrane-bound hydrogenase of Ralstonia eutropha investigated by X-ray absorption spectroscopy: insights into O(2)-tolerant H(2) cleavage.

scientific article published on 10 June 2011

[NiFe]-hydrogenases of Ralstonia eutropha H16: modular enzymes for oxygen-tolerant biological hydrogen oxidation

scientific article (publication date: 2005)

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