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List of works by Ian G. Jennings

A naphthoquinone adsorbent for affinity chromatography of human dihydropteridine reductase

scientific article published on February 1, 1978

Biochemical defect of the hph-1 mouse mutant is a deficiency in GTP-cyclohydrolase activity

scientific article published on 01 February 1988

Biophysical characterization of interactions involving importin-alpha during nuclear import

scientific article

Class II but Not Second Class-Prospects for the Development of Class II PI3K Inhibitors.

scientific article published on 24 September 2014

Comparative studies of four monoclonal antibodies to phenylalanine hydroxylase exhibiting different properties with respect to substrate-dependence, species-specificity and a range of effects on enzyme activity.

scientific article published in December 1981

Development of single and mixed isoform selectivity PI3Kδ inhibitors by targeting Asn836 of PI3Kδ.

scientific article published on 11 August 2016

Discovery and antiplatelet activity of a selective PI3Kβ inhibitor (MIPS-9922).

scientific article

Disrupting the platelet internal membrane via PI3KC2α inhibition impairs thrombosis independently of canonical platelet activation

scientific article published on 01 July 2020

Experimental determination of the phosphorylation state of phenylalanine hydroxylase

scientific article published on January 1990

Genetics of mammalian phenylalanine hydroxylase system. IV. Evidence of phenylalanine hydroxylase in a cultured human hepatoma cell line.

scientific article

Genetics of the mammalian phenylalanine hydroxylase system. Studies of human liver phenylalanine hydroxylase subunit structure and of mutations in phenylketonuria ⬇️

scientific article published on August 1, 1979

Immobilization of tryptophan hydroxylase by immune adsorption: a method to study regulation of catalytic activity

scientific article published on December 1, 1992

Observations indicating the nature of the mutation in phenylketonuria

scientific article published on 01 January 1980

Phosphorylation and activation of tryptophan hydroxylase by exogenous protein kinase A.

scientific article published in February 1996

Phosphorylation regulates copper-responsive trafficking of the Menkes copper transporting P-type ATPase.

scientific article published on 2 July 2009

Potent inhibitors of phosphatidylinositol 3 (PI3) kinase that have antiproliferative activity only when delivered as prodrug forms.

scientific article published on 8 April 2013

Regulation of the renal-specific Na+-K+-2Cl- co-transporter NKCC2 by AMP-activated protein kinase (AMPK).

scientific article

Structural similarities among enzyme pterin binding sites as demonstrated by a monoclonal anti-idiotypic antibody

scientific article published on 01 February 1990

Structure and function of the aromatic amino acid hydroxylases.

scientific article published on October 1995

Structure function studies of the phenylalanine hydroxylase active site and a summary of structural features

scientific article published on 01 January 1993

Structure/function analysis of the domains required for the multimerisation of phenylalanine hydroxylase

scientific article published on 01 February 1998

Synthesis of linear and angular aryl-morpholino-naphth-oxazines, their DNA-PK, PI3K, PDE3A and antiplatelet activity.

scientific article published on 5 October 2016

Synthesis, structure elucidation, DNA-PK and PI3K and anti-cancer activity of 8- and 6-aryl-substituted-1-3-benzoxazines.

scientific article published on 27 January 2016

Thiophene inhibitors of PDE4: crystal structures show a second binding mode at the catalytic domain of PDE4D2

scientific article

Tryptophan hydroxylase is phosphorylated by protein kinase A

scientific article published on 01 August 1995

Turn up the HEAT.

scientific article

Use of naphthoquinone adsorbent for the isolation of human dihydropteridine reductase

scientific article published on 01 January 1987

Vectors for expression and amplification of cDNA in mammalian cells: expression of rat phenylalanine hydroxylase

scientific article published on 01 December 1986

[Detection of phenylalanine hydroxylase protein in human platelets. Immunochemical detection]

scientific article published on 01 April 1990

[Phenylalanine hydroxylase-like antibody in human chorionic villi]

scientific article published on 01 September 1992

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