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List of works by Marc De Maeyer

A consensus tetrapeptide selected by phage display adopts the conformation of a dominant discontinuous epitope of a monoclonal anti-VWF antibody that inhibits the von Willebrand factor-collagen interaction

scientific article

A dominant gain-of-function mutation in universal tyrosine kinase SRC causes thrombocytopenia, myelofibrosis, bleeding, and bone pathologies

scientific article

A structural basis for the unique binding features of the human vitamin D-binding protein

scientific article

An alternate sucrose binding mode in the E203Q Arabidopsis invertase mutant: an X-ray crystallography and docking study

scientific article

An unusual red-edge excitation and time-dependent Stokes shift in the single tryptophan mutant protein DD-carboxypeptidase from Streptomyces: the role of dynamics and tryptophan rotamers

scientific article

Binding of the concave surface of the Sds22 superhelix to the alpha 4/alpha 5/alpha 6-triangle of protein phosphatase-1.

scientific article

Biochemical and structural characterization of TLXI, the Triticum aestivum L. thaumatin-like xylanase inhibitor

scientific article published in June 2009

Biochemical characterization of highly purified leucine-rich repeat kinases 1 and 2 demonstrates formation of homodimers

scientific article

Combined Modeling and Biophysical Characterisation of CO2 Interaction with Class II Hydrophobins: New Insight into the Mechanism Underpinning Primary Gushing

Combined molecular and supramolecular bottom-up nanoengineering for enhanced nonlinear optical response: experiments, modeling, and approaching the fundamental limit

scientific article published in February 2007

Computational Studies of the Active and Inactive Regulatory Domains of Response Regulator PhoP Using Molecular Dynamics Simulations

scientific article

Development of resistance against diketo derivatives of human immunodeficiency virus type 1 by progressive accumulation of integrase mutations

scientific article published on November 2003

Evidence for DNA-binding domain--ligand-binding domain communications in the androgen receptor

scientific article

Experimental indication for the existence of multiple Trp rotamers in von Willebrand Factor A3 domain

scientific article published in November 2004

Expression, purification and preliminary biochemical and structural characterization of the leucine rich repeat namesake domain of leucine rich repeat kinase 2.

scientific article

Five lung nodules, four different pathologic findings: not all lung lesions are the same

scientific article published on 4 July 2016

Genome wide analysis and comparative docking studies of new diaryl furan derivatives against human cyclooxygenase-2, lipoxygenase, thromboxane synthase and prostacyclin synthase enzymes involved in inflammatory pathway

scientific article published on 27 August 2009

HIV-1 integrase variants retarget viral integration and are associated with disease progression in a chronic infection cohort

scientific article published on 12 November 2014

How do rotameric conformations influence the time-resolved fluorescence of tryptophan in proteins? A perspective based on molecular modeling and quantum chemistry

scientific article published on October 2008

Identification of the LEDGF/p75 binding site in HIV-1 integrase

scientific article

Impact on replicative fitness of the G48E substitution in the protease of HIV-1: an in vitro and in silico evaluation

scientific article published in July 2008

In search of second-generation HIV integrase inhibitors: targeting integration beyond strand transfer

scientific article published on October 2009

In vivo neutralization of a C2 domain-specific human anti-Factor VIII inhibitor by an anti-idiotypic antibody

scientific article published on 11 December 2003

Influence of limited proteolysis, detergent treatment and lyophilization on the phenoloxidase activity of Rapana thomasiana hemocyanin.

scientific article published on 6 May 2009

Insight into the mode of action of the LRRK2 Y1699C pathogenic mutant

scientific article

Kinases as targets for Parkinson's disease: from genetics to therapy

scientific article published on September 2011

LEDGINs, non-catalytic site inhibitors of HIV-1 integrase: a patent review (2006 - 2014).

scientific article published on 25 March 2014

LRRK2 kinase activity is dependent on LRRK2 GTP binding capacity but independent of LRRK2 GTP binding

scientific article

Mapping the binding interface between an HIV-1 inhibiting intrabody and the viral protein Rev

scientific article

Mechanism of Nonpolar Model Substances to Inhibit Primary Gushing Induced by Hydrophobin HFBI.

scientific article published on 30 April 2015

Multiple mutations in human immunodeficiency virus-1 integrase confer resistance to the clinical trial drug S-1360.

scientific article published in October 2004

Mutation of the H-bond acceptor S119 in the ADAMTS13 metalloprotease domain reduces secretion and substrate turnover in a patient with congenital thrombotic thrombocytopenic purpura

scientific article

Mutations in human immunodeficiency virus type 1 integrase confer resistance to the naphthyridine L-870,810 and cross-resistance to the clinical trial drug GS-9137.

scientific article

Paratope determination of the antithrombotic antibody 82D6A3 based on the crystal structure of its complex with the von Willebrand factor A3-domain

scientific article published on 28 November 2005

Protein simulations: the absorption spectrum of barnase point mutants

scientific article published on July 2004

Rational design of small molecules that modulate the transcriptional function of the response regulator PhoP.

scientific article

Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication

scientific article

Staphylokinase-Specific Cell-Mediated Immunity in Humans ⬇️

scientific article published on January 1, 2002

Structure based discovery of small molecule suppressors targeting bacterial lysozyme inhibitors

scientific article published on 20 January 2011

Structure/activity relationship of thapsigargin inhibition on the purified Golgi/secretory pathway Ca2+/Mn2+-transport ATPase (SPCA1a).

scientific article published on 6 March 2017

Study of recombinant antibody fragments and PAI-1 complexes combining protein-protein docking and results from site-directed mutagenesis

scientific article published in September 2007

The dead-end elimination method, tryptophan rotamers, and fluorescence lifetimes

scientific article

The dead-end elimination theorem and its use in protein side-chain positioning ⬇️

scientific article published on April 9, 1992

Tryptophan conformations associated with partial unfolding in ribonuclease T1

scientific article published on September 2009

Tryptophan rotamers as evidenced by X-ray, fluorescence lifetimes, and molecular dynamics modeling

scientific article

Tuning the Size and Properties of ClyA Nanopores Assisted by Directed Evolution ⬇️

scientific article published on August 27, 2013

Understanding the role of defective invertases in plants: tobacco Nin88 fails to degrade sucrose

scientific article

Validation of APRI and FIB-4 score in an Antwerp cohort of chronic hepatitis C patients

scientific article published on October 2015

Virus evolution reveals an exclusive role for LEDGF/p75 in chromosomal tethering of HIV.

scientific article

pKa modulation of the acid/base catalyst within GH32 and GH68: a role in substrate/inhibitor specificity?

scientific article

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