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List of works by Barbara Przewłocka

A multi-target approach for pain treatment: dual inhibition of fatty acid amide hydrolase and TRPV1 in a rat model of osteoarthritis

scientific article published in May 2015

Adaptive changes in the proenkephalin and D2 dopamine receptor mRNA expression after chronic cocaine in the nucleus accumbens and striatum of the rat.

scientific article published in December 1995

Agonist-dependent attenuation of mu-opioid receptor-mediated G-protein activation in the dorsal root ganglia of neuropathic rats

scientific article published on 6 March 2010

Alterations in the Activity of Spinal and Thalamic Opioid Systems in a Mice Neuropathic Pain Model

scientific article published on 01 September 2018

Analgesic Properties of Opioid/NK1 Multitarget Ligands with Distinct in Vitro Profiles in Naive and Chronic Constriction Injury Mice.

scientific article published on 12 July 2017

Analgesic and convulsant effects of guanidinoethylmercaptosuccinic acid (GEMSA)--a potent enkephalin convertase inhibitor

scientific article published in November 1986

Analgesic effects of antidepressants alone and after their local co-administration with morphine in a rat model of neuropathic pain

scientific article

Anandamide, Acting via CB2 Receptors, Alleviates LPS-Induced Neuroinflammation in Rat Primary Microglial Cultures

scientific article published on 18 May 2015

Anatomical and functional aspects of mu opioid receptors in epileptic WAG/Rij rats

scientific article published in January 1998

Antagonistic effect of cyproheptadine on neuroleptic-induced catalepsy

scientific article published on January 1, 1975

Antagonists of the kappa-opioid receptor enhance allodynia in rats and mice after sciatic nerve ligation

scientific article

Antidepressants and endogenous opioid peptide systems

scientific article published in February 1985

Attenuation of morphine tolerance by minocycline and pentoxifylline in naive and neuropathic mice

scientific article

Bifunctional Peptide-Based Opioid Agonist-Nociceptin Antagonist Ligands for Dual Treatment of Acute and Neuropathic Pain

scientific article published on April 2016

Bifunctional opioid/nociceptin hybrid KGNOP1 effectively attenuates pain-related behaviour in a rat model of neuropathy

scientific article

Blockade of IL-18 signaling diminished neuropathic pain and enhanced the efficacy of morphine and buprenorphine.

scientific article published on 5 January 2016

Blockade of P2X4 Receptors Inhibits Neuropathic Pain-Related Behavior by Preventing MMP-9 Activation and, Consequently, Pronociceptive Interleukin Release in a Rat Model

scientific article published on 16 February 2017

Blockade of Toll-Like Receptors (TLR2, TLR4) Attenuates Pain and Potentiates Buprenorphine Analgesia in a Rat Neuropathic Pain Model

scientific article

Botulinum neurotoxin type A counteracts neuropathic pain and facilitates functional recovery after peripheral nerve injury in animal models.

scientific article published on 6 September 2010

Brain and peripheral opioid peptides after changes in ingestive behavior

scientific article

Central action of Craviten (M-71)

scientific article published on November 1, 1980

Changes in hippocampal immunoreactive dynorphin and neoendorphin content following intra-amygdalar kainic acid-induced seizures

scientific article

Changes induced by formalin pain in central alpha1-adrenoceptor density are modulated by adenosine receptor agonists

scientific article published on 23 March 2010

Corrigendum to: Formalin-induced pain and μ-opioid receptordensity in brain and spinal cord are modulated by A1 and A2a adenosineagonists in mice

scholarly article published in Brain Research

Cross-tolerance between the different mu-opioid receptor agonists endomorphin-1, endomorphin-2 and morphine at the spinal level in the rat.

scientific article published in December 2002

Dataset of botulinum toxin A influence on interleukins under neuropathy

scientific article

Delta-opioid receptor analgesia is independent of microglial activation in a rat model of neuropathic pain

scientific article

Deprivation of REM sleep in the rat and the opioid peptides beta-endorphin and dynorphin

scientific article

Different behavioral responses of rats to kainate injections into the dorsal and median raphe nuclei

scientific article

Differential activation of spinal microglial and astroglial cells in a mouse model of peripheral neuropathic pain

scientific article published on 17 September 2009

Differential effects of intrathecally and intracerebroventricularly administered nitric oxide donors on noxious mechanical and thermal stimulation

scientific article published in November 1998

Differential effects of opioid receptor agonists on nociception and cAMP level in the spinal cord of monoarthritic rats

scientific article published in January 1992

Differential modulation of the beta-endorphin and dynorphin systems by serotonergic stimulation in the rat.

scientific article published in February 1985

Differential regulation of opioid systems in response to conditioned stress in rats.

scientific article

Differential regulation of the brain and gut immunoreactive dynorphin by the serotonin system

scientific article published in July 1985

Direct and indirect pharmacological modulation of CCL2/CCR2 pathway results in attenuation of neuropathic pain - In vivo and in vitro evidence

scientific article published on 3 May 2016

Dual Alleviation of Acute and Neuropathic Pain by Fused Opioid Agonist-Neurokinin 1 Antagonist Peptidomimetics

scientific article published on 31 October 2015

Effect of amantadine on arterial blood pressure in the rat

scientific article published on May 1, 1974

Effect of cocaine and amphetamine on biosynthesis of proenkephalin and prodynorphin in some regions of the rat limbic system.

scientific article published in July 2002

Effect of intraarticular tramadol administration in the rat model of knee joint inflammation

scientific article published on 01 September 2006

Effects of Glycogen Synthase Kinase 3beta and Cyclin-Dependent Kinase 5 Inhibitors on Morphine-Induced Analgesia and Tolerance in Rats

scientific article published on 10 August 2006

Effects of REM sleep deprivation on central alpha 1- and beta-adrenoceptors in rat brain

scientific article published in August 1986

Effects of mu and delta opioid receptor agonists and antagonists on absence epilepsy in WAG/Rij rats

scientific article

Effects of pentylenetetrazol kindling on glutamate receptor genes expression in the rat hippocampus

scientific article published in March 1998

Effects of pentylenetetrazole-induced kindling on thyrotropin-releasing hormone biosynthesis and receptors in rat brain.

scientific article published in May 1999

Effects of pilocarpine and kainate-induced seizures on N-methyl-D-aspartate receptor gene expression in the rat hippocampus

scientific article published in June 1997

Effects of pilocarpine- and kainate-induced seizures on thyrotropin-releasing hormone biosynthesis and receptors in the rat brain

scientific article

Effects of repeated MK-801 administration on the glutamate receptor gene expression in the rat hippocampus

scientific article published on August 1, 1997

Effects of repeated psychostimulant administration on the prodynorphin system activity and kappa opioid receptor density in the rat brain

scientific article published in August 1998

Effects of selective and non-selective inhibitors of nitric oxide synthase on morphine- and endomorphin-1-induced analgesia in acute and neuropathic pain in rats

scientific article published on 10 September 2013

Efficacy of tramadol in combination with doxepin or venlafaxine in inhibition of nociceptive process in the rat model of neuropathic pain: an isobolographic analysis

scientific article published in December 2009

Endogenous opioid peptides in brain and pituitary of rats with absence epilepsy

scientific article

Endomorphin-2, deltorphin II and their analogs suppress formalin-induced nociception and c-Fos expression in the rat spinal cord

scientific article published in June 2003

Ethanol withdrawal enhances the prodynorphin system activity in the rat nucleus accumbens

scientific article published in November 1997

Evidence for Fos involvement in the regulation of proenkephalin and prodynorphin gene expression in the rat hippocampus

scientific article published in March 1998

Evidence that GABA in the nucleus dorsalis raphé induces stimulation of locomotor activity and eating behavior ⬇️

scientific article published on September 11, 1979

Expression of proenkephalin (PENK) mRNA in inflammatory leukocytes during experimental peritonitis in Swiss mice

scientific article

Expression profiling of genes modulated by minocycline in a rat model of neuropathic pain

scientific article

Formalin hindpaw injection induces changes in the [3H]prazosin binding to alpha1-adrenoceptors in specific regions of the mouse brain and spinal cord

scientific article

Formalin-induced pain and mu-opioid receptor density in brain and spinal cord are modulated by A1 and A2a adenosine agonists in mice

scientific article

Full inhibition of spinal FAAH leads to TRPV1-mediated analgesic effects in neuropathic rats and possible lipoxygenase-mediated remodeling of anandamide metabolism

scientific article

Functional characterization of a novel opioid, PZM21, and its effects on the behavioural responses to morphine

scientific article published on 08 December 2019

Glial inhibitors influence the mRNA and protein levels of mGlu2/3, 5 and 7 receptors and potentiate the analgesic effects of their ligands in a mouse model of neuropathic pain

scientific article published on 25 September 2009

Glutamate receptor ligands attenuate allodynia and hyperalgesia and potentiate morphine effects in a mouse model of neuropathic pain

scientific article published on 28 April 2008

IL-1 receptor antagonist improves morphine and buprenorphine efficacy in a rat neuropathic pain model.

scientific article published in June 2015

Imipramine induces alterations in proenkephalin and prodynorphin mRNAs level in the nucleus accumbens and striatum in the rat

scientific article published on September 1, 1997

Importance of glial activation in neuropathic pain

scientific article published on 13 March 2013

Influence of doxepin used in preemptive analgesia on the nociception in the perioperative period. Experimental and clinical study

scientific article published in May 2001

Inhibition of morphine tolerance by spinal melanocortin receptor blockade

scientific article

Inhibition of nitric oxide synthase enhances antinociception mediated by mu, delta and kappa opioid receptors in acute and prolonged pain in the rat spinal cord

scientific article published in August 1997

Interleukin-1 alpha has antiallodynic and antihyperalgesic activities in a rat neuropathic pain model

scientific journal article

Intrathecal administration of doxepin attenuated development of formalin-induced pain in rats

scientific article published on 23 March 2005

Involvement of endogenous opioid peptides in fenfluramine anorexia

scientific article published in November 1986

Involvement of pro- and antinociceptive factors in minocycline analgesia in rat neuropathic pain model

scientific article published on 02 October 2014

Kappa opioid receptor agonists inhibit the pilocarpine-induced seizures and toxicity in the mouse

scientific article published on December 1994

Kappa opioid receptor agonists suppress absence seizures in WAG/Rij rats

scientific article

Knockdown of spinal opioid receptors by antisense targeting beta-arrestin reduces morphine tolerance and allodynia in rat.

scientific article published in June 2002

L-Nitroarginine methyl ester attenuates the development of morphine tolerance and dependence in mice

article

Local burn injury profoundly enhances endogenous opioid systems activity in rats

Local peripheral antinociceptive effects of 14-O-methyloxymorphone derivatives in inflammatory and neuropathic pain in the rat.

scientific article published on 25 November 2006

Local peripheral effects of mu-opioid receptor agonists in neuropathic pain in rats

scientific article

Local peripheral opioid effects and expression of opioid genes in the spinal cord and dorsal root ganglia in neuropathic and inflammatory pain

scientific article

Mechanisms and pharmacology of diabetic neuropathy - experimental and clinical studies

scientific article published on January 2013

Melanocortin 4 receptor is expressed in the dorsal root ganglions and down-regulated in neuropathic rats

scientific article published in March 2004

Mild postnatal manipulation reduces proenkephalin mRNA in the striatum in developing mice and increases morphine conditioned place preference in adulthood

scientific article

Minocycline and pentoxifylline attenuate allodynia and hyperalgesia and potentiate the effects of morphine in rat and mouse models of neuropathic pain

scientific article published on 19 January 2007

Minocycline enhances the effectiveness of nociceptin/orphanin FQ during neuropathic pain

scientific article published on 3 September 2014

Minocycline influences the anti-inflammatory interleukins and enhances the effectiveness of morphine under mice diabetic neuropathy

scientific article

Minocycline prevents dynorphin-induced neurotoxicity during neuropathic pain in rats

scientific article published on 27 August 2014

Minocycline reduces the injury-induced expression of prodynorphin and pronociceptin in the dorsal root ganglion in a rat model of neuropathic pain

scientific article published in December 2009

Modulation of melanocortin-induced changes in spinal nociception by mu-opioid receptor agonist and antagonist in neuropathic rats

scientific article

Modulation of morphine and cocaine effects by inhibition of nitric oxide synthase

Modulation of neuropathic-pain-related behaviour by the spinal endocannabinoid/endovanilloid system

scientific article published on December 2012

Monoamine involvement in the overeating caused by muscimol injection in the rat nucleus raphe dorsalis and the effects of d-fenfluramine and d-amphetamine

scientific article published in October 1983

Morphine and cocaine influence on CRF biosynthesis in the rat central nucleus of amygdala ⬇️

scientific article published on April 1, 2003

Morphine and endomorphin-1 differently influence pronociceptin/orphanin FQ system in neuropathic rats

scientific article

Morphine-induced changes in the activity of proopiomelanocortin and prodynorphin systems in zymosan-induced peritonitis in mice

scientific article published on 13 June 2005

Multifunctional Opioid-Derived Hybrids in Neuropathic Pain: Preclinical Evidence, Ideas and Challenges

scientific article published on 25 November 2020

Neuronal and immunological basis of action of antidepressants in chronic pain - clinical and experimental studies

scientific article published on January 2013

Neuropathic Pain Dysregulates Gene Expression of the Forebrain Opioid and Dopamine Systems

scientific article published on 05 February 2020

New operant model of reinstatement of food-seeking behavior in mice

scientific article published on 14 December 2010

Nitric oxide synthase inhibitor L-NAME prevents amphetamine-induced prodynorphin gene expression in the rat.

scientific article published in October 1996

Novel bifunctional hybrid compounds designed to enhance the effects of opioids and antagonize the pronociceptive effects of non-opioid peptides as potent analgesics in a rat model of neuropathic pain

scientific article published on 20 August 2020

Novel hybrid compounds, opioid agonist+melanocortin 4 receptor antagonist, as efficient analgesics in mouse neuropathic pain model

scientific article published on 01 August 2020

Opioids in chronic pain

scientific article

Opioids in neuropathic pain

scientific article

PD98059 Influences Immune Factors and Enhances Opioid Analgesia in Model of Neuropathy

scientific article published on October 2015

Pain inhibition by endomorphins

scientific article

Participation of pro- and anti-nociceptive interleukins in botulinum toxin A-induced analgesia in a rat model of neuropathic pain

scientific article published on 9 September 2016

Peripheral antinociceptive effects of MC4 receptor antagonists in a rat model of neuropathic pain - a biochemical and behavioral study

scientific article published in November 2009

Peripheral antinociceptive effects of exogenous and immune cell-derived endomorphins in prolonged inflammatory pain.

scientific article published in April 2006

Peripheral versus central antinociceptive actions of 6-amino acid-substituted derivatives of 14-O-methyloxymorphone in acute and inflammatory pain in the rat.

scientific article published on 21 September 2004

Pharmacological kynurenine 3-monooxygenase enzyme inhibition significantly reduces neuropathic pain in a rat model

scientific article published on 30 October 2015

Release of opioid peptides from the spinal cord of rats subjected to chronic pain.

scientific article published on January 1986

Repeated ethanol administration decreases prodynorphin biosynthesis in the rat hippocampus

scientific article published in January 1992

Repeated ethanol differently affects opioid peptide biosynthesis in the rat pituitary

scientific article

Sedative action of low doses of dopaminergic agents

scientific article published on January 1, 1977

Serotonergic regulation of the brain and gut beta-endorphin and dynorphin content in the rat.

scientific article published in November 1985

Spinal and local peripheral antiallodynic activity of Ro64-6198 in neuropathic pain in the rat

scientific article published on 01 July 2005

Stimulation of food intake following opioid microinjection into the nucleus accumbens septi in rats

scientific article published in September 1986

Stress prevents the chronic ethanol-induced delta opiod receptor supersensitivity in the rat brain

scientific article published in March 1990

Synthesis and biological evaluation of compact, conformationally constrained bifunctional opioid agonist - neurokinin-1 antagonist peptidomimetics

scientific article

Tapentadol - A representative of a new class of MOR-NRI analgesics

scientific article published on 31 January 2018

The action of L-dopa in rats with the raphe nuclei lesions

scientific article published on October 1, 1975

The effect of L-DOPA and L-5-hydroxytryptophan on the pentetrazole seizures in rats after lesions of the median raphe nucleus and substantia nigra

scientific article published on November 1, 1979

The effect of botulinum neurotoxin A on sciatic nerve injury-induced neuroimmunological changes in rat dorsal root ganglia and spinal cord.

scientific article

The effect of chronic morphine and cocaine administration on the Gs and Go protein messenger RNA levels in the rat hippocampus

scientific article published in December 1994

The effect of drugs of abuse on NMDAR1 receptor expression in the rat limbic system

scientific article published in November 2003

The effect of gamma-hydroxybutyrate and anticonvulsants on opioid peptide content in the rat brain

scientific article published in January 1983

The effect of intraventricularly administered noradrenaline and dopamine on the body temperature of the rat

scientific article published on January 1, 1973

The effect of lesions of dorsal or median raphe nucleus on rat behavior

scientific article published on November 1, 1977

The effect of lesions of raphe nuclei on the cataleptic action of neuroleptics

scientific article published on November 1, 1977

The effect of morphine on MC4 and CRF receptor mRNAs in the rat amygdala and attenuation of tolerance after their blockade

scientific article published in November 2003

The effect of pentoxifiline on post-injury hyperalgesia in rats and postoperative pain in patients

scientific article published in February 2000

The effect of repeated administration of morphine, cocaine and ethanol on mu and delta opioid receptor density in the nucleus accumbens and striatum of the rat.

scientific article published in January 1999

The effect of single and repeated ethanol administration of hypothalamic opioid systems activity --an in vitro release study

scientific article

The effect of single and repeated morphine administration on the prodynorphin system activity in the nucleus accumbens and striatum of the rat.

scientific article published in February 1996

The effect of some dithiocarbamic acids on dopamine-beta-hydroxylase and catecholamines level in rat's brain

scientific article published on September 1, 1975

The effects of cocaine-induced seizures on the proenkephalin mRNA level in the mouse hippocampus: a possible involvement of the nitric oxide pathway

scientific article published on February 1994

The effects of ethanol treatment on endogenous opioid peptides level and analgesia in monoarthritic rats.

scientific article

The effects of excitatory amino acids on proenkephalin and prodynorphin mRNA levels in the hippocampal dentate gyrus of the rat; an in situ hybridization study

scientific article published on January 1992

The effects of local pentoxifylline and propentofylline treatment on formalin-induced pain and tumor necrosis factor-alpha messenger RNA levels in the inflamed tissue of the rat paw.

scientific article

The glutamatergic system as a target for neuropathic pain relief

scientific article

The influence of LSD on the hind limb flexor reflex in the spinal rat

scientific article published on 01 October 1975

The influence of conditioned fear-induced stress on the opioid systems in the rat.

scientific article

The influence of dopamine-beta-hydroxylase inhibitors on avoidance reaction in rat

scientific article published on September 1, 1975

The influence of microglia activation on the efficacy of amitriptyline, doxepin, milnacipran, venlafaxine and fluoxetine in a rat model of neuropathic pain

article

The interaction of tetrahydroisoquinoline derivatives with antinociceptive action of morphine and oxotremorine in mice

scientific article published in November 2003

The multiplicity of spinal AA-5-HT anti-nociceptive action in a rat model of neuropathic pain

scientific article published on 17 June 2016

The prodynorphin system in the rat hippocampus is differentially influenced by kainic acid and pentetrazole

scientific article published in November 1992

The release of alpha-neoendorphin from rat hippocampus following kainic acid-induced seizures

scientific article published in January 1990

The role of delta-opioid receptor subtypes in neuropathic pain

scientific article published in March 2001

The role of melanocortins and their receptors in inflammatory processes, nerve regeneration and nociception

scientific article

The role of nociceptin and dynorphin in chronic pain: implications of neuro-glial interaction

scientific article published on 08 April 2011

Time-dependent changes in the activity of opioid systems in the spinal cord of monoarthritic rats--a release and in situ hybridization study

scientific article

[Dextromethorphan enhances analgesic activity of propacetamol--experimental study]

scientific article published on 01 January 2005

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