List of works - Christof Specker

Aberrant expression of the negative costimulator PD-1 on T cells in granulomatosis with polyangiitis

scientific article published on 24 March 2012

Acquired factor VIII inhibitors in nonhemophilic patients.

scientific article

An ask-the-expert service on a rheumatology web site: who were the users and what did they look for?

scientific article published on 01 April 2011

An example of internet-based quality assurance in rheumatology

scientific article

Analysis of fertility data in A.I. populations

article by F Gasteiger & Christof Specker published 1 January 1980 in Annales de génétique et de sélection animale

Analysis of fertility data in A.I. populations.

scientific article

Ankylosing spondylitis: an autoimmune disease?

scientific article

Anti-interferon alpha therapy of systemic lupus erythematosus

scientific article

Antiphospholipid antibodies in systemic lupus erythematosus and Sneddon's syndrome

scientific article published on January 1994

Antiphospholipid syndrome complicating chronic graft-versus-host disease after allogeneic bone marrow transplantation

scientific article published on 01 October 1994

Antiphospholipid syndrome in cardiac surgery-an underestimated coagulation disorder?

scientific article published on 24 February 2005

Antiphospholipid-syndrome - when to treat? ⬇️

scientific article published on August 29, 2012

Arthroscopic synovectomy and radiosynoviorthesis: a treatment option for recurrent arthritis symptoms in patients with pachydermoperiostosis.

scientific article published on 27 May 2013

BTLA Expression on Th1, Th2 and Th17 Effector T-Cells of Patients with Systemic Lupus Erythematosus Is Associated with Active Disease

scientific article published on 11 September 2019

CD134 expression on CD4+ T cells is associated with nephritis and disease activity in patients with systemic lupus erythematosus

scientific article published on 01 August 2006

CD4+CD25+ T-cell populations expressing CD134 and GITR are associated with disease activity in patients with Wegener's granulomatosis

scientific article published on 22 August 2008

Cardiovascular Comorbidity in Inflammatory Rheumatological Conditions.

scientific article

Cerebral microemboli in patients with antiphospholipid syndrome

scientific article

Cerebral microembolism in patients with Sneddon's syndrome

scientific article published on 01 March 1995

Cerebral microembolism, a disease marker for ischemic cerebrovascular events in the antiphospholipid syndrome of systemic lupus erythematosus?

scientific article published on 01 June 1999

Changing attitudes towards online electronic health records and online patient documentation in rheumatology outpatients.

scientific article published in March 2010

Clinical Spectrum Time Course in Anti Jo-1 Positive Antisynthetase Syndrome: Results From an International Retrospective Multicenter Study.

scientific article

Clinical follow-up predictors of disease pattern change in anti-Jo1 positive anti-synthetase syndrome: Results from a multicenter, international and retrospective study.

scientific article

Clinical outcomes and safety of rituximab treatment for patients with systemic lupus erythematosus (SLE) - results from a nationwide cohort in Germany (GRAID).

scientific article published in October 2013

Combination of antimalarial drugs mepacrine and chloroquine in therapy refractory cutaneous lupus erythematosus

scientific article published on February 2000

Current state of evidence on 'off-label' therapeutic options for systemic lupus erythematosus, including biological immunosuppressive agents, in Germany, Austria and Switzerland--a consensus report

scientific article

Detection of cerebral microemboli in APS--introducing a novel investigation method and implications of analogies with carotid artery disease

scientific article published on 01 January 1998

Differential diagnosis of high serum creatine kinase levels in systemic lupus erythematosus.

scientific article published on 9 May 2003

Disease-modifying anti-rheumatic drugs in rheumatoid arthritis and ankylosing spondylitis

scientific article published on July 2009

Effects of glucocorticoids in rheumatoid arthritis. Diminished glucocorticoid receptors do not result in glucocorticoid resistance.

scientific article

Efficacy and safety of rituximab treatment in patients with antineutrophil cytoplasmic antibody-associated vasculitides: results from a German registry (GRAID).

scientific article published on 15 September 2012

First Real-World Insights into Belimumab Use and Outcomes in Routine Clinical Care of Systemic Lupus Erythematosus in Germany: Results from the OBSErve Germany Study.

scientific article

Gene-expression analysis of adult-onset Still's disease and systemic juvenile idiopathic arthritis is consistent with a continuum of a single disease entity

scientific article

Genes responding to Canakinumab therapy in SJIA are -inversely - disregulated in adult onset Still's disease.

scientific article published on 28 September 2015

German guidelines for the sequential medical treatment of rheumatoid arthritis with traditional and biologic disease-modifying antirheumatic drugs

scientific article published on 14 August 2013

Germany's largest healthcare study NAKO with musculoskeletal examination program has started

scientific article published on 16 June 2016

Glucocorticoid receptors in rheumatoid arthritis

scientific article published on July 1992

HLA antigens in ankylosing spondylitis associated with Crohn's disease. Increased frequency of the HLA phenotype B27,B44.

scientific article

Health care and burden of illness in systemic lupus erythematosus compared to rheumatoid arthritis: results from the National Database of the German Collaborative Arthritis Centres.

scientific article published in January 2004

Hereditary periodic fever with systemic amyloidosis: is hyper-IgD syndrome really a benign disease?

scientific article

Hetero- and homozygosity of MHC class II gene products in systemic lupus erythematosus. The Members of the Deutsche Multizentrische SLE-Studie

scientific article published on 01 October 1991

High levels of circulating early apoptic peripheral blood mononuclear cells in systemic lupus erythematosus

scientific article published on 01 January 1998

Hyperprolactinemia in systemic lupus erythematosus?

scientific article published on 01 January 1996

Hypogonadism in Wegener's granulomatosis

scientific article published in September 2008

IL-22 production of effector CD4+ T-cells is altered in SLE patients

scientific article published on 22 July 2019

Immunoglobulin allotypes are not associated with HLA-antigens, autoantibodies and clinical symptoms in systemic lupus erythematosus. Members of the SLE Study Group

scientific article published on 01 January 1991

Immunoglobulin allotypes in systemic lupus erythematosus--results of a central European multicenter study. SLE Study Group

scientific article published on 01 January 1991

Increased expression of costimulatory markers CD134 and CD80 on interleukin-17 producing T cells in patients with systemic lupus erythematosus.

scientific article

Increased percentages of PD-1 on CD4+ T cells is associated with higher INF-γ production and altered IL-17 production in patients with systemic lupus erythematosus

scientific article published on 06 February 2014

Inhibition of joint damage and improved clinical outcomes with rituximab plus methotrexate in early active rheumatoid arthritis: the IMAGE trial

scientific article published on 11 October 2010

Internet use in rheumatology outpatients in 2006: gender less important

scientific article

Jaccoud's arthropathy in systemic lupus erythematosus: differentiation of deforming and erosive patterns by magnetic resonance imaging

scientific article published on 01 January 2003

Long-term follow-up of cyclophosphamide compared with azathioprine for initial maintenance therapy in ANCA-associated vasculitis

scientific article

Low risk of renal flares and negative outcomes in women with lupus nephritis conceiving after switching from mycophenolate mofetil to azathioprine

scientific article published on 04 February 2013

Maternal Thrombophilia and Recurrent Miscarriage - Is There Evidence That Heparin is Indicated as Prophylaxis against Recurrence?

scientific article published on 21 March 2018

Methotrexate lacks efficacy in the treatment of severe ankylosing spondylitis compared with rheumatoid and psoriatic arthritis

scientific article published on 01 June 1998

Methotrexate treatment for refractory subacute cutaneous lupus erythematosus

scientific article published on 01 April 2002

Molecular imaging of cartilage damage of finger joints in early rheumatoid arthritis with delayed gadolinium-enhanced magnetic resonance imaging.

scientific article published on February 2012

Mutations in the prostaglandin transporter encoding gene SLCO2A1 cause primary hypertrophic osteoarthropathy and isolated digital clubbing

scientific article

Nailfold Capillaroscopy Characteristics of Antisynthetase Syndrome and Possible Clinical Associations: Results of a Multicenter International Study

scientific article published on 15 November 2018

Novel 68 kDa autoantigen detected by rheumatoid arthritis specific antibodies.

scientific article

Peripheral circulating activated b-cell populations are associated with nephritis and disease activity in patients with systemic lupus erythematosus.

scientific article published on 14 September 2007

Polymorphisms of the xenobiotic-metabolizing enzymes CYP1A1 and NAT-2 in systemic sclerosis and lupus erythematosus.

scientific article published on January 1999

Pregnancy in systemic lupus erythematosus and antiphospholipid syndrome.

scientific article published in June 2017

Pregnancy outcome in patients with antiphospholipid syndrome after cerebral ischaemic events: an observational study.

scientific article published on 8 June 2012

Prevalence of lupus anticoagulant, autoimmune hemolysis, thrombocytopenia and disorders of platelet function in unselected patients with SLE

scientific article

Pulse versus daily oral cyclophosphamide for induction of remission in ANCA-associated vasculitis: long-term follow-up.

scientific article

Pulse versus daily oral cyclophosphamide for induction of remission in antineutrophil cytoplasmic antibody-associated vasculitis: a randomized trial.

scientific article

Rapid, progressive tumoral calcinosis mimicking treatment-resistant rheumatoid arthritis

scientific article published on 01 April 2012

Relapsing polychondritis in childhood--case report and short review

scientific article

RheumaNet--a novel Internet-based rheumatology information network in Germany.

scientific article

Rheumatoid arthritis: autoreactive T cells recognising a novel 68k autoantigen

scientific article published on May 1997

Rheumatology - Integration into student training (RISA) : Current structure of clinical rheumatology in German universities (RISA III)

scientific article published on 19 May 2016

Rheumatology online: A survey among the members of the German Rheumatology Society

scientific article published on August 2003

Rituximab as a treatment option for refractory endogenous anterior uveitis

scientific article published on 25 May 2007

Safety and clinical outcomes of rituximab therapy in patients with different autoimmune diseases: experience from a national registry (GRAID).

scientific article published on 13 May 2011

Self-assessments of patients via Tablet PC in routine patient care: comparison with standardised paper questionnaires.

scientific article

Serum Jo-1 Autoantibody and Isolated Arthritis in the Antisynthetase Syndrome: Review of the Literature and Report of the Experience of AENEAS Collaborative Group.

scientific article

Successful outcome of two pregnancies in patients with adult-onset Still's disease treated with IL-1 receptor antagonist (anakinra)

scientific article published on 01 November 2011

Swimming against the stream: the fishbowl discussion method as an interactive tool for medical conferences: experiences from the 11th European Lupus Meeting

scientific article published on 02 November 2018

Synovitis and bone inflammation in early rheumatoid arthritis: high-resolution multi-pinhole SPECT versus MRI.

scientific article published on 13 December 2012

The European Society for Immunodeficiencies (ESID) registry 2014

The German National Registry of Primary Immunodeficiencies (2012-2017)

scientific article published on 19 July 2019

The LUNAR study: rituximab for lupus nephritis? ⬇️

scientific article published on April 1, 2013

The p68 autoantigen characteristic of rheumatoid arthritis is reactive with carbohydrate epitope specific autoantibodies

scientific article

Timing of onset affects arthritis presentation pattern in antisyntethase syndrome

scientific article published on 26 July 2017

Tocilizumab monotherapy versus adalimumab monotherapy for treatment of rheumatoid arthritis (ADACTA): a randomised, double-blind, controlled phase 4 trial

scientific article published on 18 March 2013

Utility of combined high-resolution bone SPECT and MRI for the identification of rheumatoid arthritis patients with high-risk for erosive progression.

scientific article published on 20 November 2012

[Amendment of the structural quality for inpatient rheumatology. A forward-looking concept]

scientific article published on 01 September 2011

[Antiphospholipid syndrome]

scientific article published on 01 February 2007

[Antiphospholipid syndrome]

scientific article published on 01 April 2015

[Antiphospholipid syndrome]

scientific article published on 01 August 2016

[Arthralgia plus positive treatment of rheumatoid arthritis - no]

scientific article published on 02 September 2014

[Arthropathy in beta-thalassemia minor]

scientific article published on 01 January 2000

[Association of HLA-antigens with systemic lupus erythematodes and its symptoms (author's transl)]

scientific article published on 01 May 1982

[Cardiac manifestations of rheumatic diseases]

scientific article published on 01 March 2006

[Differentiated laboratory diagnostics of rheumatic diseases]

scientific article published on 01 November 2018

[Digital Health in Rheumatology - Status 2018/19]

scientific article published on 01 April 2019

[Digital Health in Rheumatology - Status 2018/19]

scientific article published on 29 March 2019

[Disease-oriented Internet use in outpatients with inflammatory rheumatic diseases]

scientific article published on 01 June 2004

[Documentation concepts in MedNet-Rheuma (competence network "Inflammatory-rheumatic systemic diseases")]

scientific article published on 01 February 2000

[Early diagnosis of rheumatoid arthritis]

scientific article published on 01 November 2005

[German 2012 guidelines for the sequential medical treatment of rheumatoid arthritis. Adapted EULAR recommendations and updated treatment algorithm]

scientific article published on 01 September 2012

[Hot topic: direct oral anticoagulants (DOAC) in antiphospholipid syndrome?]

scientific article published on 01 August 2019

[Ormond's disease and chronic venous obstruction]

[Presentation of the Dusseldorf Competence Center]

scientific article published on 01 October 2001

[RA-specific autoantibodies against a 68k antigen]

scientific article published on 01 March 1997

[Regional cooperative rheumatology centers : Networking of rheumatology in Germany for over 25 years]

scientific article published on 01 December 2020

[S2e guideline: treatment of rheumatoid arthritis with disease-modifying drugs]

scientific article published on 01 August 2018

[Significant association of HLA-B8 with systemic lupus erythematosus and with specific serological markers]

scientific article published on 01 April 1987

[Systemic lupus erythematosus in men--a different prognosis?]

scientific article published on 01 November 1994

[The heart in rheumatic diseases]

scientific article published on 01 March 2007

List of works by Christof Specker

Aberrant expression of the negative costimulator PD-1 on T cells in granulomatosis with polyangiitis

Acquired factor VIII inhibitors in nonhemophilic patients.

An ask-the-expert service on a rheumatology web site: who were the users and what did they look for?

An example of internet-based quality assurance in rheumatology

Analysis of fertility data in A.I. populations

Analysis of fertility data in A.I. populations.

Ankylosing spondylitis: an autoimmune disease?

Anti-interferon alpha therapy of systemic lupus erythematosus

Antiphospholipid antibodies in systemic lupus erythematosus and Sneddon's syndrome

Antiphospholipid syndrome complicating chronic graft-versus-host disease after allogeneic bone marrow transplantation

Antiphospholipid syndrome in cardiac surgery-an underestimated coagulation disorder?

Antiphospholipid-syndrome - when to treat? ⬇️

Arthroscopic synovectomy and radiosynoviorthesis: a treatment option for recurrent arthritis symptoms in patients with pachydermoperiostosis.

BTLA Expression on Th1, Th2 and Th17 Effector T-Cells of Patients with Systemic Lupus Erythematosus Is Associated with Active Disease

CD134 expression on CD4+ T cells is associated with nephritis and disease activity in patients with systemic lupus erythematosus

CD4+CD25+ T-cell populations expressing CD134 and GITR are associated with disease activity in patients with Wegener's granulomatosis

Cardiovascular Comorbidity in Inflammatory Rheumatological Conditions.

Cerebral microemboli in patients with antiphospholipid syndrome

Cerebral microembolism in patients with Sneddon's syndrome

Cerebral microembolism, a disease marker for ischemic cerebrovascular events in the antiphospholipid syndrome of systemic lupus erythematosus?

Changing attitudes towards online electronic health records and online patient documentation in rheumatology outpatients.

Clinical Spectrum Time Course in Anti Jo-1 Positive Antisynthetase Syndrome: Results From an International Retrospective Multicenter Study.

Clinical follow-up predictors of disease pattern change in anti-Jo1 positive anti-synthetase syndrome: Results from a multicenter, international and retrospective study.

Clinical outcomes and safety of rituximab treatment for patients with systemic lupus erythematosus (SLE) - results from a nationwide cohort in Germany (GRAID).

Combination of antimalarial drugs mepacrine and chloroquine in therapy refractory cutaneous lupus erythematosus

Current state of evidence on 'off-label' therapeutic options for systemic lupus erythematosus, including biological immunosuppressive agents, in Germany, Austria and Switzerland--a consensus report

Detection of cerebral microemboli in APS--introducing a novel investigation method and implications of analogies with carotid artery disease

Differential diagnosis of high serum creatine kinase levels in systemic lupus erythematosus.

Disease-modifying anti-rheumatic drugs in rheumatoid arthritis and ankylosing spondylitis

Effects of glucocorticoids in rheumatoid arthritis. Diminished glucocorticoid receptors do not result in glucocorticoid resistance.

Efficacy and safety of rituximab treatment in patients with antineutrophil cytoplasmic antibody-associated vasculitides: results from a German registry (GRAID).

First Real-World Insights into Belimumab Use and Outcomes in Routine Clinical Care of Systemic Lupus Erythematosus in Germany: Results from the OBSErve Germany Study.

Gene-expression analysis of adult-onset Still's disease and systemic juvenile idiopathic arthritis is consistent with a continuum of a single disease entity

Genes responding to Canakinumab therapy in SJIA are -inversely - disregulated in adult onset Still's disease.

German guidelines for the sequential medical treatment of rheumatoid arthritis with traditional and biologic disease-modifying antirheumatic drugs

Germany's largest healthcare study NAKO with musculoskeletal examination program has started

Glucocorticoid receptors in rheumatoid arthritis

HLA antigens in ankylosing spondylitis associated with Crohn's disease. Increased frequency of the HLA phenotype B27,B44.

Health care and burden of illness in systemic lupus erythematosus compared to rheumatoid arthritis: results from the National Database of the German Collaborative Arthritis Centres.

Hereditary periodic fever with systemic amyloidosis: is hyper-IgD syndrome really a benign disease?

Hetero- and homozygosity of MHC class II gene products in systemic lupus erythematosus. The Members of the Deutsche Multizentrische SLE-Studie

High levels of circulating early apoptic peripheral blood mononuclear cells in systemic lupus erythematosus

Hyperprolactinemia in systemic lupus erythematosus?

Hypogonadism in Wegener's granulomatosis

IL-22 production of effector CD4+ T-cells is altered in SLE patients

Immunoglobulin allotypes are not associated with HLA-antigens, autoantibodies and clinical symptoms in systemic lupus erythematosus. Members of the SLE Study Group

Immunoglobulin allotypes in systemic lupus erythematosus--results of a central European multicenter study. SLE Study Group

Increased expression of costimulatory markers CD134 and CD80 on interleukin-17 producing T cells in patients with systemic lupus erythematosus.

Increased percentages of PD-1 on CD4+ T cells is associated with higher INF-γ production and altered IL-17 production in patients with systemic lupus erythematosus

Inhibition of joint damage and improved clinical outcomes with rituximab plus methotrexate in early active rheumatoid arthritis: the IMAGE trial

Internet use in rheumatology outpatients in 2006: gender less important

Jaccoud's arthropathy in systemic lupus erythematosus: differentiation of deforming and erosive patterns by magnetic resonance imaging

Long-term follow-up of cyclophosphamide compared with azathioprine for initial maintenance therapy in ANCA-associated vasculitis

Low risk of renal flares and negative outcomes in women with lupus nephritis conceiving after switching from mycophenolate mofetil to azathioprine

Maternal Thrombophilia and Recurrent Miscarriage - Is There Evidence That Heparin is Indicated as Prophylaxis against Recurrence?

Methotrexate lacks efficacy in the treatment of severe ankylosing spondylitis compared with rheumatoid and psoriatic arthritis

Methotrexate treatment for refractory subacute cutaneous lupus erythematosus

Molecular imaging of cartilage damage of finger joints in early rheumatoid arthritis with delayed gadolinium-enhanced magnetic resonance imaging.

Mutations in the prostaglandin transporter encoding gene SLCO2A1 cause primary hypertrophic osteoarthropathy and isolated digital clubbing

Nailfold Capillaroscopy Characteristics of Antisynthetase Syndrome and Possible Clinical Associations: Results of a Multicenter International Study

Novel 68 kDa autoantigen detected by rheumatoid arthritis specific antibodies.

Peripheral circulating activated b-cell populations are associated with nephritis and disease activity in patients with systemic lupus erythematosus.

Polymorphisms of the xenobiotic-metabolizing enzymes CYP1A1 and NAT-2 in systemic sclerosis and lupus erythematosus.

Pregnancy in systemic lupus erythematosus and antiphospholipid syndrome.

Pregnancy outcome in patients with antiphospholipid syndrome after cerebral ischaemic events: an observational study.

Prevalence of lupus anticoagulant, autoimmune hemolysis, thrombocytopenia and disorders of platelet function in unselected patients with SLE

Pulse versus daily oral cyclophosphamide for induction of remission in ANCA-associated vasculitis: long-term follow-up.

Pulse versus daily oral cyclophosphamide for induction of remission in antineutrophil cytoplasmic antibody-associated vasculitis: a randomized trial.

Rapid, progressive tumoral calcinosis mimicking treatment-resistant rheumatoid arthritis

Relapsing polychondritis in childhood--case report and short review

RheumaNet--a novel Internet-based rheumatology information network in Germany.

Rheumatoid arthritis: autoreactive T cells recognising a novel 68k autoantigen

Rheumatology - Integration into student training (RISA) : Current structure of clinical rheumatology in German universities (RISA III)

Rheumatology online: A survey among the members of the German Rheumatology Society

Rituximab as a treatment option for refractory endogenous anterior uveitis

Safety and clinical outcomes of rituximab therapy in patients with different autoimmune diseases: experience from a national registry (GRAID).

Self-assessments of patients via Tablet PC in routine patient care: comparison with standardised paper questionnaires.

Serum Jo-1 Autoantibody and Isolated Arthritis in the Antisynthetase Syndrome: Review of the Literature and Report of the Experience of AENEAS Collaborative Group.

Successful outcome of two pregnancies in patients with adult-onset Still's disease treated with IL-1 receptor antagonist (anakinra)