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List of works by Philippe Roche

18F-FDOPA PET/CT imaging of MAX-related pheochromocytoma.

scientific article published on 8 March 2018

2P2I HUNTER: a tool for filtering orthosteric protein-protein interaction modulators via a dedicated support vector machine.

scientific article

2P2Idb v2: update of a structural database dedicated to orthosteric modulation of protein-protein interactions.

scientific article published on 15 March 2016

2P2Idb: a structural database dedicated to orthosteric modulation of protein-protein interactions.

scientific article

A divergent CheW confers plasticity to nucleoid-associated chemosensory arrays

scientific article published on 20 December 2019

Aminoacylase 1-catalysed deacetylation of bioactives epoxides mycotoxin-derived mercapturates; 3,4-epoxyprecocenes as models of cytotoxic epoxides

scientific article published on 11 February 2012

Chemical libraries dedicated to protein-protein interactions

scientific article

Chemistry-driven Hit-to-lead Optimization Guided by Structure-based Approaches

scientific article published on 27 July 2018

Computational studies of human galectin-1: role of conserved tryptophan residue in stacking interaction with carbohydrate ligands.

scientific article published in August 2009

CovaDOTS: In Silico Chemistry-Driven Tool to Design Covalent Inhibitors Using a Linking Strategy

scientific article published on 05 April 2019

Exploring Selective Inhibition of the First Bromodomain of the Human Bromodomain and Extra-terminal Domain (BET) Proteins

scientific article

Focused chemical libraries--design and enrichment: an example of protein-protein interaction chemical space

scientific article

Genetic, structural, and chemical insights into the dual function of GRASP55 in germ cell Golgi remodeling and JAM-C polarized localization during spermatogenesis.

scientific article

Implications of SDHB genetic testing in patients with sporadic pheochromocytoma.

scientific article published on 22 February 2017

In Rhizobium meliloti, the operon associated with the nod box n5 comprises nodL, noeA and noeB, three host-range genes specifically required for the nodulation of particular Medicago species.

scientific article published on August 1995

Integrated Strategy for Lead Optimization Based on Fragment Growing: The Diversity-Oriented-Target-Focused-Synthesis Approach

scientific article published on 22 June 2018

MEMO associated with an ErbB2 receptor phosphopeptide reveals a new phosphotyrosine motif

scientific article

Missense mutations in the homeodomain of HOXD13 are associated with brachydactyly types D and E.

scientific article

Modeling study of human renal chloride channel (hCLC-5) mutations suggests a structural-functional relationship.

scientific article

Modified cap group suberoylanilide hydroxamic acid histone deacetylase inhibitor derivatives reveal improved selective antileukemic activity.

scientific article published on April 2010

Molecular basis of symbiotic host specificity in Rhizobium meliloti: nodH and nodPQ genes encode the sulfation of lipo-oligosaccharide signals

scientific article published on 01 December 1991

Molecular dynamics of the FixJ receiver domain: movement of the beta4-alpha4 loop correlates with the in and out flip of Phe101.

scientific article

Multiscaled exploration of coupled folding and binding of an intrinsically disordered molecular recognition element in measles virus nucleoprotein.

scientific article published on 16 September 2013

NMR and MD investigations of human galectin-1/oligosaccharide complexes

scientific article

Protein-Protein Interaction Inhibition (2P2I)-Oriented Chemical Library Accelerates Hit Discovery

scientific article

Reply to Jensen and Blackledge: Dual quantifications of intrinsically disordered proteins by NMR ensembles and molecular dynamics simulations

scientific article published on April 2014

Stereoselective synthesis of original spirolactams displaying promising folded structures.

scientific article published on 13 June 2013

Structural determination of bacterial nodulation factors involved in the Rhizobium meliloti-alfalfa symbiosis

scientific article published on 01 June 1991

Structures of three HIV-1 HLA-B*5703-peptide complexes and identification of related HLAs potentially associated with long-term nonprogression.

scientific article published in August 2005

Symbiotic and taxonomic diversity of rhizobia isolated from Acacia tortilis subsp. raddiana in Africa.

scientific article

Symbiotic host-specificity of Rhizobium meliloti is determined by a sulphated and acylated glucosamine oligosaccharide signal

scientific article published in Nature

The common nodABC genes of Rhizobium meliloti are host-range determinants.

scientific article published on December 1996

The lipo-oligosaccharidic symbiotic signals of Rhizobium meliloti

scientific article published on May 1, 1992

[How is transcription reinitiation governed in measles virus?]

scientific article

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