List of works - Honorine D Ward

A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium

scientific article

AIDS-associated diarrhea and wasting in Northeast Brazil is associated with subtherapeutic plasma levels of antiretroviral medications and with both bovine and human subtypes of Cryptosporidium parvum

scientific article

An early intestinal mucosal source of gamma interferon is associated with resistance to and control of Cryptosporidium parvum infection in mice

scientific article published on December 2005

Analysis of human immune responses in quasi-experimental settings: tutorial in biostatistics

scientific article

Analysis of sequence diversity at the highly polymorphic Cpgp40/15 locus among Cryptosporidium isolates from human immunodeficiency virus-infected children in South Africa

scientific article

Antibiotic treatment of diarrhoea is associated with decreased time to the next diarrhoea episode among young children in Vellore, India

scientific article

Antibody responses to the immunodominant Cryptosporidium gp15 antigen and gp15 polymorphisms in a case-control study of cryptosporidiosis in children in Bangladesh

scientific article

Apical organelle discharge by Cryptosporidium parvum is temperature, cytoskeleton, and intracellular calcium dependent and required for host cell invasion

scientific article published on December 2004

Associations of cocaine use and HIV infection with the intestinal microbiota, microbial translocation, and inflammation

scientific article

Brief Report: Estimating Differences and Ratios in Median Times to Event

scientific article published on 22 July 2016

Burden of childhood diseases and malnutrition in a semi-urban slum in southern India

scientific article

Burden of diarrhea, hospitalization and mortality due to cryptosporidial infections in Indian children

scientific article

Childhood malnutrition and the intestinal microbiome

scientific article

Clinical features & risk factors associated with cryptosporidiosis in HIV infected adults in India

scientific article published on December 2007

Complete cryspovirus genome sequences from Cryptosporidium parvum isolate Iowa

scientific article published on 5 May 2017

Cryptosporidiosis among Bangladeshi children with diarrhea: a prospective, matched, case-control study of clinical features, epidemiology and systemic antibody responses

article

Cryptosporidiosis among children in an endemic semiurban community in southern India: does a protected drinking water source decrease infection?

scientific article published on 24 May 2013

Cryptosporidiosis in HIV/AIDS patients in Kenya: clinical features, epidemiology, molecular characterization and antibody responses

scientific article

Cryptosporidiosis: biology, pathogenesis and disease

scientific article

Cryptosporidium p30, a galactose/N-acetylgalactosamine-specific lectin, mediates infection in vitro

scientific article published on 28 September 2007

Cryptosporidium parvum glycoprotein gp40 localizes to the sporozoite surface by association with gp15.

scientific article published on 21 July 2007

Cryptosporidium parvum scavenges LDL-derived cholesterol and micellar cholesterol internalized into enterocytes ⬇️

scientific article published on 28 January 2013

Early Life Antibiotic Exposure Is Not Associated with Growth in Young Children of Vellore, India

scientific article published on 11 September 2015

Environmental Factors Associated with High Fly Densities and Diarrhea in Vellore, India

scientific article

Evidence for mucin-like glycoproteins that tether sporozoites of Cryptosporidium parvum to the inner surface of the oocyst wall

scientific article

Expression of the highly polymorphic Cryptosporidium parvum Cpgp40/15 gene in genotype I and II isolates

scientific article published on February 2002

From hospitalization records to surveillance: The use of local patient profiles to characterize cholera in Vellore, India

scientific article

Genetic diversity of Cryptosporidium spp. from Bangladeshi children

scientific article

Human CD8(+) T cells clear Cryptosporidium parvum from infected intestinal epithelial cells

scientific article

Human immune responses in cryptosporidiosis

scientific article published on March 2010

Identification and characterization of Cryptosporidium parvum Clec, a novel C-type lectin domain-containing mucin-like glycoprotein

scientific article published on July 2013

Identification of Cpgp40/15 Type Ib as the predominant allele in isolates of Cryptosporidium spp. from a waterborne outbreak of gastroenteritis in South Burgundy, France

scientific article

Identification of a family of four UDP-polypeptide N-acetylgalactosaminyl transferases in Cryptosporidium species

scientific article published on 13 August 2013

Immune response and intestinal permeability in children with acute gastroenteritis treated with Lactobacillus rhamnosus GG: a randomized, double-blind, placebo-controlled trial

scientific article published on 5 February 2014

Implications of acquired environmental enteric dysfunction for growth and stunting in infants and children living in low- and middle-income countries

scientific article

Infectious diarrhoea in antiretroviral therapy-naive HIV/AIDS patients in Kenya

scientific article published on October 2013

Intestinal microbiota, microbial translocation, and systemic inflammation in chronic HIV infection

scientific article

Intestinal protozoal parasites and diarrheal disease in Bangladesh

scientific article published on 01 May 2009

Investigation of Potential Zoonotic Transmission of Cryptosporidiosis in Southern India ⬇️

scientific article published on October 1, 2011

Longitudinal Analysis of the Intestinal Microbiota in Persistently Stunted Young Children in South India

scientific article

Molecular and spatial epidemiology of cryptosporidiosis in children in a semiurban community in South India

scientific article published on 24 January 2007

Molecular basis of Cryptosporidium-host cell interactions: recent advances and future prospects

scientific article published on August 2006

Multilocus genotyping of Cryptosporidium sp. isolates from human immunodeficiency virus-infected individuals in South India

scientific article published on February 2006

Multisite study of cryptosporidiosis in children with diarrhea in India

scientific article

Natural History of Cryptosporidiosis in a Birth Cohort in Southern India

scientific article

New Tools for Cryptosporidium Lead to New Hope for Cryptosporidiosis

scientific article

Novel Bioengineered Three-Dimensional Human Intestinal Model for Long-Term Infection of Cryptosporidium parvum

scientific article published on 4 January 2017

Polyclonal Fab phage display libraries with a high percentage of diverse clones to Cryptosporidium parvum glycoproteins

scientific article

Polymorphic mucin antigens CpMuc4 and CpMuc5 are integral to Cryptosporidium parvum infection in vitro

scientific article published on 23 January 2009

Proteolytic processing of the Cryptosporidium glycoprotein gp40/15 by human furin and by a parasite-derived furin-like protease activity

scientific article published on 16 October 2006

Quantification of in vitro and in vivo Cryptosporidium parvum infection by using real-time PCR.

scientific article

Recent Breakthroughs and Ongoing Limitations in Research

Reduction in diarrhoeal rates through interventions that prevent unnecessary antibiotic exposure early in life in an observational birth cohort

scientific article published on 30 November 2015

Release of luminal exosomes contributes to TLR4-mediated epithelial antimicrobial defense

scientific article

Risk factors for cryptosporidiosis among children in a semi urban slum in southern India: a nested case-control study

scientific article

Role of CpSUB1, a subtilisin-like protease, in Cryptosporidium parvum infection in vitro

scientific article

Seasonality of Cryptosporidium oocyst detection in surface waters of Meru, Kenya as determined by two isolation methods followed by PCR

scientific article (publication date: March 2009)

Seasonality of rotavirus in South Asia: a meta-analysis approach assessing associations with temperature, precipitation, and vegetation index.

scientific article published on 31 May 2012

Seasonality of water quality and diarrheal disease counts in urban and rural settings in south India

scientific article published on 12 February 2016

Serum Anti-Cryptosporidial gp15 Antibodies in Mothers and Children Less than 2 Years of Age in India

scientific article

Serum Antibody Responses to Polymorphic Cryptosporidium Mucin Antigen in Bangladeshi Children with Cryptosporidiosis ⬇️

scientific article published on September 1, 2011

Serum IgG response to Cryptosporidium immunodominant antigen gp15 and polymorphic antigen gp40 in children with cryptosporidiosis in South India

scientific article

Serum IgG responses and seroconversion patterns to Cryptosporidium gp15 among children in a birth cohort in south India

scientific article

Stable expression of Cryptosporidium parvum glycoprotein gp40/15 in Toxoplasma gondii

scientific article published on 7 January 2007

Symptomatic and asymptomatic Cryptosporidium infections in children in a semi-urban slum community in southern India

scientific article

Systemic and Mucosal Immune Responses to Cryptosporidium-Vaccine Development

scientific article

Systemic antibody responses to the immunodominant p23 antigen and p23 polymorphisms in children with cryptosporidiosis in Bangladesh

scientific article published on February 2012

The Cryptosporidium parvum C-Type Lectin CpClec Mediates Infection of Intestinal Epithelial Cells via Interactions with Sulfated Proteoglycans

scientific article published on 14 March 2016

The effect of early life antibiotic exposures on diarrheal rates among young children in Vellore, India

scientific article published on June 2015

The first 1000 days of life: prenatal and postnatal risk factors for morbidity and growth in a birth cohort in southern India

scientific article

The state of research for AIDS-associated opportunistic infections and the importance of sustaining smaller research communities

scientific article published on 9 December 2011

Zinc or multiple micronutrient supplementation to reduce diarrhea and respiratory disease in South African children: a randomized controlled trial

scientific article

List of works by Honorine D Ward

A review of the global burden, novel diagnostics, therapeutics, and vaccine targets for cryptosporidium

AIDS-associated diarrhea and wasting in Northeast Brazil is associated with subtherapeutic plasma levels of antiretroviral medications and with both bovine and human subtypes of Cryptosporidium parvum

An early intestinal mucosal source of gamma interferon is associated with resistance to and control of Cryptosporidium parvum infection in mice

Analysis of human immune responses in quasi-experimental settings: tutorial in biostatistics

Analysis of sequence diversity at the highly polymorphic Cpgp40/15 locus among Cryptosporidium isolates from human immunodeficiency virus-infected children in South Africa

Antibiotic treatment of diarrhoea is associated with decreased time to the next diarrhoea episode among young children in Vellore, India

Antibody responses to the immunodominant Cryptosporidium gp15 antigen and gp15 polymorphisms in a case-control study of cryptosporidiosis in children in Bangladesh

Apical organelle discharge by Cryptosporidium parvum is temperature, cytoskeleton, and intracellular calcium dependent and required for host cell invasion

Associations of cocaine use and HIV infection with the intestinal microbiota, microbial translocation, and inflammation

Brief Report: Estimating Differences and Ratios in Median Times to Event

Burden of childhood diseases and malnutrition in a semi-urban slum in southern India

Burden of diarrhea, hospitalization and mortality due to cryptosporidial infections in Indian children

Childhood malnutrition and the intestinal microbiome

Clinical features & risk factors associated with cryptosporidiosis in HIV infected adults in India

Complete cryspovirus genome sequences from Cryptosporidium parvum isolate Iowa

Cryptosporidiosis among Bangladeshi children with diarrhea: a prospective, matched, case-control study of clinical features, epidemiology and systemic antibody responses

Cryptosporidiosis among children in an endemic semiurban community in southern India: does a protected drinking water source decrease infection?

Cryptosporidiosis in HIV/AIDS patients in Kenya: clinical features, epidemiology, molecular characterization and antibody responses

Cryptosporidiosis: biology, pathogenesis and disease

Cryptosporidium p30, a galactose/N-acetylgalactosamine-specific lectin, mediates infection in vitro

Cryptosporidium parvum glycoprotein gp40 localizes to the sporozoite surface by association with gp15.

Cryptosporidium parvum scavenges LDL-derived cholesterol and micellar cholesterol internalized into enterocytes ⬇️

Early Life Antibiotic Exposure Is Not Associated with Growth in Young Children of Vellore, India

Environmental Factors Associated with High Fly Densities and Diarrhea in Vellore, India

Evidence for mucin-like glycoproteins that tether sporozoites of Cryptosporidium parvum to the inner surface of the oocyst wall

Expression of the highly polymorphic Cryptosporidium parvum Cpgp40/15 gene in genotype I and II isolates

From hospitalization records to surveillance: The use of local patient profiles to characterize cholera in Vellore, India

Genetic diversity of Cryptosporidium spp. from Bangladeshi children

Human CD8(+) T cells clear Cryptosporidium parvum from infected intestinal epithelial cells

Human immune responses in cryptosporidiosis

Identification and characterization of Cryptosporidium parvum Clec, a novel C-type lectin domain-containing mucin-like glycoprotein

Identification of Cpgp40/15 Type Ib as the predominant allele in isolates of Cryptosporidium spp. from a waterborne outbreak of gastroenteritis in South Burgundy, France

Identification of a family of four UDP-polypeptide N-acetylgalactosaminyl transferases in Cryptosporidium species

Immune response and intestinal permeability in children with acute gastroenteritis treated with Lactobacillus rhamnosus GG: a randomized, double-blind, placebo-controlled trial

Implications of acquired environmental enteric dysfunction for growth and stunting in infants and children living in low- and middle-income countries

Infectious diarrhoea in antiretroviral therapy-naive HIV/AIDS patients in Kenya

Intestinal microbiota, microbial translocation, and systemic inflammation in chronic HIV infection

Intestinal protozoal parasites and diarrheal disease in Bangladesh

Investigation of Potential Zoonotic Transmission of Cryptosporidiosis in Southern India ⬇️

Longitudinal Analysis of the Intestinal Microbiota in Persistently Stunted Young Children in South India

Molecular and spatial epidemiology of cryptosporidiosis in children in a semiurban community in South India

Molecular basis of Cryptosporidium-host cell interactions: recent advances and future prospects

Multilocus genotyping of Cryptosporidium sp. isolates from human immunodeficiency virus-infected individuals in South India

Multisite study of cryptosporidiosis in children with diarrhea in India

Natural History of Cryptosporidiosis in a Birth Cohort in Southern India

New Tools for Cryptosporidium Lead to New Hope for Cryptosporidiosis

Novel Bioengineered Three-Dimensional Human Intestinal Model for Long-Term Infection of Cryptosporidium parvum

Polyclonal Fab phage display libraries with a high percentage of diverse clones to Cryptosporidium parvum glycoproteins

Polymorphic mucin antigens CpMuc4 and CpMuc5 are integral to Cryptosporidium parvum infection in vitro

Proteolytic processing of the Cryptosporidium glycoprotein gp40/15 by human furin and by a parasite-derived furin-like protease activity

Quantification of in vitro and in vivo Cryptosporidium parvum infection by using real-time PCR.

Recent Breakthroughs and Ongoing Limitations in Research

Reduction in diarrhoeal rates through interventions that prevent unnecessary antibiotic exposure early in life in an observational birth cohort

Release of luminal exosomes contributes to TLR4-mediated epithelial antimicrobial defense

Risk factors for cryptosporidiosis among children in a semi urban slum in southern India: a nested case-control study

Role of CpSUB1, a subtilisin-like protease, in Cryptosporidium parvum infection in vitro

Seasonality of Cryptosporidium oocyst detection in surface waters of Meru, Kenya as determined by two isolation methods followed by PCR

Seasonality of rotavirus in South Asia: a meta-analysis approach assessing associations with temperature, precipitation, and vegetation index.

Seasonality of water quality and diarrheal disease counts in urban and rural settings in south India

Serum Anti-Cryptosporidial gp15 Antibodies in Mothers and Children Less than 2 Years of Age in India

Serum Antibody Responses to Polymorphic Cryptosporidium Mucin Antigen in Bangladeshi Children with Cryptosporidiosis ⬇️

Serum IgG response to Cryptosporidium immunodominant antigen gp15 and polymorphic antigen gp40 in children with cryptosporidiosis in South India

Serum IgG responses and seroconversion patterns to Cryptosporidium gp15 among children in a birth cohort in south India

Stable expression of Cryptosporidium parvum glycoprotein gp40/15 in Toxoplasma gondii

Symptomatic and asymptomatic Cryptosporidium infections in children in a semi-urban slum community in southern India

Systemic and Mucosal Immune Responses to Cryptosporidium-Vaccine Development

Systemic antibody responses to the immunodominant p23 antigen and p23 polymorphisms in children with cryptosporidiosis in Bangladesh

The Cryptosporidium parvum C-Type Lectin CpClec Mediates Infection of Intestinal Epithelial Cells via Interactions with Sulfated Proteoglycans

The effect of early life antibiotic exposures on diarrheal rates among young children in Vellore, India

The first 1000 days of life: prenatal and postnatal risk factors for morbidity and growth in a birth cohort in southern India

The state of research for AIDS-associated opportunistic infections and the importance of sustaining smaller research communities

Zinc or multiple micronutrient supplementation to reduce diarrhea and respiratory disease in South African children: a randomized controlled trial