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List of works by Steinunn Baekkeskov

A beta-cell glycoprotein of Mr 40 000 is the major rat islet cell immunogen following xenogenic immunisation

scientific article published on 01 July 1984

A combination of three distinct trafficking signals mediates axonal targeting and presynaptic clustering of GAD65

scientific article

A non-cleavable mutant of Fas ligand does not prevent neutrophilic destruction of islet transplants.

scientific article published on May 2000

Aberrant Accumulation of the Diabetes Autoantigen GAD65 in Golgi Membranes in Conditions of ER Stress and Autoimmunity

scientific article published on 9 June 2016

Advances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation.

scientific article

Antibodies to a Mr-64000 islet cell protein in Swedish children with newly diagnosed Type 1 (insulin-dependent) diabetes

scientific article published on 01 August 1988

Autoantibodies in newly diagnosed diabetic children immunoprecipitate human pancreatic islet cell proteins

scientific article published in Nature

Autoreactive epitopes defined by diabetes-associated human monoclonal antibodies are localized in the middle and C-terminal domains of the smaller form of glutamate decarboxylase ⬇️

scientific article published on April 1, 1993

Bioengineering strategies for inducing tolerance in autoimmune diabetes

scientific article

Cellular and subcellular localization of an Mr 64,000 protein autoantigen in insulin-dependent diabetes.

scientific article

Compartmentalization of GABA synthesis by GAD67 differs between pancreatic beta cells and neurons

scientific article published on 3 February 2015

Coordinate expression of the endogenous p53 gene in beta cells of transgenic mice expressing hybrid insulin-SV40 T antigen genes

scientific article published on September 1987

Corrigendum: Advances in pancreatic islet monolayer culture on glass surfaces enable super-resolution microscopy and insights into beta cell ciliogenesis and proliferation.

scientific article

Differential expression of GAD65 and GAD67 in human, rat, and mouse pancreatic islets.

scientific article published on December 1993

Differential protection in two transgenic lines of NOD/Lt mice hyperexpressing the autoantigen GAD65 in pancreatic beta-cells.

scientific article published in December 1998

Does GAD have a unique role in triggering IDDM?

scientific article

Epilepsy in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase

scientific article

Fas ligand expression in islets of Langerhans does not confer immune privilege and instead targets them for rapid destruction ⬇️

scientific article published on July 1, 1997

Glucose stimulates the biosynthesis of a human pancreatic islet cell protein detected by an antiserum against the human erythrocyte glucose transporter

scientific article published on 01 July 1983

Glutamate decarboxylase and GABA in pancreatic islets: lessons from knock-out mice.

scientific article published on May 1999

High-resolution autoreactive epitope mapping and structural modeling of the 65 kDa form of human glutamic acid decarboxylase

scientific article published on 01 April 1999

Higher autoantibody levels and recognition of a linear NH2-terminal epitope in the autoantigen GAD65, distinguish stiff-man syndrome from insulin-dependent diabetes mellitus.

scientific article

Homing of GAD65 specific autoimmunity and development of insulitis requires expression of both DQ8 and human GAD65 in transgenic mice.

scientific article published on 16 March 2009

Identification and characterization of glima 38, a glycosylated islet cell membrane antigen, which together with GAD65 and IA2 marks the early phases of autoimmune response in type 1 diabetes.

scientific article published on June 1996

Identification of the 64K autoantigen in insulin-dependent diabetes as the GABA-synthesizing enzyme glutamic acid decarboxylase ⬇️

scientific article published on September 13, 1990

Immunoreactivity to a 64,000 Mr human islet cell antigen in sera from insulin-dependent diabetes mellitus patients and individuals with abnormal glucose tolerance

scientific article published on 01 April 1986

Increased anxiety and altered responses to anxiolytics in mice deficient in the 65-kDa isoform of glutamic acid decarboxylase.

scientific article

Increased expression of GAD65 and GABA in pancreatic beta-cells impairs first-phase insulin secretion.

scientific article published on September 2000

Islet cell and 64K autoantibodies are associated with plasma IgG in newly diagnosed insulin-dependent diabetic children

scientific article published on 01 December 1986

Islet cell antibodies-theoretical and practical implications

scientific article published on 01 November 1981

Islet transplantation in mice differing in the I and S subregions of the H-2 complex

scientific article published on 01 June 1981

Local GABA circuit control of experience-dependent plasticity in developing visual cortex.

scientific article

Membrane anchoring of the autoantigen GAD65 to microvesicles in pancreatic beta-cells by palmitoylation in the NH2-terminal domain ⬇️

scientific article published on July 1, 1992

Palmitoylation controls trafficking of GAD65 from Golgi membranes to axon-specific endosomes and a Rab5a-dependent pathway to presynaptic clusters.

scientific article published on 23 March 2004

Palmitoylation cycles and regulation of protein function (Review).

scientific article published on 30 January 2009

Pancreatic beta cells express two autoantigenic forms of glutamic acid decarboxylase, a 65-kDa hydrophilic form and a 64-kDa amphiphilic form which can be both membrane-bound and soluble

scientific article published on 01 December 1991

Primary Human and Rat β-Cells Release the Intracellular Autoantigens GAD65, IA-2, and Proinsulin in Exosomes Together With Cytokine-Induced Enhancers of Immunity.

scientific article published on 21 November 2016

Revelation of specificity of 64K autoantibodies in IDDM serums by high-resolution 2-D gel electrophoresis. Unambiguous identification of 64K target antigen

scientific article published on 01 September 1989

Rodent islet cell antigens recognized by antibodies in sera from diabetic patients

scientific article published on 01 January 1982

Studies of the isolation and viability of human islets of Langerhans

scientific article published on 01 May 1988

Sub-cellular fractionation of Trypanosoma brucei. Isolation and characterization of plasma membranes

scientific article published on 01 June 1980

The glutamate decarboxylase and 38KD autoantigens in type 1 diabetes: aspects of structure and epitope recognition.

scientific article

Transfer of type 1 (insulin-dependent) diabetes mellitus associated autoimmunity to mice with severe combined immunodeficiency (SCID)

scientific article published on 01 June 1993

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