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List of works by Ana Lluch

18F-fluoromisonidazole PET and Activity of Neoadjuvant Nintedanib in Early HER2-Negative Breast Cancer: A Window-of-Opportunity Randomized Trial.

scientific article published in September 2016

5-year analysis of neoadjuvant pertuzumab and trastuzumab in patients with locally advanced, inflammatory, or early-stage HER2-positive breast cancer (NeoSphere): a multicentre, open-label, phase 2 randomised trial.

scientific article published on 11 May 2016

A PAM50-Based Chemoendocrine Score for Hormone Receptor-Positive Breast Cancer with an Intermediate Risk of Relapse.

scientific article published on 30 November 2016

A customized pigmentation SNP array identifies a novel SNP associated with melanoma predisposition in the SLC45A2 gene.

scientific article

A definition for aggressive disease in patients with HER-2 negative metastatic breast cancer: an expert consensus of the Spanish Society of Medical Oncology (SEOM).

scientific article published on 16 November 2016

A genomic predictor of response and survival following taxane-anthracycline chemotherapy for invasive breast cancer.

scientific article

A randomized phase II trial of platinum salts in basal-like breast cancer patients in the neoadjuvant setting. Results from the GEICAM/2006-03, multicenter study ⬇️

scientific article published on October 9, 2012

Adjuvant Tamoxifen Plus Ovarian Function Suppression Versus Tamoxifen Alone in Premenopausal Women With Early Breast Cancer: Patient-Reported Outcomes in the Suppression of Ovarian Function Trial.

scientific article published on 28 March 2016

An evaluation of the impact of technical bias on the concordance rate between primary and recurrent tumors in breast cancer.

scientific article

Anthracycline cardiotoxicity in the elderly cancer patient: a SIOG expert position paper.

scientific article published on 18 October 2010

Aromatase activity and estradiol in human breast cancer: its relationship to estradiol and epidermal growth factor receptors and to tumor-node-metastasis staging

scientific article published on 01 March 1992

Associations between aromatase CYP19 rs10046 polymorphism and breast cancer risk: from a case-control to a meta-analysis of 20,098 subjects.

scientific article

Autocrine CCL5 effect mediates trastuzumab resistance by ERK pathway activation in HER2-positive breast cancer

scientific article published on 13 May 2020

Biweekly paclitaxel plus gemcitabine in advanced breast cancer: phase II trial and predictive value of HER2 extracellular domain.

scientific article published in February 2004

CA 15.3, CEA and TPA tumor markers in the early diagnosis of breast cancer relapse

scientific article published on 01 November 1994

CIP2A confirms its prognostic value in triple-negative breast cancer

scientific article published on 09 January 2017

Chemotherapy (CT) and hormonotherapy (HT) as neoadjuvant treatment in luminal breast cancer patients: results from the GEICAM/2006-03, a multicenter, randomized, phase-II study.

scientific article

Chromosomal abnormalities in women with breast cancer after autologous stem cell transplantation are infrequent and may not predict development of therapy-related leukemia or myelodysplastic syndrome

scientific article published on 01 June 2000

Circulating miR-99a-5p Expression in Plasma: A Potential Biomarker for Early Diagnosis of Breast Cancer

scientific article published on 08 October 2020

Clinical implications of routine genomic mutation sequencing in PIK3CA/AKT1 and KRAS/NRAS/BRAF in metastatic breast cancer.

scientific article published on 14 September 2016

Concordance of genomic alterations between primary and recurrent breast cancer.

scientific article

Correction to: Persistent major alopecia following adjuvant docetaxel for breast cancer: incidence, characteristics, and prevention with scalp cooling

scientific article published on 01 October 2018

Cost-utility analysis of nanoparticle albumin-bound paclitaxel versus paclitaxel in monotherapy in pretreated metastatic breast cancer in Spain.

scientific article published on 28 March 2013

Critically short telomeres and toxicity of chemotherapy in early breast cancer

scientific article

Current controversies in the management of early breast cancer.

scientific article published on June 2007

Defective cyclin B1 induction in trastuzumab-emtansine (T-DM1) acquired resistance in HER2-positive breast cancer.

scientific article published on 18 August 2017

Deficiency in p53 is required for doxorubicin induced transcriptional activation of NF-кB target genes in human breast cancer

scientific article published on January 2014

Deletion of chromosome 11q predicts response to anthracycline-based chemotherapy in early breast cancer

scientific article published on 01 January 2007

Deletion of the PER3 gene on chromosome 1p36 in recurrent ER-positive breast cancer

scientific article

Diagnosis and medical treatment of breast cancer. Cordoba Consensus of 2007.

scientific article published on September 2008

Doxorubicin and paclitaxel in advanced breast carcinoma: importance of prior adjuvant anthracycline therapy.

scientific article

Efficacy and safety of neoadjuvant pertuzumab and trastuzumab in women with locally advanced, inflammatory, or early HER2-positive breast cancer (NeoSphere): a randomised multicentre, open-label, phase 2 trial

scientific article

Emerging EGFR antagonists for breast cancer.

scientific article published on 15 May 2014

Enhanced MAF Oncogene Expression and Breast Cancer Bone Metastasis

scientific article

Epidermal growth factor in human breast cancer, endometrial carcinoma and lung cancer. Its relationship to epidermal growth factor receptor, estradiol receptor and tumor TNM

scientific article published on 01 April 1993

Epirubicin Plus Cyclophosphamide Followed by Docetaxel Versus Epirubicin Plus Docetaxel Followed by Capecitabine As Adjuvant Therapy for Node-Positive Early Breast Cancer: Results From the GEICAM/2003-10 Study

scientific article published on 28 September 2015

Estradiol receptors in combination with neu or myc oncogene amplifications might define new subtypes of breast cancer

scientific article published on 01 September 1994

Evaluating the Applicability of Data-Driven Dietary Patterns to Independent Samples with a Focus on Measurement Tools for Pattern Similarity

scientific article

Evaluation of a 30-gene paclitaxel, fluorouracil, doxorubicin, and cyclophosphamide chemotherapy response predictor in a multicenter randomized trial in breast cancer.

scientific article

Evaluation of international treatment guidelines and prognostic tests for the treatment of early breast cancer.

scientific article published on 14 October 2008

Evidence-based use of taxanes in the adjuvant setting of breast cancer. A review of randomized phase III trials.

scientific article published on 11 June 2007

Evolution of tumour biology upon progression. Do we know our enemy?

scientific article published on 01 June 2012

Final 10-year results of the Breast International Group 2-98 phase III trial and the role of Ki67 in predicting benefit of adjuvant docetaxel in patients with oestrogen receptor positive breast cancer.

scientific article

Finding the right dose of fulvestrant in breast cancer ⬇️

scientific article published on July 15, 2012

Fluorouracil, doxorubicin, and cyclophosphamide (FAC) versus FAC followed by weekly paclitaxel as adjuvant therapy for high-risk, node-negative breast cancer: results from the GEICAM/2003-02 study

scientific article published on 03 June 2013

FoxA and LIPG endothelial lipase control the uptake of extracellular lipids for breast cancer growth

scientific article published on 5 April 2016

Gemcitabine and capecitabine in previously anthracycline-treated metastatic breast cancer: a multicenter phase II study (SOLTI 0301 trial).

scientific article published on 25 November 2009

Gemcitabine in combination with doxorubicin in advanced breast cancer: final results of a phase II pharmacokinetic trial

scientific article published on 01 July 2000

Generation, characterization, and maintenance of trastuzumab-resistant HER2+ breast cancer cell lines

scientific article

Genetic variants in PARP1 (rs3219090) and IRF4 (rs12203592) genes associated with melanoma susceptibility in a Spanish population

scientific article

Genomic profile of breast cancer: cost-effectiveness analysis from the Spanish National Healthcare System perspective.

scientific article published on 12 September 2014

Germline mutations in CDKN2A are infrequent in female patients with melanoma and breast cancer.

scientific article published in August 2009

HDAC5 Inhibitors as a Potential Treatment in Breast Cancer Affecting Very Young Women

scientific article published on 10 February 2020

HRAS1 minisatellite alleles and breast cancer in Spanish women under age forty years. ⬇️

scientific article published on 12 March 2000

Heterogeneous lack of expression of the tumour suppressor PTEN protein in human neoplastic tissues

scientific article published on 01 January 2001

High ERK protein expression levels correlate with shorter survival in triple-negative breast cancer patients

scientific article

High Numbers of Circulating CD57+ NK Cells Associate with Resistance to HER2-Specific Therapeutic Antibodies in HER2+ Primary Breast Cancer

scientific article published on 12 June 2019

High Proliferation Predicts Pathological Complete Response to Neoadjuvant Chemotherapy in Early Breast Cancer

scientific article published on 19 January 2016

High Proliferation Predicts Pathological Complete Response to Neoadjuvant Chemotherapy in Early Breast Cancer

scientific article

High stability of microRNAs in tissue samples of compromised quality

scientific article published on 03 October 2013

Identification of candidate polymorphisms on stress oxidative and DNA damage repair genes related with clinical outcome in breast cancer patients.

scientific article published on 5 December 2012

Immune modulation of pathologic complete response after neoadjuvant HER2-directed therapies in the NeoSphere trial.

scientific article published on 19 September 2015

Impact of a mammography screening programme on the breast cancer population of the Region of Valencia (Spain).

scientific article published in November 2008

Implementation and assessment of a fast-track programme to improve communication between primary and specialized care in patients with suspected cancer: how to shorten time between initial symptoms of cancer, diagnosis and initiation of treatment

scientific article published on 07 August 2014

In response: Genomic profile of breast cancer

scientific article published on 22 March 2015

Integrating radical local treatment of the primary in the management of stage IV breast cancer. When is the best moment for the resection of the primary tumor?

scientific article published on 05 April 2012

Interleukin-6 concentration changes in plasma and saliva in bisphosphonate-related osteonecrosis of the jaws.

scientific article published on 10 July 2013

Intratumoral variation of estrogen and progesterone receptors in breast cancer: relationship with histopathological characteristics of the tumor.

scientific article published in January 1990

Intratumoral variations in cytoplasmic estrogen receptor levels in breast cancer

scientific article published on 01 January 1987

Intrinsic Subtypes and Gene Expression Profiles in Primary and Metastatic Breast Cancer.

scientific article

Involvement of Different networks in mammary gland involution after the pregnancy/lactation cycle: Implications in breast cancer.

scientific article published on 21 April 2015

Long telomere length and a TERT-CLPTM1 locus polymorphism association with melanoma risk.

scientific article published on 31 October 2014

Low number of examined lymph nodes in node-negative breast cancer patients is an adverse prognostic factor

scientific article published on 27 July 2006

Lower Breast Cancer Risk among Women following the World Cancer Research Fund and American Institute for Cancer Research Lifestyle Recommendations: EpiGEICAM Case-Control Study.

scientific article published on 15 May 2015

MC1R, SLC45A2 and TYR genetic variants involved in melanoma susceptibility in southern European populations: results from a meta-analysis.

scientific article published on 28 March 2012

MSK1 regulates luminal cell differentiation and metastatic dormancy in ER+ breast cancer

scientific article

MYC and MCL1 Cooperatively Promote Chemotherapy-Resistant Breast Cancer Stem Cells via Regulation of Mitochondrial Oxidative Phosphorylation

scientific article

Mechanism of suppression of the depressed lymphocyte response in lung cancer patients

scientific article published on 01 May 1985

MicroRNA Profile in Response to Doxorubicin Treatment in Breast Cancer

scientific article

MicroRNA profile in very young women with breast cancer

scientific article

Mobilization of peripheral blood progenitor cells with a combination of cyclophosphamide, r-metHuSCF and filgrastim in patients with breast cancer previously treated with chemotherapy

scientific article published on 01 February 2003

Molecular biology in breast cancer: intrinsic subtypes and signaling pathways.

scientific article published on 16 December 2011

Mutational analysis of BRCA1 and BRCA2 genes in Spanish women with early-onset breast cancer

scientific article published on 12 March 2000

NH(2)-terminal truncated HER-2 protein but not full-length receptor is associated with nodal metastasis in human breast cancer

scientific article published on 01 February 2002

NK Cell Infiltrates and HLA Class I Expression in Primary HER2+ Breast Cancer Predict and Uncouple Pathological Response and Disease-free Survival

scientific article published on 06 December 2018

Nab-Paclitaxel in Metastatic Breast Cancer: Defining the Best Patient Profile.

scientific article published on 17 August 2015

Neoadjuvant and adjuvant trastuzumab in patients with HER2-positive locally advanced breast cancer (NOAH): follow-up of a randomised controlled superiority trial with a parallel HER2-negative cohort

scientific article published on 20 March 2014

Nitration of cathepsin D enhances its proteolytic activity during mammary gland remodelling after lactation

scientific article published on 01 April 2009

Non-canonical NF-κB pathway activation predicts outcome in borderline oestrogen receptor positive breast carcinoma

scientific article published on 12 July 2016

Nonpegylated Liposomal Doxorubicin (TLC-D99), Paclitaxel, and Trastuzumab in HER-2-Overexpressing Breast Cancer: A Multicenter Phase I/II Study

scientific article published on 01 January 2009

Nuclear PARP-1 protein overexpression is associated with poor overall survival in early breast cancer ⬇️

scientific article published on September 9, 2011

Obesity and survival in operable breast cancer patients treated with adjuvant anthracyclines and taxanes according to pathological subtypes: a pooled analysis

scientific article

Outcome differences between patients with node-negative breast cancer classified according to the st. Gallen risk categories.

scientific article published in November 2009

PI3K pathway mutations and PTEN levels in primary and metastatic breast cancer.

scientific article

PP2A inhibition determines poor outcome and doxorubicin resistance in early breast cancer and its activation shows promising therapeutic effects

scientific article published on February 2015

Paclitaxel plus doxorubicin in metastatic breast cancer: preliminary analysis of cardiotoxicity

scientific article published on October 1, 1997

Paclitaxel plus vinorelbine: an active regimen in metastatic breast cancer patients with prior anthracycline exposure.

scientific article published on January 2000

Parotid gland metastasis of a breast cancer

scientific article published on 01 April 2007

Pathological complete response rates following different neoadjuvant chemotherapy regimens for operable breast cancer according to ER status, in two parallel, randomized phase II trials with an adaptive study design (ECTO II)

article

Patterns of HER2 Gene Amplification and Response to Anti-HER2 Therapies

scientific article published on 15 June 2015

Persistent major alopecia following adjuvant docetaxel for breast cancer: incidence, characteristics, and prevention with scalp cooling

scientific article published on 19 June 2018

Pertuzumab monotherapy after trastuzumab-based treatment and subsequent reintroduction of trastuzumab: activity and tolerability in patients with advanced human epidermal growth factor receptor 2-positive breast cancer.

scientific article

Phase I study of oral vinorelbine and capecitabine in patients with metastatic breast cancer.

scientific article published on June 2010

Phase II Clinical Trial of Ixabepilone (BMS-247550), an Epothilone B Analog, in Patients With Taxane-Resistant Metastatic Breast Cancer

scientific article published on 02 July 2007

Phase II and tumor pharmacodynamic study of gefitinib in patients with advanced breast cancer.

scientific article published on 6 June 2005

Phase II study of pemetrexed in breast cancer patients pretreated with anthracyclines.

scientific article

Phase II trial of cisplatin and etoposide as first-line therapy in metastatic breast carcinoma

scientific article published on 01 July 1994

Phase II trial of weekly IV vinorelbine in first-line advanced breast cancer chemotherapy

scientific article published on 01 November 1994

Phase III trial evaluating the addition of paclitaxel to doxorubicin followed by cyclophosphamide, methotrexate, and fluorouracil, as adjuvant or primary systemic therapy: European Cooperative Trial in Operable Breast Cancer.

scientific article published on 30 March 2009

Poly (ADP-ribose) polymerase inhibition enhances trastuzumab antitumour activity in HER2 overexpressing breast cancer.

scientific article published on 12 August 2014

Pooled analysis of prospective European studies assessing the impact of using the 21-gene Recurrence Score assay on clinical decision making in women with oestrogen receptor-positive, human epidermal growth factor receptor 2-negative early-stage bre

scientific article published on 18 August 2016

Predicting response and survival in chemotherapy-treated triple-negative breast cancer.

scientific article

Prognostic Impact of Phosphorylated HER-2 in HER-2+ Primary Breast Cancer ⬇️

scientific article published on June 28, 2011

Prognostic factors in patients with isolated recurrences of breast cancer (stage IV-NED)

scientific article published on 01 January 1999

Prognostic factors predicting survival from first recurrence in patients with metastatic breast cancer: analysis of 439 patients

scientific article published on 01 July 1999

Prognostic significance of c-erbB-2/neu amplification and epidermal growth factor receptor (EGFR) in primary breast cancer and their relation to estradiol receptor (ER) status

scientific article published on 01 June 1997

Prognostic significance of the immunocytochemical detection of contaminating tumor cells (CTC) in apheresis products of patients with high-risk breast cancer treated with high-dose chemotherapy and stem cell transplantation

scientific article published on 01 February 2001

Progress against solid tumors in danger: the metastatic breast cancer example

scientific article published on 27 August 2012

Prospective transGEICAM study of the impact of the 21-gene Recurrence Score assay and traditional clinicopathological factors on adjuvant clinical decision making in women with estrogen receptor-positive (ER+) node-negative breast cancer.

scientific article

Quality Indicators to Assure and Improve Cancer Care in Spain Using the Delphi Technique

scientific article published on May 2016

Quantitative monoclonal antibody determination of estrogen and progesterone receptors in human breast cancer: correlation with the radioligand method

scientific article published on 01 September 1994

Randomized phase III trial of pegylated liposomal doxorubicin versus vinorelbine or mitomycin C plus vinblastine in women with taxane-refractory advanced breast cancer.

scientific article published in October 2004

Randomized, double-blind, multicenter trial comparing two doses of arzoxifene (LY353381) in hormone-sensitive advanced or metastatic breast cancer patients.

scientific article

Randomized, placebo-controlled, double-blind, phase II study of axitinib plus docetaxel versus docetaxel plus placebo in patients with metastatic breast cancer.

scientific article published on 9 May 2011

Recent Insights into the Development of Preclinical Trastuzumab-Resistant HER2+ Breast Cancer Models

scientific article published on 16 December 2016

Recommendations for the prevention, diagnosis, and treatment of osteonecrosis of the jaw (ONJ) in cancer patients treated with bisphosphonates.

scientific article published on August 2007

Removal of primary tumor improves survival in metastatic breast cancer. Does timing of surgery influence outcomes?

scientific article published on 03 August 2011

Retrospective analysis of the use of G-CSF and its impact on dose response for anthracycline plus taxane-based schedules in early breast cancer

scientific article

Role of MTHFR (677, 1298) haplotype in the risk of developing secondary leukemia after treatment of breast cancer and hematological malignancies

scientific article published on 03 May 2007

Role of glutathione S-transferases in melanoma susceptibility: association with GSTP1 rs1695 polymorphism.

scientific article published on 4 April 2012

SOLTI (Solid Tumor Intensification) Group experience with high-dose chemotherapy treatment for early breast carcinoma

Snail1-expressing fibroblasts in the tumor microenvironment display mechanical properties that support metastasis

scientific article published on 08 December 2014

Spanish Mediterranean diet and other dietary patterns and breast cancer risk: case-control EpiGEICAM study

scientific article

Standard versus continuous administration of capecitabine in metastatic breast cancer (GEICAM/2009-05): a randomized, noninferiority phase II trial with a pharmacogenetic analysis

scientific article

Sunitinib in combination with trastuzumab for the treatment of advanced breast cancer: activity and safety results from a phase II study

scientific article

Supportive care for patients with early breast cancer.

scientific article published on January 2010

Surgery following neoadjuvant therapy in patients with HER2-positive locally advanced or inflammatory breast cancer participating in the NeOAdjuvant Herceptin (NOAH) study.

scientific article published on 16 August 2011

The "El Alamo" project (1990-1997): two consecutive hospital-based studies of breast cancer outcomes in Spain

scientific article published on 01 July 2006

The Antitumor Effect of Metformin Is Mediated by miR-26a in Breast Cancer

scientific article published on 10 August 2016

The effect of body mass index on overall and disease-free survival in node-positive breast cancer patients treated with docetaxel and doxorubicin-containing adjuvant chemotherapy: the experience of the BIG 02-98 trial

scientific article published in January 2010

The miRNA-449 family mediates doxorubicin resistance in triple-negative breast cancer by regulating cell cycle factors

scientific article published on 29 March 2019

The role of miR-26a and miR-30b in HER2+ breast cancer trastuzumab resistance and regulation of the CCNE2 gene

scientific article published on 25 January 2017

The single-nucleotide polymorphisms +936 C/T VEGF and -710 C/T VEGFR1 are associated with breast cancer protection in a Spanish population.

scientific article published in June 2012

The use of taxanes in the neoadjuvant treatment of breast cancer: a review of randomized phase II/III trials.

scientific article published on October 2007

Time-to-progression in breast cancer: a stratification model for clinical trials.

scientific article published on 26 November 2007

Trastuzumab in small tumours and in elderly women.

scientific article published on 06 May 2013

Trastuzumab or lapatinib with standard chemotherapy for HER2-positive breast cancer: results from the GEICAM/2006-14 trial.

scientific article published on 23 January 2014

Treatment innovations for metastatic breast cancer: nanoparticle albumin-bound (NAB) technology targeted to tumors.

scientific article published on 21 August 2013

Treatment of HER2 positive advanced breast cancer with T-DM1: A review of the literature.

scientific article published on 11 August 2015

Treatment with a nonanthracycline regimen in advanced breast cancer: vinorelbine, cyclophosphamide, and 5-fluorouracil with folinic acid

scientific article published on 01 April 1999

Triple-negative breast cancer: molecular features, pathogenesis, treatment and current lines of research.

scientific article published on 08 January 2010

Tumor-Associated Fibroblasts Promote HER2-Targeted Therapy Resistance through FGFR2 Activation

scientific article published on 07 November 2019

Twelve-Month Estrogen Levels in Premenopausal Women With Hormone Receptor-Positive Breast Cancer Receiving Adjuvant Triptorelin Plus Exemestane or Tamoxifen in the Suppression of Ovarian Function Trial (SOFT): The SOFT-EST Substudy

scientific article published on 4 January 2016

Value of CA 15.3 in breast cancer and comparison with CEA and TPA: a study of specificity in disease-free follow-up patients and sensitivity in patients at diagnosis of the first metastasis

scientific article published on 01 January 1996

Zoledronic acid in the treatment of metastatic breast cancer

scientific article published on January 2014

[Conventional and aggressive chemo-radiotherapy of chronic granulocytic leukemia in its different phases. Other therapeutic problems]

scientific article published on 01 January 1984

[Epidemiological study of the GEICAM group about breast cancer in Spain (1990-1993): El Alamo project]

scientific article published on 01 January 2004

[Estrogen and progesterone receptors in cancer of the breast]

scientific article published on 01 October 1987

[High-dosage chemotherapy and autologous transplant of hematopoietic germ cells from peripheral blood in high-risk recurrence carcinoma of the breast (with >= or 10 involved axillary nodes at diagnosis) Preliminary results of the Solti 9301 cooperat

scientific article published on 01 April 1997

[Multicentric prospective, randomized study of the role of filgrastim (G-CSF) after transplant of hematopoietic progenitor cells mobilized with G-CSF in patients with cancer of the breast]

scientific article published on 01 April 1997

[Neoadjuvant therapy for operable breast-cancer]

scientific article published on 01 March 2006

[Toxicity and hematopoietic regeneration produced by adjuvant chemotherapy in patients with neoplasia of the breast]

scientific article published on 01 June 1988

[Treatment of locally advanced cancer of the breast]

scientific article published on 01 May 1987

c-Jun N-Terminal Kinase Inactivation by Mitogen-Activated Protein Kinase Phosphatase 1 Determines Resistance to Taxanes and Anthracyclines in Breast Cancer.

scientific article published on 06 September 2016

rs12512631 on the group specific complement (vitamin D-binding protein GC) implicated in melanoma susceptibility.

scientific article published on 27 March 2013

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