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List of works by Jose Manuel Sanchez Ruiz

A Fourier-transform infrared spectroscopic study of the phosphoserine residues in hen egg phosvitin and ovalbumin

scientific article published on 01 May 1988

A designed protein as experimental model of primordial folding

scientific article

A model-independent, nonlinear extrapolation procedure for the characterization of protein folding energetics from solvent-denaturation data.

scientific article published on November 1996

A simple tool to explore the distance distribution of correlated mutations in proteins.

scientific article published on 18 October 2005

A stability pattern of protein hydrophobic mutations that reflects evolutionary structural optimization.

scientific article published on 12 August 2005

An osmolyte effect on the heat capacity change for protein folding.

scientific article published in July 1995

Analysis of differential scanning calorimetry data for proteins. Criteria of validity of one-step mechanism of irreversible protein denaturation.

scientific article

Analysis of the thermal unfolding of porcine procarboxypeptidase A and its functional pieces by differential scnning calorimetry

scientific article published on 01 September 1988

Are Protein Folding Intermediates the Evolutionary Consequence of Functional Constraints?

scientific article published on 07 January 2015

Are there equilibrium intermediate states in the urea-induced unfolding of hen egg-white lysozyme?

scientific article published on 01 August 1997

Between-species variation in the kinetic stability of TIM proteins linked to solvation-barrier free energies.

scientific article published on 28 October 2008

Beyond Lumry-Eyring: An unexpected pattern of operational reversibility/irreversibility in protein denaturation

scientific article published on 01 January 2008

Cold denaturation of ubiquitin

scientific article published on 01 January 1999

Comparative calorimetric study of non-amyloidogenic and amyloidogenic variants of the homotetrameric protein transthyretin

scientific article published on 01 December 2000

Differential scanning calorimetric study of carboxypeptidase B, procarboxypeptidase B and its globular activation domain

scientific article published on 01 September 1991

Differential scanning calorimetry of lobster haemocyanin

scientific article published on 01 February 1990

Differential scanning calorimetry of the irreversible thermal denaturation of thermolysin ⬇️

scientific article published on March 8, 1988

Direct Measurement of Barrier Heights in Protein Folding

scientific article published on 01 December 2005

Dissecting structural and electrostatic interactions of charged groups in alpha-sarcin. An NMR study of some mutants involving the catalytic residues.

scientific article published in November 2003

Diversity of chemical mechanisms in thioredoxin catalysis revealed by single-molecule force spectroscopy.

scientific article published on 13 July 2009

Do proteins always benefit from a stability increase? Relevant and residual stabilisation in a three-state protein by charge optimisation

scientific article published on 01 November 2004

Dwell time analysis of a single-molecule mechanochemical reaction.

scientific article

Electrostatic interactions in ubiquitin: stabilization of carboxylates by lysine amino groups.

scientific article

Energetic and structural consequences of desolvation/solvation barriers to protein folding/unfolding assessed from experimental unfolding rates

scientific article

Energetic evidence for formation of a pH-dependent hydrophobic cluster in the denatured state of Thermus thermophilus ribonuclease H.

scientific article

Energetics of heparin binding to human acidic fibroblast growth factor.

scientific article published in December 2002

Engineering proteins with tunable thermodynamic and kinetic stabilities.

scientific article published in April 2008

Estimation of protein folding free energy barriers from calorimetric data by multi-model Bayesian analysis.

scientific article published on 19 July 2011

Evolution of conformational dynamics determines the conversion of a promiscuous generalist into a specialist enzyme.

scientific article

Exploring protein-folding ensembles: a variable-barrier model for the analysis of equilibrium unfolding experiments.

scientific article

Heat capacity analysis of oxidized Escherichia coli thioredoxin fragments (1--73, 74--108) and their noncovalent complex. Evidence for the burial of apolar surface in protein unfolded states

scientific article published on 01 March 2001

Heme-binding enables allosteric modulation in an ancient TIM-barrel glycosidase

scientific article published on 15 January 2021

How many ionizable groups can sit on a protein hydrophobic core?

scientific article

Human cystathionine β-synthase (CBS) contains two classes of binding sites for S-adenosylmethionine (SAM): complex regulation of CBS activity and stability by SAM

scientific article

Hyperstability and substrate promiscuity in laboratory resurrections of Precambrian β-lactamases

scientific article

Ionization state of the coenzyme 5'-phosphate ester in cytosolic aspartate aminotransferase. A Fourier transform infrared spectroscopic study

scientific article published on 01 May 1986

L-phenylalanine binding and domain organization in human phenylalanine hydroxylase: a differential scanning calorimetry study.

scientific article

Large-scale modulation of thermodynamic protein folding barriers linked to electrostatics

scholarly article

Ligand effects on protein thermodynamic stability.

scientific article published on 14 June 2006

Maximum entropy, analysis of kinetic processes involving chemical and folding-unfolding changes in proteins

scientific article published on 01 January 1997

Mechanism of Protein Kinetic Stabilization by Engineered Disulfide Crosslinks

scientific article

Modulation of buried ionizable groups in proteins with engineered surface charge.

scientific article

Molecular determinants of expansivity of native globular proteins: a pressure perturbation calorimetry study.

scientific article published on 2 June 2014

Mutational studies on resurrected ancestral proteins reveal conservation of site-specific amino acid preferences throughout evolutionary history

scientific article

Native hydrogen bonds in a molten globule: the apoflavodoxin thermal intermediate

scientific article published on 01 March 2001

Phenotypic comparisons of consensus variants versus laboratory resurrections of Precambrian proteins

scientific article

Probing free-energy surfaces with differential scanning calorimetry.

scientific article published on January 2011

Probing the Mutational Interplay between Primary and Promiscuous Protein Functions: A Computational-Experimental Approach ⬇️

scientific article published on June 14, 2012

Protein kinetic stability.

scientific article published on 11 February 2010

Protein-protein interactions at an enzyme-substrate interface: characterization of transient reaction intermediates throughout a full catalytic cycle of Escherichia coli thioredoxin reductase.

scientific article published in January 2010

Relation between protein stability, evolution and structure, as probed by carboxylic acid mutations.

scientific article published in February 2004

Robustness of downhill folding: guidelines for the analysis of equilibrium folding experiments on small proteins.

scientific article published in May 2005

Role of conservative mutations in protein multi-property adaptation

scientific article

Role of low native state kinetic stability and interaction of partially unfolded states with molecular chaperones in the mitochondrial protein mistargeting associated with primary hyperoxaluria ⬇️

scientific article published on November 20, 2010

Role of residual structure in the unfolded state of a thermophilic protein.

scientific article

Role of solvation barriers in protein kinetic stability.

scientific article published on 19 May 2006

Single-molecule paleoenzymology probes the chemistry of resurrected enzymes

scientific article (publication date: May 2011)

The consensus-based approach for gene/enzyme replacement therapies and crystallization strategies: the case of human alanine-glyoxylate aminotransferase

scientific article

The effect of charge-introduction mutations on E. coli thioredoxin stability.

scientific article

The ionization states of the 5'-phosphate group in the various coenzyme forms bound to mitochondrial aspartate aminotransferase

scientific article published on 01 April 1991

The molecular basis of cooperativity in protein folding. Thermodynamic dissection of interdomain interactions in phosphoglycerate kinase

scientific article published on 01 January 1992

Thermal versus guanidine-induced unfolding of ubiquitin. An analysis in terms of the contributions from charge-charge interactions to protein stability

scientific article published on 01 June 1999

Thermodynamic and kinetic characterization of a germ line human lambda6 light-chain protein: the relation between unfolding and fibrillogenesis.

scientific article published on 6 January 2009

Thermostable and promiscuous Precambrian proteins

scientific article published on 01 June 2014

pH corrections in chemical denaturant solutions.

scientific article

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