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List of works by Marlene Belfort

157 Identification of intein inhibitors as novel anti-microbials with relevance to tuberculosis

1H, 13C, and 15N NMR assignments of an engineered intein based on Mycobacterium tuberculosis RecA.

scientific article published on 30 May 2008

24 Evolutionary dynamics of inteins in bacteria

4981791 RNA stabilization vector

scientific article published in 1991

A bacterial group II intron favors retrotransposition into plasmid targets

scientific article

A conserved threonine spring-loads precursor for intein splicing

scientific article

A decades-long journey with mobile introns

scientific article published on April 2015

A genetic system yields self-cleaving inteins for bioseparations

scientific article published on 01 September 1999

A mutant screen reveals RNase E as a silencer of group II intron retromobility in Escherichia coli

scientific article

A nomenclature for restriction enzymes, DNA methyltransferases, homing endonucleases and their genes

scientific article

A redox trap to augment the intein toolbox.

scientific article published on 17 January 2013

A single functional arginyl residue involved in the catalysis promoted by Lactobacillus casei thymidylate synthetase

scientific article published on 01 October 1980

A site-specific endonuclease and co-conversion of flanking exons associated with the mobile td intron of phage T4.

scientific article

A site-specific endonuclease encoded by a typical archaeal intron

scientific article

Activation of the lambda int gene by the cII and cIII gene products

article

An analysis of the processes of infection and induction of E. coli mutant hfl-l by bacteriophage lambda

scientific article published on 01 September 1973

An open letter to Elias Zerhouni

scientific article published on 01 March 2005

Analysis of the LAGLIDADG interface of the monomeric homing endonuclease I-DmoI.

scientific article

Application of the microwave oven to scale-up in biological temperatures-shift experiments

Back to Basics: Structure, Function, Evolution and Application of Homing Endonucleases and Inteins

Backbone assignments of mini-RecA intein with short native exteins and an active N-terminal catalytic cysteine.

scientific article

Backbone dynamics and global effects of an activating mutation in minimized Mtu RecA inteins

scientific article

Bacterial group II intron genomic neighborhoods reflect survival strategies: hiding and hijacking

scientific article published on 05 March 2020

Bipolar localization of the group II intron Ll.LtrB is maintained in Escherichia coli deficient in nucleoid condensation, chromosome partitioning and DNA replication.

scientific article

Branching out of the intein active site in protein splicing

scientific article

Catalytic domain structure and hypothesis for function of GIY-YIG intron endonuclease I-TevI

scientific article

Characterization of the intron in the phage T4 thymidylate synthase gene and evidence for its self-excision from the primary transcript

scientific article published in April 1986

Cisplatin inhibits protein splicing, suggesting inteins as therapeutic targets in mycobacteria.

scientific article

Cisplatin protects mice from challenge of by targeting the Prp8 intein

scientific article published in 2019

Cloning and expression of an intron-deleted phage T4 td gene

scientific article published in October 1986

Coincidence of cleavage sites of intron endonuclease I-TevI and critical sequences of the host thymidylate synthase gene.

scientific article

Conditional DnaB Protein Splicing Is Reversibly Inhibited by Zinc in Mycobacteria

scientific article published on 14 July 2020

Conditional Protein Splicing Switch in Hyperthermophiles through an Intein-Extein Partnership.

scientific article published on 30 January 2018

Configuration of the catalytic GIY-YIG domain of intron endonuclease I-TevI: coincidence of computational and molecular findings

scientific article published on May 1999

Corrigendum to: Bacterial Group II Intron Genomic Neighborhoods Reflect Survival Strategies: Hiding and Hijacking

scientific article published on 04 September 2020

Crystallographic and Mutational Studies of Mycobacterium tuberculosis recA Mini-inteins Suggest a Pivotal Role for a Highly Conserved Aspartate Residue

scientific article

Deletion-tolerance and trans-splicing of the bacteriophage T4 td intron

scientific article published on 01 February 1990

Distance determination by GIY-YIG intron endonucleases: discrimination between repression and cleavage functions

scientific article published on 31 March 2006

Domain structure and RNA annealing activity of the Escherichia coli regulatory protein StpA ⬇️

scientific article published on May 1, 1998

Domain structure and three-dimensional model of a group II intron-encoded reverse transcriptase

scientific article

Efficient suppression of the requirement for N function of bacteriophage lambda by a Rho-defective E.coli suA mutant.

scientific article published on October 1976

Electronic structure of neighboring extein residue modulates intein C-terminal cleavage activity

scientific article

Enigmatic distribution, evolution, and function of inteins

scientific article

Erratum: Retrotransposition of a bacterial group II intron

scientific article published in Nature

Erratum: correction: Retrotransposition of a bacterial group II intron

scientific article published in Nature

Escherichia coli protein StpA stimulates self-splicing by promoting RNA assembly in vitro.

scientific article published in October 1995

Exon and protein positioning in a pre-catalytic group II intron RNP primed for splicing

scientific article published on 06 October 2020

Exploring Intein Inhibition by Platinum Compounds as an Antimicrobial Strategy

scientific article published on 8 September 2016

Forks in the tracks: Group II introns, spliceosomes, telomeres and beyond

scientific article published on 11 October 2016

From monomeric to homodimeric endonucleases and back: engineering novel specificity of LAGLIDADG enzymes

scientific article published on 12 July 2006

Functional defects in transfer RNAs lead to the accumulation of ribosomal RNA precursors.

scientific article published on 9 February 2007

Förster resonance energy transfer-based cholesterolysis assay identifies a novel hedgehog inhibitor.

scientific article published on 18 June 2015

Genes within genes: independent expression of phage T4 intron open reading frames and the genes in which they reside

scientific article published in December 1988

Genetic and molecular analysis of RNA splicing in Escherichia coli

scientific article published on 01 January 1990

Genetic definition of a protein-splicing domain: functional mini-inteins support structure predictions and a model for intein evolution

scientific article published on October 1997

Global regulators orchestrate group II intron retromobility

scientific article published on April 2009

Group II Intron RNPs and Reverse Transcriptases: From Retroelements to Research Tools

scientific article published on 01 April 2019

Group II intron as cold sensor for self-preservation and bacterial conjugation

scientific article published on 07 May 2020

Group II intron inhibits conjugative relaxase expression in bacteria by mRNA targeting.

scientific article published on 15 June 2018

Group II intron-ribosome association protects intron RNA from degradation

scientific article published on 17 September 2013

Hand-holding for retrohoming in a molecular diversity dance

scientific article published on February 2013

Highly conserved histidine plays a dual catalytic role in protein splicing: a pKa shift mechanism

scientific article published on August 2009

Homing Endonuclease I-TevI: An Atypical Zinc Finger with a Novel Function

Homing endonuclease I-TevIII: dimerization as a means to a double-strand break

scientific article published on 8 February 2007

Homing endonucleases: from genetic anomalies to programmable genomic clippers

scientific article published on January 2014

Homing endonucleases: keeping the house in order

scientific article

Homing sweet homing: mobile introns in bacterial viruses

Importance of a Single Base Pair for Discrimination between Intron-Containing and Intronless Alleles by Endonuclease I-BmoI

scientific article published on 01 May 2003

Intein Clustering Suggests Functional Importance in Different Domains of Life

scientific article published on 25 November 2015

Intein-mediated purification of cytotoxic endonuclease I-TevI by insertional inactivation and pH-controllable splicing

scientific article

Inteins

scientific article published in March 2017

Interaction between conjugative and retrotransposable elements in horizontal gene transfer

scientific article

Interaction of cII, cIII, and cro gene products in the regulation of early and late functions of phage lambda

scientific article published in June 1977

Interdisciplinary bacteria and phages

scientific article published on 16 October 2008

Intertwined structure of the DNA-binding domain of intron endonuclease I-TevI with its substrate.

scientific article

Intron mobility in the T-even phages: high frequency inheritance of group I introns promoted by intron open reading frames.

scientific article published in February 1989

Intron-encoded Endonuclease I-TevII Binds Across the Minor Groove and Induces Two Distinct Conformational Changes in its DNA Substrate

scientific article published on 01 January 1996

Intron-encoded homing endonuclease I-TevI also functions as a transcriptional autorepressor

scientific article

Isolation, characterization and deletion mapping of amber mutations in the cII gene of phage λ

article

Learning to live together: mutualism between self-splicing introns and their hosts

scientific article

Lightning strikes twice: intron-intein coincidence

scientific article

Localization, mobility and fidelity of retrotransposed Group II introns in rRNA genes

scientific article

Mapping homing endonuclease cleavage sites using in vitro generated protein.

scientific article

Mechanism of Single-Stranded DNA Activation of Recombinase Intein Splicing

scientific article published on 23 July 2019

Mechanisms of intron mobility.

scientific article published on December 1995

Meeting report: mobile genetic elements and genome plasticity 2018.

scientific article

Methylation of rRNA as a host defense against rampant group II intron retrotransposition

scientific article published on 07 March 2021

Minimization and stabilization of the Mycobacterium tuberculosis recA intein

scientific article

Mobile Bacterial Group II Introns at the Crux of Eukaryotic Evolution

scientific article

Mobile DNA elements in T4 and related phages.

scientific article published on 28 October 2010

Mobile DNA: an evolving field

scientific article published on 5 June 2014

Mobile Group II Introns as Ancestral Eukaryotic Elements

scientific article published on 14 August 2017

Mobile Introns: Pathways and Proteins

Mobile self-splicing introns and inteins as environmental sensors

scientific article published on 5 May 2017

Modulation of intein activity by its neighboring extein substrates

scientific article published on 17 June 2009

Multiple self-splicing introns in bacteriophage T4: evidence from autocatalytic GTP labeling of RNA in vitro

scientific article published in October 1986

Multiple small RNAs identified in Mycobacterium bovis BCG are also expressed in Mycobacterium tuberculosis and Mycobacterium smegmatis

scientific article

Mycobacterial DnaB helicase intein as oxidative stress sensor

scientific article published in Nature Communications

Mycobacteriophages as Incubators for Intein Dissemination and Evolution

scientific article published on 04 October 2016

Nuclear expression of a group II intron is consistent with spliceosomal intron ancestry.

scientific article

Nucleotide sequence of a newly-identified Escherichia coli gene, stpA, encoding an H-NS-like protein.

scientific article published on December 1992

Oriented covalent immobilization of antibodies for measurement of intermolecular binding forces between zipper-like contact surfaces of split inteins

scientific article published on 31 May 2013

PREFACE

Post-translational environmental switch of RadA activity by extein-intein interactions in protein splicing

scientific article published on 22 June 2015

Probing the infra-structure of thymidylate synthase and deoxycytidylate deaminase

scientific article published on 01 January 1984

Processing of the intron-containing thymidylate synthase (td) gene of phage T4 is at the RNA level

scientific article

Protease activation of split green fluorescent protein

scientific article

Protein splicing of a recombinase intein induced by ssDNA and DNA damage

scientific article published on 28 December 2016

Quaternary arrangement of an active, native group II intron ribonucleoprotein complex revealed by small-angle X-ray scattering

scientific article published on 24 February 2014

RNA splicing and in vivo expression of the intron-containing td gene of bacteriophage T4.

scientific article published in January 1986

RNA-RNA interactions and pre-mRNA mislocalization as drivers of group II intron loss from nuclear genomes

scientific article

Recruitment of host functions suggests a repair pathway for late steps in group II intron retrohoming

scientific article published on October 2005

Redox-responsive zinc finger fidelity switch in homing endonuclease and intron promiscuity in oxidative stress

scientific article

Repressor and int synthesis of bacteriophage λ in the E. coli host mutant ER437 ⬇️

scientific article published on October 24, 1977

Retrohoming of a Bacterial Group II Intron

Retrohoming: cDNA-mediated mobility of group II introns requires a catalytic RNA.

scientific article published on January 1996

Retrotransposition of the Ll.LtrB group II intron proceeds predominantly via reverse splicing into DNA targets

scientific article published in December 2002

Retrotransposition strategies of the Lactococcus lactis Ll.LtrB group II intron are dictated by host identity and cellular environment.

scientific article

Riboregulation by DsrA RNA: trans-actions for global economy

scientific article (publication date: November 2000)

Riboregulation in Escherichia coli: DsrA RNA acts by RNA:RNA interactions at multiple loci

scientific article

Role of the interdomain linker in distance determination for remote cleavage by homing endonuclease I-TevI.

scientific article

Scientific serendipity initiates an intron odyssey.

scientific article published on 26 August 2009

SegG endonuclease promotes marker exclusion and mediates co-conversion from a distant cleavage site

scientific article published on November 2003

Selection and Structure of Hyperactive Inteins: Peripheral Changes Relayed to the Catalytic Center

scientific article

Selection of a Remote Cleavage Site by I-TevI, thetdIntron-encoded Endonuclease

Single-step affinity purification of toxic and non-toxic proteins on a fluidics platform

scientific article published on 25 January 2005

Social networking between mobile introns and their host genes

scientific article published on October 2010

Spliceosomal Prp8 intein at the crossroads of protein and RNA splicing

scientific article published on 10 October 2019

Spontaneous Proton Transfer to a Conserved Intein Residue Determines On-Pathway Protein Splicing ⬇️

scientific article published on December 23, 2010

Spontaneous shuffling of domains between introns of phage T4.

scientific article published on July 1990

Structural accommodations accompanying splicing of a group II intron RNP

scientific article published on 01 September 2018

Structure of a group II intron in complex with its reverse transcriptase

scientific article

Structure of an engineered intein reveals thiazoline ring and provides mechanistic insight

scientific article published on 08 January 2019

Structure of catalytically competent intein caught in a redox trap with functional and evolutionary implications

scientific article

SufB intein of Mycobacterium tuberculosis as a sensor for oxidative and nitrosative stresses

scientific article

Telomerase and retrotransposons: reverse transcriptases that shaped genomes

scientific article published on December 2011

The beginning of the end: links between ancient retroelements and modern telomerases

scholarly article

The cII-independent expression of the phage λ int gene in RNase III-defective E. coli ⬇️

scientific article published on October 1, 1980

The dynamic intein landscape of eukaryotes

scientific article published on 24 January 2018

The group II intron ribonucleoprotein precursor is a large, loosely packed structure

scientific article

The requirement of nonsense suppression for the development of several phages ⬇️

scientific article published on February 26, 1979

The small noncoding DsrA RNA is an acid resistance regulator in Escherichia coli

scientific article

The take and give between retrotransposable elements and their hosts

scientific article

The td intron endonuclease I-TevI makes extensive sequence-tolerant contacts across the minor groove of its DNA target.

scientific article published in October 1993

The win-win potential for motherhood and science

scientific article published on 01 January 2001

Two domains for splicing in the intron of the phage T4 thymidylate synthase (td) gene established by nondirected mutagenesis

article

Two for the price of one: a bifunctional intron-encoded DNA endonuclease-RNA maturase.

scientific article published on December 2003

Two-domain structure of the td intron-encoded endonuclease I-TevI correlates with the two-domain configuration of the homing site

article by V Derbyshire et al published January 1997 in Journal of Molecular Biology

Visualization of a group II intron in the 23S rRNA of a stable ribosome

scholarly article

Zinc finger as distance determinant in the flexible linker of intron endonuclease I-TevI.

scientific article

¹H, ¹³C and ¹⁵N NMR assignments of a Drosophila Hedgehog autoprocessing domain

scientific article published on 14 June 2013

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