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List of works by Alan-J. Cross

3H-Flupenthixol binding in post-mortem brains of schizophrenics: evidence for a selective increase in dopamine D2 receptors

scientific article published on 01 January 1981

3H-Mianserin binding in calf caudate: possible involvement of serotonin receptors in anti-depressant drug action

scientific article published on 01 October 1980

A behavioural and neurochemical study in rats of the pharmacology of loreclezole, a novel allosteric modulator of the GABAA receptor

scientific article published on 01 January 1996

A comparison of [3H]MK-801 and N-[1-(2-thienyl)cyclohexyl]-3,4-[3H]piperidine binding to the N-methyl-D-aspartate receptor complex in human brain.

scientific article published in April 1991

A human-specific AS3MT isoform and BORCS7 are molecular risk factors in the 10q24.32 schizophrenia-associated locus.

scientific article published on 9 May 2016

A randomized, placebo-controlled pilot trial of the delta opioid receptor agonist AZD2327 in anxious depression.

scientific article published on 04 January 2016

AZD6280, a novel partial γ-aminobutyric acid A receptor modulator, demonstrates a pharmacodynamically selective effect profile in healthy male volunteers.

scientific article published in February 2015

AZD8529, a positive allosteric modulator at the mGluR2 receptor, does not improve symptoms in schizophrenia: A proof of principle study.

scientific article published on 24 February 2016

Advancing drug discovery for neuropsychiatric disorders using patient-specific stem cell models

scientific article published on 27 January 2016

Altered expression of histamine signaling genes in autism spectrum disorder

scientific article published on 9 May 2017

Alzheimer's disease research and development: a call for a new research roadmap

scientific article published on April 2014

An autoradiographic analysis of serotonin receptors in human temporal cortex: Changes in Alzheimer-type dementia.

scientific article published in January 1988

Animal models of acute ischaemic stroke: can they predict clinically successful neuroprotective drugs? ⬇️

scientific article published on April 1, 1995

Antiparkinson potential of delta-opioid receptor agonists.

scientific article

Attenuation by chlormethiazole of oedema following focal ischaemia in the cerebral cortex of the rat.

scientific article published in May 1994

Attenuation of nicotine-taking and nicotine-seeking behavior by the mGlu2 receptor positive allosteric modulators AZD8418 and AZD8529 in rats.

scientific article

Autoradiographic localization of delta opiate receptors in rat and human brain

scientific article published on 01 November 1988

Behavioural and biochemical effects of chronic amphetamine treatment in the vervet monkey ⬇️

scientific article published on January 1, 1982

Behavioural and biochemical effects of chronic treatment with amphetamine in the vervet monkey

scientific article published on 01 April 1983

Brain serotonin receptors in Huntington's disease.

scientific article published in January 1986

CNS Target Identification and Validation: Avoiding the Valley of Death or Naive Optimism?

scientific article

Characterisation of learning and memory deficits following NMDA receptor antagonism

scientific article published in March 1995

Characteristics of 125I-Bolton-Hunter labelled cholecystokinin binding in human brain ⬇️

scientific article published on February 1, 1988

Characteristics of 3H-cis-flupenthixol binding to calf brain membranes

scientific article published on 01 August 1980

Chlormethiazole antagonises seizures induced by N-methyl-DL-aspartate without interacting with the NMDA receptor complex.

scientific article published in January 1993

Clomethiazole is neuroprotective in models of global and focal cerebral ischemia when infused at doses producing clinically relevant plasma concentrations

scientific article published on 01 April 2000

Clomethiazole protects against hemineglect in a primate model of stroke

scientific article published on 01 May 2000

Derisking Psychiatric Drug Development: The NIMH's Fast Fail Program, A Novel Precompetitive Model.

scientific article published on 8 July 2016

Developmental and genetic regulation of the human cortex transcriptome illuminate schizophrenia pathogenesis

scientific article published on 26 July 2018

Developmental seizures and mortality result from reducing GABA receptor α2-subunit interaction with collybistin

scientific article published in Nature Communications

Dopamine D1 receptors in human parathyroid gland: in vitro and in vivo studies

scientific article published on 01 August 1983

Early postnatal GABAA receptor modulation reverses deficits in neuronal maturation in a conditional neurodevelopmental mouse model of DISC1.

scientific article

Effect of NXY-059 on infarct volume after transient or permanent middle cerebral artery occlusion in the rat; studies on dose, plasma concentration and therapeutic time window

scientific article

Effect of chlormethiazole, dizocilpine and pentobarbital on harmaline-induced increase of cerebellar cyclic GMP and tremor.

scientific article published in January 1993

Effect of chronic amphetamine administration on central dopaminergic mechanisms in the vervet

scientific article published on 01 January 1981

Elevation of neuropeptide Y (NPY) in substantia innominata in Alzheimer's type dementia.

scientific article published in June 1984

From bench to bedside: mGluR2 positive allosteric modulators as medications to treat substance use disorders.

scientific article published on 20 December 2016

Functional benefit from clomethiazole treatment after focal cerebral ischemia in a nonhuman primate species.

scientific article published in March 1999

High affinity serotonin binding sites in human brain: a comparison of cerebral cortex and basal ganglia

scientific article published on 01 January 1989

Irreversible interaction of β-haloalkylamine derivatives with dopamine D1 and D2 receptors ⬇️

scientific article published on June 13, 1983

Kainic acid lesions dissociate [3H] spiperone and [3H]cis-flupenthixol binding sites in rat striatum

scientific article published on 01 May 1981

Loss of cortical GABA uptake sites in Alzheimer's disease

scientific article published on 01 January 1988

Metabotropic Glutamate Receptors 2 and 3 as Targets for Treating Nicotine Addiction.

scientific article

Monoamine metabolism in senile dementia of Alzheimer type.

scientific article

Muscarinic cholinergic receptors in a rat phaeochromocytoma cell line

scientific article published on 01 February 1984

Neurochemical activities in human temporal lobe related to aging and Alzheimer-type changes ⬇️

scientific article published on January 1, 1981

Neuropathological and biochemical observations on the noradrenergic system in Alzheimer's disease.

scientific article published in August 1981

Neuropeptides in Alzheimer type dementia ⬇️

scientific article published on December 1, 1983

Neuroprotective efficacy of AR-A008055, a clomethiazole analogue, in a global model of acute ischaemic stroke and its effect on ischaemia-induced glutamate and GABA efflux in vitro.

scientific article published in August 2001

Neurotransmitter metabolites, enzymes and receptors in experimental scrapie.

scientific article published in September 1985

Neurotransmitter receptors and monoamine metabolites in the brains of patients with Alzheimer-type dementia and depression, and suicides.

scientific article published in December 1984

Neurotransmitter receptors as glycoproteins ⬇️

scientific article published on October 15, 1983

Neurotransmitters and second messengers in aging and Alzheimer's disease.

scientific article published on September 1993

Novel inhibitors of As(III) S-adenosylmethionine methyltransferase (AS3MT) identified by virtual screening

scientific article published on 14 August 2018

Preferential inhibition of ligand binding to calf striatal dopamine D1 receptors by SCH 23390 ⬇️

scientific article published on November 1, 1983

Quetiapine and its metabolite norquetiapine: translation from in vitro pharmacology to in vivo efficacy in rodent models.

scientific article published on 5 October 2015

Reduced d-[3H]aspartate binding in Down's syndrome brains

scientific article published on 01 April 1989

Reversal by tetrahydroaminoacridine of scopolamine-induced memory and performance deficits in rats ⬇️

scientific article published on January 1, 1991

Review of the pharmacology and clinical pharmacology of 3,4-methylenedioxymethamphetamine (MDMA or "Ecstasy").

scientific article

Serotonin in Alzheimer-type dementia and other dementing illnesses.

scientific article published on January 1990

Serotonin receptor changes in dementia of the Alzheimer type.

scientific article published in December 1984

Sites of the neurotoxic action of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in the macaque monkey include the ventral tegmental area and the locus coeruleus.

scientific article published in October 1985

Spontaneous orofacial dyskinesia and dopaminergic function in rats after 6 months of neuroleptic treatment

scientific article

Striatal dopamine receptors in Alzheimer-type dementia.

scientific article published in November 1984

Studies on neurotransmitter receptor systems in neocortex and hippocampus in senile dementia of the Alzheimer-type.

scientific article published in May 1984

Studies on possible mechanisms of action of electroconvulsive therapy; effects of repeated electrically induced seizures on rat brain receptors for monoamines and other neurotransmitters

scientific article published on 01 January 1981

Studies on the enhancement of 5-hydroxytryptamine-mediated behaviour by chlormethiazole and phenytoin.

scientific article published in January 1992

Substantia Nigra ?-Aminobutyric Acid Receptors in Huntington's Disease ⬇️

scientific article published on August 1, 1981

The binding of [3H]thienyl cyclohexylpiperidine ([3H]TCP) to the NMDA-phencyclidine receptor complex

scientific article (publication date: 1989)

The central nervous system effects of the partial GABA-Aα2,3 -selective receptor modulator AZD7325 in comparison with lorazepam in healthy males.

scientific article published on December 2014

The concurrent estimation of the major monoamine metabolites in human and non-human primate brain by HPLC with fluorescence and electrochemical detection

scientific article published on 01 February 1981

The effects of the nonselective benzodiazepine lorazepam and the α2 /α3 subunit-selective GABAA receptor modulators AZD7325 and AZD6280 on plasma prolactin levels

scientific article published on 28 August 2014

The interaction of AR-A008055 and its enantiomers with the GABA(A) receptor complex and their sedative, muscle relaxant and anticonvulsant activity.

scientific article published in August 2001

The mGluR2 Positive Allosteric Modulator, AZD8529, and Cue-Induced Relapse to Alcohol Seeking in Rats

scientific article published on 24 June 2016

The neuroprotective actions of chlormethiazole.

scientific article published on December 1994

The neuroprotective effect of chlormethiazole on ischaemic neuronal damage following permanent middle cerebral artery ischaemia in the rat

scientific article published on 01 September 1995

The neurotoxic effects of methamphetamine on 5-hydroxytryptamine and dopamine in brain: evidence for the protective effect of chlormethiazole

scientific article (publication date: April 1992)

The striatonigral GABA pathway: functional and neurochemical characteristics in rats with unilateral striatal kainic acid lesions

scientific article published on 01 October 1980

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