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List of works by Mark Exley

Activation of CD1d-restricted T cells protects NOD mice from developing diabetes by regulating dendritic cell subsets ⬇️

scientific article published on November 13, 2001

Activation of human invariant natural killer T cells with a thioglycoside analogue of α-galactosylceramide.

scientific article published on 13 April 2011

Activation of natural killer T cells by alpha-galactosylceramide in the presence of CD1d provides protection against colitis in mice

scientific article published on 01 July 2000

Adipose tissue invariant NKT cells protect against diet-induced obesity and metabolic disorder through regulatory cytokine production.

scientific article published on 13 September 2012

Association of phosphatidylinositol 3-kinase with a specific sequence of the T cell receptor zeta chain is dependent on T cell activation

scientific article published on 01 May 1994

CD1-reactive natural killer T cells are required for development of systemic tolerance through an immune-privileged site.

scientific article

CD161 (NKR-P1A) Costimulation of CD1d-dependent Activation of Human T Cells Expressing Invariant Vα24JαQ T Cell Receptor α Chains ⬇️

scientific article published on September 7, 1998

CD1d activation and blockade: a new antitumor strategy

scientific article

CD1d and invariant NKT cells at the human maternal-fetal interface.

scientific article

CD1d favors MHC neighborhood, GM1 ganglioside proximity and low detergent sensitive membrane regions on the surface of B lymphocytes

scientific article published on 25 October 2013

CD1d mediates T-cell-dependent resistance to secondary infection with encephalomyocarditis virus (EMCV) in vitro and immune response to EMCV infection in vivo.

scientific article published on July 2006

CD1d structure and regulation on human thymocytes, peripheral blood T cells, B cells and monocytes

scientific article published on 01 May 2000

CD1d-based combination therapy eradicates established tumors in mice.

scientific article

CD1d-dependent macrophage-mediated clearance of Pseudomonas aeruginosa from lung

scientific article published on 01 June 2002

Circulating microparticles as disease-specific biomarkers of severity of inflammation in patients with hepatitis C or nonalcoholic steatohepatitis.

scientific article

Comment on “Essential Role of IL-17A in the Formation of a Mycobacterial Infection-Induced Granuloma in the Lung” ⬇️

scientific article published on August 15, 2010

Coupling of T-cell activation with T-cell receptor assembly.

scientific article

Cutting Edge: A Major Fraction of Human Bone Marrow Lymphocytes Are Th2-Like CD1d-Reactive T Cells That Can Suppress Mixed Lymphocyte Responses ⬇️

scientific article published on November 15, 2001

Cutting edge: CD1d restriction and Th1/Th2/Th17 cytokine secretion by human Vδ3 T cells.

scientific article published on 05 June 2013

Cutting edge: Compartmentalization of Th1-like noninvariant CD1d-reactive T cells in hepatitis C virus-infected liver.

scientific article published on February 2002

Defective NKT cell activation by CD1d+ TRAMP prostate tumor cells is corrected by interleukin-12 with α-galactosylceramide.

scientific article

Direct CD1d-mediated stimulation of APC IL-12 production and protective immune response to virus infection in vivo.

scientific article published on 30 November 2009

Editorial: NKT get the 'flu: NKT cells as (mostly) good guys in influenza; monocytic cells as double agents ⬇️

scientific article published on 01 March 2012

Effects of the administration of high-dose interleukin-2 on immunoregulatory cell subsets in patients with advanced melanoma and renal cell cancer

scientific article published on 01 April 2007

Efficacy of a therapeutic cocaine vaccine in rodent models.

scientific article published in October 1996

Essential role for the prolyl isomerase Pin1 in Toll-like receptor signaling and type I interferon–mediated immunity ⬇️

scientific article published on July 10, 2011

Evidence for multivalent structure of T-cell antigen receptor complex ⬇️

scientific article published on August 1, 1995

Evidence for phosphatidylinositol 3-kinase-dependent T cell antigen receptor (TCR) signal transduction ⬇️

scientific article published on February 1, 1997

Ex vivo analysis of resident hepatic pro-inflammatory CD1d-reactive T cells and hepatocyte surface CD1d expression in hepatitis C.

scientific article

Exploiting regulatory T-cell populations for the immunotherapy of cancer.

scientific article published on September 2007

Extracellular adenosine controls NKT-cell-dependent hepatitis induction

scientific article published on 19 February 2014

Extreme Th1 bias of invariant Vα24JαQ T cells in type 1 diabetes ⬇️

scientific article published on January 8, 1998

Generation of antitumor invariant natural killer T cell lines in multiple myeloma and promotion of their functions via lenalidomide: a strategy for immunotherapy.

scientific article

Gestation stage-dependent mechanisms of invariant natural killer T cell-mediated pregnancy loss

scholarly article

HDAC inhibition by LBH589 affects the phenotype and function of human myeloid dendritic cells.

scientific article published on 19 November 2010

Hepatic CD1d expression in hepatitis C virus infection and recognition by resident proinflammatory CD1d-reactive T cells.

scientific article published on August 2004

Hepatitis C Virus (HCV)-Specific CD8+ Cells Produce Transforming Growth Factor That Can Suppress HCV-Specific T-Cell Responses

scientific article (publication date: June 2007)

Human CD1d functions as a transplantation antigen and a restriction element in mice.

scientific article published on March 2001

Human invariant NKT cell subsets differentially promote differentiation, antibody production, and T cell stimulation by B cells in vitro

scientific article published on 12 July 2013

Impaired cell surface expression of human CD1d by the formation of an HIV-1 Nef/CD1d complex.

scientific article

Interplay between the immune system and adipose tissue in obesity

scientific article published on 16 September 2014

Invariant Natural Killer T Cells are Reduced in Hereditary Hemochromatosis Patients

scientific article published on 6 December 2014

Invariant natural killer T cells from rhesus macaque spleen and peripheral blood are phenotypically and functionally distinct populations.

scientific article published in February 2008

Involvement of CD1 in peripheral deletion of T lymphocytes is independent of NK T cells

scientific article published on 01 March 2001

Involvement of the iNKT cell pathway is associated with early-onset eosinophilic esophagitis and response to allergen avoidance therapy

scientific article

Islet allograft tolerance in the absence of invariant natural killer T cells

scientific article published on 23 September 2011

Isolation and functional use of human NK T cells.

scientific article published on February 2003

Isolation and functional use of human NKT cells

scientific article published on 01 August 2010

Lack of reverse transcriptase activity in serum in sporadic post-transfusional and presumed epidemic or water-borne forms of severe non-A, non-B hepatitis.

scientific article

Loss of IFN-gamma production by invariant NK T cells in advanced cancer.

scientific article published in October 2001

Microsomal triglyceride transfer protein lipidation and control of CD1d on antigen-presenting cells.

scientific article

NK T cell-derived IL-10 is essential for the differentiation of antigen-specific T regulatory cells in systemic tolerance

scientific article published on 01 January 2001

NKT-cell-based immunotherapies in clinical trials ⬇️

scientific article published on April 28, 2011

Natural killer T cell dysfunction in CD39-null mice protects against concanavalin A-induced hepatitis

scientific article

Natural killer T cell-based cancer immunotherapy

scientific article published on 01 October 2006

Nonclassical CD1d-restricted NK T cells that produce IL-13 characterize an atypical Th2 response in ulcerative colitis.

scientific article

Nuancing the proposed role of NKT cells in aging ⬇️

scientific article published on March 1, 2011

Peripheral blood progenitor cell product contains Th1-biased noninvariant CD1d-reactive natural killer T cells: implications for posttransplant survival.

scientific article published on 08 February 2008

Phenotypic and functional characterization of long-term cultured rhesus macaque spleen-derived NKT cells.

scientific article published in September 2003

Productive infection and cell-free transmission of human T-cell leukemia virus in a nonlymphoid cell line.

scientific article published in December 1983

Protective role of regulatory decidual γδ T cells in pregnancy

scientific article published on 16 September 2011

Pulmonary Natural Killer T Cells Play an Essential Role in Mediating Hyperoxic Acute Lung Injury ⬇️

scientific article published on May 1, 2013

Regulation of selective protein degradation in the endoplasmic reticulum by redox potential.

scientific article published in September 1993

Requirements for CD1d recognition by human invariant Valpha24+ CD4-CD8- T cells

scientific article

Role of CD1d in coxsackievirus B3-induced myocarditis.

scientific article published in March 2003

Selective activation, expansion, and monitoring of human iNKT cells with a monoclonal antibody specific for the TCR alpha-chain CDR3 loop.

scientific article published on June 2008

Shaping of iNKT cell repertoire after unrelated cord blood transplantation.

scientific article published on 13 February 2010

Structure, assembly and intracellular transport of the T cell receptor for antigen.

scientific article published on September 1991

The CD1d-binding glycolipid alpha-galactosylceramide enhances humoral immunity to T-dependent and T-independent antigen in a CD1d-dependent manner

scientific article published on 22 June 2006

To be or not to be NKT: natural killer T cells in the liver.

scientific article published in November 2004

Tyrosine Phosphorylation of the CD3-ε Subunit of the T Cell Antigen Receptor Mediates Enhanced Association with Phosphatidylinositol 3-Kinase in Jurkat T Cells ⬇️

scientific article published on October 3, 1997

Vgamma4(+) T cells promote autoimmune CD8(+) cytolytic T-lymphocyte activation in coxsackievirus B3-induced myocarditis in mice: role for CD4(+) Th1 cells.

scientific article published on November 2002

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