List of works - Milan Stefek

(2-Benzyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-8-yl)-acetic acid: an aldose reductase inhibitor and antioxidant of zwitterionic nature.

scientific article published on 4 October 2011

10-oxomorphine, a decomposition product of morphine

scientific article published on September 1978

2,4-dinitrophenylhydrazine carbonyl assay in metal-catalysed protein glycoxidation

scientific article published on 01 January 1999

2-Chloro-1,4-naphthoquinone derivative of quercetin as an inhibitor of aldose reductase and anti-inflammatory agent.

scientific article published on 25 March 2014

3-Mercapto-5H-1,2,4-Triazino[5,6-b]Indole-5-Acetic Acid (Cemtirestat) Alleviates Symptoms of Peripheral Diabetic Neuropathy in Zucker Diabetic Fatty (ZDF) Rats: A Role of Aldose Reductase

scientific article published on 28 January 2019

A novel carboxymethylated mercaptotriazinoindole inhibitor of aldose reductase interferes with the polyol pathway in streptozotocin-induced diabetic rats.

scientific article published in January 2015

A novel zwitterionic inhibitor of aldose reductase interferes with polyol pathway in ex vivo and in vivo models of diabetic complications

scientific article published in October 2014

Adaptive changes of antioxidant status in development of experimental diabetes

scientific article published in January 2001

Aldose reductase inhibitory activity and antioxidant capacity of pomegranate extracts.

scientific article published on March 2012

Antioxidant SMe1EC2 modulates pentose phosphate pathway and glutathione-dependent enzyme activities in tissues of aged diabetic rats

scientific article published on 01 December 2017

Antioxidant action of 3-mercapto-5H-1,2,4-triazino[5,6-b]indole-5-acetic acid, an efficient aldose reductase inhibitor, in a 1,1'-diphenyl-2-picrylhydrazyl assay and in the cellular system of isolated erythrocytes exposed to tert-butyl hydroperoxide

scientific article published on 11 June 2015

Antioxidant action of SMe1EC2, the low-basicity derivative of the pyridoindole stobadine, in cell free chemical models and at cellular level.

scientific article published on March 2014

Antioxidant action of the hexahydropyridoindole SMe1EC2 in the cellular system of isolated red blood cells in vitro.

scientific article published in January 2013

Antioxidants in treating pathologies involving oxidative damage: an update on medicinal chemistry and biological activity of stobadine and related pyridoindoles

scientific article published on January 2010

Antiradical and antioxidant activities of alkaloids isolated from Mahonia aquifolium. Structural aspects.

scientific article published in September 2004

Artichoke leaf extract, as AKR1B1 inhibitor, decreases sorbitol level in the rat eye lenses under high glucose conditions ex vivo

scientific article published on 15 August 2018

Biotransformation of stobadine, a gamma-carboline antiarrhythmic and cardioprotective agent, in rat liver microsomes

scientific article published on 01 September 1987

CHNQ, a novel 2-Chloro-1,4-naphthoquinone derivative of quercetin, induces oxidative stress and autophagy both in vitro and in vivo

scientific article published on 03 March 2016

Carboxymethylated pyridoindole antioxidants as aldose reductase inhibitors: Synthesis, activity, partitioning, and molecular modeling.

scientific article published on 17 March 2008

Carboxymethylated tetrahydropyridoindoles as aldose reductase inhibitors: in vitro selectivity study in intact rat erythrocytes in relation to glycolytic pathway.

scientific article published in December 2009

Cardiac effects of endothelin-1 (ET-1) and related C terminal peptide fragment: increased inotropy or contribution to heart failure?

scientific article published on 01 January 2003

Changes in the function and ultrastructure of vessels in the rat model of multiple low dose streptozotocin-induced diabetes

scientific article published on 01 September 2006

Cytochrome P-455 nm complex formation in the metabolism of phenylalkylamines. XIII. Enzyme interactions with a series of beta-alkyl-substituted 2-phenylethanamines and corresponding N-hydroxylamines

scientific article published on January 1992

Decision support and data analysis tools for risk assessment in primary preventive study of atherosclerosis.

scientific article

Decreasing acidity in a series of aldose reductase inhibitors: 2-Fluoro-4-(1H-pyrrol-1-yl)phenol as a scaffold for improved membrane permeation

scientific article published on 26 February 2014

Design and synthesis of N-(3,5-difluoro-4-hydroxyphenyl)benzenesulfonamides as aldose reductase inhibitors

scientific article published on 30 January 2008

Determination of ethimizol and two of its metabolites in serum by high-pressure liquid chromatography

scientific article published on 01 January 1983

Determination of pentacaine, trans-2-(1-pyrrolidinyl)cyclohexyl-3-pentyloxycarbanilate hydrochloride, in biological samples by gas chromatography/mass spectrometry.

scientific article published on August 1985

Development of Novel Oxotriazinoindole Inhibitors of Aldose Reductase: Isosteric Sulfur/Oxygen Replacement in the Thioxotriazinoindole Cemtirestat Markedly Improved Inhibition Selectivity

scientific article published on 30 December 2019

Dietary supplementation of the pyridoindole antioxidant stobadine reduces vascular impairment in streptozotocin-diabetic rats

scientific article published in April 2001

Disposition of ethimizol, a xanthine-related nootropic drug, in perfused rat liver and isolated hepatocytes

scientific article published on 01 January 1990

Does inhibition of aldose reductase contribute to the anti-inflammatory action of setipiprant?

scientific article published on 12 April 2017

Effect of Kampo medicines on alloxan-induced diabetes in mice.

scientific article published in October 1994

Effect of carboxymethylated pyridoindoles on free radical-induced haemolysis of rat erythrocytes in vitro

scientific article published on 11 January 2010

Effect of dietary supplementation with the pyridoindole antioxidant stobadine on antioxidant state and ultrastructure of diabetic rat myocardium

scientific article published on 01 January 2000

Effect of stobadine on leukocyte free radical generation in streptozotocin-diabetic rats: comparison with vitamin E.

scientific article

Effect of the pyridoindole antioxidant stobadine on ATP-utilisation by renal Na,K-ATPase in rats with streptozotocin-induced diabetes.

scientific article published in September 2007

Effect of the pyridoindole antioxidant stobadine on development of experimental diabetic cataract and on lens protein oxidation in rats: comparison with vitamin E and BHT.

scientific article

Effect of the pyridoindole antioxidant stobadine on sodium handling of renal Na,K-ATPase in rats with streptozotocin-induced diabetes.

scientific article published in December 2004

Effect of the pyridoindole antioxidant stobadine on the cardiac Na(+),K(+)-ATPase in rats with streptozotocin-induced diabetes

scientific article published on 01 June 2006

Effects of a long-term treatment with an antioxidant pyridoindole on vascular responsiveness in diabetes-induced aging rats

scientific article published on 01 July 2011

Effects of olive leaf polyphenols against H₂O₂ toxicity in insulin secreting β-cells.

scientific article published on 7 March 2011

Effects of stobadine and vitamin E in diabetes-induced retinal abnormalities: involvement of oxidative stress

scientific article published on 01 July 2007

Electrophoretic analysis of oxidatively modified eye lens proteins in vitro: implications for diabetic cataract

scientific article published on 01 August 2005

Enhancing activity and selectivity in a series of pyrrol-1-yl-1-hydroxypyrazole-based aldose reductase inhibitors: The case of trifluoroacetylation.

scientific article

Epidemiology tools program and selected medical applications.

scientific article published in June 1997

Evaluation of data in cardiology by new software tools

scientific article published on 01 January 1997

Eye lens in aging and diabetes: effect of quercetin.

scientific article published on 06 October 2011

Formation of didesmethylethimizol (4-5-dicarbamoyl-1-ethylimidazole) in man

scientific article published on 01 April 1986

Free radical scavenging and antioxidant activities of substituted hexahydropyridoindoles. Quantitative structure-activity relationships

scientific article published on 01 April 2006

Gas chromatographic determination of pentacaine in rat serum

Gas chromatographic determination of stobadine, N-desmethylstobadine and stobadine N-oxide in rat liver microsomal incubations

scientific article published on 01 March 1987

Glycoxidative and nitrosative stress in kidney of experimental diabetic rats: effects of the prydoindole antioxidant stobadine.

scientific article published in January 2010

Hepatic uptake and metabolism of pentacaine: a study with microsomes, hepatocytes and perfused livers of rats

scientific article published in October 1985

Hydrogen peroxide-dependent liver microsomal N-demethylation and N-oxygenation of stobadine, a gamma-carboline antiarrhythmic and cardioprotective agent

scientific article published in June 1989

Identification of in vitro rat metabolites of pentacaine, a carbanilate local anaesthetic, by gas chromatography/mass spectrometry.

scientific article published in April 1986

Identification of novel aldose reductase inhibitors based on carboxymethylated mercaptotriazinoindole scaffold

scientific article

In vitro inhibition of lens aldose reductase by (2-benzyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole-8-yl)-acetic acid in enzyme preparations isolated from diabetic rats

scientific article published on December 2006

In vitro studies on the activity of japanese kampo herbal medicines Oren-Gedoku-To (TJ-15) and Toki-Shakuyaku-San (TJ-23) as scavengers of free radicals.

scientific article published in January 1994

In vitro studies on the interaction of the pyridoindole antioxidant stobadine with rat liver microsomal P450.

scientific article published in September 1993

In vivo treatment with stobadine prevents lipid peroxidation, protein glycation and calcium overload but does not ameliorate Ca2+ -ATPase activity in heart and liver of streptozotocin-diabetic rats: comparison with vitamin E.

scientific article published in October 2002

Inhibition of alloxan-induced hyperglycaemia in mice by the pyridoindole stobadine

scientific article published on 01 November 1995

Inhibition of cumene hydroperoxide-induced lipid peroxidation by a novel pyridoindole antioxidant in rat liver microsomes

scientific article published on 01 June 1992

Involvement of L-arginine-nitric oxide system in the response of isolated trachea to reactive oxygen species

scientific article

Is the common 844ins68 polymorphism in the cystathionine beta-synthase gene associated with atherosclerosis?

scientific article published on 01 June 1999

L-arginine reduces structural remodeling in the diabetic rat myocardium.

scientific article

Mechanism of action of the new beta-adrenolytic drug VUL 111 upon the cardiovascular system. 1. Beta-adrenolytic activity on peroral administration and ways of metabolic degradation (author's transl)

scientific article published on July 1978

Mechanism of anti-inflammatory action of liquorice extract and glycyrrhizin.

scientific article published in December 2007

Metabolism-induced oxidative stress is a mediator of glucose toxicity in HT22 neuronal cells.

scientific article

Molecular Interactions and Implications of Aldose Reductase Inhibition by PGA1 and Clinically Used Prostaglandins.

scientific article published on 20 October 2015

Molecular strategies to prevent, inhibit, and degrade advanced glycoxidation and advanced lipoxidation end products.

scientific article published on 07 May 2013

N-oxygenation of stobadine, a gamma-carboline antiarrhythmic and cardioprotective agent: the role of flavin-containing monooxygenase

scientific article published in February 1989

Natural and synthetic antioxidants: an updated overview

scientific article published on October 2010

Natural flavonoids as potential multifunctional agents in prevention of diabetic cataract.

scientific article published on June 2011

Neuropathy in a rat model of mild diabetes induced by multiple low doses of streptozotocin: effects of the antioxidant stobadine in comparison with a high-dose alpha-lipoic acid treatment.

scientific article published in March 2010

Novel hexahydropyridoindole derivative as prospective agent against oxidative damage in pancreatic β cells

scientific article published on 01 November 2011

Novel quercetin derivatives: From redox properties to promising treatment of oxidative stress related diseases.

scientific article published on 27 January 2017

Opposing roles of the aldo-keto reductases AKR1B1 and AKR1B10 in colorectal cancer.

scientific article published on 19 September 2017

Oxidation of liposomal membrane suppressed by flavonoids: quantitative structure-activity relationship

scientific article published on 22 September 2005

Oxidative modification of rat eye lens proteins by peroxyl radicals in vitro: protection by the chain-breaking antioxidants stobadine and Trolox

scientific article published on 10 February 2005

Oxidative modification of serum albumin in an experimental glycation model of diabetes mellitus in vitro: effect of the pyridoindole antioxidant stobadine

scientific article published on 01 January 1999

Pentose phosphate pathway, glutathione-dependent enzymes and antioxidant defense during oxidative stress in diabetic rodent brain and peripheral organs: effects of stobadine and vitamin E.

scientific article published in June 2003

Pharmacological prevention of diabetic cataract

scientific article

Protection or cytotoxicity mediated by a novel quinonoid-polyphenol compound?

scientific article published on 4 November 2014

Protective effect of stobadine on NCV in streptozotocin-diabetic rats: augmentation by vitamin E.

scientific article published in June 2008

Pyridoindole antioxidant stobadine protected bovine serum albumin against the hydroxyl radical mediated cross-linking in vitro.

scientific article published in May 2003

Pyridoindole stobadine is a potent scavenger of hydroxyl radicals

scientific article published on 01 December 1991

Reactive oxygen species induced smooth muscle responses in the intestine, vessels and airways and the effect of antioxidants

scientific article published on 01 January 1999

Reactive oxygen species mediate abnormal contractile response to sympathetic nerve stimulation and noradrenaline in the vas deferens of chronically diabetic rats: effects of in vivo treatment with antioxidants.

scientific article published in February 2005

Screening for antiradical efficiency of 21 semi-synthetic derivatives of quercetin in a DPPH assay.

scientific article published on March 2013

Serum ferritin levels in subjects at high risk of atherosclerosis

scientific article published on 01 February 2000

Stobadine inhibits doxorubicin-induced apoptosis through a caspase-9 dependent pathway in P815 mastocytoma cells

scientific article published on 18 March 2007

Stobadine protects rat kidney against ischaemia/reperfusion injury

scientific journal article

Streptozotocin diabetes-induced changes in aorta, peripheral nerves and stomach of Wistar rats

scientific article published on 01 October 1999

Streptozotocin-induced experimental diabetes in male Wistar rats

scientific article published on 01 October 1999

Structural aspects of antioxidant activity of substituted pyridoindoles.

scientific article published in January 2002

Structure optimization of tetrahydropyridoindole-based aldose reductase inhibitors improved their efficacy and selectivity.

scientific article published on 16 October 2017

Structure-activity relations on [1-(3,5-difluoro-4-hydroxyphenyl)-1H-pyrrol-3-yl]phenylmethanone. The effect of methoxy substitution on aldose reductase inhibitory activity and selectivity

scientific article published on 11 January 2011

Substituted derivatives of indole acetic acid as aldose reductase inhibitors with antioxidant activity: structure-activity relationship

scientific article published on 01 December 2011

Substituted pyridoindoles as biological antioxidants: drug design, chemical synthesis, and biological activity.

scientific article published in January 2015

Temporal relationship between lens protein oxidation and cataract development in streptozotocin-induced diabetic rats.

scientific article

The alpha carbon oxidation of some phencyclidine analogues by rat tissue and its pharmacological implications

scientific article published on 01 June 1990

The effect of enzyme induction and inhibition on the disposition of the xanthine-related nootropic drug ethimizol in perfused liver and hepatocytes of rats

scientific article published on 01 January 1990

The pyridoindole antioxidant stobadine attenuates albuminuria, enzymuria, kidney lipid peroxidation and matrix collagen cross-linking in streptozotocin-induced diabetic rats.

scientific article

The pyridoindole antioxidant stobadine attenuates histochemical changes in kidney of streptozotocin-induced diabetic rats

scientific article

The pyridoindole antioxidant stobadine inhibited glycation-induced absorbance and fluorescence changes in albumin

scientific article published on 01 March 1996

The pyridoindole antioxidant stobadine prevents alloxan-induced lipid peroxidation by inhibiting its propagation

scientific article published on 01 February 1996

Triglyceride-lowering effect of the aldose reductase inhibitor cemtirestat-another factor that may contribute to attenuation of symptoms of peripheral neuropathy in STZ-diabetic rats

scientific article published on 05 December 2019

Urinary excretion of the 1,4-dihydropyridine calcium antagonist VULM 993 and its metabolites in the rat.

scientific article published in October 2001

[5-(Benzyloxy)-1H-indol-1-yl]acetic acid, an aldose reductase inhibitor and PPARγ ligand

scientific article published on 08 September 2015

[Antioxidative activity of oren-gedoku-to (TJ-15) and toki- shakuyaku-san (TJ-23) in the liver microsomes of rats]

scientific article published on 01 October 1992

[Sonographic measurement of intimal thickness of the common carotid artery in diabetics]

scientific article published on 01 August 1999

p-Dimethylaminobenzaldehyde-reactive substances in tail tendon collagen of streptozotocin-diabetic rats: temporal relation to biomechanical properties and advanced glycation endproduct (AGE)-related fluorescence

scientific article published on 01 November 2000

List of works by Milan Stefek

(2-Benzyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol-8-yl)-acetic acid: an aldose reductase inhibitor and antioxidant of zwitterionic nature.

10-oxomorphine, a decomposition product of morphine

2,4-dinitrophenylhydrazine carbonyl assay in metal-catalysed protein glycoxidation

2-Chloro-1,4-naphthoquinone derivative of quercetin as an inhibitor of aldose reductase and anti-inflammatory agent.

3-Mercapto-5H-1,2,4-Triazino[5,6-b]Indole-5-Acetic Acid (Cemtirestat) Alleviates Symptoms of Peripheral Diabetic Neuropathy in Zucker Diabetic Fatty (ZDF) Rats: A Role of Aldose Reductase

A novel carboxymethylated mercaptotriazinoindole inhibitor of aldose reductase interferes with the polyol pathway in streptozotocin-induced diabetic rats.

A novel zwitterionic inhibitor of aldose reductase interferes with polyol pathway in ex vivo and in vivo models of diabetic complications

Adaptive changes of antioxidant status in development of experimental diabetes

Aldose reductase inhibitory activity and antioxidant capacity of pomegranate extracts.

Antioxidant SMe1EC2 modulates pentose phosphate pathway and glutathione-dependent enzyme activities in tissues of aged diabetic rats

Antioxidant action of 3-mercapto-5H-1,2,4-triazino[5,6-b]indole-5-acetic acid, an efficient aldose reductase inhibitor, in a 1,1'-diphenyl-2-picrylhydrazyl assay and in the cellular system of isolated erythrocytes exposed to tert-butyl hydroperoxide

Antioxidant action of SMe1EC2, the low-basicity derivative of the pyridoindole stobadine, in cell free chemical models and at cellular level.

Antioxidant action of the hexahydropyridoindole SMe1EC2 in the cellular system of isolated red blood cells in vitro.

Antioxidants in treating pathologies involving oxidative damage: an update on medicinal chemistry and biological activity of stobadine and related pyridoindoles

Antiradical and antioxidant activities of alkaloids isolated from Mahonia aquifolium. Structural aspects.

Artichoke leaf extract, as AKR1B1 inhibitor, decreases sorbitol level in the rat eye lenses under high glucose conditions ex vivo

Biotransformation of stobadine, a gamma-carboline antiarrhythmic and cardioprotective agent, in rat liver microsomes

CHNQ, a novel 2-Chloro-1,4-naphthoquinone derivative of quercetin, induces oxidative stress and autophagy both in vitro and in vivo

Carboxymethylated pyridoindole antioxidants as aldose reductase inhibitors: Synthesis, activity, partitioning, and molecular modeling.

Carboxymethylated tetrahydropyridoindoles as aldose reductase inhibitors: in vitro selectivity study in intact rat erythrocytes in relation to glycolytic pathway.

Cardiac effects of endothelin-1 (ET-1) and related C terminal peptide fragment: increased inotropy or contribution to heart failure?

Changes in the function and ultrastructure of vessels in the rat model of multiple low dose streptozotocin-induced diabetes

Cytochrome P-455 nm complex formation in the metabolism of phenylalkylamines. XIII. Enzyme interactions with a series of beta-alkyl-substituted 2-phenylethanamines and corresponding N-hydroxylamines

Decision support and data analysis tools for risk assessment in primary preventive study of atherosclerosis.

Decreasing acidity in a series of aldose reductase inhibitors: 2-Fluoro-4-(1H-pyrrol-1-yl)phenol as a scaffold for improved membrane permeation

Design and synthesis of N-(3,5-difluoro-4-hydroxyphenyl)benzenesulfonamides as aldose reductase inhibitors

Determination of ethimizol and two of its metabolites in serum by high-pressure liquid chromatography

Determination of pentacaine, trans-2-(1-pyrrolidinyl)cyclohexyl-3-pentyloxycarbanilate hydrochloride, in biological samples by gas chromatography/mass spectrometry.

Development of Novel Oxotriazinoindole Inhibitors of Aldose Reductase: Isosteric Sulfur/Oxygen Replacement in the Thioxotriazinoindole Cemtirestat Markedly Improved Inhibition Selectivity

Dietary supplementation of the pyridoindole antioxidant stobadine reduces vascular impairment in streptozotocin-diabetic rats

Disposition of ethimizol, a xanthine-related nootropic drug, in perfused rat liver and isolated hepatocytes

Does inhibition of aldose reductase contribute to the anti-inflammatory action of setipiprant?

Effect of Kampo medicines on alloxan-induced diabetes in mice.

Effect of carboxymethylated pyridoindoles on free radical-induced haemolysis of rat erythrocytes in vitro

Effect of dietary supplementation with the pyridoindole antioxidant stobadine on antioxidant state and ultrastructure of diabetic rat myocardium

Effect of stobadine on leukocyte free radical generation in streptozotocin-diabetic rats: comparison with vitamin E.

Effect of the pyridoindole antioxidant stobadine on ATP-utilisation by renal Na,K-ATPase in rats with streptozotocin-induced diabetes.

Effect of the pyridoindole antioxidant stobadine on development of experimental diabetic cataract and on lens protein oxidation in rats: comparison with vitamin E and BHT.

Effect of the pyridoindole antioxidant stobadine on sodium handling of renal Na,K-ATPase in rats with streptozotocin-induced diabetes.

Effect of the pyridoindole antioxidant stobadine on the cardiac Na(+),K(+)-ATPase in rats with streptozotocin-induced diabetes

Effects of a long-term treatment with an antioxidant pyridoindole on vascular responsiveness in diabetes-induced aging rats

Effects of olive leaf polyphenols against H₂O₂ toxicity in insulin secreting β-cells.

Effects of stobadine and vitamin E in diabetes-induced retinal abnormalities: involvement of oxidative stress

Electrophoretic analysis of oxidatively modified eye lens proteins in vitro: implications for diabetic cataract

Enhancing activity and selectivity in a series of pyrrol-1-yl-1-hydroxypyrazole-based aldose reductase inhibitors: The case of trifluoroacetylation.

Epidemiology tools program and selected medical applications.

Evaluation of data in cardiology by new software tools

Eye lens in aging and diabetes: effect of quercetin.

Formation of didesmethylethimizol (4-5-dicarbamoyl-1-ethylimidazole) in man

Free radical scavenging and antioxidant activities of substituted hexahydropyridoindoles. Quantitative structure-activity relationships

Gas chromatographic determination of pentacaine in rat serum

Gas chromatographic determination of stobadine, N-desmethylstobadine and stobadine N-oxide in rat liver microsomal incubations

Glycoxidative and nitrosative stress in kidney of experimental diabetic rats: effects of the prydoindole antioxidant stobadine.

Hepatic uptake and metabolism of pentacaine: a study with microsomes, hepatocytes and perfused livers of rats

Hydrogen peroxide-dependent liver microsomal N-demethylation and N-oxygenation of stobadine, a gamma-carboline antiarrhythmic and cardioprotective agent

Identification of in vitro rat metabolites of pentacaine, a carbanilate local anaesthetic, by gas chromatography/mass spectrometry.

Identification of novel aldose reductase inhibitors based on carboxymethylated mercaptotriazinoindole scaffold

In vitro inhibition of lens aldose reductase by (2-benzyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole-8-yl)-acetic acid in enzyme preparations isolated from diabetic rats

In vitro studies on the activity of japanese kampo herbal medicines Oren-Gedoku-To (TJ-15) and Toki-Shakuyaku-San (TJ-23) as scavengers of free radicals.

In vitro studies on the interaction of the pyridoindole antioxidant stobadine with rat liver microsomal P450.

In vivo treatment with stobadine prevents lipid peroxidation, protein glycation and calcium overload but does not ameliorate Ca2+ -ATPase activity in heart and liver of streptozotocin-diabetic rats: comparison with vitamin E.

Inhibition of alloxan-induced hyperglycaemia in mice by the pyridoindole stobadine

Inhibition of cumene hydroperoxide-induced lipid peroxidation by a novel pyridoindole antioxidant in rat liver microsomes

Involvement of L-arginine-nitric oxide system in the response of isolated trachea to reactive oxygen species

Is the common 844ins68 polymorphism in the cystathionine beta-synthase gene associated with atherosclerosis?

L-arginine reduces structural remodeling in the diabetic rat myocardium.

Mechanism of action of the new beta-adrenolytic drug VUL 111 upon the cardiovascular system. 1. Beta-adrenolytic activity on peroral administration and ways of metabolic degradation (author's transl)

Mechanism of anti-inflammatory action of liquorice extract and glycyrrhizin.

Metabolism-induced oxidative stress is a mediator of glucose toxicity in HT22 neuronal cells.

Molecular Interactions and Implications of Aldose Reductase Inhibition by PGA1 and Clinically Used Prostaglandins.

Molecular strategies to prevent, inhibit, and degrade advanced glycoxidation and advanced lipoxidation end products.

N-oxygenation of stobadine, a gamma-carboline antiarrhythmic and cardioprotective agent: the role of flavin-containing monooxygenase

Natural and synthetic antioxidants: an updated overview

Natural flavonoids as potential multifunctional agents in prevention of diabetic cataract.

Neuropathy in a rat model of mild diabetes induced by multiple low doses of streptozotocin: effects of the antioxidant stobadine in comparison with a high-dose alpha-lipoic acid treatment.

Novel hexahydropyridoindole derivative as prospective agent against oxidative damage in pancreatic β cells

Novel quercetin derivatives: From redox properties to promising treatment of oxidative stress related diseases.

Opposing roles of the aldo-keto reductases AKR1B1 and AKR1B10 in colorectal cancer.

Oxidation of liposomal membrane suppressed by flavonoids: quantitative structure-activity relationship