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List of works by Alain Mauviel

A central role for the JNK pathway in mediating the antagonistic activity of pro-inflammatory cytokines against transforming growth factor-beta-driven SMAD3/4-specific gene expression.

scientific article published on 7 November 2002

A proximal element within the human α2(I) collagen (COL1A2) promoter, distinct from the tumor necrosis factor-α response element, mediates transcriptional repression by interferon-γ ⬇️

scientific article published on March 1, 1998

Advanced glycation end products regulate extracellular matrix protein and protease expression by human glomerular mesangial cells.

scientific article published in April 2009

Amelioration of radiation-induced fibrosis: inhibition of transforming growth factor-beta signaling by halofuginone.

scientific article published on 19 January 2004

An AP-1 binding sequence is essential for regulation of the human alpha2(I) collagen (COL1A2) promoter activity by transforming growth factor-beta.

scientific article

Analysis of gene expression dynamics revealed delayed and abnormal epidermal repair process in aged compared to young skin

scientific article

Cell density sensing alters TGF-β signaling in a cell-type-specific manner, independent from Hippo pathway activation

scientific article

Cell-specific induction of distinct oncogenes of the Jun family is responsible for differential regulation of collagenase gene expression by transforming growth factor-beta in fibroblasts and keratinocytes.

scientific article

Characterization of proteoglycans synthesized by rabbit articular chondrocytes in response to transforming growth factor-beta (TGF-beta)

scientific article published on 01 July 1991

Comparative effects of interleukin-1 and tumor necrosis factor-alpha on collagen production and corresponding procollagen mRNA levels in human dermal fibroblasts

scientific article published on 01 February 1991

Control of connective tissue gene expression by TGF beta: role of Smad proteins in fibrosis.

scientific article

Crosstalk between TGF-β and hedgehog signaling in cancer.

scientific article published on 15 May 2012

Crosstalk mechanisms between the mitogen-activated protein kinase pathways and Smad signaling downstream of TGF-beta: implications for carcinogenesis.

scientific article

Cyclic adenosine 3',5'-monophosphate-elevating agents inhibit transforming growth factor-beta-induced SMAD3/4-dependent transcription via a protein kinase A-dependent mechanism.

scientific article

Cytokine modulation of type XV collagen gene expression in human dermal fibroblast cultures

scientific article published on 01 October 1999

Differential cytokine modulation of the genes LAMA3, LAMB3, and LAMC2, encoding the constitutive polypeptides, alpha 3, beta 3, and gamma 2, of human laminin 5 in epidermal keratinocytes

scientific article published on 01 July 1995

Differential expression of extracellular matrix metalloproteinase inducer (CD147) in normal and ulcerated corneas: role in epithelio-stromal interactions and matrix metalloproteinase induction.

scientific article published on January 2005

Disruption of basal JNK activity differentially affects key fibroblast functions important for wound healing.

scientific article published on May 2003

Distinct involvement of the Jun-N-terminal kinase and NF-kappaB pathways in the repression of the human COL1A2 gene by TNF-alpha.

scientific article published on 22 October 2002

Downregulation of human type VII collagen (COL7A1) promoter activity by dexamethasone. Identification of a glucocorticoid receptor binding region.

scientific article published in February 2001

EMMPRIN/CD147, an MMP modulator in cancer, development and tissue repair.

scientific article

Efficient TGF-β/SMAD signaling in human melanoma cells associated with high c-SKI/SnoN expression.

scientific article

Expression of Microphthalmia-associated Transcription Factor (MITF), Which Is Critical for Melanoma Progression, Is Inhibited by Both Transcription Factor GLI2 and Transforming Growth Factor-β ⬇️

scientific article published on April 11, 2012

GLI2 cooperates with ZEB1 for transcriptional repression of CDH1 expression in human melanoma cells ⬇️

scientific article published on August 12, 2013

Gene expression of fibroblast matrix proteins is altered by indomethacin

scientific article published on 01 April 1988

How Bad Is the Hedgehog? GLI-Dependent, Hedgehog-Independent Cancers on the Importance of Biomarkers for Proper Patients Selection

scientific article published on 01 December 2018

Human T-cell lymphotropic virus oncoprotein Tax represses TGF-beta 1 signaling in human T cells via c-Jun activation: a potential mechanism of HTLV-I leukemogenesis.

scientific article published on 25 July 2002

Human recombinant interleukin-1 regulates cellular mRNA levels of dermatan sulphate proteoglycan core protein.

scientific article published on May 1988

Identification of a bimodal regulatory element encompassing a canonical AP-1 binding site in the proximal promoter region of the human decorin gene.

scientific article

Identification of novel TGF-beta /Smad gene targets in dermal fibroblasts using a combined cDNA microarray/promoter transactivation approach.

scientific article published on 08 March 2001

In vitro evidence for a direct antifibrotic role of the immunosuppressive drug mycophenolate mofetil

scientific article published on 01 February 2007

Increased cAMP levels modulate transforming growth factor-beta/Smad-induced expression of extracellular matrix components and other key fibroblast effector functions.

scientific article published on 26 October 2009

Induction of interleukin-1 beta production in human dermal fibroblasts by interleukin-1 alpha and tumor necrosis factor-alpha. Involvement of protein kinase-dependent and adenylate cyclase-dependent regulatory pathways

scientific article published on 01 October 1991

Induction of the AP-1 members c-Jun and JunB by TGF-beta/Smad suppresses early Smad-driven gene activation

scientific article published on 01 April 2001

Insights into the Transforming Growth Factor-β Signaling Pathway in Cutaneous Melanoma ⬇️

scientific article published on May 1, 2013

Integrating developmental signals: a Hippo in the (path)way ⬇️

scientific article published on August 29, 2011

Interferon-gamma coordinately upregulates matrix metalloprotease (MMP)-1 and MMP-3, but not tissue inhibitor of metalloproteases (TIMP), expression in cultured keratinocytes

scientific article published on 01 March 1995

Involvement of ERK signaling in halofuginone-driven inhibition of fibroblast ability to contract collagen lattices.

scientific article published on 24 July 2007

Involvement of the AP-1 site within the 5'-flanking region of the stromelysin-1 gene in induction of the gene expression by UVA irradiation

scientific article published on 01 September 1996

JNK supports survival in melanoma cells by controlling cell cycle arrest and apoptosis.

scientific article

Jun D cooperates with p65 to activate the proximal kappaB site of the cyclin D1 promoter: role of PI3K/PDK-1.

scientific article

Large scale study of epidermal recovery after stratum corneum removal: dynamics of genomic response

scientific article published on 17 September 2009

Leukoregulin down-regulates type I collagen mRNA levels and promoter activity in human dermal fibroblasts, and counteracts the up-regulation elicited by transforming growth factor-β ⬇️

scientific article published on June 15, 1992

Leukoregulin, a T-cell derived cytokine, upregulates stromelysin-1 gene expression in human dermal fibroblasts: evidence for the role of AP-1 in transcriptional activation

scientific article published on 01 September 1992

Mammalian transforming growth factor-betas: Smad signaling and physio-pathological roles.

scientific article published on July 2004

Mitogen- and stress-activated protein kinase 1 is critical for interleukin-1-induced, CREB-mediated, c-fos gene expression in keratinocytes.

scientific article published on 13 March 2006

Modulation of collagen and MMP-1 gene expression in fibroblasts by the immunosuppressive drug rapamycin. A direct role as an antifibrotic agent?

scientific article published on 16 August 2006

Modulation of extracellular matrix metabolism in rabbit articular chondrocytes and human rheumatoid synovial cells by the non-steroidal anti-inflammatory drug etodolac. I: Collagen synthesis

scientific article published on 01 November 1990

Modulation of extracellular matrix metabolism in rabbit articular chondrocytes and human rheumatoid synovial cells by the non-steroidal anti-inflammatory drug etodolac. II: Glycosaminoglycan synthesis

scientific article published on 01 November 1990

Modulation of human dermal fibroblast extracellular matrix metabolism by the lymphokine leukoregulin ⬇️

scientific article published on June 1, 1991

Molecular mechanisms underlying TGF-ß/Hippo signaling crosstalks - Role of baso-apical epithelial cell polarity

scientific article published on 12 March 2018

Overlapping activities of TGF-β and Hedgehog signaling in cancer: therapeutic targets for cancer treatment.

scientific article

Physical and functional cooperation between AP-1 and beta-catenin for the regulation of TCF-dependent genes.

scientific article published on 4 December 2006

Pro-Invasive Activity of the Hippo Pathway Effectors YAP and TAZ in Cutaneous Melanoma ⬇️

scientific article published on July 29, 2013

Propiomelanocortin (POMC) gene expression by normal skin and keloid fibroblasts in culture: modulation by cytokines

scientific article published on 01 June 1997

Retinoic acid receptors interfere with the TGF-beta/Smad signaling pathway in a ligand-specific manner.

scientific article published in November 2003

SMAD3/4-dependent transcriptional activation of the human type VII collagen gene (COL7A1) promoter by transforming growth factor beta.

scientific article published on December 1998

Skin involvement in scleroderma--where histological and clinical scores meet

scientific article published on 25 January 2007

Smad-dependent Transcriptional Activation of Human Type VII Collagen Gene (COL7A1) Promoter by Transforming Growth Factor-β ⬇️

scientific article published on May 22, 1998

Smad7 restricts melanoma invasion by restoring N-cadherin expression and establishing heterotypic cell-cell interactions in vivo.

scientific article

Stable Overexpression of Smad7 in Human Melanoma Cells Impairs Bone Metastasis

scientific article published on 01 March 2007

Structural and functional characterization of the human perlecan gene promoter. Transcriptional activation by transforming growth factor-beta via a nuclear factor 1-binding element

scientific article

Systematic classification of melanoma cells by phenotype-specific gene expression mapping.

scientific article published on 2 March 2012

TGF-β/SMAD/GLI2 signaling axis in cancer progression and metastasis

scientific article

TNF-alpha represses connexin43 expression in HaCat keratinocytes via activation of JNK signaling.

scientific article

The steroid receptor co-activator-1 (SRC-1) potentiates TGF-beta/Smad signaling: role of p300/CBP.

scientific article published on March 2005

Transcriptional regulation of decorin gene expression. Induction by quiescence and repression by tumor necrosis factor-alpha

scientific article published on 01 May 1995

Transcriptional repression of the tyrosinase-related protein 2 gene by transforming growth factor-β and the Kruppel-like transcription factor GLI2

scientific article published on 06 April 2019

Transforming growth factor beta exerts opposite effects from interleukin-1 beta on cultured rabbit articular chondrocytes through reduction of interleukin-1 receptor expression

scientific article published on 01 January 1993

Transforming growth factor beta stimulates collagen and glycosaminoglycan biosynthesis in cultured rabbit articular chondrocytes

scientific article published on 01 July 1988

Transforming growth factor-beta signaling in skin: stromal to epithelial cross-talk

scientific article published on 01 January 2009

Transforming growth factor-beta suppresses the ability of Ski to inhibit tumor metastasis by inducing its degradation.

scientific article published in May 2008

Transforming growth factor-betas: smad signaling and roles in physiopathology

scientific article

Tumor necrosis factor alpha inhibits wound healing in the rat

scientific article published on 01 January 1991

Tumor necrosis factor inhibits collagen and fibronectin synthesis in human dermal fibroblasts

scientific article published on 01 August 1988

Tumor necrosis factor-alpha inhibits transforming growth factor-beta /Smad signaling in human dermal fibroblasts via AP-1 activation

scientific article (publication date: 29 September 2000)

Uncoordinate regulation of collagenase, stromelysin, and tissue inhibitor of metalloproteinases genes by prostaglandin E2: selective enhancement of collagenase gene expression in human dermal fibroblasts in culture

scientific article published on 01 April 1994

Yes-associated protein (YAP65) interacts with Smad7 and potentiates its inhibitory activity against TGF-beta/Smad signaling

scientific article (publication date: 25 July 2002)

[Involvement of TGFbeta1 in fibrotic diseases: role of its effectors, the Smad proteins]

scientific article published on 22 November 2005

[Metalloproteinases and angiogenesis]

scientific article published on 01 April 2003

c-Fos accelerates hepatocyte conversion to a fibroblastoid phenotype through ERK-mediated upregulation of paxillin-Serine178 phosphorylation.

scientific article

c-Fos overexpression increases the proliferation of human hepatocytes by stabilizing nuclear Cyclin D1

scientific article

c-Jun associates with the oncoprotein Ski and suppresses Smad2 transcriptional activity

scientific article (publication date: 9 August 2002)

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