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List of works by Marc Feldmann

A novel mechanism for TNF-alpha regulation by p38 MAPK: involvement of NF-kappa B with implications for therapy in rheumatoid arthritis

scientific article

A novel synthetic, nonpsychoactive cannabinoid acid (HU-320) with antiinflammatory properties in murine collagen-induced arthritis

scientific article

A vasculature niche orchestrates stromal cell phenotype through PDGF signaling: Importance in human fibrotic disease

scientific article published in 2022

Advanced glycation end products upregulate angiogenic and pro-inflammatory cytokine production in human monocyte/macrophages

scientific article published on October 2004

Alarmins: awaiting a clinical response

scientific article

An inflammatory cytokine signature helps predict COVID-19 severity and death

scientific article published on 30 May 2020

Anti-TNF therapy: where have we got to in 2005?

scientific article

Anti-TNFalpha therapy of rheumatoid arthritis: what can we learn about chronic disease?

scientific article published on January 2004

Apremilast, a novel PDE4 inhibitor, inhibits spontaneous production of tumour necrosis factor-alpha from human rheumatoid synovial cells and ameliorates experimental arthritis

scientific article published on 2 June 2010

Cancer immunotherapy in routine cost-effective cancer care?

scientific article published on 01 November 2018

Canonical pathway of nuclear factor kappa B activation selectively regulates proinflammatory and prothrombotic responses in human atherosclerosis

scientific article

Could toll-like receptors provide a missing link in chronic inflammation in rheumatoid arthritis? Lessons from a study on human rheumatoid tissue

scientific article published on November 2007

Cytokine inhibitors in rheumatoid arthritis and other autoimmune diseases

scientific article

Cytokine-stimulated T cells induce macrophage IL-10 production dependent on phosphatidylinositol 3-kinase and p70S6K: implications for rheumatoid arthritis

scientific article

Cytokines and anti-cytokine biologicals in autoimmunity: present and future

scientific article

Design and optimisation of bioactive cyclic peptides: generation of a down-regulator of TNF secretion.

scientific article published on 22 December 2014

Differential effects of Th1 versus Th2 cytokines in combination with hypoxia on HIFs and angiogenesis in RA.

scientific article published on 6 August 2012

Discovery of TNF-alpha as a therapeutic target in rheumatoid arthritis: preclinical and clinical studies

scientific article

Distinct pathways of LPS-induced NF-kappa B activation and cytokine production in human myeloid and nonmyeloid cells defined by selective utilization of MyD88 and Mal/TIRAP

scientific journal article

Emerging approaches for the therapy of autoimmune and chronic inflammatory disease

scientific article

Evidence that rheumatoid arthritis synovial T cells are similar to cytokine-activated T cells: involvement of phosphatidylinositol 3-kinase and nuclear factor kappaB pathways in tumor necrosis factor alpha production in rheumatoid arthritis

scientific article published in January 2002

Gene expression profiling and functional analysis of angiogenic markers in murine collagen-induced arthritis

scientific article published on 20 July 2012

Heterogeneous requirement of IkappaB kinase 2 for inflammatory cytokine and matrix metalloproteinase production in rheumatoid arthritis: implications for therapy

scholarly article by Evangelos Andreakos et al published July 2003 in Arthritis and Rheumatism

High-efficiency gene transfer into nontransformed cells: utility for studying gene regulation and analysis of potential therapeutic targets.

scientific article

Histone H3K27me3 demethylases regulate human Th17 cell development and effector functions by impacting on metabolism

scientific article published on 02 March 2020

Historical review: Cytokines as therapeutics and targets of therapeutics

scientific article published on April 2004

How does infliximab work in rheumatoid arthritis?

scientific article

Human epidermal growth factor receptor bispecific ligand trap RB200: abrogation of collagen-induced arthritis in combination with tumour necrosis factor blockade

scientific article

IRF5 controls both acute and chronic inflammation.

scientific article

IRF5 promotes inflammatory macrophage polarization and TH1-TH17 responses

scientific article

Identification and characterization of 4-[[4-(2-butynyloxy)phenyl]sulfonyl]-N-hydroxy-2,2-dimethyl-(3S)thiomorpholinecarboxamide (TMI-1), a novel dual tumor necrosis factor-alpha-converting enzyme/matrix metalloprotease inhibitor for the treatment o

scientific article

Identifying collagen VI as a target of fibrotic diseases regulated by CREBBP/EP300

scientific article published on 05 August 2020

Ikappa B kinase 2 but not NF-kappa B-inducing kinase is essential for effective DC antigen presentation in the allogeneic mixed lymphocyte reaction

scholarly article by E. Andreakos et al published 19 September 2002 in Blood

Immunomodulatory properties of mesenchymal stem cells: a review based on an interdisciplinary meeting held at the Kennedy Institute of Rheumatology Division, London, UK, 31 October 2005

scientific article published on January 2007

Impact of VIP and cAMP on the regulation of TNF-alpha and IL-10 production: implications for rheumatoid arthritis

scientific article

In memoriam: Professor Brian Maurice John Foxwell, 1956 to 2008.

scientific article published on 27 February 2009

Inhibitors of TLR8 reduce TNF production from human rheumatoid synovial membrane cultures

scientific article published on December 2008

Investigating the role of the interleukin-23/-17A axis in rheumatoid arthritis

scientific article published on 08 October 2009

Is targeting Toll-like receptors and their signaling pathway a useful therapeutic approach to modulating cytokine-driven inflammation?

scientific article

Lasker Clinical Medical Research Award. TNF defined as a therapeutic target for rheumatoid arthritis and other autoimmune diseases

scientific article (publication date: October 2003)

Low-dose TNF augments fracture healing in normal and osteoporotic bone by up-regulating the innate immune response.

scientific article published on 14 March 2015

Molecular profile of peripheral blood mononuclear cells from patients with rheumatoid arthritis

scientific article

Molecular therapeutic targets in rheumatoid arthritis

scientific article

Monoclonal antibodies in immune and inflammatory diseases

scientific article

Nonsteroidal anti-inflammatory drugs increase TNF production in rheumatoid synovial membrane cultures and whole blood

scientific article published on 16 August 2010

Novel splice variants derived from the receptor tyrosine kinase superfamily are potential therapeutics for rheumatoid arthritis

scientific article published on July 2008

Rac mediates TNF-induced cytokine production via modulation of NF-kappaB.

scientific article published on 06 February 2008

Regulation of the angiopoietin-Tie ligand-receptor system with a novel splice variant of Tie1 reduces the severity of murine arthritis

scientific article

Reply

scientific article (publication date: December 2004)

Resistance to regulatory T cell-mediated suppression in rheumatoid arthritis can be bypassed by ectopic foxp3 expression in pathogenic synovial T cells ⬇️

scientific article published on September 16, 2011

Resting CD4+ effector memory T cells are precursors of bystander-activated effectors: a surrogate model of rheumatoid arthritis synovial T-cell function.

scientific article published on 19 March 2008

Role of interleukin-1beta in postoperative cognitive dysfunction.

scientific article

Selective Blockade of Tumor Necrosis Factor Receptor I Inhibits Proinflammatory Cytokine and Chemokine Production in Human Rheumatoid Arthritis Synovial Membrane Cell Cultures ⬇️

scientific article published on September 1, 2013

Selective use of TRAM in lipopolysaccharide (LPS) and lipoteichoic acid (LTA) induced NF-kappaB activation and cytokine production in primary human cells: TRAM is an adaptor for LPS and LTA signaling

scientific article published in February 2007

Single cell force profiling of human myofibroblasts reveals a biophysical spectrum of cell states

scientific article published on 24 March 2020

T cell-mediated signaling to vascular endothelium: induction of cytokines, chemokines, and tissue factor

T-cell-mediated signalling in immune, inflammatory and angiogenic processes: the cascade of events leading to inflammatory diseases

scientific article published on March 2004

TNF-alpha promotes fracture repair by augmenting the recruitment and differentiation of muscle-derived stromal cells

scientific article

The Role of TNFα in the Pathogenesis of Rheumatoid Synovitis.

scientific article published on 15 November 1999

The Toll-like receptor adaptor proteins MyD88 and Mal/TIRAP contribute to the inflammatory and destructive processes in a human model of rheumatoid arthritis

scientific article published on February 2007

The angiogenesis inhibitor protease-activated kringles 1–5 reduces the severity of murine collagen-induced arthritis ⬇️

scientific article published on October 31, 2002

The toll-like receptor-nuclear factor kappaB pathway in rheumatoid arthritis

scientific article

The transfer of a laboratory based hypothesis to a clinically useful therapy: the development of anti-TNF therapy of rheumatoid arthritis

scientific article published on February 2004

Towards an understanding of the role of DNA methylation in rheumatoid arthritis: therapeutic and diagnostic implications

scientific article

Tumor necrosis factor-alpha triggers a cytokine cascade yielding postoperative cognitive decline

scientific article

Tumour necrosis factor alpha as a therapeutic target for immune-mediated inflammatory diseases

scientific article

Unexpected protective role for Toll-like receptor 3 in the arterial wall

scientific article

Vascular endothelial growth factor signalling in endothelial cell survival: a role for NFkappaB.

scientific article published on 27 December 2005

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