Search filters

List of works by Afshin Zarghi

A Newly Synthetized Ferrocenyl Derivative Selectively Induces Apoptosis in ALL Lymphocytes through Mitochondrial Estrogen Receptors.

scientific article

A randomized, double-blind, placebo-controlled investigation of BCc1 nanomedicine effect on survival and quality of life in metastatic and non-metastatic gastric cancer patients

scientific article published on 10 April 2019

An investigation into the ability of alendronate ion pairs to increase oral absorption.

scientific article published on 25 May 2017

Application of monolithic column in quantification of gliclazide in human plasma by liquid chromatography

scientific article published on 23 June 2006

Design and synthesis of 1,3-diarylurea derivatives as selective cyclooxygenase (COX-2) inhibitors.

scientific article published on 11 January 2008

Design and synthesis of 3-alkyl-2-aryl-1,3-thiazinan-4-one derivatives as selective cyclooxygenase (COX-2) inhibitors.

scientific article published on 3 May 2009

Design and synthesis of new 1,3-benzdiazinan-4-one derivatives as selective cyclooxygenase (COX-2) inhibitors

scientific article published on 11 November 2011

Design and synthesis of new 2-substituted-5-(2-benzylthiophenyl)-1,3,4-oxadiazoles as benzodiazepine receptor agonists.

scientific article published in June 2005

Design and synthesis of new 2-substituted-5-[2-(2-halobenzyloxy)phenyl]-1,3,4-oxadiazoles as anticonvulsant agents.

scientific article published in April 2008

Design, Synthesis and Biological Evaluation of New 1,3-diphenyl-3- (phenylamino)propan-1-ones as Selective Cyclooxygenase (COX-2) Inhibitors

scientific article published on 01 January 2018

Design, Synthesis, and Biological Evaluation of New 2-Phenyl-4H-chromen-4-one Derivatives as Selective Cyclooxygenase-2 Inhibitors.

scientific article published on 15 September 2014

Design, Synthesis, and Biological Evaluation of New Peptide Analogues as Selective COX-2 Inhibitors.

scientific article published on 5 September 2017

Design, synthesis and biological evaluation of 7-(aryl)-2,3-dihydro-[1,4]dioxino[2,3-g]quinoline derivatives as potential Hsp90 inhibitors and anticancer agents

scientific article published on 2 January 2017

Design, synthesis and biological evaluation of new (E)- and (Z)-1,2,3-triaryl-2-propen-1-ones as selective COX-2 inhibitors

scientific article published on June 2, 2010

Design, synthesis and biological evaluation of new 2,3-diarylquinoline derivatives as selective cyclooxygenase-2 inhibitors.

scientific article published on 4 January 2010

Design, synthesis and biological evaluation of new 5,5-diarylhydantoin derivatives as selective cyclooxygenase-2 inhibitors

scientific article

Design, synthesis and biological evaluation of peptide-NSAID conjugates for targeted cancer therapy

scientific article published on 18 July 2019

Design, synthesis, and biological evaluation of 1,3-diarylprop-2-en-1-ones : a novel class of cyclooxygenase-2 inhibitors.

scientific article published on 13 December 2005

Design, synthesis, and biological evaluation of new 1,4-diarylazetidin-2-one derivatives (β-lactams) as selective cyclooxygenase-2 inhibitors

scientific article published on 09 January 2020

Design, synthesis, and biological evaluation of new pyrazino[1,2-a]benzimidazole derivatives as selective cyclooxygenase (COX-2) inhibitors

scientific article published on 18 December 2018

Development an ion-pair liquid chromatographic method for determination of sotalol in plasma using a monolithic column

scientific article published on 08 May 2006

Docking-based 3D-QSAR (CoMFA, CoMFA-RG, CoMSIA) study on hydroquinoline and thiazinan-4-one derivatives as selective COX-2 inhibitors

scientific article published on 17 November 2018

Enhancement and in vitro evaluation of amifostine permeation through artificial membrane (PAMPA) via ion pairing approach and mechanistic selection of its optimal counter ion.

scientific article published on 24 October 2013

Estrogen Receptor Ligands: A Review (2013-2015).

scientific article published on 13 April 2016

Evaluation of Cytotoxicity Effects of Chalcone Epoxide Analogues as a Selective COX-II Inhibitor in the Human Liver Carcinoma Cell Line

scientific article published on 30 September 2017

Fumonisin B(1) in maize harvested in Iran during 1999.

scientific article published in July 2002

Ion-pair strategy for enabling amifostine oral absorption: rat in situ and in vivo experiments.

scientific article published on 2 May 2013

Morphine stimulates locomotor activity by an indirect dopaminergic mechanism: possible D-1 and D-2 receptor involvement

scientific article published on 01 November 1992

Nicotine-induced hypothermia through an indirect dopaminergic mechanism

scientific article published on 01 January 1995

Novel benzoxazin-3-one derivatives: Design, synthesis, molecular modeling, anti-HIV-1 and integrase inhibitory assay

scientific article published on 26 August 2019

PAMAM-dendrimer Enhanced Antibacterial Effect of Vancomycin Hydrochloride Against Gram-Negative Bacteria

scientific article published on 01 January 2018

Rapid determination of acetazolamide in human plasma.

scientific article published in April 2002

Rapid determination of minoxidil in human plasma using ion-pair HPLC.

scientific article published in October 2004

Role of glutathione conjugation in protection of weanling rat liver against acetaminophen-induced hepatotoxicity

scientific article published on 01 April 1997

Selective COX-2 inhibitors as anticancer agents: a patent review (2014-2018)

scientific article published on 27 May 2019

Sensitive and Rapid HPLC Method for Determination of Memantine in Human Plasma Using OPA Derivatization and Fluorescence Detection: Application to Pharmacokinetic Studies

scientific article published on October 5, 2010

Sensitive high-performance liquid chromatographic method for determination of captopril in plasma

scientific article published on 01 June 1999

Simple and rapid high-performance liquid chromatographic method for determination of celecoxib in plasma using UV detection: application in pharmacokinetic studies

scientific article published on 31 March 2006

Simple high-performance liquid chromatographic determination of buspirone in human plasma.

scientific article published in September 2004

Simultaneous determination of amoxicillin and clavulanic acid in human plasma by isocratic reversed-phase HPLC using UV detection

scientific article published on 29 June 2007

Sulfonamido, azidosulfonyl and N-acetylsulfonamido analogues of rofecoxib: 4-[4-(N-acetylsulfonamido)phenyl]-3-(4-methanesulfonylphenyl)-2(5H)furanone is a potent and selective cyclooxygenase-2 inhibitor.

scientific article published in April 2004

Synthesis and anticonvulsant activity of new 2-substituted-5-(2-benzyloxyphenyl)-1,3,4-oxadiazoles.

scientific article

Synthesis and biological evaluation of 1,3-diphenylprop-2-en-1-ones possessing a methanesulfonamido or an azido pharmacophore as cyclooxygenase-1/-2 inhibitors

scientific article published on 22 June 2006

Synthesis and biological evaluation of methanesulfonamide analogues of rofecoxib: Replacement of methanesulfonyl by methanesulfonamido decreases cyclooxygenase-2 selectivity

scientific article published on 25 October 2006

Synthesis and biological evaluation of quinoline analogues of flavones as potential anticancer agents and tubulin polymerization inhibitors.

scientific article published on 2 March 2016

Synthesis and characterization of methotrexate polyethylene glycol esters as a drug delivery system.

scientific article

Synthesis and cytotoxic evaluation of two novel anthraquinone derivatives.

scientific article published on August 2004

Synthesis of 2,3-diaryl-1,3-thiazolidine-4-one derivatives as selective cyclooxygenase (COX-2) inhibitors

scientific article published on 22 August 2007

Synthesis, docking simulation, biological evaluations and 3D-QSAR study of 5-Aryl-6-(4-methylsulfonyl)-3-(metylthio)-1,2,4-triazine as selective cyclooxygenase-2 inhibitors.

scientific article

Targeting the mitochondrial apoptosis pathway by a newly synthesized COX-2 inhibitor in pediatric ALL lymphocytes

scientific article published on 11 October 2018

Validated HPLC method for determination of amlodipine in human plasma and its application to pharmacokinetic studies.

scientific article published in September 2005

β-lactam Structured, 4-(4-(Methylsulfonyl)phenyl)-1-pentyl-3-phenoxyazetidin-2-one: Selectively Targets Cancerous B Lymphocyte Mitochondria.

scientific article published on 13 February 2017