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List of works by Neil Wedlock

A DNA prime-Mycobacterium bovis BCG boost vaccination strategy for cattle induces protection against bovine tuberculosis

scientific article published on September 2003

Ability of T cell subsets and their soluble mediators to modulate the replication of Mycobacterium bovis in bovine macrophages

scientific article published in November 2004

Adrenal autoantibodies and naturally occurring mutations in 21-hydroxylase

scientific article published on 01 January 1994

Altered patterns of toll-like receptor gene expression in cull cows infected with Mycobacterium avium subsp. paratuberculosis.

scientific article

Antigen-induced interferon-gamma and interleukin-2 responses of cattle inoculated with Mycobacterium bovis

scientific article published on 01 June 1997

Autoimmune Addison's disease and 21-hydroxylase

scientific article published on 01 August 1992

Autoimmune Addison's disease--evidence for a role of steroid 21-hydroxylase autoantibodies in adrenal insufficiency

scientific article published on 01 November 1994

Autoimmune Addison's disease. Analysis of autoantibody binding sites on human steroid 21-hydroxylase.

scientific article published on October 1993

Bacterial metabolism, cytokine mRNA transcription and viability of bovine alveolar macrophages infected with Mycobacterium bovis BCG or virulent M. bovis

scientific article published on 01 February 1996

Bacterial polyester inclusions engineered to display vaccine candidate antigens for use as a novel class of safe and efficient vaccine delivery agents.

scientific article published on 16 October 2009

Bactericidal activity of macrophages against Streptococcus uberis is different in mammary gland secretions of lactating and drying off cows

scientific article published on 01 September 2006

Binding characteristics of antibodies to the TSH receptor

scientific article published on 01 April 1998

Bioengineering a bacterial pathogen to assemble its own particulate vaccine capable of inducing cellular immunity

scientific article published on 02 February 2017

Cattle as a model for development of vaccines against human tuberculosis

scientific article

Comparison of gene expression of immune mediators in lung and pulmonary lymph node granulomas from cattle experimentally infected with Mycobacterium bovis

scientific article published on 4 April 2014

Control of Mycobacterium bovis infections and the risk to human populations

scientific article

Corrigendum to "Immunogencity of antigens from Mycobacterium tuberculosis self-assembled as particulate vaccines" [Int. J. Med. Microbiol. 306 (2016) 624-632]

scientific article published on 01 February 2017

DNA Homologies between Rhizobium fredii, Rhizobia That Nodulate Galega sp., and Other Rhizobium and Bradyrhizobium Species

scientific article

DNA homology within the Rhizobiaceae

1984 master's thesis by David Neil Wedlock at Massey University

Dairy cows produce cytokine and cytotoxic T cell responses following vaccination with an antigenic fraction from Streptococcus uberis.

scientific article

Detection of microRNA in cattle serum and their potential use to diagnose severity of Johne's disease

scientific article published on 07 September 2018

Development of a vaccine to mitigate greenhouse gas emissions in agriculture: vaccination of sheep with methanogen fractions induces antibodies that block methane production in vitro.

scientific article

Development of vaccines to control bovine tuberculosis in cattle and relationship to vaccine development for other intracellular pathogens

scientific article

Differences of gene expression in bovine alveolar macrophages infected with virulent and attenuated isogenic strains of Mycobacterium bovis

scientific article published on 31 January 2006

Display of Antigens on Polyester Inclusions Lowers the Antigen Concentration Required for a Bovine Tuberculosis Skin Test

scientific article published on 28 October 2015

Diverse cytokine profile from mesenteric lymph node cells of cull cows severely affected with Johne's disease.

scientific article

Draft Genome Sequence of a New Zealand Isolate of Mycoplasma ovipneumoniae

scientific article published on 05 March 2020

Effect of different adjuvants on the immune responses of cattle vaccinated with Mycobacterium tuberculosis culture filtrate proteins.

scientific article

Effect of oral vaccination of cattle with lipid-formulated BCG on immune responses and protection against bovine tuberculosis

scientific article published on 01 May 2005

Effect of recombinant cytokines on leucocytes and physiological changes in bovine mammary glands during early involution

scientific article

Effects of yeast expressed recombinant interleukin-2 and interferon-gamma on physiological changes in bovine mammary glands and on bactericidal activity of neutrophils

scientific article published on 01 May 2000

Enhanced protection against bovine tuberculosis after coadministration of Mycobacterium bovis BCG with a Mycobacterial protein vaccine-adjuvant combination but not after coadministration of adjuvant alone

scientific article published on 12 March 2008

Enhancement of the sensitivity of the whole-blood gamma interferon assay for diagnosis of Mycobacterium bovis infections in cattle.

scientific article

Expression of human thyroid peroxidase in the yeasts Saccharomyces cerevisiae and Hansenula polymorpha

scientific article published on 01 June 1993

Genome sequencing of rumen bacteria and archaea and its application to methane mitigation strategies

scientific article published on June 2013

Grazing dairy cows had decreased interferon-γ, tumor necrosis factor, and interleukin-17, and increased expression of interleukin-10 during the first week after calving

scientific article published on 5 December 2014

Heterologous peptide display on chromatin nanofibers: A new strategy for peptide vaccines

scientific article published on 07 February 2020

IFN-gamma enhances bovine macrophage responsiveness to Mycobacterium bovis: Impact on bacterial replication, cytokine release and macrophage apoptosis

scientific article published on 01 December 2005

Identification of immune response correlates for protection against bovine tuberculosis

scientific article

Immune responses associated with progression and control of infection in calves experimentally challenged with Mycobacterium avium subsp. paratuberculosis

scientific article

Immune responses induced in cattle by virulent and attenuated Mycobacterium bovis strains: correlation of delayed-type hypersensitivity with ability of strains to grow in macrophages

scientific article

Immunogencity of antigens from Mycobacterium tuberculosis self-assembled as particulate vaccines.

scientific article published on 13 October 2016

Immunological properties and protective efficacy of a single mycobacterial antigen displayed on polyhydroxybutyrate beads.

scientific article published on 17 July 2017

In vitro control of Mycobacterium bovis by macrophages

scientific article published on 01 January 2001

Interleukin-1beta infusion in bovine mammary glands prior to challenge with Streptococcus uberis reduces bacterial growth but causes sterile mastitis

scientific article published on 19 April 2008

Investigations on the hexose-phosphorylating enzymes in the pentose-fermenting yeast, Pachysolen tannophilus

1988 doctoral thesis by David Neil Wedlock at Massey University

Low oral BCG doses fail to protect cattle against an experimental challenge with Mycobacterium bovis

scientific article published on 31 July 2011

Marsupial cytokines. Structure, function and evolution

scientific article

Molecular cloning and characterization of tumor necrosis factor alpha (TNF-alpha) from the Australian common brushtail possum, Trichosurus vulpecula

scientific article

Molecular cloning and physiological effects of brushtail possum interleukin-1beta.

scientific article published on March 1999

Mucosal immunity in the brushtail possum (Trichosurus vulpecula): detection of antibody in serum and at female reproductive sites after intranasal immunization

scientific article published on 01 August 2002

Naturally occurring mutations in human steroid 21-hydroxylase influence adrenal autoantibody binding

scientific article published on 01 August 1994

New generation vaccines and delivery systems for control of bovine tuberculosis in cattle and wildlife

scientific article published on 01 September 2002

New skin test for detection of bovine tuberculosis on the basis of antigen-displaying polyester inclusions produced by recombinant Escherichia coli.

scientific article

Novel particulate vaccines utilizing polyester nanoparticles (bio-beads) for protection against Mycobacterium bovis infection - a review

scientific article published on 30 April 2013

Nucleotide sequence of a marsupial interleukin-10 cDNA from the Australian brushtail possum (Trichosurus vulpecula).

scientific article published on January 1998

Oral vaccination of brushtail possums (Tichosurus vulpecula) with BCG: immune responses, persistence of BCG in lymphoid organs and excretion in faeces

scientific article published on 01 October 2005

Overview of vaccination trials for control of tuberculosis in cattle, wildlife and humans

scientific article

Physiological effects and adjuvanticity of recombinant brushtail possum TNF-alpha

scientific article published on 01 February 1999

Progress in the development of tuberculosis vaccines for cattle and wildlife.

scientific article

Progress in the development of vaccines against rumen methanogens.

scientific article published on June 2013

Protection against bovine tuberculosis induced by oral vaccination of cattle with Mycobacterium bovis BCG is not enhanced by co-administration of mycobacterial protein vaccines

scientific article published on 29 September 2011

Revaccination of cattle with bacille Calmette-Guérin two years after first vaccination when immunity has waned, boosted protection against challenge with Mycobacterium bovis.

scientific article

Revaccination of neonatal calves with Mycobacterium bovis BCG reduces the level of protection against bovine tuberculosis induced by a single vaccination.

scientific article

Sequential activation of alveolar macrophages by IFN-gamma and LPS is required for enhanced growth inhibition of virulent Mycobacterium bovis but not M. bovis BCG

scientific article published on 01 April 1997

Steroid 21-hydroxylase is a major autoantigen involved in adult onset autoimmune Addison's disease

scientific article published on 01 August 1992

Strategies to reduce methane emissions from farmed ruminants grazing on pasture

scientific article published on 26 March 2010

Streptococcus uberis-specific T cells are present in mammary gland secretions of cows and can be activated to kill S. uberis.

scientific article published in February 2011

Subcutaneous administration of a 10-fold-lower dose of a commercial human tuberculosis vaccine, Mycobacterium bovis bacillus Calmette-Guerin Danish, induced levels of protection against bovine tuberculosis and responses in the tuberculin intradermal

scientific article published on 07 August 2013

Susceptibility of brushtail possums (Trichosurus vulpecula) infected with Mycobacterium bovis is associated with a transient macrophage activation profile.

scientific article

The order of prime-boost vaccination of neonatal calves with Mycobacterium bovis BCG and a DNA vaccine encoding mycobacterial proteins Hsp65, Hsp70, and Apa is not critical for enhancing protection against bovine tuberculosis.

scientific article

Update on vaccination of cattle and wildlife populations against tuberculosis.

scientific article published on 24 February 2011

Vaccination of Sheep with a Methanogen Protein Provides Insight into Levels of Antibody in Saliva Needed to Target Ruminal Methanogens

scientific article

Vaccination of animals against Mycobacterium bovis

scientific article

Vaccination of brushtail possums, Trichosurus vulpecula, with Bacille Calmette-Guerin induces T lymphocytes that reduce Mycobacterium bovis replication in alveolar macrophages via a contact-dependent/nitric oxide-independent mechanism

scientific article

Vaccination of cattle with Danish and Pasteur strains of Mycobacterium bovis BCG induce different levels of IFNgamma post-vaccination, but induce similar levels of protection against bovine tuberculosis

scientific article published on 19 April 2007

Vaccination of cattle with Mycobacterium bovis BCG by a combination of systemic and oral routes

scientific article published on 24 April 2008

Vaccination of cattle with Mycobacterium bovis culture filtrate proteins and CpG oligodeoxynucleotides induces protection against bovine tuberculosis

scientific article published on 01 June 2005

Vaccination of cattle with Mycobacterium bovis culture filtrate proteins and interleukin-2 for protection against bovine tuberculosis

scientific article

Vaccination of cattle with a CpG oligodeoxynucleotide-formulated mycobacterial protein vaccine and Mycobacterium bovis BCG induces levels of protection against bovine tuberculosis superior to those induced by vaccination with BCG alone.

scientific article

Vaccination of cattle with a high dose of BCG vaccine 3 weeks after experimental infection with Mycobacterium bovis increased the inflammatory response, but not tuberculous pathology.

scientific article published on 27 May 2016

Vaccination of cattle with a methanogen protein produces specific antibodies in the saliva which are stable in the rumen

scientific article published on 27 February 2015

Vaccination with DNA vaccines encoding MPB70 or MPB83 or a MPB70 DNA prime-protein boost does not protect cattle against bovine tuberculosis

scientific article published on 01 January 2003

Vaccines against bovine mastitis in the New Zealand context: what is the best way forward?

scientific article published on June 2009

Vaccines displaying mycobacterial proteins on biopolyester beads stimulate cellular immunity and induce protection against tuberculosis

scientific article published on 9 November 2011

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