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List of works by Ján Lehotský

Age-associated changes in Ca(2+)-ATPase and oxidative damage in sarcoplasmic reticulum of rat heart

scientific article published on 08 August 2012

Alteration in rabbit brain endoplasmic reticulum Ca2+ transport by free oxygen radicals in vitro.

scientific article

Alterations induced by ischemic preconditioning on secretory pathways Ca2+-ATPase (SPCA) gene expression and oxidative damage after global cerebral ischemia/reperfusion in rats.

scientific article published on 14 March 2009

Analysis of genetic polymorphisms of brain-derived neurotrophic factor and methylenetetrahydrofolate reductase in depressed patients in a Slovak (Caucasian) population.

scientific article published in December 2012

ApaI, BsmI and TaqI VDR gene polymorphisms in association with multiple sclerosis in Slovaks

scientific article published on 23 June 2016

Association of EGF, IGFBP-3 and TP53 Gene Polymorphisms with Major Depressive Disorder in Slovak Population

scientific article published on September 2016

Association of Induced Hyperhomocysteinemia with Alzheimer's Disease-Like Neurodegeneration in Rat Cortical Neurons After Global Ischemia-Reperfusion Injury

scientific article published on 12 July 2018

Change in fluidity of brain endoplasmic reticulum membranes by oxygen free radicals: a protective effect of stobadine, alpha-tocopherol acetate, and butylated hydroxytoluene

scientific article published on 01 July 1995

Combination of hyperhomocysteinemia and ischemic tolerance in experimental model of global ischemia in rats

scientific article published in December 2015

Conformational changes of (Ca2+-Mg2+)-ATPase of erythrocyte plasma membrane caused by calmodulin and phosphatidylserine as revealed by circular dichroism and fluorescence studies

scientific article published in 1989

Control of Ca2+ homeostasis in neuronal cells.

scientific article published on June 1996

Cross-talk of intracellular calcium stores in the response to neuronal ischemia and ischemic tolerance.

scientific article published on January 2009

Denervation induced changes in level of Ca-antagonists binding cytosolic protein from white skeletal muscle

scientific article published on 01 February 1991

Differential expression of doublecortin and microglial markers in the rat brain following fractionated irradiation.

scientific article published on 9 December 2014

Distribution of Ca(2+)-modulating proteins in sarcoplasmic reticulum membranes after denervation

scientific article published on 01 August 1993

Effect of Fractionated Irradiation on the Hippocampus in an Experimental Model.

scientific article published in January 2015

Effect of Hyperhomocysteinemia on Redox Balance and Redox Defence Enzymes in Ischemia-Reperfusion Injury and/or After Ischemic Preconditioning in Rats

scientific article published on 16 February 2017

Effect of Long-Term Normobaric Hyperoxia on Oxidative Stress in Mitochondria of the Guinea Pig Brain

scientific article published on April 19, 2011

Effect of Methionine Diet on Metabolic and Histopathological Changes of Rat Hippocampus

scientific article published on 10 December 2019

Effect of Methionine Diet on Time-Related Metabolic and Histopathological Changes of Rat Hippocampus in the Model of Global Brain Ischemia

scientific article published on 30 July 2020

Effect of aging on formation of reactive oxygen species by mitochondria of rat heart.

scientific article

Effect of aging on the expression of intracellular Ca(2+) transport proteins in a rat heart.

scientific article published on 15 February 2007

Effect of homocysteine on survival of human glial cells

scientific article

Effect of normobaric oxygen treatment on oxidative stress and enzyme activities in guinea pig heart.

scientific article published in June 2012

Effect of whole-brain irradiation on the specific brain regions in a rat model: Metabolic and histopathological changes

scientific article published on 19 March 2017

Effects of dimethyl sulfoxide and polycationic neomycin on stimulation of purified plasma membrane Ca(2+)-pump by negatively charged phospholipids.

scientific article published in December 1992

Effects of fractionated whole-brain irradiation on cellular composition and cognitive function in the rat brain

scientific article published on 8 January 2018

Effects of long-term oxygen treatment on alpha-ketoglutarate dehydrogenase activity and oxidative modifications in mitochondria of the guinea pig heart.

scientific article

Effects of mild hyperhomocysteinemia on electron transport chain complexes, oxidative stress, and protein expression in rat cardiac mitochondria.

scientific article published on 15 October 2015

Fe2+-induced inhibition of gerbil forebrain microsomal Ca2+-ATPase: effect of stobadine, glutathione and combination of both antioxidants.

scientific article published in March 1998

FokI vitamin D receptor gene polymorphism in association with multiple sclerosis risk and disability progression in Slovaks

scientific article

Free radical-induced protein modification and inhibition of Ca2+-ATPase of cardiac sarcoplasmic reticulum.

scientific article published in June 2003

Genetic variants in interleukin 7 receptor α chain (IL-7Ra) are associated with multiple sclerosis risk and disability progression in Central European Slovak population.

scientific article published on 18 March 2015

Histone Hyperacetylation as a Response to Global Brain Ischemia Associated with Hyperhomocysteinemia in Rats

scientific article published on 12 October 2018

Hyperhomocysteinemia as a risk factor for the neuronal system disorders

scientific article published on February 2014

Intracellular Ca2+ store from rabbit brain: kinetic aspects of Ca(2+)-stimulated ATPase

scientific article published on 01 August 1994

Intracellular and molecular aspects of Ca(2+)-mediated signal transduction in neuronal cells.

scientific article published on August 1996

Intracellular signaling MAPK pathway after cerebral ischemia-reperfusion injury.

scientific article published on 20 March 2012

Ion transport systems as targets of free radicals during ischemia reperfusion injury.

scientific article published in March 2002

Ionizing radiation induced long-term alterations in the adult rat rostral migratory stream.

scientific article published on 27 September 2013

Iron-induced lipid peroxidation and protein modification in endoplasmic reticulum membranes. Protection by stobadine

scientific article published on 01 May 2000

Ischemia-induced inhibition of active calcium transport into gerbil brain microsomes: effect of anesthetics and models of ischemia.

scientific article published in February 2000

Ischemia/Reperfusion-induced oxidative stress causes structural changes of brain membrane proteins and lipids.

scientific article published in December 2001

Ischemic tolerance: the mechanisms of neuroprotective strategy.

scientific article published on December 2009

Long-term alterations of cell population in the adult rat forebrain following the exposure to fractionated doses of ionizing radiation.

scientific article published on March 2013

Mechanisms involved in the ischemic tolerance in brain: effect of the homocysteine.

scientific article published on 07 September 2014

Membrane ion transport systems during oxidative stress in rodent brain: protective effect of stobadine and other antioxidants

scientific article published on 01 January 1999

Metabolic and histopathological changes in the brain and plasma of rats exposed to fractionated whole-brain irradiation

scientific article published on 17 December 2018

Molecular analysis of endoplasmic reticulum stress response after global forebrain ischemia/reperfusion in rats: effect of neuroprotectant simvastatin.

scientific article published on 19 September 2008

Molecular pathways of endoplasmic reticulum dysfunctions: possible cause of cell death in the nervous system.

scientific article

Myofibrillar Ca2+-stimulated Mg2+-ATPase from chronically ischemic canine heart

scientific article published on 01 March 2002

NMR metabolomic study of blood plasma in ischemic and ischemically preconditioned rats: an increased level of ketone bodies and decreased content of glycolytic products 24 h after global cerebral ischemia

scientific article published on 11 May 2018

Neuroprotection exerted by ischemic preconditioning in rat hippocampus involves extracellular signal receptor changes.

scientific article

Oxidative modifications of cardiac mitochondria and inhibition of cytochrome c oxidase activity by 4-hydroxynonenal.

scientific article published in January 2007

Plasma membrane Ca(2+)-pump functional specialization in the brain. Complex of isoform expression and regulation by effectors.

scientific article published on June 1995

Proliferation activity in the adult rat brain following exposure to ionizing radiation.

scientific article published in January 2013

Properties of skeletal muscle sarcoplasmic reticulum membranes prepared in the presence of dithiothreitol

scientific article published on October 1, 1992

Proteomic analysis of mitochondrial proteins in the guinea pig heart following long-term normobaric hyperoxia

scientific article published on 21 April 2017

Radiation-induced long-term alterations in hippocampus under experimental conditions.

scientific article

Relationship between antioxidant potential and oxidative damage to lipids, proteins and DNA in aged rats

scientific article published on 06 November 2006

Response of secretory pathways Ca(2+) ATPase gene expression to hyperhomocysteinemia and/or ischemic preconditioning in rat cerebral cortex and hippocampus

scientific article

Role of Homocysteine in the Ischemic Stroke and Development of Ischemic Tolerance

scientific article

Role of sarcoplasmic reticulum in the contractile dysfunction during myocardial ischaemia and reperfusion

scientific article published on 01 January 1997

Stimulation of the catalytic cycle of the Ca2+ pump of porcine plasma-membranes by negatively charged phospholipids

scientific article published on 01 March 1992

Synaptosomal Na, K-ATPase during forebrain ischemia in Mongolian gerbils

scientific article published on 01 September 1996

The Effect of Aging on Mitochondrial Complex I and the Extent of Oxidative Stress in the Rat Brain Cortex.

scientific article published on 9 May 2016

The HLA-DRB1 and HLA-DQB1 alleles are associated with multiple sclerosis disability progression in Slovak population

scientific article published on 5 April 2018

The Molecular and Cellular Effect of Homocysteine Metabolism Imbalance on Human Health

scientific article

The age at onset in Multiple Sclerosis is associated with patient's prognosis

scientific article published in January 2017

The association of HLA-DRB1 and HLA-DQB1 alleles with genetic susceptibility to multiple sclerosis in the Slovak population.

scientific article published on 8 January 2016

Time course of ischemia/reperfusion-induced oxidative modification of neural proteins in rat forebrain.

scientific article published in December 2004

Time course of peripheral oxidative stress as consequence of global ischaemic brain injury in rats

scientific article published on 04 December 2007

Time-related metabolomics study in the rat plasma after global cerebral ischemia and reperfusion: Effect of ischemic preconditioning

scientific article published on 14 July 2020

Why mitochondria are excellent targets for cancer therapy.

scientific article published on January 2012

[Interaction of cholesterol and sphingomyelins in membranes of the sarcotubular system after denervation]

scientific article published on 01 September 1994

[Membrane-associated acetylcholinesterase in the sarcotubular system of skeletal muscles]

scientific article published on 01 June 1989

[Neurochemical changes associated with ischemic-reperfusion injury of the CNS]

scientific article published on 01 July 1998

[The Ca(2+)-pump in erythrocytes is inhibited by glucose: a possible role in the pathogenesis of chronic complications in diabetes]

scientific article published on 01 March 1994

[The effect of ischemia and ischemia-reperfusion on ion transport systems].

scientific article

p-ERK involvement in the neuroprotection exerted by ischemic preconditioning in rat hippocampus subjected to four vessel occlusion

scientific article published in December 2014

sRage plasma level in association with multiple sclerosis risk in Slovak population.

scientific article published on 12 June 2015