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List of works by Michael Tainsky

A role for manganese superoxide dismutase in apoptosis after photosensitization.

scientific article published in July 2005

Activation of ribosomal protein S2 gene expression in a hamster model of chemically induced oral carcinogenesis.

scientific article

Aflatoxin B1-induced immortalization of cultured skin fibroblasts from a patient with Li-Fraumeni syndrome.

scientific article published on January 1995

Alteration of homeobox gene expression by N-ras transformation of PA-1 human teratocarcinoma cells ⬇️

scientific article published on July 1, 1991

An activated rasN gene: detected in late but not early passage human PA1 teratocarcinoma cells.

scientific article published in August 1984

An alternatively spliced mRNA from the AP-2 gene encodes a negative regulator of transcriptional activation by AP-2

scientific article

Analysis of the expression of human tumor antigens in ovarian cancer tissues

scientific article

Analysis of the virogenes related to the rhesus monkey endogenous type C retrovirus in monkeys and apes.

scientific article

Assessing the functional bias of commercial microarrays using the onto-compare database.

scientific article published on March 2003

Autoantibody approach for serum-based detection of head and neck cancer.

scientific article

Breast cancer and other neoplasms in women with neurofibromatosis type 1: a retrospective review of cases in the Detroit metropolitan area

article

Breast cancer risk and germline genomic profiling of women with neurofibromatosis type 1 who developed breast cancer.

scientific article published on 10 September 2017

CREG1 enhances p16INK4a-induced cellular senescence ⬇️

scientific article published on February 1, 2011

Cancer biomarker discovery: speed-bumps and tire shredders

scientific article published on 01 January 2010

Characterization of human transforming genes from chemically transformed, teratocarcinoma, and pancreatic carcinoma cell lines.

scientific article

Cloning and characterization of the Drosophila homologue of the AP-2 transcription factor.

scientific article published in October 1998

Combinatorial therapeutic targeting of BMP2 and MEK-ERK pathways in NF1-associated malignant peripheral nerve sheath tumors

scientific article published on 3 August 2016

Communication and decision-making about seeking inherited cancer risk information: findings from female survivor-relative focus groups.

scientific article published in March 2006

Concerns and recommendations regarding inherited cancer risk: the perspectives of survivors and female relatives.

scientific article published in January 2007

Control of angiogenesis in fibroblasts by p53 regulation of thrombospondin-1

scientific article published on 01 September 1994

Correlation between Ha-ras gene amplification and spontaneous metastasis in NIH 3T3 cells transfected with genomic DNA from human skin cancers.

scientific article published on May 1989

Critical pathways in cellular senescence and immortalization revealed by gene expression profiling.

scientific article published on 18 August 2008

De novo ceramide accumulation due to inhibition of its conversion to complex sphingolipids in apoptotic photosensitized cells.

scientific article published on 12 March 2004

Defective G2 checkpoint function in cells from individuals with familial cancer syndromes

scientific article published on 01 April 1995

Diagnostic markers of ovarian cancer by high-throughput antigen cloning and detection on arrays.

scientific article published in January 2006

Diverse system stresses: common mechanisms of chromosome fragmentation.

scientific article published on 30 June 2011

Docetaxel associated pathways in cisplatin resistant head and neck squamous cell carcinoma: a pilot study.

scientific article published on November 2005

EGF receptor activity and mitogenic response of Balb/3T3 cells expressing Ras and Myc oncogenes. EGF receptor activity in oncogene transformed cells

scientific article published on 01 September 1992

Elevated expression of the ribosomal protein S2 gene in human tumors

scientific article published on January 1, 1992

Enhanced Krev-1 Expression Inhibits the Growth of Pancreatic Adenocarcinoma Cells ⬇️

scientific article published on May 1, 1998

Epigenetic Silencing of IRF7 and/or IRF5 in Lung Cancer Cells Leads to Increased Sensitivity to Oncolytic Viruses ⬇️

scientific article published on December 14, 2011

Epigenetic silencing of multiple interferon pathway genes after cellular immortalization.

scientific article

Ethnic differences in survival among women with ovarian carcinoma.

scientific article

Evaluation of paraneoplastic antigens reveals TRIM21 autoantibodies as biomarker for early detection of ovarian cancer in combination with autoantibodies to NY-ESO-1 and TP53

scientific article published on 01 January 2020

Evidence that tumor necrosis factor-related apoptosis-inducing ligand induction by 5-Aza-2'-deoxycytidine sensitizes human breast cancer cells to adriamycin.

scientific article published on February 2007

Expression profiling identifies three pathways altered in cellular immortalization: interferon, cell cycle, and cytoskeleton.

scientific article published on September 2006

FANCM, RAD1, CHEK1 and TP53I3 act as BRCA-like tumor suppressors and are mutated in hereditary ovarian cancer

scientific article published on 09 May 2019

Functional characterization of the interacting domains of the positive coactivator PC4 with the transcription factor AP-2alpha.

scientific article

Genetic analysis of childhood sarcoma

scientific article published on 01 January 1989

Genomic and proteomic biomarkers for cancer: a multitude of opportunities.

scientific article published on 04 May 2009

Genomic instability due to germline p53 mutations drives preneoplastic Progression toward cancer in human cells ⬇️

scientific article published on March 1, 1995

Germ line p53 mutations in a familial syndrome of breast cancer, sarcomas, and other neoplasms

scientific article (publication date: 30 November 1990)

Germline and Somatic NF1 Alterations Are Linked to Increased HER2 Expression in Breast Cancer

scientific article published on 13 August 2018

Higher miRNA Tolerance in Immortal Li-Fraumeni Fibroblasts with Abrogated Interferon Signaling Pathway ⬇️

scientific article published on January 1, 2011

Immunotheranostics: breaking tolerance in immunotherapy using tumor autoantigens identified on protein microarrays.

scientific article

In vitro growth characteristics of embryo fibroblasts isolated from p53-deficient mice

scientific article published in September 1993

Isolation and Characterization of an Endogenous Type C Virus of Rhesus Monkeys ⬇️

scientific article published on May 25, 1979

Isolation and characterization of a breast progenitor epithelial cell line with robust DNA damage responses.

scientific article published on 16 March 2006

Loss of AP-2 Results in Up-regulation ofMCAM/MUC18 and an Increase in Tumor Growth and Metastasis of Human Melanoma Cells ⬇️

scientific article published on June 26, 1998

Loss of AP-2 results in downregulation of c-KIT and enhancement of melanoma tumorigenicity and metastasis.

scientific article

Mechanism of activation of human ras genes cloned from a gastric adenocarcinoma and a pancreatic carcinoma cell line

scientific article published on 01 September 1986

Met proto-oncogene product is overexpressed in tumors of p53-deficient mice and tumors of Li-Fraumeni patients.

scientific article published on May 1995

Microsatellite alterations in african americans with head and neck cancer.

scientific article published in September 2004

Microtubule deacetylases, SirT2 and HDAC6, in the nervous system

scientific journal article

Modulation of differentiation in PA-1 human teratocarcinoma cells after N-ras oncogene-induced tumorigenicity

scientific article published on September 1, 1991

Molecular approaches to prevention and therapy of aerodigestive tract cancers

scientific article published on January 1, 1992

Molecular cloning of a new transforming gene from a chemically transformed human cell line.

scientific article published in September 1984

Molecular cloning of the Mason-Pfizer monkey virus genome: biological characterization of genome length clones and molecular comparisons to other retroviruses.

scientific article

Molecular phenotyping of head and neck cancer.

scientific article published on January 1995

Molecular targets for emerging anti-tumor therapies for neurofibromatosis type 1.

scientific article published on 28 April 2006

Multianalyte tests for the early detection of cancer: speedbumps and barriers.

scientific article published on 10 July 2007

Mutations in SIRT2 deacetylase which regulate enzymatic activity but not its interaction with HDAC6 and tubulin.

scientific article

Myeloperoxidase and free iron levels: potential biomarkers for early detection and prognosis of ovarian cancer.

scientific article

N-ras oncogene causes AP-2 transcriptional self-interference, which leads to transformation.

scientific article

Non-traditional immunogens and their application to immunotherapy.

scientific article published on February 2008

Oncogene Mutation Survey in MPNST Cell Lines Enhances the Dominant Role of Hyperactive Ras in NF1 Associated Pro-Survival and Malignancy ⬇️

scientific article published on January 18, 2012

PA-1, a human cell model for multistage carcinogenesis: oncogenes and other factors.

scientific article published on September 1988

Paraneoplastic antigens as biomarkers for early diagnosis of ovarian cancer

scientific article

Pathways to implementation of serum proteomics for cancer

scientific article published on 01 September 2007

PolyADP-ribose polymerase is a coactivator for AP-2-mediated transcriptional activation.

scientific article published on February 1999

Preface

scientific article published on 01 March 2015

Preparation of High-Molecular-Weight DNA for Use in DNA Transfection: Secondary Transfections for Cloning Active Genes by Direct Phenotypic Selection

scientific article published on January 1, 1991

Programming gene expression in developing epidermis ⬇️

scientific article published on September 1, 1994

Reanalysis of BRCA1/2 negative high risk ovarian cancer patients reveals novel germline risk loci and insights into missing heritability.

scientific article

Regulation of the in vitro synthesis of the α-peptide of β-galactosidase directed by a restriction fragment of the lactose operon ⬇️

scientific article published on April 14, 1978

Risk perception and cancer worries in families at increased risk of familial breast/ovarian cancer.

scientific article published on August 2008

Role for human SIRT2 NAD-dependent deacetylase activity in control of mitotic exit in the cell cycle

scientific article

Serum folate receptor α (sFR) in ovarian cancer diagnosis and surveillance

scientific article published on 13 February 2019

Serum prognostic biomarkers in head and neck cancer patients.

scientific article

Sphingomyelin synthase 1 suppresses ceramide production and apoptosis post-photodamage

scientific article

Stat1 expression is not sufficient to regulate the interferon signaling pathway in cellular immortalization.

scientific article published on January 2006

Stochastic cancer progression driven by non-clonal chromosome aberrations.

scientific article

Structure and function of the HOX A1 human homeobox gene cDNA

scientific article

Suppression of proliferation of two independent NF1 malignant peripheral nerve sheath tumor cell lines by the pan-ErbB inhibitor CI-1033.

scientific article published on 07 December 2008

Telomerase activity during spontaneous immortalization of Li-Fraumeni syndrome skin fibroblasts ⬇️

scientific article published on August 13, 1998

Telomere dysfunction and chromothripsis

scientific article published on 9 February 2016

The H-ras oncogene regulates expression of 70- and 45-kDa cell-surface molecules whose expression correlates with tumor-cell immunogenicity

scientific article published on September 9, 1992

The effect of retinoic acid on chemosensitivity of PA-1 human teratocarcinoma cells and its modulation by an activated N-ras oncogene

scientific article published on June 19, 1992

The p53 tumor suppressor gene inhibits angiogenesis by stimulating the production of thrombospondin.

scientific article published on January 1994

The role of neurofibromin in N-Ras mediated AP-1 regulation in malignant peripheral nerve sheath tumors ⬇️

scientific article published on August 1, 2010

Transfection of activated c-H-rasEJ/pSV2neo or pSV2neo genes into rat mammary cells: rapid stimulation of clonal diversification of spontaneous metastatic and cell-surface properties

scientific article published on June 1, 1992

Tumor autoantibodies as biomarkers for predicting ovarian cancer recurrence.

scientific article published on January 2012

Usage of cancer associated autoantibodies in the detection of disease

scientific article published on January 2010

Utility of paraneoplastic antigens as biomarkers for surveillance and prediction of recurrence in ovarian cancer

scientific article published on 3 November 2017

Utilizing iVariantGuide for Variant Assessment of Next-Generation Sequencing

scientific article published on 12 February 2019

Visualization of the timing of gene amplification during multistep head and neck tumorigenesis

scientific article published on 01 November 2000

Wild-type p53 restores cell cycle control and inhibits gene amplification in cells with mutant p53 alleles.

scientific article published in September 1992

[AP-2: a nuclear effector of malignant transformation by ras oncogene]

scientific article published on 01 January 1993

drp, a novel protein expressed at high cell density but not during growth arrest.

scientific article published on May 1998

p53 and retinoid chemoprevention of oral carcinogenesis.

scientific article published on January 1995

pZ402, an improved SV40-based shuttle vector containing a T-antigen mutant unable to interact with wild-type p53 ⬇️

scientific article published on May 12, 1998

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