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List of works by Michelle L. Block

A pivotal role of matrix metalloproteinase-3 activity in dopaminergic neuronal degeneration via microglial activation

scientific article published on 20 November 2006

Aggregated alpha-synuclein activates microglia: a process leading to disease progression in Parkinson's disease

scientific article published in April 2005

Air pollution & the brain: Subchronic diesel exhaust exposure causes neuroinflammation and elevates early markers of neurodegenerative disease ⬇️

scientific article published on August 24, 2011

Air pollution: mechanisms of neuroinflammation and CNS disease

scientific article

Atypical microglial response to biodiesel exhaust in healthy and hypertensive rats.

scientific article

Chronic Apocynin Treatment Attenuates Beta Amyloid Plaque Size and Microglial Number in hAPP(751)SL Mice ⬇️

scientific article published on May 31, 2011

Curcumin protects dopaminergic neuron against LPS induced neurotoxicity in primary rat neuron/glia culture.

scientific article published on 27 March 2008

Diesel Exhaust Activates and Primes Microglia: Air Pollution, Neuroinflammation, and Regulation of Dopaminergic Neurotoxicity ⬇️

scientific article published on May 11, 2011

Diesel exhaust impairs TREM2 to dysregulate neuroinflammation

scientific article published on 22 November 2020

Diesel exhaust particles induce oxidative stress, proinflammatory signaling, and P-glycoprotein up-regulation at the blood-brain barrier

scientific article

Femtomolar concentrations of dextromethorphan protect mesencephalic dopaminergic neurons from inflammatory damage

Formyl-methionyl-leucyl-phenylalanine-induced dopaminergic neurotoxicity via microglial activation: a mediator between peripheral infection and neurodegeneration?

scientific article published on May 2008

Histone deacetylase inhibitors up-regulate astrocyte GDNF and BDNF gene transcription and protect dopaminergic neurons

scientific article published on 09 July 2008

In Vitro Models for Neuroelectrodes: A Paradigm for Studying Tissue–Materials Interactions in the Brain

In vitro model of glial scarring around neuroelectrodes chronically implanted in the CNS.

scientific article published on 13 July 2006

Interactive role of the toll-like receptor 4 and reactive oxygen species in LPS-induced microglia activation.

scientific article published in October 2005

Interleukin-10 protects lipopolysaccharide-induced neurotoxicity in primary midbrain cultures by inhibiting the function of NADPH oxidase

scientific article published on 28 June 2006

Loss of NF-κB p50 function synergistically augments microglial priming in the middle-aged brain

scholarly article by Thomas Taetzsch et al published 12 March 2019 in Journal of Neuroinflammation

MAC1 mediates LPS-induced production of superoxide by microglia: the role of pattern recognition receptors in dopaminergic neurotoxicity

scientific article published on 01 October 2007

Macrophage antigen complex-1 mediates reactive microgliosis and progressive dopaminergic neurodegeneration in the MPTP model of Parkinson's disease

scientific article

Mentoring: An Evolving Relationship

scientific article published in April 2017

Microglia and inflammation-mediated neurodegeneration: multiple triggers with a common mechanism

scientific article (publication date: June 2005)

Microglia-mediated neurotoxicity: uncovering the molecular mechanisms

scientific article (publication date: 2007)

Microglial NADPH oxidase is a novel target for femtomolar neuroprotection against oxidative stress.

scientific article published in April 2005

Microglial NADPH oxidase mediates leucine enkephalin dopaminergic neuroprotection

scientific article published in August 2005

Microglial activation and chronic neurodegeneration

scientific article published on October 2010

Microglial activation decreases retention of the protease inhibitor saquinavir: implications for HIV treatment ⬇️

scientific article published on May 4, 2013

Microglial priming through the lung-brain axis: the role of air pollution-induced circulating factors.

scientific article published on 10 February 2016

Morphinan neuroprotection: new insight into the therapy of neurodegeneration.

scientific article

NADPH oxidase as a therapeutic target in Alzheimer's disease

scientific article

NADPH oxidase inhibitor DPI is neuroprotective at femtomolar concentrations through inhibition of microglia over-activation.

scientific article published in January 2007

NADPH oxidase mediates lipopolysaccharide-induced neurotoxicity and proinflammatory gene expression in activated microglia.

scientific article published on 24 October 2003

NOS1-derived nitric oxide promotes NF-κB transcriptional activity through inhibition of suppressor of cytokine signaling-1.

scientific article

Neuroinflammation, hyperphosphorylated tau, diffuse amyloid plaques, and down-regulation of the cellular prion protein in air pollution exposed children and young adults

scientific article

Neuroinflammation: modulating mighty microglia

scientific article published in December 2014

Outdoor Ambient Air Pollution and Neurodegenerative Diseases: the Neuroinflammation Hypothesis

scientific article

Particulate matter, oxidative stress and neurotoxicity.

scientific article published on 04 January 2008

Pesticides, Microglial NOX2, and Parkinson's Disease ⬇️

scientific article published on January 24, 2013

Pituitary adenylate cyclase-activating polypeptide (PACAP) 38 and PACAP4-6 are neuroprotective through inhibition of NADPH oxidase: potent regulators of microglia-mediated oxidative stress.

scientific article published on 4 August 2006

Protective effect of dextromethorphan against endotoxic shock in mice.

scientific article published on 26 November 2004

Reactive microgliosis participates in MPP+-induced dopaminergic neurodegeneration: role of 67 kDa laminin receptor.

scientific article published in May 2006

Reactive microgliosis: extracellular micro-calpain and microglia-mediated dopaminergic neurotoxicity.

scientific article

Redox regulation of NF-κB p50 and M1 polarization in microglia

scientific article

Retinoic acid attenuates beta-amyloid deposition and rescues memory deficits in an Alzheimer's disease transgenic mouse model.

scientific article

Role of phagocyte oxidase in UVA-induced oxidative stress and apoptosis in keratinocytes

scientific article published in September 2005

Systemic LPS causes chronic neuroinflammation and progressive neurodegeneration

scientific article

Targeting microglia-mediated neurotoxicity: the potential of NOX2 inhibitors ⬇️

scientific article published on May 13, 2012

Ten years of Nature Reviews Neuroscience: insights from the highly cited

scientific article

The outdoor air pollution and brain health workshop

journal article published in 2012

The role of MAC1 in diesel exhaust particle-induced microglial activation and loss of dopaminergic neuron function

scientific article published on 2 April 2013

The role of microglia in paraquat-induced dopaminergic neurotoxicity

scientific article published in May 2005

beta-Chemokine production by neural and glial progenitor cells is enhanced by HIV-1 Tat: effects on microglial migration.

scientific article

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