Search filters

List of works by Philipp Tinnefeld

'Self-healing' dyes: intramolecular stabilization of organic fluorophores

scientific article published on 27 April 2012

A DNA Walker as a Fluorescence Signal Amplifier.

scientific article published on 28 July 2017

A Reducing and Oxidizing System Minimizes Photobleaching and Blinking of Fluorescent Dyes

scientific article (publication date: 7 July 2008)

A Two-Component Regulatory System Impacts Extracellular Membrane-Derived Vesicle Production in Group A Streptococcus

scientific article (publication date: November 2016)

A high sensitive and specific QDs FRET bioprobe for MNase

scientific article published on 14 October 2008

A new reporter design based on DNA origami nanostructures for quantification of short oligonucleotides using microbeads

scientific article published on 18 March 2019

A starting point for fluorescence-based single-molecule measurements in biomolecular research.

scientific article published on 30 September 2014

A structurally variable hinged tetrahedron framework from DNA origami

scientific article published on 18 September 2011

Absolute Arrangement of Subunits in Cytoskeletal Septin Filaments in Cells Measured by Fluorescence Microscopy.

scientific article published on 8 May 2015

Addressable nanoantennas with cleared hotspots for single-molecule detection on a portable smartphone microscope

scientific article published on 11 February 2021

Advanced markers and labels for life science and biomedical applications

scientific article published on 01 June 2011

Antibunching in the Emission of a Single Tetrachromophoric Dendritic System

scientific article published in December 2002

Application of multiline two-photon microscopy to functional in vivo imaging

scientific article published on 26 January 2006

Axial Colocalization of Single Molecules with Nanometer Accuracy Using Metal-Induced Energy Transfer.

scientific article published on 21 March 2018

Benchmarking Smartphone Fluorescence-Based Microscopy with DNA Origami Nanobeads: Reducing the Gap toward Single-Molecule Sensitivity

scientific article published on 09 January 2019

Branching Out of Single-Molecule Fluorescence Spectroscopy: Challenges for Chemistry and Influence on Biology

Branching out of single-molecule fluorescence spectroscopy: challenges for chemistry and influence on biology

scientific article

Breaking the concentration limit of optical single-molecule detection.

scientific article published on 10 September 2013

Broad host range vectors for expression of proteins with (Twin-) Strep-tag, His-tag and engineered, export optimized yellow fluorescent protein

scientific article published on May 20, 2013

Broadband Fluorescence Enhancement with Self-Assembled Silver Nanoparticle Optical Antennas

scientific article

Carbocyanine dyes as efficient reversible single-molecule optical switch

scientific article

Choosing dyes for cw-STED nanoscopy using self-assembled nanorulers

scientific article published on 6 March 2014

Cohesin-dockerin code in cellulosomal dual binding modes and its allosteric regulation by proline isomerization

scientific article

Confocal Fluorescence Lifetime Imaging Microscopy (FLIM) at the Single Molecule Level

Confocal Fluorescence Lifetime Imaging Microscopy (FLIM) at the Single Molecule Level

Controlled reduction of photobleaching in DNA origami-gold nanoparticle hybrids

scientific article published on 4 April 2014

Controlling the fluorescence of ordinary oxazine dyes for single-molecule switching and superresolution microscopy

scholarly article

Correlated movement and bending of nucleic acid structures visualized by multicolor single-molecule spectroscopy

scientific article

Counting fluorescent dye molecules on DNA origami by means of photon statistics.

scientific article published on 24 June 2013

Cover Picture: Branching Out of Single-Molecule Fluorescence Spectroscopy: Challenges for Chemistry and Influence on Biology (Angew. Chem. Int. Ed. 18/2005)

Cover Picture: DNA Origami Seesaws as Comparative Binding Assay (ChemBioChem 12/2016)

scientific article published on 16 June 2016

DNA Origami Nanoantennas with over 5000-fold Fluorescence Enhancement and Single-Molecule Detection at 25 μM

scientific article published on 05 November 2015

DNA Origami Seesaws as Comparative Binding Assay

scientific article published on April 2016

DNA origami as a nanoscopic ruler for super-resolution microscopy

scientific article published in January 2009

DNA origami as biocompatible surface to match single-molecule and ensemble experiments

scientific article published on April 20, 2012

DNA origami nanopillars as standards for three-dimensional superresolution microscopy.

scientific article published on 5 February 2013

DNA origami-based single-molecule force spectroscopy elucidates RNA Polymerase III pre-initiation complex stability

scientific article published on 05 June 2020

DNA origami-based standards for quantitative fluorescence microscopy.

scientific article

DNA-Based Molecular Wires: Multiple Emission Pathways of Individual Constructs

scientific article published on 01 December 2006

DNA-templated nanoantennas for single-molecule detection at elevated concentrations.

scientific article published in June 2013

Design of molecular photonic wires based on multistep electronic excitation transfer

scientific article

Detection of single oxygen molecules opens up new vistas for the investigation of molecular cooperativity in hemocyanins

scientific article published in June 2006

Development of a molecular photonic wire by means of multiparameter single-molecule spectroscopy

Direct Observation of Collective Blinking and Energy Transfer in a Bichromophoric System

Direct observation of abortive initiation and promoter escape within single immobilized transcription complexes.

scientific article

Directing Single-Molecule Emission with DNA Origami-Assembled Optical Antennas

scientific article published on 26 August 2019

Dissecting and reducing the heterogeneity of excited-state energy transport in DNA-based photonic wires

scientific article

Distance control in-between plasmonic nanoparticles via biological and polymeric spacers

scholarly article by Xiang Yu et al published October 2013 in Nano Today

Distance dependence of single-fluorophore quenching by gold nanoparticles studied on DNA origami

scientific article

Ein System aus Reduktions‐ und Oxidationsmittel verringert Photobleichen und Blinken von Fluoreszenzfarbstoffen

article

Engineered fluorescent proteins illuminate the bacterial periplasm

scientific article

Enhancing single-molecule fluorescence with nanophotonics

scientific article

Enzymatic characterization of recombinant nitrate reductase expressed and purified from Neurospora crassa

scientific article

Enzymatic polymerization of poly(thymine) for the synthesis of copper nanoparticles with tunable size and their application in enzyme sensing.

scientific article published in May 2015

Eukaryotic and archaeal TBP and TFB/TF(II)B follow different promoter DNA bending pathways

scientific article

Fluorescence and super-resolution standards based on DNA origami

scientific article published on 01 December 2012

Fluorescence microscopy with 6 nm resolution on DNA origami

scientific article published on 04 June 2014

Fluorescence of Single Molecules in Polymer Films: Sensitivity of Blinking to Local Environment

scientific article published in June 2007

Fluorescent Nanodiamond-Gold Hybrid Particles for Multimodal Optical and Electron Microscopy Cellular Imaging

scientific article published on 15 September 2016

Fluorescent proteins for single-molecule fluorescence applications

scientific article

Fluorophore photostability and saturation in the hotspot of DNA origami nanoantennas

scientific article published on 05 February 2020

Fluorophores: Single-Molecule STED Microscopy with Photostable Organic Fluorophores (Small 13/2010)

Geminate recombination as a photoprotection mechanism for fluorescent dyes

scientific article published on 08 April 2014

Generation of Recombinant Antibodies against the beta-(1,6)-Branched beta-(1,3)-D-Glucan Schizophyllan from Immunized Mice via Phage Display.

scientific article

Guide-independent DNA cleavage by archaeal Argonaute from Methanocaldococcus jannaschii.

scientific article published on 20 March 2017

High force catch bond mechanism of bacterial adhesion in the human gut

scientific article published on 28 August 2020

High-resolution colocalization of single dye molecules by fluorescence lifetime imaging microscopy.

scientific article

High-resolution colocalization of single molecules within the resolution gap of far-field microscopy

scientific article

Higher-excited-state photophysical pathways in multichromophoric systems revealed by single-molecule fluorescence spectroscopy

scientific article published in November 2004

Impact of Cyanine Conformational Restraint in the Near-Infrared Range

scientific article published on 10 April 2020

Interchromophoric Interactions Determine the Maximum Brightness Density in DNA Origami Structures

scientific article published on 25 January 2019

Intrinsically resolution enhancing probes for confocal microscopy

scientific article

Linking Single-Molecule Blinking to Chromophore Structure and Redox Potentials

article by Ingo H. Stein et al published 8 December 2011 in ChemPhysChem

Localized direction selective responses in the dendrites of visual interneurons of the fly

scientific article

Make them blink: probes for super-resolution microscopy.

scientific article published on August 2010

Making connections—strategies for single molecule fluorescence biophysics

scientific article published on June 13, 2013

Making ultrasensitive weighing biocompatible by placing the sample within a resonant cantilever

scientific article published in January 2007

Mapping molecules in scanning far-field fluorescence nanoscopy

scientific article

Measuring the number of independent emitters in single-molecule fluorescence images and trajectories using coincident photons.

scientific article

Mechanisms and advancement of antifading agents for fluorescence microscopy and single-molecule spectroscopy

article by Thorben Cordes et al published 2011 in Physical Chemistry Chemical Physics

Molecular Optical Switches and Waveguides

Molecular force spectroscopy with a DNA origami-based nanoscopic force clamp.

scientific article published on October 2016

Multichromophoric Dendrimers as Single-Photon Sources: A Single-Molecule Study

scientific article published in October 2004

Multicolor single-molecule spectroscopy with alternating laser excitation for the investigation of interactions and dynamics

scientific article published in January 2007

Multifunctional Dumbbell-Shaped DNA-Templated Selective Formation of Fluorescent Silver Nanoclusters or Copper Nanoparticles for Sensitive Detection of Biomolecules

scientific article published on 31 December 2015

Multistep Energy Transfer in Single Molecular Photonic Wires

scientific article published on 01 June 2004

Neue Wege in der Einzelmolekül-Fluoreszenzspektroskopie: Herausforderungen für die Chemie und Einfluss auf die Biologie

On the mechanism of Trolox as antiblinking and antibleaching reagent

scientific article published in April 2009

One-pot synthesized aptamer-functionalized CdTe:Zn2+ quantum dots for tumor-targeted fluorescence imaging in vitro and in vivo

scientific article published on 31 May 2013

Optical Nanoantenna for Single Molecule-Based Detection of Zika Virus Nucleic Acids without Molecular Multiplication.

scientific article published on 16 November 2017

Optical Voltage Sensing Using DNA Origami.

scientific article published on 12 February 2018

Optical switches: Key molecules for improved fluorescence imaging and tracking with high optical resolution

Optical switches: key molecules for improved fluorescence imaging and tracking with high optical resolution

Photoinduced electron transfer (PET)-probes for the study of enzyme activity at the ensemble and single molecule level

Photophysical Dynamics of Single Molecules Studied by Spectrally-Resolved Fluorescence Lifetime Imaging Microscopy (SFLIM)

article published in 2001

Photophysics of fluorescent probes for single-molecule biophysics and super-resolution imaging

scientific article

Placing individual molecules in the center of nanoapertures

scientific article published on 17 June 2013

Plasmonics Enhanced Smartphone Fluorescence Microscopy.

scientific article

Precision and accuracy of single-molecule FRET measurements-a multi-laboratory benchmark study

scientific article published on 31 August 2018

Probing Förster Type Energy Pathways in a First Generation Rigid Dendrimer Bearing Two Perylene Imide Chromophores

scientific article published in September 2003

Probing conformational dynamics by photoinduced electron transfer

Programming Light-Harvesting Efficiency Using DNA Origami

scientific article published on 23 February 2016

Protein-protein interactions: Pull-down for single molecules

scientific article published on 01 May 2011

Publisher Correction: Precision and accuracy of single-molecule FRET measurements-a multi-laboratory benchmark study

scholarly article by Björn Hellenkamp published in October 2018

Pulsed Interleaved MINFLUX

scientific article published on 18 December 2020

Quantum yield and excitation rate of single molecules close to metallic nanostructures.

scientific article

Radiative and Nonradiative Rate Fluctuations of Single Colloidal Semiconductor Nanocrystals

scientific article published on 01 March 2006

Repression of RNA polymerase by the archaeo-viral regulator ORF145/RIP.

scientific article

Resolving single-molecule assembled patterns with superresolution blink-microscopy

scientific article published in February 2010

Revealing competitive Forster-type resonance energy-transfer pathways in single bichromophoric molecules

scientific article published on 28 October 2003

Sculpting Light by Arranging Optical Components with DNA Nanostructures.

scientific article

Self-Healing Dyes - Keeping The Promise?

scientific article published on 13 May 2020

Self-Regeneration and Self-Healing in DNA Origami Nanostructures

scientific article published on 23 November 2020

Shifting molecular localization by plasmonic coupling in a single-molecule mirage

scientific article published on 11 January 2017

Simple and aberration-free 4color-STED--multiplexing by transient binding

scientific article published on April 2015

Single-Molecule Approved Surface Passivation

scientific article published on 01 December 2020

Single-Molecule FRET Ruler Based on Rigid DNA Origami Blocks

scientific article published on 9 February 2011

Single-Molecule Fluorescence Meets DNA Origami

scientific article published in January 2012

Single-molecule FRET supports the two-state model of Argonaute action.

scientific article published on 20 December 2013

Single-molecule STED microscopy with photostable organic fluorophores

scientific article

Single-molecule detection: Breaking the concentration barrier

scientific article published on 16 June 2013

Single-molecule fluorescence resonance energy transfer in nanopipets: improving distance resolution and concentration range

scientific article

Single-molecule four-color FRET visualizes energy-transfer paths on DNA origami

scientific article

Single-molecule kinetics and super-resolution microscopy by fluorescence imaging of transient binding on DNA origami

scientific article

Single-molecule photophysics of dark quenchers as non-fluorescent FRET acceptors.

scientific article published in June 2014

Single-molecule photophysics of oxazines on DNA and its application in a FRET switch

scientific article published on 12 March 2009

Single-molecule positioning in zeromode waveguides by DNA origami nanoadapters

scientific article published on 08 May 2014

Single-molecule redox blinking of perylene diimide derivatives in water

scientific article published in February 2010

Site-specific labelling of native mammalian proteins for single-molecule FRET measurements.

scientific article published on 2 February 2018

Spectrally resolved fluorescence lifetime imaging microscopy (SFLIM) and coincidence analysis: new tools to study the organization of biomolecular machines

Strong Plasmonic Enhancement of a Single Peridinin-Chlorophyll a-Protein Complex on DNA Origami-Based Optical Antennas.

scientific article published on 22 January 2018

Subdiffraction-resolution fluorescence imaging with conventional fluorescent probes

scientific article

Substituent Effects on Redox Properties and Photoinduced Electron Transfer in Isoxazolo-Fullerenes

Super-Resolution Imaging Conditions for enhanced Yellow Fluorescent Protein (eYFP) Demonstrated on DNA Origami Nanorulers

scientific article

Super-resolution fluorescence imaging with blink microscopy.

scientific article

Super-resolution imaging of C-type lectin and influenza hemagglutinin nanodomains on plasma membranes using blink microscopy

scientific article published on 3 April 2012

Superresolution microscopy on the basis of engineered dark states

scientific article published on 01 December 2008

Superresolution microscopy with transient binding

scientific article

Synergistic Combination of Unquenching and Plasmonic Fluorescence Enhancement in Fluorogenic Nucleic Acid Hybridization Probes.

scientific article published on 28 September 2017

TFE and Spt4/5 open and close the RNA polymerase clamp during the transcription cycle

scientific article published on 15 March 2016

The 2015 super-resolution microscopy roadmap

Titelbild: Neue Wege in der Einzelmolekül-Fluoreszenzspektroskopie: Herausforderungen für die Chemie und Einfluss auf die Biologie (Angew. Chem. 18/2005)

Toward quantitative fluorescence microscopy with DNA origami nanorulers

scientific article

Toward ultra-stable fluorescent dyes for single-molecule spectroscopy

Towards structural biology with super-resolution microscopy

scientific article published on 01 September 2018

Towards ultra-stable fluorescent dyes for single-molecule spectroscopy

Ultrafast Single-Molecule Fluorescence Measured by Femtosecond Double-Pulse Excitation Photon Antibunching

scientific article published on 08 January 2020

Using DNA origami nanorulers as traceable distance measurement standards and nanoscopic benchmark structures

scientific article published on 29 January 2018

Visual detection of melamine in milk samples based on label-free and labeled gold nanoparticles

scientific article published on 13 May 2011