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List of works by Henry R. Kranzler

5-HTTLPR as a potential moderator of the effects of adverse childhood experiences on risk of antisocial personality disorder

scientific article

5-HTTLPR genotype and daily negative mood moderate the effects of sertraline on drinking intensity

scientific article published on November 12, 2012

5-HTTLPR moderates naltrexone and psychosocial treatment responses in heavy drinking men who have sex with men.

scientific article

A CRHR1 haplotype moderates the effect of adverse childhood experiences on lifetime risk of major depressive episode in African-American women

scientific article published on 13 October 2011

A Delta-Opioid Receptor Gene Polymorphism Moderates the Therapeutic Response to Extended-Release Buprenorphine in Opioid Use Disorder

scientific article published on 13 September 2020

A GABRA2 variant is associated with increased stimulation and 'high' following alcohol administration

scientific article published on 27 October 2013

A double-blind, randomized trial of sertraline for alcohol dependence: moderation by age of onset [corrected] and 5-hydroxytryptamine transporter-linked promoter region genotype

scientific article

A functional neuropeptide Y Leu7Pro polymorphism associated with alcohol dependence in a large population sample from the United States

scientific article

A functional polymorphism of the mu-opioid receptor gene is associated with naltrexone response in alcohol-dependent patients

scientific article

A functional serotonin transporter gene polymorphism and depressive effects associated with interferon-alpha treatment

scientific article published on March 2010

A genome-wide association study of cocaine use disorder accounting for phenotypic heterogeneity and gene–environment interaction

scientific article published on 01 January 2020

A genome-wide gene-by-trauma interaction study of alcohol misuse in two independent cohorts identifies PRKG1 as a risk locus

scientific article published on 07 March 2017

A genomewide linkage scan of cocaine dependence and major depressive episode in two populations

scientific article

A genomewide ordered-subset linkage analysis for alcohol dependence in African-Americans.

scientific article published on 11 October 2010

A large-scale genome-wide association study meta-analysis of cannabis use disorder

scientific article published on 20 October 2020

A meta-analysis of the efficacy of gabapentin for treating alcohol use disorder

scientific article published on 05 June 2019

A multi-site dose ranging study of nalmefene in the treatment of alcohol dependence

scientific article

A prospective cohort study investigating factors associated with depression during medical internship

scientific article

A protocadherin gene cluster regulatory variant is associated with nicotine withdrawal and the urge to smoke.

scientific article published on 12 April 2016

A putative causal relationship between genetically determined female body shape and posttraumatic stress disorder

scientific article published on 27 November 2017

A randomized clinical trial of naltrexone and behavioral therapy for problem drinking men who have sex with men

scientific article published on May 21, 2012

A randomized, multicenter, double-blind, placebo-controlled study of the efficacy and safety of aripiprazole for the treatment of alcohol dependence

scientific article

A regulatory variant of CHRM3 is associated with cannabis-induced hallucinations in European Americans

scientific article published on 18 November 2019

A revised allele frequency estimate and haplotype analysis of the DBH deficiency mutation IVS1+2T → C in African- and European-Americans

article

A serotonin transporter gene polymorphism (5-HTTLPR), drinking-to-cope motivation, and negative life events among college students

scientific article published on November 2008

ACSL6 is associated with the number of cigarettes smoked and its expression is altered by chronic nicotine exposure

scientific article

ADH1A variation predisposes to personality traits and substance dependence

scientific article

ADH4 gene variation is associated with alcohol and drug dependence: results from family controlled and population-structured association studies

scientific article

ADH4 gene variation is associated with alcohol dependence and drug dependence in European Americans: results from HWD tests and case-control association studies

scientific article

ADH7 variation modulates extraversion and conscientiousness in substance-dependent subjects

scientific article

ALDH2 is associated to alcohol dependence and is the major genetic determinant of "daily maximum drinks" in a GWAS study of an isolated rural Chinese sample

scientific journal article

ANKRD7 and CYTL1 are novel risk genes for alcohol drinking behavior

scientific article published on March 1, 2012

AUDIT-C and ICD codes as phenotypes for harmful alcohol use: association with ADH1B polymorphisms in two US populations

scientific article published on 01 August 2018

Acamprosate efficacy in alcohol-dependent patients: summary of results from three pivotal trials

scientific article published on January 2008

Adolescent cannabis use increases risk for cocaine-induced paranoia

scientific article

Adrenocorticotropin and cortisol responses to a naloxone challenge and risk of alcoholism

scientific article published in April 2002

Advances in the pharmacotherapy of alcoholism: challenging misconceptions

scientific article published in February 2006

Advancing Precision Medicine for Alcohol Use Disorder: Replication and Extension of Reward Drinking as a Predictor of Naltrexone Response

scientific article published on 11 September 2019

Adverse childhood events as risk factors for substance dependence: partial mediation by mood and anxiety disorders

scientific article published on 08 August 2009

Agitated depression in substance dependence

scientific article

Alcohol Dependence Genetics: Lessons Learned From Genome-Wide Association Studies (GWAS) and Post-GWAS Analyses

scientific article published on 25 June 2015

Alcohol and nicotine codependence-associated DNA methylation changes in promoter regions of addiction-related genes

scientific article published on 06 February 2017

Alcohol and opioid dependence medications: prescription trends, overall and by physician specialty

scientific article

Alcohol treatment utilization: findings from the National Epidemiologic Survey on Alcohol and Related Conditions

scientific article published on 17 August 2006

Alcohol-responsive genes identified in human iPSC-derived neural cultures

article

Alleles of a functional serotonin transporter promoter polymorphism are associated with major depression in alcoholics

scientific article published in September 2003

Allelic and haplotypic association of GABRA2 with alcohol dependence

scientific article

An Effective Method to Identify Heritable Components from Multivariate Phenotypes

scientific article published on 14 December 2015

An Interpersonal Model of Addiction Relapse

scientific article published on December 2013

An analysis of the effect of mu-opioid receptor gene (OPRM1) promoter region DNA methylation on the response of naltrexone treatment of alcohol dependence

scientific article published on 07 February 2020

Analysis of extreme drinking in patients with alcohol dependence using Pareto regression

scientific article

Analysis of variations in the tryptophan hydroxylase-2 (TPH2) gene in cocaine dependence

scientific article

Ancestry-specific and sex-specific risk alleles identified in a genome-wide gene-by-alcohol dependence interaction study of risky sexual behaviors

scientific article published on 9 October 2017

Apolipoprotein E gene polymorphism, posttraumatic stress disorder, and cognitive function in older U.S. veterans: Results from the National Health and Resilience in Veterans Study

scientific article published on 06 August 2019

Array-based profiling of DNA methylation changes associated with alcohol dependence

scientific article

Association Study of Alcoholism Subtypes with a Functional Promoter Polymorphism in the Serotonin Transporter Protein Gene

article

Association between alcoholism and gamma-amino butyric acid alpha2 receptor subtype in a Russian population

scientific article published in April 2005

Association between polymorphisms in catechol-O-methyltransferase (COMT) and cocaine-induced paranoia in European-American and African-American populations

scientific article published on 08 June 2011

Association between the cortisol response to opioid blockade and the Asn40Asp polymorphism at the mu-opioid receptor locus (OPRM1).

scientific article

Association between two mu-opioid receptor gene (OPRM1) haplotype blocks and drug or alcohol dependence

scientific article

Association of CHRNA4 polymorphisms with smoking behavior in two populations

scientific article published on 28 March 2011

Association of COL25A1 with comorbid antisocial personality disorder and substance dependence

scientific article published on 31 January 2012

Association of OPRM1 Functional Coding Variant With Opioid Use Disorder: A Genome-Wide Association Study

scientific article published on 03 June 2020

Association of a long-chain fatty acid-CoA ligase 4 gene polymorphism with depression and with enhanced niacin-induced dermal erythema

scientific article published in May 2004

Association of an Asn40Asp (A118G) polymorphism in the mu-opioid receptor gene with substance dependence: a meta-analysis

scientific article published on 4 January 2006

Association of gamma-aminobutyric acid A receptor α2 gene (GABRA2) with alcohol use disorder

scientific article

Association of haplotypic variants in DRD2, ANKK1, TTC12 and NCAM1 to alcohol dependence in independent case–control and family samples

Association of markers in the 3' region of the GluR5 kainate receptor subunit gene to alcohol dependence

scientific article published on May 2009

Association of psychiatric and substance use disorder comorbidity with cocaine dependence severity and treatment utilization in cocaine-dependent individuals

scientific article published on 04 September 2008

Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts

scientific article

Association of variants in MANEA with cocaine-related behaviors

scientific article published on March 2009

Association study of DTNBP1 with schizophrenia in a US sample

scientific article

Association study of alcoholism subtypes with a functional promoter polymorphism in the serotonin transporter protein gene

scientific article published in September 2002

Association study of personality factors and the Asn40Asp polymorphism at the mu-opioid receptor gene (OPRM1).

scientific article

Association study of the CNR1 gene exon 3 alternative promoter region polymorphisms and substance dependence

scientific article published on July 2006

Author Correction: Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations

scientific article published on 17 May 2019

Author Correction: Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations

scientific article published on 03 September 2019

Author Correction: Genomewide Study of Epigenetic Biomarkers of Opioid Dependence in European- American Women

scientific article published on 05 December 2019

Autosomal linkage scan for loci predisposing to comorbid dependence on multiple substances

scientific article published on 21 February 2012

Balancing risk and benefit in heavy drinkers treated with topiramate: implications for personalized care

scientific article published on 16 February 2016

Barriers to the use of medications to treat alcoholism.

scientific article

Brain derived neurotrophic factor (BDNF) gene variants and Alzheimer's disease, affective disorders, posttraumatic stress disorder, schizophrenia, and substance dependence

scientific article published on June 2006

Brief motivational enhancement and coping skills interventions for heavy drinking

scientific article published in September 2006

CALCYON gene variation, schizophrenia, and cocaine dependence

scientific article

CHRM2 gene predisposes to alcohol dependence, drug dependence and affective disorders: results from an extended case-control structured association study

scientific article published on 6 July 2005

CNR1 variation modulates risk for drug and alcohol dependence

scientific article

Challenges to medications development in treating alcohol dependence: an international perspective

scientific article

Change in non-abstinent WHO drinking risk levels and alcohol dependence: a 3 year follow-up study in the US general population

scientific article published on 26 April 2017

Characteristics and course of dependence in cocaine-dependent individuals who never used alcohol or marijuana or used cocaine first.

scientific article published on May 2014

Characterization of a likelihood based method and effects of markers informativeness in evaluation of admixture and population group assignment

scientific article

Childhood adversity increases risk for nicotine dependence and interacts with α5 nicotinic acetylcholine receptor genotype specifically in males

scientific article published on 19 October 2011

Circadian Pattern of Deaths Due to Suicide in Intoxicated Alcohol-Dependent Individuals

scientific article published on 23 October 2018

Circadian clock period inversely correlates with illness severity in cells from patients with alcohol use disorders

scientific article published on 29 March 2013

Clinical Validation of Reduced Alcohol Consumption After Treatment for Alcohol Dependence Using the World Health Organization Risk Drinking Levels

scientific article published on 26 December 2016

Cognitive Behavioral Therapy for Insomnia in Alcohol-Dependent Veterans: A Randomized, Controlled Pilot Study

scientific article published on 29 April 2019

Cognitive flexibility is associated with KIBRA variant and modulated by recent tobacco use.

scientific article

Collaborative Phenotype Inference from Comorbid Substance Use Disorders and Genotypes.

scientific article

Commentary on Garbutt et al. (2014): Can we predict who benefits from naltrexone in the treatment of alcohol dependence?

scientific article published on August 2014

Comorbid psychiatric diagnoses and their association with cocaine-induced psychosis in cocaine-dependent subjects

scientific article published in September 2007

Comparing the utility of homogeneous subtypes of cocaine use and related behaviors with DSM-IV cocaine dependence as traits for genetic association analysis

scientific article

Comparison of Alcoholism Subtypes as Moderators of the Response to Sertraline Treatment

scientific article published on September 6, 2011

Comparison of healthcare utilization among patients treated with alcoholism medications

scientific article published on January 1, 2010

Confirmation and generalization of an alcohol-dependence locus on chromosome 10q.

scientific article

Correction: ACSL6 Is Associated with the Number of Cigarettes Smoked and Its Expression Is Altered by Chronic Nicotine Exposure

scientific article published on 14 August 2012

Correlates of Electronic Cigarettes Use Before and During Pregnancy.

scientific article published on May 2017

Correlates of co-occurring ADHD in drug-dependent subjects: prevalence and features of substance dependence and psychiatric disorders

scientific article published on 13 May 2008

Critical evaluation of transcription factor Atf2 as a candidate modulator of alcohol preference in mouse and human populations.

scientific article

Cumulative proportion of responders analysis (CPRA) as a tool to assess treatment outcome in alcohol clinical trials

scientific article published on March 2014

DSM-5 gambling disorder: prevalence and characteristics in a substance use disorder sample

scientific article

Daily relations among affect, urge, targeted naltrexone, and alcohol use in young adults

scientific article

Deep resequencing of 17 glutamate system genes identifies rare variants in DISC1 and GRIN2B affecting risk of opioid dependence

scientific article

Demographic changes and marker properties affect detection of human population differentiation

scientific article

Dense genomewide linkage scan for alcohol dependence in African Americans: significant linkage on chromosome 10.

scientific article published on 18 October 2008

Diagnosis and Pharmacotherapy of Alcohol Use Disorder: A Review

scientific article published on 01 August 2018

Diagnostic reliability of the Semi-structured Assessment for Drug Dependence and Alcoholism (SSADDA).

scientific article published in December 2005

Differentiating Types of Self-Reported Alcohol Abstinence

scientific article published on 01 February 2020

Diplotype trend regression analysis of the ADH gene cluster and the ALDH2 gene: multiple significant associations with alcohol dependence

scientific article

Discovery Of The First Genome-Wide Significant Risk Loci For ADHD

scholarly article published 3 June 2017

Discovery of the first genome-wide significant risk loci for attention deficit/hyperactivity disorder

scientific article published on 26 November 2018

Dissecting the Shared Genetic Architecture of Suicide Attempt, Psychiatric Disorders, and Known Risk Factors

scientific article published in February 2022

Does effect size in naltrexone trials for alcohol dependence differ for single-site vs. multi-center studies?

scientific article published in June 2005

Drinking Risk Level Reductions Associated with Improvements in Physical Health and Quality of Life Among Individuals with Alcohol Use Disorder

scientific article published on 05 November 2018

Drinking goals and attainment in a naltrexone trial of young adult heavy drinkers

scientific article published on 01 September 2018

Drinking to cope: a comparison of questionnaire and electronic diary reports

scientific article

Dual diagnosis: alcoholism and co-morbid psychiatric disorders

scientific article published in January 2003

Dutasteride reduces alcohol's sedative effects in men in a human laboratory setting and reduces drinking in the natural environment

scientific article

Effect of extended-release naltrexone (XR-NTX) on quality of life in alcohol-dependent patients

scientific article

Effect of maternal smoking on fetal catecholamine concentrations at birth

scientific article

Effects of LY466195, a selective kainate receptor antagonist, on ethanol preference and drinking in rats

scientific article published on 21 December 2016

Effects of Recent Alcohol Consumption Level on Neurocognitive Performance in HIV+ Individuals

scientific article published in September 2017

Effects of a diagnosis or family history of alcoholism on the taste intensity and hedonic value of sucrose

scientific article

Effects of aripiprazole on subjective and physiological responses to alcohol

scientific article

Effects of gender and family history of alcohol dependence on a behavioral task of impulsivity in healthy subjects

scientific article

Effects of naltrexone on smoking cessation outcomes and weight gain in nicotine-dependent men and women.

scientific article

Effects of naltrexone treatment for alcohol-related disorders on healthcare costs in an insured population.

scientific article

Effects of nicotine deprivation on urges to drink and smoke in alcoholic smokers

scientific article

Effects of nicotine patch or nasal spray on nicotine and cotinine concentrations in pregnant smokers

scientific article

Effects of ondansetron in early- versus late-onset alcoholics: a prospective, open-label study

scientific article published in July 2003

Effects of opioid receptor gene variation on targeted nalmefene treatment in heavy drinkers

scientific article

Effects of prenatal tobacco exposure on gene expression profiling in umbilical cord tissue.

scientific article published on August 2008

Effects of rapid tryptophan depletion on mood and urge to drink in patients with co-morbid major depression and alcohol dependence

scientific article published on 10 September 2003

Effects of the 2011 duty hour reforms on interns and their patients: a prospective longitudinal cohort study

scientific article

Efficacy and tolerability of long-acting injectable naltrexone for alcohol dependence: a randomized controlled trial

scientific article published in April 2005

Efficacy of Naltrexone and Acamprosate for Alcoholism Treatment: A Meta-Analysis

article

Efficacy of extended-release naltrexone in alcohol-dependent patients who are abstinent before treatment

scientific article published in October 2007

Empirically derived subtypes of opioid use and related behaviors

scientific article

Endorsement of the CONSORT Principles in Reporting Alcohol Clinical Trials in ACER

scientific article published on 24 July 2015

Erratum: Genetic risk prediction and neurobiological understanding of alcoholism

scholarly article published in Translational Psychiatry

Ethical considerations for administering alcohol or alcohol cues to treatment-seeking alcoholics in a research setting: can the benefits to society outweigh the risks to the individual? A commentary in the context of the National Advisory Council on

scientific article published on 10 June 2009

Evaluating the role of a galanin enhancer genotype on a range of metabolic, depressive and addictive phenotypes.

scientific article

Evaluation of Drinking Risk Levels as Outcomes in Alcohol Pharmacotherapy Trials: A Secondary Analysis of 3 Randomized Clinical Trials

scientific article published on 01 April 2019

Evidence of CNIH3 involvement in opioid dependence.

scientific article published on 4 August 2015

Evidence-based treatments for alcohol dependence: new results and new questions

scientific article published on 01 May 2006

Examining FKBP5 mRNA expression in human iPSC-derived neural cells.

scientific article published on 24 November 2016

Examining the effects of alcohol on GABAA receptor mRNA expression and function in neural cultures generated from control and alcohol dependent donor induced pluripotent stem cells

scientific article published on 12 August 2017

Expanding the genetic architecture of nicotine dependence and its shared genetics with multiple traits

scientific article published on 03 November 2020

Exploring the genetic architecture of alcohol dependence in African-Americans via analysis of a genomewide set of common variants

scientific article published on 03 December 2013

Extended-release intramuscular naltrexone: a viewpoint by Henry R Kranzler

scientific article published on 01 January 2006

Eye color: A potential indicator of alcohol dependence risk in European Americans

scientific article published on 29 April 2015

F135GENOMEWIDE SEX-BY-SNP INTERACTION SCAN IDENTIFIES ADGRV1 FOR THE SEX DIFFERENCES OF OPIOID DEPENDENCE IN AFRICAN AMERICAN AND SUPPORTING EVIDENCE IN RELATIONS WITH TREATMENT SIDE EFFECTS IN THE ASIAN POPULATION

article by Bao-Zhu Yang et al published 2019 in European Neuropsychopharmacology

FKBP5 genotype interacts with early life trauma to predict heavy drinking in college students

scientific article published on 19 May 2016

Functional impact of a single-nucleotide polymorphism in the OPRD1 promoter region

scientific article

Functional polymorphisms in the serotonin 1B receptor gene (HTR1B) predict self-reported anger and hostility among young men.

scientific article published in January 2010

Further analyses support the association between light eye color and alcohol dependence

GABRA2 Alcohol Dependence Risk Allele is Associated with Reduced Expression of Chromosome 4p12 GABAA Subunit Genes in Human Neural Cultures

scientific article

GABRA2 alleles moderate the subjective effects of alcohol, which are attenuated by finasteride

scientific article published in June 2005

GABRA2 genotype, impulsivity, and body mass

scientific article published on September 2012

GABRA2 markers moderate the subjective effects of alcohol.

scientific article

GABRG1 and GABRA2 variation associated with alcohol dependence in African Americans

scientific article published on 15 September 2011

GRIK1 genotype and daily expectations of alcohol's positive effects moderate the reduction of heavy drinking by topiramate

scientific article

GRIK1 genotype moderates topiramate's effects on daily drinking level, expectations of alcohol's positive effects and desire to drink

scientific article

GWAS and network analysis of co-occurring nicotine and alcohol dependence identifies significantly associated alleles and network

scientific article published on 28 November 2018

Genetic Association between Dopamine Transporter Protein Alleles and Cocaine-Induced Paranoia

scholarly article by Joel Gelernter et al published April 1995 in Neuropsychopharmacology

Genetic Relationship between Schizophrenia and Nicotine Dependence

scientific article published on 10 May 2016

Genetic Risk Variants Associated With Comorbid Alcohol Dependence and Major Depression.

scientific article published on 25 October 2017

Genetic Vulnerability to Menthol Cigarette Preference in Women.

scientific article published on April 2015

Genetic associations with suicide attempt severity and genetic overlap with major depression

scientific article published on 17 January 2019

Genetic factor common to schizophrenia and HIV infection is associated with risky sexual behavior: antagonistic vs. synergistic pleiotropic SNPs enriched for distinctly different biological functions

scientific article

Genetic risk prediction and neurobiological understanding of alcoholism

scientific article

Genetics of Substance Dependence

article

Genetics of alcohol dependence

article

Genetics of drug dependence

scientific article

Genome-Wide Association Studies of a Broad Spectrum of Antisocial Behavior.

scientific article published on 4 October 2017

Genome-Wide Association Study of Alcohol Dependence Implicates KIAA0040 on Chromosome 1q.

scientific article published on 13 December 2011

Genome-Wide Association Study of Opioid Cessation

scientific article published on 09 January 2020

Genome-Wide Meta-Analyses of FTND and TTFC Phenotypes

scientific article published on 11 July 2019

Genome-wide Association Study Identifies a Regulatory Variant of RGMA Associated With Opioid Dependence in European Americans.

scientific article published on 11 January 2018

Genome-wide Association Study of Cannabis Dependence Severity, Novel Risk Variants, and Shared Genetic Risks

scientific article published on 30 March 2016

Genome-wide Association Study of Maximum Habitual Alcohol Intake in >140,000 U.S. European and African American Veterans Yields Novel Risk Loci

scientific article published on 08 April 2019

Genome-wide association meta-analysis of age at first cannabis use

scientific article published on 19 August 2018

Genome-wide association study across European and African American ancestries identifies a SNP in DNMT3B contributing to nicotine dependence

scientific article published on 3 October 2017

Genome-wide association study identifies glutamate ionotropic receptor GRIA4 as a risk gene for comorbid nicotine dependence and major depression

article

Genome-wide association study identifies new susceptibility loci for posttraumatic stress disorder

scientific journal article

Genome-wide association study in individuals of European and African ancestry and multi-trait analysis of opioid use disorder identifies 19 independent genome-wide significant risk loci

scientific article published in 2022

Genome-wide association study of alcohol consumption and use disorder in 274,424 individuals from multiple populations

scientific article published on 02 April 2019

Genome-wide association study of alcohol dependence implicates KIAA0040 on chromosome 1q

scientific journal article

Genome-wide association study of alcohol dependence:significant findings in African- and European-Americans including novel risk loci

scientific article

Genome-wide association study of body mass index in subjects with alcohol dependence

scientific article published on 12 October 2015

Genome-wide association study of cocaine dependence and related traits: FAM53B identified as a risk gene

scientific article published on 20 August 2013

Genome-wide association study of cognitive flexibility assessed by the Wisconsin Card Sorting Test

scientific article published on 01 July 2018

Genome-wide association study of copy number variations (CNVs) with opioid dependence

scientific article

Genome-wide association study of lifetime cannabis use based on a large meta-analytic sample of 32 330 subjects from the International Cannabis Consortium

scientific article

Genome-wide association study of more than 40,000 bipolar disorder cases provides new insights into the underlying biology

scientific article published in June 2021

Genome-wide association study of nicotine dependence in American populations: identification of novel risk loci in both African-Americans and European-Americans.

scientific article

Genome-wide association study of opioid dependence: multiple associations mapped to calcium and potassium pathways

scientific article published on 19 October 2013

Genome-wide association study of smoking trajectory and meta-analysis of smoking status in 842,000 individuals

scientific article published on 20 October 2020

Genome-wide association study of therapeutic opioid dosing identifies a novel locus upstream of OPRM1.

scientific article published on 24 January 2017

Genome-wide meta-analysis of problematic alcohol use in 435,563 individuals yields insights into biology and relationships with other traits

scientific article published on 25 May 2020

Genome-wide meta-analysis reveals common splice site acceptor variant in CHRNA4 associated with nicotine dependence

scientific article published on 06 October 2015

Genome-wide scan identifies opioid overdose risk locus close to MCOLN1

scientific article published on 30 July 2019

Genomewide Association Study for Maximum Number of Alcoholic Drinks in European Americans and African Americans

scientific article

Genomewide Association Study of Alcohol Dependence Identifies Risk Loci Altering Ethanol-Response Behaviors in Model Organisms

scientific article published on 22 February 2017

Genomewide Gene-by-Sex Interaction Scans Identify ADGRV1 for Sex Differences in Opioid Dependent African Americans

scientific article published on 02 December 2019

Genomewide Linkage Scan for Nicotine Dependence: Identification of a Chromosome 5 Risk Locus

Genomewide Study of Epigenetic Biomarkers of Opioid Dependence in European- American Women

scientific article published on 15 March 2019

Genomewide linkage scan for cocaine dependence and related traits: significant linkages for a cocaine-related trait and cocaine-induced paranoia

scientific article published in July 2005

Genomewide linkage scan for opioid dependence and related traits

scientific article

Genomic influences on self-reported childhood maltreatment

scientific article published on 27 January 2020

Guidelines for biological treatment of substance use and related disorders, part 1: Alcoholism, first revision

scientific article

Guidelines for the Reporting of Treatment Trials for Alcohol Use Disorders

scientific article

Haplotype spanning TTC12 and ANKK1, flanked by the DRD2 and NCAM1 loci, is strongly associated to nicotine dependence in two distinct American populations

scientific article published on 3 November 2006

Haplotypes at the OPRM1 locus are associated with susceptibility to substance dependence in European-Americans

scientific article

Haplotypic variants in DRD2, ANKK1, TTC12, and NCAM1 are associated with comorbid alcohol and drug dependence

scientific article

How Should Addiction-Related Research at the National Institutes of Health be Reorganized?

scientific article

Human clock, PER1 and PER2 polymorphisms: lack of association with cocaine dependence susceptibility and cocaine-induced paranoia

scientific article published in December 2006

Hypermethylation of OPRM1 promoter region in European Americans with alcohol dependence

scientific article

Identification of POMC exonic variants associated with substance dependence and body mass index

scientific article

Identification of methylation quantitative trait loci (mQTLs) influencing promoter DNA methylation of alcohol dependence risk genes

scientific article

Identification of population substructure among Jews using STR markers and dependence on reference populations included

scientific article

Identifying and Reducing Bias in Genome-Wide Association Studies of Alcohol-Related Traits

scientific article published in 2022

Improved methods to identify stable, highly heritable subtypes of opioid use and related behaviors

scientific article

Improvement of physical health and quality of life of alcohol-dependent individuals with topiramate treatment: US multisite randomized controlled trial

scientific article

In Reply

Incentive program decreases no-shows in nontreatment substance abuse research

scientific article published in November 2005

Induced pluripotent stem cell reprogramming-associated methylation at the GABRA2 promoter and chr4p12 GABAA subunit gene expression in the context of alcohol use disorder

scientific article published on 07 October 2020

Inferring phenotypes from substance use via collaborative matrix completion

scholarly article by Jin Lu published in November 2018

Insomnia in Alcohol Dependence: Predictors of Symptoms in a Sample of Veterans Referred from Primary Care

scientific article published in March 2013

Insomnia in alcohol dependence: predictors of symptoms in a sample of veterans referred from primary care

scientific article

Insomnia in alcohol dependent subjects is associated with greater psychosocial problem severity

scientific article published on 20 June 2015

Integrating GWASs and human protein interaction networks identifies a gene subnetwork underlying alcohol dependence

scientific article

Integrating human brain proteomic data with genome-wide association study findings identifies novel brain proteins in substance use traits

scientific article published in 2022

Inter-observer reliability of DSM-5 substance use disorders

scientific article published on 27 May 2015

Inter-rater reliability and concurrent validity of DSM-IV opioid dependence in a Hmong isolate using the Thai version of the Semi-Structured Assessment for Drug Dependence and Alcoholism (SSADDA).

scientific article

Interaction between two independent CNR1 variants increases risk for cocaine dependence in European Americans: a replication study in family-based sample and population-based sample

scientific article

Interaction of FKBP5 with childhood adversity on risk for post-traumatic stress disorder

scientific article

Interactive Effects of the Serotonin Transporter 5-HTTLPR Polymorphism and Stressful Life Events on College Student Drinking and Drug Use

scientific article published on 22 August 2006

Interactive effect of stressful life events and the serotonin transporter 5-HTTLPR genotype on posttraumatic stress disorder diagnosis in 2 independent populations

scientific article

International meta-analysis of PTSD genome-wide association studies identifies sex- and ancestry-specific genetic risk loci

scientific article published on 08 October 2019

Interpopulation linkage disequilibrium patterns of GABRA2 and GABRG1 genes at the GABA cluster locus on human chromosome 4

scientific article

Intronic variants in the dopa decarboxylase (DDC) gene are associated with smoking behavior in European-Americans and African-Americans

scientific article

Largest GWAS of PTSD (N=20 070) yields genetic overlap with schizophrenia and sex differences in heritability.

scientific article published on 25 April 2017

Largest genome-wide association study for PTSD identifies genetic risk loci in European and African ancestries and implicates novel biological pathways

article published in 2018

Letter to the Editor

Leveraging genome-wide data to investigate differences between opioid use vs. opioid dependence in 41,176 individuals from the Psychiatric Genomics Consortium

scientific article published on 26 February 2020

Linkage analysis followed by association show NRG1 associated with cannabis dependence in African Americans

scientific article published on 19 April 2012

Long-term use of hydrocodone vs. oxycodone in primary care

scientific article published on 02 November 2019

Longitudinal Drinking Patterns and Their Clinical Correlates in Million Veteran Program Participants

scientific article published on 03 February 2019

Longitudinal findings from a randomized clinical trial of naltrexone for young adult heavy drinkers

scientific article published on 14 December 2015

M(3): an improved SNP calling algorithm for Illumina BeadArray data

scientific article

Maintenance of World Health Organization Risk Drinking Level Reductions and Posttreatment Functioning Following a Large Alcohol Use Disorder Clinical Trial.

scientific article published on 5 April 2019

Major depression and PTSD in pregnant smokers enrolled in nicotine gum treatment trial

scientific article published in January 2013

Markers in the 5'-region of GABRG1 associate to alcohol dependence and are in linkage disequilibrium with markers in the adjacent GABRA2 gene

scientific article

Measurement and prediction of medication compliance in problem drinkers

scientific article published in August 2003

Measurement of admixture proportions and description of admixture structure in different U.S. populations

scientific article

Mecamylamine modifies the pharmacokinetics and reinforcing effects of alcohol

scientific article

Medications to treat heavy drinking: are we there yet?

scientific article published in February 2006

Meta-Analysis of the Association of Alcohol-Related Social Media Use with Alcohol Consumption and Alcohol-Related Problems in Adolescents and Young Adults

scientific article published on 22 May 2018

Meta-analysis of the association of a functional serotonin transporter promoter polymorphism with alcohol dependence

scientific article published in February 2005

Methamphetamine and paranoia: the methamphetamine experience questionnaire

scientific article

Methods to analyze treatment effects in the presence of missing data for a continuous heavy drinking outcome measure when participants drop out from treatment in alcohol clinical trials

scientific article

Missing Data in Alcohol Clinical Trials with Binary Outcomes

scientific article

Molecular Correlates of Topiramate and GRIK1 rs2832407 Genotype in Pluripotent Stem Cell-Derived Neural Cultures

scientific article published on 23 June 2020

Multi-trait genome-wide association study of opioid addiction: OPRM1 and beyond

scientific article published in 2022

Multi-view singular value decomposition for disease subtyping and genetic associations

scientific article

Multiple ADH genes modulate risk for drug dependence in both African- and European-Americans

scientific article

Multiple OPR genes influence personality traits in substance dependent and healthy subjects in two American populations

scientific article

Multivariate analysis of 1.5 million people identifies genetic associations with traits related to self-regulation and addiction

scientific article published on 26 August 2021

Multiview comodeling to improve subtyping and genetic association of complex diseases

scientific article published on March 2014

Mutation screen of the glutamate decarboxylase-67 gene and haplotype association to unipolar depression

scientific article published in January 2004

Mutation screen of theGAD2 gene and association study of alcoholism in three populations

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NOTCH4 gene haplotype is associated with schizophrenia in African Americans

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Naltrexone and Brief Counseling to Reduce Heavy Drinking:Results of a Small Clinical Trial

Naltrexone depot for treatment of alcohol dependence: a multicenter, randomized, placebo-controlled clinical trial

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Nefazodone treatment of comorbid alcohol dependence and major depression

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New Initiatives for Alcoholism: Clinical and Experimental Research

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New and Revised Policies for Alcoholism: Clinical and Experimental Research (ACER)

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Nf1 regulates alcohol dependence-associated excessive drinking and gamma-aminobutyric acid release in the central amygdala in mice and is associated with alcohol dependence in humans

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Nicotine gum for pregnant smokers: a randomized controlled trial

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No association between ADCYAP1R1 and post-traumatic stress disorder in two independent samples

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Nogo 3'-untranslated region CAA insertion: failure to replicate association with schizophrenia and demonstration of marked population difference in frequency of the insertion

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Opioid Misuse as a Predictor of Alcohol Treatment Outcomes in the COMBINE Study: Mediation by Medication Adherence

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Opioid Use and Rate of Nicotine Metabolism among Pregnant Smokers

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Opioid receptor gene (OPRM1, OPRK1, and OPRD1) variants and response to naltrexone treatment for alcohol dependence: results from the VA Cooperative Study

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Opioid-, cannabis- and alcohol-dependent women show more rapid progression to substance abuse treatment

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Ordered subset linkage analysis based on admixture proportion identifies new linkage evidence for alcohol dependence in African-Americans

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Oxytocin receptor gene polymorphisms, attachment, and PTSD: Results from the National Health and Resilience in Veterans Study

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PM296. SORCS2 regulates alcohol withdrawal severity and excitatory synaptic transmission.

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Patient Predictors of Irregular Discharge from Inpatient Substance Abuse Treatment

Patterns and Correlates of Prescription Opioid Receipt Among US Veterans: A National, 18-Year Observational Cohort Study

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Persistence with oral naltrexone for alcohol treatment: implications for health-care utilization.

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Personality traits of agreeableness and extraversion are associated with ADH4 variation

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Personalized Treatment of Alcohol Dependence

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Pharmacogenetics of alcohol and alcohol dependence treatment

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Pharmacogenetics of alcohol use disorder treatments: an update

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Pharmacotherapy of alcohol use disorders: seventy-five years of progress

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Phenome-Wide Association Study for Alcohol and Nicotine Risk Alleles in 26394 Women

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Physicians’ opinions about medications to treat alcoholism

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Pilot study of iPS-derived neural cells to examine biologic effects of alcohol on human neurons in vitro

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Placebo-controlled trial of zonisamide for the treatment of alcohol dependence

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Polygenic Scores for Major Depressive Disorder and Risk of Alcohol Dependence

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Polygenic risk for alcohol dependence associates with alcohol consumption, cognitive function and social deprivation in a population-based cohort

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Polymorphism of the 5-HT1B receptor gene (HTR1B): strong within-locus linkage disequilibrium without association to antisocial substance dependence

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Population admixture modulates risk for alcohol dependence

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Population-specific effects of the Asn40Asp polymorphism at the mu-opioid receptor gene (OPRM1) on HPA-axis activation

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Post-GWAS analysis of six substance use traits improves the identification and functional interpretation of genetic risk loci

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Posttreatment effects of topiramate treatment for heavy drinking.

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Post‐Treatment Outcomes in a Double‐Blind, Randomized Trial of Sertraline for Alcohol Dependence

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Practical population group assignment with selected informative markers: Characteristics and properties of Bayesian clustering via STRUCTURE

Precision medicine and pharmacogenetics: what does oncology have that addiction medicine does not?

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Predictors of Treatment Referral after AUDIT-C Screening for Heavy Drinking

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Prevalence of DSM-IV and DSM-5 alcohol, cocaine, opioid, and cannabis use disorders in a largely substance dependent sample

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Prevention, screening, and treatment for heavy drinking and alcohol use disorder

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Pro-opiomelanocortin gene variation related to alcohol or drug dependence: evidence and replications across family- and population-based studies

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Profiling of childhood adversity-associated DNA methylation changes in alcoholic patients and healthy controls

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Psychometric Properties of the Short Index of Problems as a Measure of Recent Alcohol‐Related Problems

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Quantitative real-time PCR for gene dosage determinations in microdeletion genotypes

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Randomized Trial of Nicotine Inhaler for Pregnant Smokers

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Rare nonsynonymous variants in alpha-4 nicotinic acetylcholine receptor gene protect against nicotine dependence

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Rate of progression from first use to dependence on cocaine or opioids: a cross-substance examination of associated demographic, psychiatric, and childhood risk factors

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Rating the severity and character of transient cocaine-induced delusions and hallucinations with a new instrument, the Scale for Assessment of Positive Symptoms for Cocaine-Induced Psychosis (SAPS-CIP).

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Recessive genetic mode of an ADH4 variant in substance dependence in African-Americans: A model of utility of the HWD test

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Recommendations for the Design and Analysis of Treatment Trials for Alcohol Use Disorders

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Reduction in Nonabstinent WHO Drinking Risk Levels and Change in Risk for Liver Disease and Positive AUDIT-C Scores: Prospective 3-Year Follow-Up Results in the U.S. General Population

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Reduction in World Health Organization Risk Drinking Levels and Cardiovascular Disease

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Reduction in non-abstinent WHO drinking risk levels and depression/anxiety disorders: 3-year follow-up results in the US general population

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Reduction in non-abstinent World Health Organization (WHO) drinking risk levels and drug use disorders: 3-year follow-up results in the US general population

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Reduction of alcohol drinking in young adults by naltrexone: a double-blind, placebo-controlled, randomized clinical trial of efficacy and safety

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Reductions in Alcohol Craving Following Naltrexone Treatment for Heavy Drinking

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Refining multivariate disease phenotypes for high chip heritability

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Reliability of DSM-IV diagnostic criteria using the semi-structured assessment for drug dependence and alcoholism (SSADDA).

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Response to Dr. Kopke's comments on haplotypes at the OPRM1 locus

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Risk Locus Identification Ties Alcohol Withdrawal Symptoms to SORCS2

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Risk factors for cocaine-induced paranoia in cocaine-dependent sibling pairs

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Risks of alcohol use disorders related to drinking patterns in the U.S. general population

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S100A10 identified in a genome-wide gene × cannabis dependence interaction analysis of risky sexual behaviours

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Salivary microRNAs identified by small RNA sequencing and machine learning as potential biomarkers of alcohol dependence

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Salty and sour taste characteristics and risk of alcoholism

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Screening for health behaviors in ambulatory clinical settings: does smoking status predict hazardous drinking?

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Self-efficacy mediates the effects of topiramate and GRIK1 genotype on drinking

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Sequence variation and linkage disequilibrium in the GABA transporter-1 gene (SLC6A1) in five populations: implications for pharmacogenetic research

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Serotonin transporter 5-HTTLPR genotype moderates the effects of childhood adversity on posttraumatic stress disorder risk: a replication study

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Serotonin transporter gene polymorphism (5-HTTLPR) and anxiety reactivity in daily life: a daily process approach to gene-environment interaction

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Sertraline treatment of co-occurring alcohol dependence and major depression

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Sex-specific linkage scans in opioid dependence

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Shared genetic risk between eating disorder- and substance-use-related phenotypes: Evidence from genome-wide association studies

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Should the reorganization of addiction-related research across all the National Institutes of Health be structural?--The devil is truly in the details

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Smoking and Cellular Telephone Use Among Pregnant Women Seeking Prenatal Care: Opportunities for Intervention

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Sources of unreliability in the diagnosis of substance dependence.

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Speaker 4: Joel Gelernter, USA.

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Stability of Drinking Reductions and Long-term Functioning Among Patients with Alcohol Use Disorder

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Stage of Change as a Predictor of Abstinence Among Alcohol-Dependent Subjects in Pharmacotherapy Trials

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Study design and implementation of the PRecision Medicine In MEntal health Care (PRIME Care) Trial

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Subgroup Identification in Personalized Treatment of Alcohol Dependence

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Subjective effects and changes in steroid hormone concentrations in humans following acute consumption of alcohol

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Substance dependence low-density whole genome association study in two distinct American populations

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Subtypes of major depression in substance dependence.

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Survey of Addiction Specialists' Use of Medications to Treat Alcohol Use Disorder

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Systematic review and meta-analysis of the moderating effect of rs1799971 in OPRM1, the mu-opioid receptor gene, on response to naltrexone treatment of alcohol use disorder

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Targeted naltrexone for early problem drinkers

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Targeted naltrexone for problem drinkers

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Targeted naltrexone treatment moderates the relations between mood and drinking behavior among problem drinkers

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Targeted versus daily naltrexone: secondary analysis of effects on average daily drinking

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Temporal Stability of Heavy Drinking Days and Drinking Reductions Among Heavy Drinkers in the COMBINE Study

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The 5‐HTTLPR polymorphism moderates the effect of stressful life events on drinking behavior in college students of African descent

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The Alcohol Clinical Trials Initiative (ACTIVE): Purpose and Goals for Assessing Important and Salient Issues for Medications Development in Alcohol Use Disorders

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The Identification and Treatment of Alcohol Abuse and Dependency

The Interplay Between Risky Sexual Behaviors and Alcohol Dependence: Genome-Wide Association and Neuroimaging Support for LHPP as a Risk Gene

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The World Federation of Societies of Biological Psychiatry (WFSBP) guidelines for the biological treatment of substance use and related disorders. Part 2: Opioid dependence

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The contribution of genetics to addiction therapy approaches

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The effect of cigarette smoking on fetal heart rate characteristics

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The effects of a MAP2K5 microRNA target site SNP on risk for anxiety and depressive disorders

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The effects of naltrexone on alcohol consumption and affect reactivity to daily interpersonal events among heavy drinkers

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The joint effects of ADH1B variants and childhood adversity on alcohol related phenotypes in African-American and European-American women and men

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The pharmacogenetics of alcohol use disorder

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The status of serotonin-selective pharmacotherapy in the treatment of alcohol dependence

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The validity of cocaine dependence subtypes

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The α-endomannosidase gene (MANEA) is associated with panic disorder and social anxiety disorder

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Topiramate for smoking cessation: a randomized, placebo-controlled pilot study

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Topiramate for treating alcohol dependence: a randomized controlled trial

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Topiramate treatment for heavy drinkers: moderation by a GRIK1 polymorphism

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Topiramate versus naltrexone for alcohol use disorder: study protocol for a genotype-stratified, double-blind randomised controlled trial (TOP study)

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Topiramate's reduction of body mass index in heavy drinkers: lack of moderation by a GRIK1 polymorphism

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Trans-ancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

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Transancestral GWAS of alcohol dependence reveals common genetic underpinnings with psychiatric disorders

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Transdermal nicotine for smoking cessation in postmenopausal women

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Transient Cocaine-Associated Behavioral Symptoms Rated with a New Instrument, the Scale for Assessment of Positive Symptoms for Cocaine-Induced Psychosis (SAPS-CIP)

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Transient cocaine-associated behavioral symptoms rated with a new instrument, the scale for assessment of positive symptoms for cocaine-induced psychosis (SAPS-CIP).

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Translating the semi-structured assessment for drug dependence and alcoholism in the Western Pacific: rationale, study design and reliability of alcohol dependence

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Translational studies support a role for serotonin 2B receptor (HTR2B) gene in aggression-related cannabis response

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Trauma exposure interacts with the genetic risk of bipolar disorder in alcohol misuse of US soldiers.

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Treatment of co-occurring alcohol and other drug use disorders

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Tryptophan hydroxylase 2 gene and alcohol use among college students

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Ttn as a likely causal gene for QTL of alcohol preference on mouse chromosome 2

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Typologies of drug dependence: comparative validity of a multivariate and four univariate models

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Understanding US addiction physicians' low rate of naltrexone prescription

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Urgency traits moderate daily relations between affect and drinking to intoxication among young adults

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Using DNA methylation to validate an electronic medical record phenotype for smoking

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Using daily interactive voice response technology to measure drinking and related behaviors in a pharmacotherapy study

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Validating Harmful Alcohol Use as a Phenotype for Genetic Discovery Using Phosphatidylethanol and a Polymorphism in ADH1B.

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Validating a non-invasive, ALT-based non-alcoholic fatty liver phenotype in the million veteran program

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Validity of the Distinction Between “Substance-Induced” and “Independent” Depressio and Anxiety Disorders

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Variant detection at the ? opioid receptor (OPRD1) locus and population genetics of a novel variant affecting protein sequence

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Variation at APOE and STH loci and Alzheimer's disease

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Variation in AKR1C3, which encodes the neuroactive steroid synthetic enzyme 3α-HSD type 2 (17β-HSD type 5), moderates the subjective effects of alcohol

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Variation in GABRA2 predicts drinking behavior in project MATCH subjects

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Variation in Mu-Opioid Receptor Gene (OPRM1) as a Moderator of Naltrexone Treatment to Reduce Heavy Drinking in a High Functioning Cohort

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Variation in NGFB is associated with primary affective disorders in women

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Variation in OPRM1 and risk of suicidal behavior in drug-dependent individuals

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Variation in OPRM1 moderates the effect of desire to drink on subsequent drinking and its attenuation by naltrexone treatment

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Variation in genes encoding the neuroactive steroid synthetic enzymes 5α-reductase type 1 and 3α-reductase type 2 is associated with alcohol dependence

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Variation in nicotinic acetylcholine receptor genes is associated with multiple substance dependence phenotypes

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Variation in regulator of G-protein signaling 17 gene (RGS17) is associated with multiple substance dependence diagnoses

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Variation in the gene encoding the serotonin transporter is associated with a measure of sociopathy in alcoholics

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Variation in the nicotinic acetylcholine receptor gene cluster CHRNA5-CHRNA3-CHRNB4 and its interaction with recent tobacco use influence cognitive flexibility

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What happens when people discontinue taking medications? Lessons from COMBINE.

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What is addiction?

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Which alcohol use disorder criteria contribute to the association of ADH1B with alcohol dependence?

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World Federation of Societies of Biological Psychiatry (WFSBP) Guidelines for Biological Treatment of Substance Use and Related Disorders, Part 1: Alcoholism

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World Health Organization risk drinking level reductions are associated with improved functioning and are sustained among patients with mild, moderate and severe alcohol dependence in clinical trials in the United States and United Kingdom

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