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List of works by Claudia Manzoni

A recessive mutation in the APP gene with dominant-negative effect on amyloidogenesis.

scientific article published on March 2009

Acetylcholinesterase triggers the aggregation of PrP 106-126

scientific article published on 24 May 2006

Analysis of macroautophagy related proteins in G2019S LRRK2 Parkinson's disease brains with Lewy body pathology

scientific article published on 25 July 2018

C9orf72, AAO and ancestry help discriminating behavioural from language variants in FTLD cohorts

scientific article published on 17 September 2020

Cellular processes associated with LRRK2 function and dysfunction

scientific article published on 09 May 2015

Computational analysis of the LRRK2 interactome

scientific article

Divergent α-synuclein solubility and aggregation properties in G2019S LRRK2 Parkinson's disease brains with Lewy Body pathology compared to idiopathic cases ⬇️

scientific article published on 05 June 2013

GTP binding and intramolecular regulation by the ROC domain of Death Associated Protein Kinase 1.

scientific article

Genetic and phenotypic characterization of complex hereditary spastic paraplegia

scientific article published on 23 May 2016

Genetic variation across RNA metabolism and cell death gene networks is implicated in the semantic variant of primary progressive aphasia

scientific article published on 26 July 2019

Genetics and molecular mechanisms of frontotemporal lobar degeneration: an update and future avenues

scientific article published on 14 February 2019

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Inhibition of LRRK2 kinase activity stimulates macroautophagy

scientific journal article

Integrating protein networks and machine learning for disease stratification in the Hereditary Spastic Paraplegias

scientific article published on 28 April 2021

LRRK2 and autophagy: a common pathway for disease.

scientific article published on October 2012

LRRK2: a problem lurking in vesicle trafficking?

scientific article published on July 2011

MIR-NATs repress MAPT translation and aid proteostasis in neurodegeneration

scientific article published on 19 May 2021

Measuring Lactase Enzymatic Activity in the Teaching Lab

scientific article published on 06 August 2018

Neurotoxic and gliotrophic activity of a synthetic peptide homologous to Gerstmann-Sträussler-Scheinker disease amyloid protein.

scientific article published in February 2007

Overcoming synthetic Abeta peptide aging: a new approach to an age-old problem.

scientific article published in January 2009

PINOT: an intuitive resource for integrating protein-protein interactions

scientific article published on 11 June 2020

Pathogenic Parkinson's disease mutations across the functional domains of LRRK2 alter the autophagic/lysosomal response to starvation

scientific journal article

Preclinical modeling of chronic inhibition of the Parkinson's disease associated kinase LRRK2 reveals altered function of the endolysosomal system in vivo

scientific article published on 19 March 2021

Synthetic amyloid-beta oligomers impair long-term memory independently of cellular prion protein

scientific article

Tau Mutations Serve as a Novel Risk Factor for Cancer

scientific article published on 24 May 2018

Tetracycline prevents Aβ oligomer toxicity through an atypical supramolecular interaction.

scientific article

The LRRK2 signalling system

scientific article published on 8 January 2018

The LRRK2-macroautophagy axis and its relevance to Parkinson's disease

scientific article published on February 2017

The SIRT1 activator resveratrol protects SK-N-BE cells from oxidative stress and against toxicity caused by alpha-synuclein or amyloid-beta (1-42) peptide.

scientific article

The molecular assembly of amyloid aβ controls its neurotoxicity and binding to cellular proteins

scientific article (publication date: 2011)

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