List of works - Xiangning Chen

A Twin Association Study of Nicotine Dependence with Markers in the CHRNA3 and CHRNA5 Genes ⬇️

scientific article published on July 12, 2011

A bias-reducing pathway enrichment analysis of genome-wide association data confirmed association of the MHC region with schizophrenia

scientific article

A multi-dimensional evidence-based candidate gene prioritization approach for complex diseases-schizophrenia as a case

scientific article published on 14 July 2009

A rare functional noncoding variant at the GWAS-implicated MIR137/MIR2682 locus might confer risk to schizophrenia and bipolar disorder

scientific article

ACSL6 is associated with the number of cigarettes smoked and its expression is altered by chronic nicotine exposure

scientific article

An association between Epac-1 gene variants and anxiety and depression in two independent samples

scientific article

Apoptotic engulfment pathway and schizophrenia

scientific article

Association and expression study of synapsin III and schizophrenia

scientific article published on 19 September 2009

Association between the 5q31.1 gene neurogenin1 and schizophrenia

scientific article

Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts

scientific article

Association of the phosphatase and tensin homolog gene (PTEN) with smoking initiation and nicotine dependence

scientific article

Association study between GABA receptor genes and anxiety spectrum disorders

scientific article published on January 2009

Association study of 167 candidate genes for schizophrenia selected by a multi-domain evidence-based prioritization algorithm and neurodevelopmental hypothesis

scientific article

Association study of CREB1 with Major Depressive Disorder and related phenotypes

scientific article

Association study of the Epac gene and tobacco smoking and nicotine dependence

scientific article

Associations of glutamate decarboxylase genes with initial sensitivity and age-at-onset of alcohol dependence in the Irish Affected Sib Pair Study of Alcohol Dependence

scientific article

Cannabinoid receptor 1 gene association with nicotine dependence

scientific article published on July 2008

Catechol-O-methyltransferase contributes to genetic susceptibility shared among anxiety spectrum phenotypes

scientific article published on 23 April 2008

Convergent roles of de novo mutations and common variants in schizophrenia in tissue-specific and spatiotemporal co-expression network.

scientific article

Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking

scientific article

Evaluation of a susceptibility gene for schizophrenia: genotype based meta-analysis of RGS4 polymorphisms from thirteen independent samples

scientific article

FBXL21 association with schizophrenia in Irish family and case-control samples

scientific article

Follow-up association study of novel neuroticism gene MAMDC1.

scientific article

Genetic Relationship between Schizophrenia and Nicotine Dependence

scientific article published on 10 May 2016

Genetic association between RGS1 and internalizing disorders

scientific article published on April 2013

Genetic risks to nicotine dependence predict negative mood and affect in current non-smokers

scientific article published on 31 March 2015

Genetic variation in the serotonin 2A receptor and suicidal ideation in a sample of 270 Irish high-density schizophrenia families

scientific article

Genome-Wide Meta-Analysis of Cotinine Levels in Cigarette Smokers Identifies Locus at 4q13.2.

scientific article published on February 2016

Haplotypes spanning SPEC2, PDZ-GEF2 and ACSL6 genes are associated with schizophrenia

scientific article

Incidence of Cancer in Patients With Schizophrenia and Their First-Degree Relatives: A Population-Based Study in Sweden ⬇️

scientific article published on April 20, 2012

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

scientific article

Interaction between interleukin 3 and dystrobrevin-binding protein 1 in schizophrenia

scientific article

Is the histidine triad nucleotide-binding protein 1 (HINT1) gene a candidate for schizophrenia?

scientific article published on 16 September 2008

Lack of association between the amiloride-sensitive cation channel 2 (ACCN2) gene and anxiety spectrum disorders

scientific article

MEGF10 association with schizophrenia

scientific article

Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.

scientific article

Nicotine reward and affective nicotine withdrawal signs are attenuated in calcium/calmodulin-dependent protein kinase IV knockout mice ⬇️

scientific article

On schizophrenia as a “disease of humanity” ⬇️

scientific article published on November 20, 2012

Prioritization and association analysis of murine-derived candidate genes in anxiety-spectrum disorders

scientific article

RNA-Seq analysis implicates dysregulation of the immune system in schizophrenia

scientific article

Recent advances in the genetic epidemiology and molecular genetics of substance use disorders ⬇️

scientific article published on January 26, 2012

Regulator of G-protein signaling 4 (RGS4) gene is associated with schizophrenia in Irish high density families

scientific article

SIRT1 activates MAO-A in the brain to mediate anxiety and exploratory drive

scientific article

Schizophrenia gene networks and pathways and their applications for novel candidate gene selection

scientific article

Support for involvement of glutamate decarboxylase 1 and neuropeptide Y in anxiety susceptibility

scientific article published on 10 February 2012

The AVPR1A gene and substance use disorders: association, replication, and functional evidence

scientific article

The Neuropeptide Galanin and Variants in the GalR1 Gene are Associated with Nicotine Dependence ⬇️

scientific article published on July 27, 2011

The mu-opioid receptor gene and smoking initiation and nicotine dependence

scientific article

Total Exposure Study Analysis consortium: a cross-sectional study of tobacco exposures

scientific article

Transcriptome sequencing and genome-wide association analyses reveal lysosomal function and actin cytoskeleton remodeling in schizophrenia and bipolar disorder

scientific article

Two non-synonymous markers in PTPN21, identified by genome-wide association study data-mining and replication, are associated with schizophrenia

scientific article

Variants in nicotinic acetylcholine receptors alpha5 and alpha3 increase risks to nicotine dependence

scientific article

Variants in the 15q25 gene cluster are associated with risk for schizophrenia and bipolar disorder ⬇️

scientific article published on February 1, 2013

List of works by Xiangning Chen

A Twin Association Study of Nicotine Dependence with Markers in the CHRNA3 and CHRNA5 Genes ⬇️

A bias-reducing pathway enrichment analysis of genome-wide association data confirmed association of the MHC region with schizophrenia

A multi-dimensional evidence-based candidate gene prioritization approach for complex diseases-schizophrenia as a case

A rare functional noncoding variant at the GWAS-implicated MIR137/MIR2682 locus might confer risk to schizophrenia and bipolar disorder

ACSL6 is associated with the number of cigarettes smoked and its expression is altered by chronic nicotine exposure

An association between Epac-1 gene variants and anxiety and depression in two independent samples

Apoptotic engulfment pathway and schizophrenia

Association and expression study of synapsin III and schizophrenia

Association between the 5q31.1 gene neurogenin1 and schizophrenia

Association of the OPRM1 Variant rs1799971 (A118G) with Non-Specific Liability to Substance Dependence in a Collaborative de novo Meta-Analysis of European-Ancestry Cohorts

Association of the phosphatase and tensin homolog gene (PTEN) with smoking initiation and nicotine dependence

Association study between GABA receptor genes and anxiety spectrum disorders

Association study of 167 candidate genes for schizophrenia selected by a multi-domain evidence-based prioritization algorithm and neurodevelopmental hypothesis

Association study of CREB1 with Major Depressive Disorder and related phenotypes

Association study of the Epac gene and tobacco smoking and nicotine dependence

Associations of glutamate decarboxylase genes with initial sensitivity and age-at-onset of alcohol dependence in the Irish Affected Sib Pair Study of Alcohol Dependence

Cannabinoid receptor 1 gene association with nicotine dependence

Catechol-O-methyltransferase contributes to genetic susceptibility shared among anxiety spectrum phenotypes

Convergent roles of de novo mutations and common variants in schizophrenia in tissue-specific and spatiotemporal co-expression network.

Distinct loci in the CHRNA5/CHRNA3/CHRNB4 gene cluster are associated with onset of regular smoking

Evaluation of a susceptibility gene for schizophrenia: genotype based meta-analysis of RGS4 polymorphisms from thirteen independent samples

FBXL21 association with schizophrenia in Irish family and case-control samples

Follow-up association study of novel neuroticism gene MAMDC1.

Genetic Relationship between Schizophrenia and Nicotine Dependence

Genetic association between RGS1 and internalizing disorders

Genetic risks to nicotine dependence predict negative mood and affect in current non-smokers

Genetic variation in the serotonin 2A receptor and suicidal ideation in a sample of 270 Irish high-density schizophrenia families

Genome-Wide Meta-Analysis of Cotinine Levels in Cigarette Smokers Identifies Locus at 4q13.2.

Haplotypes spanning SPEC2, PDZ-GEF2 and ACSL6 genes are associated with schizophrenia

Incidence of Cancer in Patients With Schizophrenia and Their First-Degree Relatives: A Population-Based Study in Sweden ⬇️

Increased genetic vulnerability to smoking at CHRNA5 in early-onset smokers

Interaction between interleukin 3 and dystrobrevin-binding protein 1 in schizophrenia

Is the histidine triad nucleotide-binding protein 1 (HINT1) gene a candidate for schizophrenia?

Lack of association between the amiloride-sensitive cation channel 2 (ACCN2) gene and anxiety spectrum disorders

MEGF10 association with schizophrenia

Multiple independent loci at chromosome 15q25.1 affect smoking quantity: a meta-analysis and comparison with lung cancer and COPD.

Nicotine reward and affective nicotine withdrawal signs are attenuated in calcium/calmodulin-dependent protein kinase IV knockout mice ⬇️

On schizophrenia as a “disease of humanity” ⬇️

Prioritization and association analysis of murine-derived candidate genes in anxiety-spectrum disorders

RNA-Seq analysis implicates dysregulation of the immune system in schizophrenia

Recent advances in the genetic epidemiology and molecular genetics of substance use disorders ⬇️

Regulator of G-protein signaling 4 (RGS4) gene is associated with schizophrenia in Irish high density families

SIRT1 activates MAO-A in the brain to mediate anxiety and exploratory drive

Schizophrenia gene networks and pathways and their applications for novel candidate gene selection

Support for involvement of glutamate decarboxylase 1 and neuropeptide Y in anxiety susceptibility

The AVPR1A gene and substance use disorders: association, replication, and functional evidence

The Neuropeptide Galanin and Variants in the GalR1 Gene are Associated with Nicotine Dependence ⬇️

The mu-opioid receptor gene and smoking initiation and nicotine dependence

Total Exposure Study Analysis consortium: a cross-sectional study of tobacco exposures

Transcriptome sequencing and genome-wide association analyses reveal lysosomal function and actin cytoskeleton remodeling in schizophrenia and bipolar disorder

Two non-synonymous markers in PTPN21, identified by genome-wide association study data-mining and replication, are associated with schizophrenia

Variants in nicotinic acetylcholine receptors alpha5 and alpha3 increase risks to nicotine dependence

Variants in the 15q25 gene cluster are associated with risk for schizophrenia and bipolar disorder ⬇️