List of works - Ilia V. Baskakov

A new mechanism for transmissible prion diseases

scientific article

Amyloid features and neuronal toxicity of mature prion fibrils are highly sensitive to high pressure

scientific article

Amyloid fibrils of mammalian prion protein induce axonal degeneration in NTERA2-derived terminally differentiated neurons

scientific article published on May 2007

Analysis of Covalent Modifications of Amyloidogenic Proteins Using Two-Dimensional Electrophoresis: Prion Protein and Its Sialylation

scientific article published on 01 January 2018

Annealing prion protein amyloid fibrils at high temperature results in extension of a proteinase K-resistant core

scientific article published on 28 November 2005

Assessment of Strain-Specific PrPSc Elongation Rates Revealed a Transformation of PrPSc Properties during Protein Misfolding Cyclic Amplification ⬇️

scientific article published on July 17, 2012

Atomic force fluorescence microscopy in the characterization of amyloid fibril assembly and oligomeric intermediates

scientific article published on January 2012

Atypical and classical forms of the disease-associated state of the prion protein exhibit distinct neuronal tropism, deposition patterns, and lesion profiles

scientific article published on 05 September 2013

Changes in prion replication environment cause prion strain mutation

scientific article published on 31 May 2013

Chemoenzymatic synthesis of HIV-1 V3 glycopeptides carrying two N-glycans and effects of glycosylation on the peptide domain

scientific article

Conformational stability of PrP amyloid fibrils controls their smallest possible fragment size

scientific article

Conformational switching within individual amyloid fibrils.

scientific article

Converting the prion protein: what makes the protein infectious.

scientific article published on 25 July 2006

Copper(II) inhibits in vitro conversion of prion protein into amyloid fibrils.

scientific article

Correction to: preserving prion strain identity upon replication of prions in vitro using recombinant prion protein

scholarly article published in Acta neuropathologica communications

Cross-seeding of prions by aggregated α-synuclein leads to transmissible spongiform encephalopathy

scientific article published on 10 August 2017

Design and construction of diverse mammalian prion strains

scientific article

Dichotomous versus palm-type mechanisms of lateral assembly of amyloid fibrils

scientific article published in June 2006

Dissecting Structure of Prion Amyloid Fibrils by Hydrogen–Deuterium Exchange Ultraviolet Raman Spectroscopy ⬇️

scientific article published on June 26, 2012

Expression and purification of full-length recombinant PrP of high purity

scientific article published in January 2008

Fast and ultrasensitive method for quantitating prion infectivity titre ⬇️

scientific article published on March 13, 2012

Genesis of mammalian prions: from non-infectious amyloid fibrils to a transmissible prion disease

scientific article (publication date: December 2011)

Genesis of tramsmissible protein states via deformed templating ⬇️

scientific article published on July 1, 2012

Hemicentin assembly in the extracellular matrix is mediated by distinct structural modules

scientific article published on 23 June 2006

Highly efficient protein misfolding cyclic amplification

scientific article (publication date: 2011)

Highly promiscuous nature of prion polymerization.

scientific article published on 16 October 2007

In vitro conversion of full-length mammalian prion protein produces amyloid form with physical properties of PrP(Sc).

scientific article published on 19 December 2004

In vitro conversion of mammalian prion protein into amyloid fibrils displays unusual features

scientific article published in February 2005

Inflammatory response of microglia to prions is controlled by sialylation of PrPSc.

scientific article published on 27 July 2018

Light-dependent electrogenic activity of cyanobacteria

scientific article

Loss of Cellular Sialidases Does Not Affect the Sialylation Status of the Prion Protein but Increases the Amounts of Its Proteolytic Fragment C1

scientific article

Methionine oxidation interferes with conversion of the prion protein into the fibrillar proteinase K-resistant conformation

scientific article

Methods for conversion of prion protein into amyloid fibrils

scientific article published in January 2008

Methods of Protein Misfolding Cyclic Amplification

scientific article

Molecular structure of amyloid fibrils controls the relationship between fibrillar size and toxicity.

scientific article

Multifaceted Role of Sialylation in Prion Diseases

scientific article

Nanostructured polypyrrole-coated anode for sun-powered microbial fuel cells

scientific article published on 20 November 2009

New Molecular Insight into Mechanism of Evolution of Mammalian Synthetic Prions

scientific article published on 9 February 2016

Nonpolar substitution at the C-terminus of the prion protein, a mimic of the glycosylphosphatidylinositol anchor, partially impairs amyloid fibril formation

scientific article

Oligomeric-induced activity by thienyl pyrimidine compounds traps prion infectivity

scientific article

Pathway complexity of prion protein assembly into amyloid

scientific article published on 23 March 2002

Photosynthetic microbial fuel cells with positive light response

scientific article published on 01 December 2009

Polymorphism and ultrastructural organization of prion protein amyloid fibrils: an insight from high resolution atomic force microscopy

scientific article published on 20 February 2006

Post-conversion sialylation of prions in lymphoid tissues

scientific article

Posttranslational modifications define course of prion strain adaptation and disease phenotype

scientific article published on 02 June 2020

PrP charge structure encodes interdomain interactions

scientific article

Preserving prion strain identity upon replication of prions in vitro using recombinant prion protein

scientific article

Prion Strain-Specific Structure and Pathology: A View from the Perspective of Glycobiology

scholarly article by Ilia V Baskakov et al published 18 December 2018 in Viruses

Prion replication environment defines the fate of prion strain adaptation.

scientific article

Probing the conformation of the prion protein within a single amyloid fibril using a novel immunoconformational assay.

scientific article

Protease-sensitive synthetic prions

scientific article

Purification and Fibrillation of Full-Length Recombinant PrP.

scientific article published in January 2017

Purification and fibrillation of full-length recombinant PrP.

scientific article published on January 2012

Recombinant prion protein induces a new transmissible prion disease in wild-type animals

scientific article

Region-Specific Response of Astrocytes to Prion Infection

scientific article published on 09 October 2019

Region-Specific Sialylation Pattern of Prion Strains Provides Novel Insight into Prion Neurotropism

scientific article published on 28 January 2020

Region-specific glial homeostatic signature in prion diseases is replaced by a uniform neuroinflammation signature, common for brain regions and prion strains with different cell tropism

scientific article published on 27 January 2020

Relationship between Conformational Stability and Amplification Efficiency of Prions ⬇️

scientific article published on August 24, 2011

Reversible off and on switching of prion infectivity via removing and reinstalling prion sialylation

scientific article

Role of the photosynthetic electron transfer chain in electrogenic activity of cyanobacteria

scientific article published on 12 April 2011

Selective Amplification of Classical and Atypical Prions Using Modified Protein Misfolding Cyclic Amplification ⬇️

scientific article published on November 20, 2012

Semiautomated cell-free conversion of prion protein: applications for high-throughput screening of potential antiprion drugs

scientific article

Sialylation Controls Prion Fate in Vivo

scientific article published on 20 December 2016

Sialylation of Glycosylphosphatidylinositol (GPI) Anchors of Mammalian Prions Is Regulated in a Host-, Tissue-, and Cell-specific Manner

scientific article published on 17 June 2016

Sialylation of prion protein controls the rate of prion amplification, the cross-species barrier, the ratio of PrPSc glycoform and prion infectivity

scientific article (publication date: September 2014)

Sialylation of the prion protein glycans controls prion replication rate and glycoform ratio

scientific article

Site-specific conformational studies of prion protein (PrP) amyloid fibrils revealed two cooperative folding domains within amyloid structure

scientific article published on 23 January 2007

Stabilization of a prion strain of synthetic origin requires multiple serial passages

scientific article

Strain-dependent profile of misfolded prion protein aggregates

scientific article published on 15 February 2016

Strain-specified characteristics of mouse synthetic prions

scientific article

Synthetic mammalian prions

scientific article

Synthetic prions generated in vitro are similar to a newly identified subpopulation of PrPSc from sporadic Creutzfeldt-Jakob Disease

scientific article published on 31 March 2005

The cellular form of the prion protein guides the differentiation of human embryonic stem cells into neuron-, oligodendrocyte-, and astrocyte-committed lineages

scientific article

The cellular form of the prion protein is involved in controlling cell cycle dynamics, self-renewal, and the fate of human embryonic stem cell differentiation.

scientific article

The diversity and relationship of prion protein self-replicating states

scientific article

The dominant-negative effect of the Q218K variant of the prion protein does not require protein X.

scientific article

The evolution of transmissible prions: the role of deformed templating

scientific article

The peculiar nature of unfolding of the human prion protein

scientific article published on 6 February 2004

The polybasic N-terminal region of the prion protein controls the physical properties of both the cellular and fibrillar forms of PrP.

scientific article

The presence of valine at residue 129 in human prion protein accelerates amyloid formation.

scientific article published on 8 April 2005

The same primary structure of the prion protein yields two distinct self-propagating states

scientific article published on 8 April 2008

The α-helical C-terminal domain of full-length recombinant PrP converts to an in-register parallel β-sheet structure in PrP fibrils: evidence from solid state nuclear magnetic resonance

scientific article

Treatment with normal prion protein delays differentiation and helps to maintain high proliferation activity in human embryonic stem cells

scientific article published on 20 January 2010

Two alternative pathways for generating transmissible prion disease de novo

scientific article

Two amyloid States of the prion protein display significantly different folding patterns

scientific article

List of works by Ilia V. Baskakov

A new mechanism for transmissible prion diseases

Amyloid features and neuronal toxicity of mature prion fibrils are highly sensitive to high pressure

Amyloid fibrils of mammalian prion protein induce axonal degeneration in NTERA2-derived terminally differentiated neurons

Analysis of Covalent Modifications of Amyloidogenic Proteins Using Two-Dimensional Electrophoresis: Prion Protein and Its Sialylation

Annealing prion protein amyloid fibrils at high temperature results in extension of a proteinase K-resistant core

Assessment of Strain-Specific PrPSc Elongation Rates Revealed a Transformation of PrPSc Properties during Protein Misfolding Cyclic Amplification ⬇️

Atomic force fluorescence microscopy in the characterization of amyloid fibril assembly and oligomeric intermediates

Atypical and classical forms of the disease-associated state of the prion protein exhibit distinct neuronal tropism, deposition patterns, and lesion profiles

Changes in prion replication environment cause prion strain mutation

Chemoenzymatic synthesis of HIV-1 V3 glycopeptides carrying two N-glycans and effects of glycosylation on the peptide domain

Conformational stability of PrP amyloid fibrils controls their smallest possible fragment size

Conformational switching within individual amyloid fibrils.

Converting the prion protein: what makes the protein infectious.

Copper(II) inhibits in vitro conversion of prion protein into amyloid fibrils.

Correction to: preserving prion strain identity upon replication of prions in vitro using recombinant prion protein

Cross-seeding of prions by aggregated α-synuclein leads to transmissible spongiform encephalopathy

Design and construction of diverse mammalian prion strains

Dichotomous versus palm-type mechanisms of lateral assembly of amyloid fibrils

Dissecting Structure of Prion Amyloid Fibrils by Hydrogen–Deuterium Exchange Ultraviolet Raman Spectroscopy ⬇️

Expression and purification of full-length recombinant PrP of high purity

Fast and ultrasensitive method for quantitating prion infectivity titre ⬇️

Genesis of mammalian prions: from non-infectious amyloid fibrils to a transmissible prion disease

Genesis of tramsmissible protein states via deformed templating ⬇️

Hemicentin assembly in the extracellular matrix is mediated by distinct structural modules

Highly efficient protein misfolding cyclic amplification

Highly promiscuous nature of prion polymerization.

In vitro conversion of full-length mammalian prion protein produces amyloid form with physical properties of PrP(Sc).

In vitro conversion of mammalian prion protein into amyloid fibrils displays unusual features

Inflammatory response of microglia to prions is controlled by sialylation of PrPSc.

Light-dependent electrogenic activity of cyanobacteria

Loss of Cellular Sialidases Does Not Affect the Sialylation Status of the Prion Protein but Increases the Amounts of Its Proteolytic Fragment C1

Methionine oxidation interferes with conversion of the prion protein into the fibrillar proteinase K-resistant conformation

Methods for conversion of prion protein into amyloid fibrils

Methods of Protein Misfolding Cyclic Amplification

Molecular structure of amyloid fibrils controls the relationship between fibrillar size and toxicity.

Multifaceted Role of Sialylation in Prion Diseases

Nanostructured polypyrrole-coated anode for sun-powered microbial fuel cells

New Molecular Insight into Mechanism of Evolution of Mammalian Synthetic Prions

Nonpolar substitution at the C-terminus of the prion protein, a mimic of the glycosylphosphatidylinositol anchor, partially impairs amyloid fibril formation

Oligomeric-induced activity by thienyl pyrimidine compounds traps prion infectivity

Pathway complexity of prion protein assembly into amyloid

Photosynthetic microbial fuel cells with positive light response

Polymorphism and ultrastructural organization of prion protein amyloid fibrils: an insight from high resolution atomic force microscopy

Post-conversion sialylation of prions in lymphoid tissues

Posttranslational modifications define course of prion strain adaptation and disease phenotype

PrP charge structure encodes interdomain interactions

Preserving prion strain identity upon replication of prions in vitro using recombinant prion protein

Prion Strain-Specific Structure and Pathology: A View from the Perspective of Glycobiology

Prion replication environment defines the fate of prion strain adaptation.

Probing the conformation of the prion protein within a single amyloid fibril using a novel immunoconformational assay.

Protease-sensitive synthetic prions

Purification and Fibrillation of Full-Length Recombinant PrP.

Purification and fibrillation of full-length recombinant PrP.

Recombinant prion protein induces a new transmissible prion disease in wild-type animals

Region-Specific Response of Astrocytes to Prion Infection

Region-Specific Sialylation Pattern of Prion Strains Provides Novel Insight into Prion Neurotropism

Region-specific glial homeostatic signature in prion diseases is replaced by a uniform neuroinflammation signature, common for brain regions and prion strains with different cell tropism

Relationship between Conformational Stability and Amplification Efficiency of Prions ⬇️

Reversible off and on switching of prion infectivity via removing and reinstalling prion sialylation

Role of the photosynthetic electron transfer chain in electrogenic activity of cyanobacteria

Selective Amplification of Classical and Atypical Prions Using Modified Protein Misfolding Cyclic Amplification ⬇️

Semiautomated cell-free conversion of prion protein: applications for high-throughput screening of potential antiprion drugs

Sialylation Controls Prion Fate in Vivo

Sialylation of Glycosylphosphatidylinositol (GPI) Anchors of Mammalian Prions Is Regulated in a Host-, Tissue-, and Cell-specific Manner

Sialylation of prion protein controls the rate of prion amplification, the cross-species barrier, the ratio of PrPSc glycoform and prion infectivity

Sialylation of the prion protein glycans controls prion replication rate and glycoform ratio

Site-specific conformational studies of prion protein (PrP) amyloid fibrils revealed two cooperative folding domains within amyloid structure

Stabilization of a prion strain of synthetic origin requires multiple serial passages

Strain-dependent profile of misfolded prion protein aggregates

Strain-specified characteristics of mouse synthetic prions

Synthetic mammalian prions

Synthetic prions generated in vitro are similar to a newly identified subpopulation of PrPSc from sporadic Creutzfeldt-Jakob Disease

The cellular form of the prion protein guides the differentiation of human embryonic stem cells into neuron-, oligodendrocyte-, and astrocyte-committed lineages

The cellular form of the prion protein is involved in controlling cell cycle dynamics, self-renewal, and the fate of human embryonic stem cell differentiation.

The diversity and relationship of prion protein self-replicating states

The dominant-negative effect of the Q218K variant of the prion protein does not require protein X.

The evolution of transmissible prions: the role of deformed templating

The peculiar nature of unfolding of the human prion protein

The polybasic N-terminal region of the prion protein controls the physical properties of both the cellular and fibrillar forms of PrP.