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List of works by Zhenyu Yue

A Role for Autophagic Protein Beclin 1 Early in Lymphocyte Development ⬇️

scientific article published on January 14, 2011

A novel protein complex linking the delta 2 glutamate receptor and autophagy: implications for neurodegeneration in lurcher mice

scientific article (publication date: 29 August 2002)

ALS-FTLD-linked mutations of SQSTM1/p62 disrupt selective autophagy and NFE2L2/NRF2 anti-oxidative stress pathway

scientific article published on 30 July 2019

Assessment of chloroquine treatment for modulating autophagy flux in brain of WT and HD mice

scientific article published on January 2014

Atg14L and Rubicon: yin and yang of Beclin 1-mediated autophagy control

scientific article published on 3 August 2009

Autophagy Receptors and Neurodegenerative Diseases

scientific article published on 3 February 2017

Autophagy and its normal and pathogenic states in the brain

scientific article published on 21 April 2014

Autophagy in axonal and dendritic degeneration

scientific article published on 30 April 2013

Autophagy in ischemic stroke

scientific article published on 10 January 2018

Autophagy in neurodegenerative diseases

scientific article published in October 2016

Autophagy is a gatekeeper of hepatic differentiation and carcinogenesis by controlling the degradation of Yap

scientific article published in Nature Communications

Autophagy is induced upon platelet activation and is essential for hemostasis and thrombosis.

scientific article

Autophagy modulator scoring system: a user-friendly tool for quantitative analysis of methodological integrity of chemical autophagy modulator studies

scientific article published on 23 December 2019

Autophagy of the Nervous System

article published in 2011

Autophagy protein NRBF2 has reduced expression in Alzheimer's brains and modulates memory and amyloid-beta homeostasis in mice

scientific article published on 27 November 2019

Autophagy releases lipid that promotes fibrogenesis by activated hepatic stellate cells in mice and in human tissues.

scientific article

B1 is involved in autophagy inhibition caused by SNCA/a-synuclein overexpression: a process modulated by the natural autophagy inducer corynoxine B.

scientific article published in September 2015

Beclin 1 is required for neuron viability and regulates endosome pathways via the UVRAG-VPS34 complex

scientific article (publication date: October 2014)

Beclin 1, an autophagy gene essential for early embryonic development, is a haploinsufficient tumor suppressor

scientific article

CSF-1 controls cerebellar microglia and is required for motor function and social interaction

scientific article published on 26 July 2019

Cell "self-eating" (autophagy) mechanism in Alzheimer's disease

scientific article published on January 2010

Correction: Phosphorylation-Dependent 14-3-3 Binding to LRRK2 Is Impaired by Common Mutations of Familial Parkinson's Disease.

scientific article published on 21 July 2011

Deregulation of autophagy and vesicle trafficking in Parkinson's disease

scientific article published on 05 April 2018

Diminished autophagy limits cardiac injury in mouse models of type 1 diabetes

scientific article published on 08 May 2013

Disentangling the Molecular Pathways of Parkinson's Disease using Multiscale Network Modeling

scientific article published on 24 December 2020

Disrupted autophagy leads to dopaminergic axon and dendrite degeneration and promotes presynaptic accumulation of α-synuclein and LRRK2 in the brain

scientific article

Distinct regulation of autophagic activity by Atg14L and Rubicon associated with Beclin 1-phosphatidylinositol-3-kinase complex

scientific article

Enhancing depression mechanisms in midbrain dopamine neurons achieves homeostatic resilience

scientific article

Essential role for autophagy protein Atg7 in the maintenance of axonal homeostasis and the prevention of axonal degeneration

scientific journal article

Functional variants in the LRRK2 gene confer shared effects on risk for Crohn's disease and Parkinson's disease

scientific article published in January 2018

Gammaherpesvirus 68 Infection of Endothelial Cells Requires both Host Autophagy Genes and Viral Oncogenes for Optimal Survival and Persistence ⬇️

scientific article published on April 13, 2011

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

scientific article

Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition)

article by Daniel J Klionsky et al published January 2021 in Autophagy

Guidelines for the use and interpretation of assays for monitoring autophagy in higher eukaryotes

scientific article

HMGB1 is involved in autophagy inhibition caused by SNCA/α-synuclein overexpression: a process modulated by the natural autophagy inducer corynoxine B.

scientific article

Homeostatic levels of p62 control cytoplasmic inclusion body formation in autophagy-deficient mice

scientific article

Identification of breast cancer candidate genes using gene co-expression and protein-protein interaction information

scientific article published on 02 May 2016

Impaired autophagy in neurons after disinhibition of mammalian target of rapamycin and its contribution to epileptogenesis

scientific article

Imperfect interface of Beclin1 coiled-coil domain regulates homodimer and heterodimer formation with Atg14L and UVRAG

scientific article

Induction of autophagy in axonal dystrophy and degeneration

scientific journal article

Is amyotrophic lateral sclerosis/frontotemporal dementia an autophagy disease?

scientific article published on 28 December 2017

Latrepirdine (dimebon) enhances autophagy and reduces intracellular GFP-Aβ42 levels in yeast.

scientific article published on January 2012

Leucine-rich repeat kinase 2 (LRRK2)/PARK8 possesses GTPase activity that is altered in familial Parkinson's disease R1441C/G mutants

scientific article published on 10 July 2007

Loss of mTOR-Dependent Macroautophagy Causes Autistic-like Synaptic Pruning Deficits

scholarly article by Guomei Tang et al published September 2014 in Neuron

Loss of mTOR-dependent macroautophagy causes autistic-like synaptic pruning deficits

scientific article (publication date: 3 September 2014)

Low-variance RNAs identify Parkinson's disease molecular signature in blood

scientific article published on 18 March 2015

MTORC1-mediated NRBF2 phosphorylation functions as a switch for the class III PtdIns3K and autophagy

scientific article published on 6 January 2017

Molecular definitions of autophagy and related processes.

scientific article published on 08 June 2017

NRBF2 is a RAB7 effector required for autophagosome maturation and mediates the association of APP-CTFs with active form of RAB7 for degradation

scientific article published on 16 June 2020

NRBF2 is involved in the autophagic degradation process of APP-CTFs in Alzheimer disease models.

scientific article published on 5 October 2017

NRBF2 regulates autophagy and prevents liver injury by modulating Atg14L-linked phosphatidylinositol-3 kinase III activity

scientific article

Neuronal autophagy: going the distance to the axon.

scientific article published on 23 October 2007

Neuronal vulnerability in Parkinson disease: Should the focus be on axons and synaptic terminals?

scientific article published on 04 September 2019

Nigericin-induced impairment of autophagic flux in neuronal cells is inhibited by overexpression of Bak.

scientific article

PI3KC3 complex subunit NRBF2 is required for apoptotic cell clearance to restrict intestinal inflammation

scientific article published on 19 March 2020

Phosphorylation-dependent 14-3-3 binding to LRRK2 is impaired by common mutations of familial Parkinson's disease

scientific journal article

Progress in LRRK2-Associated Parkinson's Disease Animal Models

scientific article published on 15 July 2020

Proteotoxic stress induces phosphorylation of p62/SQSTM1 by ULK1 to regulate selective autophagic clearance of protein aggregates

scientific article

Selective association of neurogranin gene expression with amyloid and tau pathology in the parahippocampal gyrus in Alzheimer’s disease

scientific article published in 2020

Short- and long-term effects of LRRK2 on axon and dendrite growth

scientific article

Structural model of the dimeric Parkinson's protein LRRK2 reveals a compact architecture involving distant interdomain contacts

scientific journal article

Synaptotagmin-11 is a critical mediator of parkin-linked neurotoxicity and Parkinson's disease-like pathology

scientific article published on 8 January 2018

Synj1 Haploinsufficiency Causes Dopamine Neuron Vulnerability and alpha-synuclein Accumulation in Mice

scientific article published on 30 April 2020

Targeting the potent Beclin 1-UVRAG coiled-coil interaction with designed peptides enhances autophagy and endolysosomal trafficking.

scientific article

Tau accumulation impairs mitophagy via increasing mitochondrial membrane potential and reducing mitochondrial Parkin

scientific article published on 02 March 2016

The BECN1 coiled coil domain: an "imperfect" homodimer interface that facilitates ATG14 and UVRAG binding

scientific article published on 31 May 2012

The Beclin 1-VPS34 complex--at the crossroads of autophagy and beyond

scientific article

The P2RY12 receptor promotes VSMC-derived foam cell formation by inhibiting autophagy in advanced atherosclerosis

scientific article published on 19 March 2020

The Parkinson's Disease-Associated Mutation LRRK2-G2019S Impairs Synaptic Plasticity in Mouse Hippocampus

scientific article

The cellular pathways of neuronal autophagy and their implication in neurodegenerative diseases

scientific article published on 06 February 2009

The class IA phosphatidylinositol 3-kinase p110-β subunit is a positive regulator of autophagy ⬇️

scientific article published on November 8, 2010

The landscape of multiscale transcriptomic networks and key regulators in Parkinson's disease

scientific article published on 20 November 2019

The role of genetics in Parkinson's disease: a large cohort study in Chinese mainland population

scientific article published on 02 July 2020

Transformative Network Modeling of Multi-omics Data Reveals Detailed Circuits, Key Regulators, and Potential Therapeutics for Alzheimer's Disease

scientific article published on 17 November 2020

ULK1-mediated phosphorylation of ATG14 promotes autophagy and is impaired in Huntington's disease models

scientific article published on 09 December 2016

Using genetic mouse models to study the biology and pathology of autophagy in the central nervous system.

scientific article published in January 2009

Vitamin B12 modulates Parkinson's disease LRRK2 kinase activity through allosteric regulation and confers neuroprotection

scientific article published on 11 March 2019

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