List of works by Gene E. Alexander

3D characterization of brain atrophy in Alzheimer's disease and mild cognitive impairment using tensor-based morphometry

scientific article published on 21 February 2008

A distinctive interaction between chronic anxiety and problem solving in asymptomatic APOE e4 homozygotes.

scientific article published in January 2004

A distinctive interaction between memory and chronic daytime somnolence in asymptomatic APOE e4 homozygotes.

scientific article published in June 2002

A preliminary fluorodeoxyglucose positron emission tomography study in healthy adults reporting dream-enactment behavior

scientific article published in July 2006

Abnormal brain glucose metabolism in the delusional misidentification syndromes: a positron emission tomography study in Alzheimer disease.

scientific article published in October 1995

Accurate measurement of brain changes in longitudinal MRI scans using tensor-based morphometry

scientific article

Adult fragile X syndrome: neuropsychology, brain anatomy, and metabolism.

scientific article published in December 1995

Age transformation of combined hippocampus and amygdala volume improves diagnostic accuracy in Alzheimer's disease

scientific article published in February 2002

Age-Related Regional Network Covariance of Magnetic Resonance Imaging Gray Matter in the Rat

scientific article published on 26 August 2020

Age-related cortical grey matter reductions in non-demented Down's syndrome adults determined by MRI with voxel-based morphometry.

scientific article

Age-related differences in visual perception: a PET study

scientific article published on 01 July 2000

Age-related networks of regional covariance in MRI gray matter: reproducible multivariate patterns in healthy aging

scientific article published on 28 September 2009

Age-related regional network of magnetic resonance imaging gray matter in the rhesus macaque.

scientific article published in March 2008

Alzheimer's disease neuroimaging initiative: a one-year follow up study using tensor-based morphometry correlating degenerative rates, biomarkers and cognition

scientific article published on April 2009

An automated algorithm for the computation of brain volume change from sequential MRIs using an iterative principal component analysis and its evaluation for the assessment of whole-brain atrophy rates in patients with probable Alzheimer's disease

scientific article published on May 2004

An automated normative-based fluorodeoxyglucose positron emission tomography image-analysis procedure to aid Alzheimer disease diagnosis using statistical parametric mapping and interactive image display

article

Apolipoprotein E and intellectual achievement

scientific article published on 01 January 2002

Assessing the reliability to detect cerebral hypometabolism in probable Alzheimer's disease and amnestic mild cognitive impairment

scientific article

Association between an Alzheimer's Disease-Related Index and APOE ε4 Gene Dose

scientific article

Association between brain functional failure and dementia severity in Alzheimer's disease: resting versus stimulation PET study.

scientific article published in March 1999

Association of common genetic variants in GPCPD1 with scaling of visual cortical surface area in humans

scientific article published on 16 February 2012

Biomarker Based Diagnosis Of Very Mild Alzheimer'S Disease: A Multicenter Study

article

Blood Pressure Control in Aging Predicts Cerebral Atrophy Related to Small-Vessel White Matter Lesions

scientific article

Brain cognition and metabolism in Down syndrome adults in association with development of dementia.

scientific article published in November 1996

Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study

scientific article

Brain metabolite concentration and dementia severity in Alzheimer's disease: a (1)H MRS study

scientific article published in August 2001

Categorical and correlational analyses of baseline fluorodeoxyglucose positron emission tomography images from the Alzheimer's Disease Neuroimaging Initiative (ADNI).

scientific article

Cerebral blood flow patterns underlying the differential impairment in category vs letter fluency in Alzheimer's disease.

scientific article published in October 1999

Cerebral metabolic response to passive audiovisual stimulation in patients with Alzheimer's disease and healthy volunteers assessed by PET.

scientific article published in April 2000

Challenges and opportunities for characterizing cognitive aging across species

scientific article

Characterizing Alzheimer's disease using a hypometabolic convergence index

scientific article

Characterizing cognitive aging in humans with links to animal models

scientific article

Characterizing cognitive aging of working memory and executive function in animal models

scientific article published on 12 September 2012

Cholesterol-related genetic risk scores are associated with hypometabolism in Alzheimer's-affected brain regions

scientific article published on 17 January 2008

Cholinergic enhancement improves performance on working memory by modulating the functional activity in distinct brain regions: a positron emission tomography regional cerebral blood flow study in healthy humans.

scientific article published in February 2000

Cholinergic stimulation alters performance and task-specific regional cerebral blood flow during working memory

scientific article

Cognitive domain decline in healthy apolipoprotein E epsilon4 homozygotes before the diagnosis of mild cognitive impairment.

scientific article published in September 2007

Cognitive performance in older women relative to ApoE-epsilon4 genotype and aerobic fitness.

scientific article published in January 2007

Comparing 3 T and 1.5 T MRI for tracking Alzheimer's disease progression with tensor-based morphometry

scientific article

Contributions of Hippocampal Volume to Cognition in Healthy Older Adults

scientific article published on 05 November 2020

Corpus callosum atrophy is a possible indicator of region- and cell type-specific neuronal degeneration in Alzheimer disease: a magnetic resonance imaging analysis

scientific article

Corpus callosum measurement as an in vivo indicator for neocortical neuronal integrity, but not white matter pathology, in Alzheimer's disease.

scientific article published in April 2000

Correlating cerebral hypometabolism with future memory decline in subsequent converters to amnestic pre-mild cognitive impairment

scientific article published on September 2008

Correlations between FDG PET glucose uptake-MRI gray matter volume scores and apolipoprotein E ε4 gene dose in cognitively normal adults: a cross-validation study using voxel-based multi-modal partial least squares

scientific article published on 12 February 2012

Correlations between apolipoprotein E epsilon4 gene dose and brain-imaging measurements of regional hypometabolism

scientific article

Correlations between apolipoprotein E epsilon4 gene dose and whole brain atrophy rates

scientific article

Cortical perfusion and gray matter weight in frontal lobe dementia

scientific article published in January 1995

Differences between young and older adults in unity and diversity of executive functions

scientific article published on 08 October 2020

Differences in Resting State Functional Connectivity between Young Adult Endurance Athletes and Healthy Controls

scientific article

Dissociation between corpus callosum atrophy and white matter pathology in Alzheimer's disease

scientific article published in November 1998

Effects of simultaneous cognitive and aerobic exercise training on dual-task walking performance in healthy older adults: results from a pilot randomized controlled trial

scientific article published on 02 March 2020

Evidence for an association between KIBRA and late-onset Alzheimer's disease

scientific article

Fibrillar amyloid-beta burden in cognitively normal people at 3 levels of genetic risk for Alzheimer's disease

scholarly article

Frequency Variation of a Pattern-Flash Visual Stimulus during PET Differentially Activates Brain from Striate through Frontal Cortex

scientific article

Functional brain abnormalities in young adults at genetic risk for late-onset Alzheimer's dementia

scientific article (publication date: 19 December 2003)

GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers

scientific article

Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain

scientific article

Gradual hypertension induction in middle-aged Cyp1a1-Ren2 transgenic rats produces significant impairments in spatial learning

article

Gray matter network associated with risk for Alzheimer's disease in young to middle-aged adults

scientific article

Heterogeneous data fusion for alzheimer's disease study

article

High brain myo-inositol levels in the predementia phase of Alzheimer's disease in adults with Down's syndrome: a 1H MRS study

scientific article published on 01 December 1999

Higher serum glucose levels are associated with cerebral hypometabolism in Alzheimer regions

scientific article published on 27 March 2013

Higher serum total cholesterol levels in late middle age are associated with glucose hypometabolism in brain regions affected by Alzheimer's disease and normal aging

scientific article

Hypometabolism in Alzheimer-affected brain regions in cognitively healthy Latino individuals carrying the apolipoprotein E epsilon4 allele

scientific article

Imaging systems level consolidation of novel associate memories: a longitudinal neuroimaging study

scientific article

Impaired platelet mitochondrial activity in Alzheimer's disease and mild cognitive impairment

scientific article published on 27 October 2006

In vivo imaging of region and cell type specific neocortical neurodegeneration in Alzheimer's disease. Perspectives of MRI derived corpus callosum measurement for mapping disease progression and effects of therapy. Evidence from studies with MRI, EE

scientific article

Increasing required neural response to expose abnormal brain function in mild versus moderate or severe Alzheimer's disease: PET study using parametric visual stimulation

scientific article published in June 1998

Independent Contributions of Dorsolateral Prefrontal Structure and Function to Working Memory in Healthy Older Adults

scientific article published on 14 November 2020

Individual differences in PET activation of object perception and attention systems predict face matching accuracy

scientific article

Inferior parietal perfusion, lateralization, and neuropsychological dysfunction in Alzheimer's disease

scientific article published in December 1996

Intensity non-uniformity correction using N3 on 3-T scanners with multichannel phased array coils

scientific article published on 30 October 2007

Interaction of Age and Self-reported Physical Sports Activity on White Matter Hyperintensity Volume in Healthy Older Adults

scientific article published on 02 November 2020

Interactive Effects of Age and Hypertension on Volumes of Brain Structures ⬇️

scientific article published on July 1, 1997

Inverse relationship between education and parietotemporal perfusion deficit in Alzheimer's disease

scientific article published in September 1992

Linking functional and structural brain images with multivariate network analyses: a novel application of the partial least square method

scientific article published on 23 April 2009

Longitudinal PET Evaluation of Cerebral Metabolic Decline in Dementia: A Potential Outcome Measure in Alzheimer's Disease Treatment Studies

scientific article published on May 2002

Longitudinal modeling of age-related memory decline and the APOE epsilon4 effect

scientific article

Longitudinal stability of MRI for mapping brain change using tensor-based morphometry

scientific article published on 15 February 2006

Low glucose metabolism during brain stimulation in older Down's syndrome subjects at risk for Alzheimer's disease prior to dementia.

scientific article published in August 1997

MRI Template and Atlas Toolbox for the C57BL/6J Mouse Brain

Mapping Alzheimer's disease progression in 1309 MRI scans: power estimates for different inter-scan intervals

scientific article

Network analysis of single-subject fMRI during a finger opposition task

scientific article

Optimizing power to track brain degeneration in Alzheimer's disease and mild cognitive impairment with tensor-based morphometry: an ADNI study of 515 subjects

scientific article

PET reveals occipitotemporal pathway activation during elementary form perception in humans

scientific article published on 01 May 1998

Peripheral delivery of a ROCK inhibitor improves learning and working memory

scientific article

Positron emission tomography in evaluation of dementia: Regional brain metabolism and long-term outcome

scientific article published in November 2001

Posterior cingulate glucose metabolism, hippocampal glucose metabolism, and hippocampal volume in cognitively normal, late-middle-aged persons at 3 levels of genetic risk for Alzheimer disease

scientific article published on March 2013

Preclinical cognitive decline in late middle-aged asymptomatic apolipoprotein E-e4/4 homozygotes: a replication study.

scientific article

Predicting Imminent Progression to Clinically Significant Memory Decline Using Volumetric MRI and FDG PET.

scientific article

Prediction of conversion from mild cognitive impairment to Alzheimer's disease dementia based upon biomarkers and neuropsychological test performance

scientific article published on 14 December 2010

Preferential metabolic involvement of visual cortical areas in a subtype of Alzheimer's disease: clinical implications.

scientific article published in October 1996

Progression of corpus callosum atrophy in Alzheimer disease

scientific article published in February 2002

Region-specific corpus callosum atrophy correlates with the regional pattern of cortical glucose metabolism in Alzheimer disease

scientific article published in April 1999

Regional cerebral blood flow in Down syndrome adults during the Wisconsin Card Sorting Test: exploring cognitive activation in the context of poor performance

scientific article

Regional glucose metabolic abnormalities are not the result of atrophy in Alzheimer's disease.

scientific article published in June 1998

Regional network of magnetic resonance imaging gray matter volume in healthy aging

scientific article published in July 2006

Regional pattern of hippocampus and corpus callosum atrophy in Alzheimer's disease in relation to dementia severity: evidence for early neocortical degeneration

scientific article

Relation of age and apolipoprotein E to cognitive function in Down syndrome adults ⬇️

scientific article published on May 27, 1997

Relation of corpus callosum and hippocampal size to age in nondemented adults with Down's syndrome

scientific article published in October 2003

Relation of medial temporal lobe volumes to age and memory function in nondemented adults with Down's syndrome: implications for the prodromal phase of Alzheimer's disease.

scientific article published in January 2002

Relationship between lifetime occupation and parietal flow: implications for a reserve against Alzheimer's disease pathology

scientific article published on 01 January 1995

Resting state brain glucose metabolism is not reduced in normotensive healthy men during aging, after correction for brain atrophy

scientific article

Right hippocampal volume mediation of subjective memory complaints differs by hypertension status in healthy aging

scientific article published on 19 June 2020

Separating lexical-semantic access from other mnemonic processes in picture-name verification

scientific article

Sparse Inverse Covariance Analysis of human brain for Alzheimer's disease study

article

Structural Neural Correlates of Double Decision Performance in Older Adults

scientific article published on 02 September 2020

The Alzheimer's Disease Neuroimaging Initiative (ADNI): MRI methods

scientific article

The Role of Resting-State Network Functional Connectivity in Cognitive Aging

scientific article published on 12 June 2020

The effect of brain atrophy on cerebral hypometabolism in the visual variant of Alzheimer disease

scientific article published in March 2001

The metabolic topography of normal aging

scientific article published on May 1996

The neurometabolic landscape of cognitive decline: in vivo studies with positron emission tomography in Alzheimer's disease.

scientific article

Time course of pharmacodynamic and pharmacokinetic effects of physostigmine assessed by functional brain imaging in humans.

scientific article

Tracking the decline in cerebral glucose metabolism in persons and laboratory animals at genetic risk for Alzheimer's disease

article

Twelve-month metabolic declines in probable Alzheimer's disease and amnestic mild cognitive impairment assessed using an empirically pre-defined statistical region-of-interest: findings from the Alzheimer's Disease Neuroimaging Initiative

scientific article

Visual cortical dysfunction in Alzheimer's disease evaluated with a temporally graded "stress test" during PET.

scientific article published in January 1996

Visual variant of Alzheimer's disease: Distinctive neuropsychological features

article

Volumes of medial temporal lobe structures in patients with Alzheimer's disease and mild cognitive impairment (and in healthy controls).

scientific article published in January 1998

WAIS-R subtest profile and cortical perfusion in Alzheimer's disease

scientific article

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