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List of works by M. Flint Beal

1-Methyl-4-phenyl-1,2,3,6-tetrahydropyride neurotoxicity is attenuated in mice overexpressing Bcl-2.

scientific article published in October 1998

1-Methyl-4-phenylpyridinium produces excitotoxic lesions in rat striatum as a result of impairment of oxidative metabolism.

scientific article

2-Chloroadenosine attenuates NMDA, kainate, and quisqualate toxicity

scientific article published in May 1991

3-Nitropropionic acid neurotoxicity is attenuated in copper/zinc superoxide dismutase transgenic mice

scientific article published on 01 August 1995

3-Nitropropionic acid-induced neurotoxicity--assessed by ultra high resolution positron emission tomography with comparison to magnetic resonance spectroscopy

scientific article

3‐Nitropropionic Acid Toxicity in the Striatum ⬇️

scientific article published on 01 November 1994

A carbon column-based liquid chromatography electrochemical approach to routine 8-hydroxy-2'-deoxyguanosine measurements in urine and other biologic matrices: a one-year evaluation of methods

scientific article published on 01 September 1999

A neuroprotective role of the human uncoupling protein 2 (hUCP2) in a Drosophila Parkinson's Disease model ⬇️

scientific article published on January 13, 2012

A novel azulenyl nitrone antioxidant protects against MPTP and 3-nitropropionic acid neurotoxicities

scientific article published in January 2005

A novel intracellular role of matrix metalloproteinase-3 during apoptosis of dopaminergic cells

scientific article

A novel systemically active caspase inhibitor attenuates the toxicities of MPTP, malonate, and 3NP in vivo

scientific article published in November 2004

A pivotal role of matrix metalloproteinase-3 activity in dopaminergic neuronal degeneration via microglial activation

scientific article published on 20 November 2006

A randomized clinical trial of high-dosage coenzyme Q10 in early Parkinson disease: no evidence of benefit

scientific article published on May 2014

A randomized study of the bioavailability of different formulations of coenzyme Q(10) (ubiquinone)

scientific article published on 09 October 2007

A role of mitochondrial complex II defects in genetic models of Huntington's disease expressing N-terminal fragments of mutant huntingtin

scientific article published on 29 May 2013

Aberrant regulation of the GSK-3β/NRF2 axis unveils a novel therapy for adrenoleukodystrophy

scientific article published on 01 August 2018

Absence of p53: no effect in a transgenic mouse model of familial amyotrophic lateral sclerosis

scientific article published on 01 September 2000

Activation of sirtuin 1 as therapy for the peroxisomal disease adrenoleukodystrophy.

scientific article

Acute and long‐term response of dopamine nigrostriatal synapses to a single, low‐dose episode of 3‐nitropropionic acid‐mediated chemical hypoxia ⬇️

scientific article published on October 8, 2010

Additive neuroprotective effects of a histone deacetylase inhibitor and a catalytic antioxidant in a transgenic mouse model of amyotrophic lateral sclerosis

scientific article

Additive neuroprotective effects of creatine and a cyclooxygenase 2 inhibitor against dopamine depletion in the 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) mouse model of Parkinson's disease.

scientific article

Additive neuroprotective effects of creatine and cyclooxygenase 2 inhibitors in a transgenic mouse model of amyotrophic lateral sclerosis

scientific article

Age and sex influence on oxidative damage and functional status in human skeletal muscle

scientific article published in January 2001

Age-dependent vulnerability of the striatum to the mitochondrial toxin 3-nitropropionic acid.

scientific article published in January 1993

Age-related microglial activation in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)-induced dopaminergic neurodegeneration in C57BL/6 mice

scientific article

Alterations of striatal neurons in benign hereditary chorea

scientific article published in October 2005

Altered succinylation of mitochondrial proteins, APP and tau in Alzheimer's disease

scientific article published on 10 January 2022

Alzheimer's APP mangles mitochondria

scientific article published on 01 November 2006

Alzheimer's brains harbor somatic mtDNA control-region mutations that suppress mitochondrial transcription and replication

scholarly article

Amino acid neurotransmitters in postmortem human brain analyzed by high performance liquid chromatography with electrochemical detection

scientific article published on 01 April 1987

Aminooxyacetic acid striatal lesions attenuated by 1,3-butanediol and coenzyme Q10.

scientific article published on August 1994

Amyloid beta, mitochondrial dysfunction and synaptic damage: implications for cognitive decline in aging and Alzheimer's disease

scientific article published on 22 January 2008

An examination of neuropeptide Y postmortem stability in an animal model simulating human autopsy conditions

scientific article published in February 1986

An in vivo model for the neurodegenerative effects of beta amyloid and protection by substance P ⬇️

scientific article published on August 15, 1991

Antioxidants in Huntington's disease ⬇️

scientific article published on November 23, 2011

Apocynin administration does not improve behavioral and neuropathological deficits in a transgenic mouse model of Alzheimer's disease ⬇️

scientific article published on February 12, 2011

Are mitochondria critical in the pathogenesis of Alzheimer's disease?

scientific article published on 19 April 2005

Aspergillosis of the nervous system

scientific article published on 01 May 1982

Attenuation of MPTP neurotoxicity by rolipram, a specific inhibitor of phosphodiesterase IV.

scientific article published on 27 February 2007

Autophagy in neurodegenerative disorders: pathogenic roles and therapeutic implications ⬇️

scientific article published on October 12, 2010

Basic fibroblast growth factor protects against excitotoxicity and chemical hypoxia in both neonatal and adult rats

scientific article published on 01 July 1995

Basic fibroblast growth factor protects against hypoxia-ischemia and NMDA neurotoxicity in neonatal rats

scientific article published in March 1993

Behavioral deficits and progressive neuropathology in progranulin-deficient mice: a mouse model of frontotemporal dementia ⬇️

scientific article published on July 28, 2010

Behavioral improvement after chronic administration of coenzyme Q10 in P301S transgenic mice

scientific article published on January 2012

Beneficial effects of creatine, CoQ10, and lipoic acid in mitochondrial disorders

scientific article

Benfotiamine treatment activates the Nrf2/ARE pathway and is neuroprotective in a transgenic mouse model of tauopathy

scientific article published on 01 August 2018

Beta-amyloid 42 accumulation in the lumbar spinal cord motor neurons of amyotrophic lateral sclerosis patients

scientific article

Beta-endorphin and somatostatin concentrations in the ventricular cerebrospinal fluid of patients with affective disorder

scientific article published on 01 September 1986

Bezafibrate administration improves behavioral deficits and tau pathology in P301S mice ⬇️

scientific article published on August 24, 2012

Bioenergetic abnormalities in discrete cerebral motor pathways presage spinal cord pathology in the G93A SOD1 mouse model of ALS.

scientific article

Bioenergetic approaches for neuroprotection in Parkinson's disease

scientific article

Bioenergetics in Huntington's disease

scientific article

Biomarkers of Parkinson's disease and Dementia with Lewy bodies ⬇️

scientific article published on September 19, 2011

Brain energy rescue: an emerging therapeutic concept for neurodegenerative disorders of ageing

scientific article published on 24 July 2020

CAG expansion affects the expression of mutant Huntingtin in the Huntington's disease brain

scientific article

CSF cyclic nucleotides and somatostatin in Parkinson's disease

scientific article published on 01 January 1986

Caspase-9 activation results in downstream caspase-8 activation and bid cleavage in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced Parkinson's disease

scientific article (publication date: 15 December 2001)

Catecholamine uptake, accumulation, and release in acute porphyria ⬇️

scientific article published on November 1, 1977

Cause and consequence: mitochondrial dysfunction initiates and propagates neuronal dysfunction, neuronal death and behavioral abnormalities in age-associated neurodegenerative diseases.

scientific article published on 26 August 2009

Celastrol blocks neuronal cell death and extends life in transgenic mouse model of amyotrophic lateral sclerosis

scientific article published on 01 January 2005

Celastrol protects against MPTP- and 3-nitropropionic acid-induced neurotoxicity.

scientific article published in August 2005

Cell-permeable peptide antioxidants as a novel therapeutic approach in a mouse model of amyotrophic lateral sclerosis

scientific article published on 01 August 2006

Cerebral Atheromatous Embolism Following Carotid Sinus Pressure ⬇️

scientific article published on 01 May 1981

Cerebral synthesis and release of kynurenic acid: an endogenous antagonist of excitatory amino acid receptors.

scientific article published on September 1990

Cerebral vein thrombosis and multiple intracranial hemorrhages by computed tomography

scientific article published on 01 July 1982

Changes of Coenzyme A and Acetyl-Coenzyme A Concentrations in Rats after a Single-Dose Intraperitoneal Injection of Hepatotoxic Thioacetamide Are Not Consistent with Rapid Recovery

scientific article published on 24 November 2020

Characterization of a Parkinson's disease rat model using an upgraded paraquat exposure paradigm

scientific article published on 20 January 2020

Chemotherapy for the brain: the antitumor antibiotic mithramycin prolongs survival in a mouse model of Huntington's disease

scientific article published on November 2004

Cholecystokinin and somatostatin in Alzheimer's disease postmortem cerebral cortex ⬇️

scientific article published on May 1, 1991

Cholesterol embolism as a cause of transient ischemic attacks and cerebral infarction

scientific article published on 01 July 1981

Chronic 3-nitropropionic acid treatment in baboons replicates the cognitive and motor deficits of Huntington's disease

scientific article published in May 1996

Chronic mitochondrial energy impairment produces selective striatal degeneration and abnormal choreiform movements in primates

scientific article

Chronic quinolinic acid lesions in rats closely resemble Huntington's disease ⬇️

scientific article published on June 1, 1991

Clinically approved heterocyclics act on a mitochondrial target and reduce stroke-induced pathology.

scientific article published in July 2004

Coenzyme Q 10 administration increases brain mitochondrial concentrations and exerts neuroprotective effects ⬇️

scientific article published on July 21, 1998

Coenzyme Q10 and nicotinamide and a free radical spin trap protect against MPTP neurotoxicity

scientific article published on 01 April 1995

Coenzyme Q10 as a possible treatment for neurodegenerative diseases

scientific article

Coenzyme Q10 decreases amyloid pathology and improves behavior in a transgenic mouse model of Alzheimer's disease

scientific article published on January 2011

Coenzyme Q10 effects in neurodegenerative disease.

scientific article

Coenzyme Q10 in the central nervous system and its potential usefulness in the treatment of neurodegenerative diseases ⬇️

scientific article published on 01 January 1997

Combination therapy with coenzyme Q10 and creatine produces additive neuroprotective effects in models of Parkinson's and Huntington's diseases

scientific article

Commentary on "Alpha-synuclein and mitochondria: a tangled skein".

scientific article published in April 2004

Common threads in neurodegenerative disorders of aging

Concordant signaling pathways produced by pesticide exposure in mice correspond to pathways identified in human Parkinson's disease ⬇️

scientific article published on January 1, 2012

Conditional transgenic mice expressing C-terminally truncated human alpha-synuclein (alphaSyn119) exhibit reduced striatal dopamine without loss of nigrostriatal pathway dopaminergic neurons

scientific article published on 24 July 2009

Coordinate regulation of mature dopaminergic axon morphology by macroautophagy and the PTEN signaling pathway

scientific article

Cortical blindness and homonymous hemianopia in the postpartum period

scientific article published on 01 November 1980

Cortical cytochrome oxidase activity is reduced in Alzheimer's disease.

scientific article published in December 1994

Creatine and its potential therapeutic value for targeting cellular energy impairment in neurodegenerative diseases

scientific article

Creatine in Huntington disease is safe, tolerable, bioavailable in brain and reduces serum 8OH2'dG.

scientific article published in January 2006

Creatine increase survival and delays motor symptoms in a transgenic animal model of Huntington's disease

scientific article published in June 2001

Creatine therapy provides neuroprotection after onset of clinical symptoms in Huntington's disease transgenic mice

scientific article

Current and potential therapeutics in motor neuron diseases

Cytochemical Demonstration of Oxidative Damage in Alzheimer Disease by Immunochemical Enhancement of the Carbonyl Reaction with 2,4-Dinitrophenylhydrazine ⬇️

scientific article published on June 1, 1998

Cytochrome C and caspase-9 expression in Huntington's disease

scientific article

DJ-1 Cleavage by Matrix Metalloproteinase 3 Mediates Oxidative Stress-Induced Dopaminergic Cell Death ⬇️

scientific article published on March 10, 2011

Decreased striatal dopamine release underlies increased expression of long-term synaptic potentiation at corticostriatal synapses 24 h after 3-nitropropionic-acid-induced chemical hypoxia

scientific article published in September 2008

Detection of dopaminergic cell loss and neural transplantation using pharmacological MRI, PET and behavioral assessment.

scientific article published in September 1999

Detection of dopaminergic neurotransmitter activity using pharmacologic MRI: correlation with PET, microdialysis, and behavioral data.

scientific article published on September 1997

Determination of Coenzyme A and Acetyl-Coenzyme A in Biological Samples Using HPLC with UV Detection.

scientific article

Determination of neurotransmitter levels in models of Parkinson's disease by HPLC-ECD.

scientific article published in January 2011

Developmental changes in brain kynurenic acid concentrations.

scientific article published in July 1992

Dietary supplementation with resveratrol reduces plaque pathology in a transgenic model of Alzheimer's disease

scientific article

Diffusion tensor imaging in the diagnosis of primary lateral sclerosis

scientific article published on 01 January 2004

Distinct Nrf2 Signaling Mechanisms of Fumaric Acid Esters and Their Role in Neuroprotection against 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine-Induced Experimental Parkinson's-Like Disease

scientific article published on June 2016

Distribution of galanin-like immunoreactivity in baboon brain

scientific article published on 01 July 1988

Does impairment of energy metabolism result in excitotoxic neuronal death in neurodegenerative illnesses?

scientific article published on February 1, 1992

Does the mitochondrial genome play a role in the etiology of Alzheimer's disease?

scientific article published on 12 January 2006

Dopamine neurons derived from human ES cells efficiently engraft in animal models of Parkinson's disease

scientific article (publication date: 6 November 2011)

Dopaminergic neuronal loss, reduced neurite complexity and autophagic abnormalities in transgenic mice expressing G2019S mutant LRRK2.

scientific article published on 6 April 2011

Dysregulation of the levels of matrix metalloproteinases and tissue inhibitors of matrix metalloproteinases in the early phase of cerebral ischemia

scientific article

Effect of cysteamine on somatostatin and neuropeptide Y in rat striatum and cortical synaptosomes

scientific article published on 01 January 1987

Effects of CAG repeat length, HTT protein length and protein context on cerebral metabolism measured using magnetic resonance spectroscopy in transgenic mouse models of Huntington's disease

scientific article

Effects of Coenzyme Q10 in Huntington's disease and early Parkinson's disease

scientific article published on January 2003

Effects of coenzyme Q10 in early Parkinson disease: evidence of slowing of the functional decline

scientific article

Effects of lesions in the amygdala and periventricular hypothalamus on striatal somatostatin-like immunoreactivity

scientific article published in March 1985

Effects of lesions on somatostatin-like immunoreactivity in the rat striatum ⬇️

scientific article published on April 25, 1983

Elevated free nitrotyrosine levels, but not protein-bound nitrotyrosine or hydroxyl radicals, throughout amyotrophic lateral sclerosis (ALS)-like disease implicate tyrosine nitration as an aberrant in vivo property of one familial ALS-linked superox

scientific article published on July 1997

Elevated levels of matrix metalloproteinases-9 and -1 and of tissue inhibitors of MMPs, TIMP-1 and TIMP-2 in postmortem brain tissue of progressive supranuclear palsy

scientific article published in March 2004

Elevated “Hydroxyl Radical” Generation In Vivo in an Animal Model of Amyotrophic Lateral Sclerosis ⬇️

scientific article published on September 1, 1998

Elevation of neuronal MAO-B activity in a transgenic mouse model does not increase sensitivity to the neurotoxin 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)

scientific article published on 01 September 1994

Enhanced mitochondrial biogenesis ameliorates disease phenotype in a full-length mouse model of Huntington's disease

scientific article published on 22 March 2016

Estimation of hydroxyl free radical levels in vivo based on liquid chromatography with electrochemical detection

scientific article published on 01 January 1999

Evidence of oxidative stress in mdx mouse muscle: studies of the pre-necrotic state

scientific article published on 01 November 1998

Exaggerated inflammation, impaired host defense, and neuropathology in progranulin-deficient mice

scientific article

Excitotoxicity

scientific article published on 01 January 2007

Excitotoxicity and nitric oxide in parkinson's disease pathogenesis ⬇️

scientific article published on 01 September 1998

Excitotoxin lesions do not mimic the alteration of somatostatin in Huntington's disease

scientific article published in December 1985

Experimental therapeutics in transgenic mouse models of Huntington's disease

scientific article published on May 2004

Expression and activity of antioxidants in the brain in progressive supranuclear palsy

scientific article published in March 2002

Expression of MMP-2, MMP-9, and MMP-1 and their endogenous counterregulators TIMP-1 and TIMP-2 in postmortem brain tissue of Parkinson's disease

scientific article published in November 2002

Expression profiling of Huntington's disease models suggests that brain-derived neurotrophic factor depletion plays a major role in striatal degeneration

scientific article

Facilitation of postischemic reperfusion with alpha-PBN: assessment using NMR and Doppler flow techniques.

scientific article published on April 1997

Familial multisystem degeneration with parkinsonism associated with the 11778 mitochondrial DNA mutation

scientific article published on 01 November 1999

Frontal lobe dysfunction in progressive supranuclear palsy: evidence for oxidative stress and mitochondrial impairment

scientific article published on 01 February 2000

Functional engraftment of human ES cell-derived dopaminergic neurons enriched by coculture with telomerase-immortalized midbrain astrocytes.

scientific article published on 22 October 2006

Galanin-like immunoreactivity is unchanged in Alzheimer's disease and Parkinson's disease dementia cerebral cortex

scientific article (publication date: December 1988)

Genetic or pharmacological iron chelation prevents MPTP-induced neurotoxicity in vivo: a novel therapy for Parkinson's disease

scientific article published in March 2003

Genetically Decreased Spinal Cord Copper Concentration Prolongs Life in a Transgenic Mouse Model of Amyotrophic Lateral Sclerosis

article

Global ischemia induces NMDA receptor-mediated c-fos expression in neurons resistant to injury in gerbil hippocampus ⬇️

scientific article published on March 1, 1991

Glutamate toxicity in chronic neurodegenerative disease.

scientific article

HPLC determination of α-ketoglutaramate [5-amino-2,5-dioxopentanoate] in biological samples

scientific article published on 11 November 2015

Heterogeneous topographic and cellular distribution of huntingtin expression in the normal human neostriatum.

scientific article published in May 1997

High aggregate burden of somatic mtDNA point mutations in aging and Alzheimer's disease brain

scientific article

High-dose biotin restores redox balance, energy and lipid homeostasis, and axonal health in a model of adrenoleukodystrophy

scientific article published on 08 June 2020

Homocysteic acid lesions in rat striatum spare somatostatin—;Neuropeptide Y (NADPH-diaphorase) neurons ⬇️

scientific article published on 01 January 1990

Hugging tight in Huntington's

scientific article published in March 2011

Human cerebrospinal fluid somatostatin in neurologic disease

scientific article published on 01 November 1985

Hunting-ton for New Proteases: MMPs as the New Target? ⬇️

scientific article published on July 29, 2010

Huntington aggregates may not predict neuronal death in Huntington's disease

scientific article published in December 1999

Huntington's disease

scientific article published in January 2012

Huntington's disease and neurotoxins

scientific article published on May 11, 1992

Huntington's disease of the endocrine pancreas: insulin deficiency and diabetes mellitus due to impaired insulin gene expression

scientific article published in December 2002

Idiopathic cranial polyneuropathy. A fifteen-year experience

scientific article published on 01 February 1987

Immunoreactive somatostatin-28(1-12) is increased in Huntington's disease

scientific article published in May 1985

Immunosuppression and plasmapheresis in chronic progressive multiple sclerosis. Design of a clinical trial

scientific article published on 01 October 1983

Impaired PGC-1alpha function in muscle in Huntington's disease.

scientific article published on 21 May 2009

Impaired brain creatine kinase activity in Huntington's disease.

scientific article

Impaired brain energy metabolism in the BACHD mouse model of Huntington's disease: critical role of astrocyte-neuron interactions

scientific article

Impaired mitochondrial function in psychiatric disorders

scientific article published on 18 April 2012

Impairment of PGC-1alpha expression, neuropathology and hepatic steatosis in a transgenic mouse model of Huntington's disease following chronic energy deprivation

scientific article

Implanted fibroblasts genetically engineered to produce brain-derived neurotrophic factor prevent 1-methyl-4-phenylpyridinium toxicity to dopaminergic neurons in the rat.

scientific article

Improved therapeutic window for treatment of histotoxic hypoxia with a free radical spin trap

scientific article published on 01 November 1995

In vivo neurotoxicity of beta-amyloid [beta(1-40)] and the beta(25-35) fragment

scientific article published on September 1, 1992

Inactivation of Drosophila DJ-1 leads to impairments of oxidative stress response and phosphatidylinositol 3-kinase/Akt signaling

scientific article

Increased 3-nitrotyrosine and oxidative damage in mice with a human copper/zinc superoxide dismutase mutation.

scientific article published on September 1997

Increased 3-nitrotyrosine in brains of Apo E-deficient mice

scientific journal article

Increased Levels Of Plasma Cholesteryl Ester Hydroperoxides In Patients With Subarachnoid Hemorrhage ⬇️

scientific article published on 01 January 1997

Increased affinity for copper mediated by cysteine 111 in forms of mutant superoxide dismutase 1 linked to amyotrophic lateral sclerosis

article

Increased nitrotyrosine immunoreactivity in substantia nigra neurons in MPTP treated baboons is blocked by inhibition of neuronal nitric oxide synthase

scientific article published in March 1999

Increased oxidative damage to DNA in ALS patients

scientific article published on 01 October 2000

Increased oxidative damage to DNA in a transgenic mouse model of Huntington's disease

scientific article published in December 2001

Increased oxidative damage to DNA in an animal model of amyotrophic lateral sclerosis

scientific article published in April 2005

Increased plaque burden in brains of APP mutant MnSOD heterozygous knockout mice.

scientific article published in June 2004

Increased plasma levels of lipid hydroperoxides in patients with ischemic stroke

scientific article published in September 1998

Increased plasma levels of matrix metalloproteinase-9 in patients with Alzheimer's disease

scientific article published in August 2003

Increased survival and neuroprotective effects of BN82451 in a transgenic mouse model of Huntington's disease.

scientific article published in July 2003

Increased vulnerability to 3-nitropropionic acid in an animal model of Huntington's disease.

scientific article published in December 1998

Increases in cortical glutamate concentrations in transgenic amyotrophic lateral sclerosis mice are attenuated by creatine supplementation.

scientific article published in April 2001

Influence of mitochondrial enzyme deficiency on adult neurogenesis in mouse models of neurodegenerative diseases

scientific article

Inhibition of neuronal nitric oxide synthase by 7-nitroindazole protects against MPTP-induced neurotoxicity in mice.

scientific article published on February 1995

Inhibition of neuronal nitric oxide synthase prevents MPTP-induced parkinsonism in baboons

scientific article published in September 1996

Inhibition of neuronal nitric oxide synthase protects against MPTP toxicity

article

Inhibition of prolyl hydroxylase protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced neurotoxicity: model for the potential involvement of the hypoxia-inducible factor pathway in Parkinson disease

scientific article published on 13 August 2009

Inhibition of the leucine-rich repeat protein LINGO-1 enhances survival, structure, and function of dopaminergic neurons in Parkinson's disease models

scientific article

Inhibition of transglutaminase 2 mitigates transcriptional dysregulation in models of Huntington disease.

scientific article

Inosine to increase serum and cerebrospinal fluid urate in Parkinson disease: a randomized clinical trial

scientific article

Integrative role of cPLA with COX-2 and the effect of non-steriodal anti-inflammatory drugs in a transgenic mouse model of amyotrophic lateral sclerosis

scientific article published in April 2005

Intraneuronal Alzheimer abeta42 accumulates in multivesicular bodies and is associated with synaptic pathology

scientific article published on November 2002

Involvement of free radicals in excitotoxicity in vivo.

scientific article published in May 1995

Involvement of oxidative stress in 3-nitropropionic acid neurotoxicity

scientific article published on 01 August 1996

Iodoacetate produces striatal excitotoxic lesions.

scientific article published in July 1997

Iron porphyrin treatment extends survival in a transgenic animal model of amyotrophic lateral sclerosis

scientific article published in April 2003

Kynurenic acid concentrations are reduced in Huntington's disease cerebral cortex

scientific article (publication date: March 1992)

Lack of exacerbation of neurodegeneration in a double transgenic mouse model of mutant LRRK2 and tau.

scientific article published on 24 March 2015

Lack of involvement of neuronal nitric oxide synthase in the pathogenesis of a transgenic mouse model of familial amyotrophic lateral sclerosis

scientific article published in January 1999

Large stem cell grafts could lead to erroneous interpretations of behavioral results?

scientific article published on 01 February 2007

Lenalidomide (Revlimid) administration at symptom onset is neuroprotective in a mouse model of amyotrophic lateral sclerosis

scientific article

Less stress, longer life

scientific article published on 01 June 2005

Leucine-rich repeat kinase 2: a new player with a familiar theme for Parkinson's disease pathogenesis

scientific article

Limited-time exposure to mitochondrial toxins may lead to chronic progressive neurodegenerative diseases

scientific article published on 01 May 2000

Lipid peroxidation in aging brain and Alzheimer's disease

scientific article

Loss of Fas ligand-function improves survival in G93A-transgenic ALS mice

scientific article published on 17 October 2006

Lymphocyte oxidative DNA damage and plasma antioxidants in Alzheimer disease.

scientific article published in May 2002

MPTP and DSP-4 susceptibility of substantia nigra and locus coeruleus catecholaminergic neurons in mice is independent of parkin activity

scientific article

Malonate and 3-nitropropionic acid neurotoxicity are reduced in transgenic mice expressing a caspase-1 dominant-negative mutant.

scientific article published in August 2000

Malonate produces striatal lesions by indirect NMDA receptor activation

scientific article published in May 1994

Manganese intoxication in the rhesus monkey: a clinical, imaging, pathologic, and biochemical study

scientific article published on February 1996

Manganese porphyrin given at symptom onset markedly extends survival of ALS mice

scientific article published in August 2005

Manganese superoxide dismutase overexpression attenuates MPTP toxicity.

scientific article published in October 1998

Matrix metalloproteinase-3: a novel signaling proteinase from apoptotic neuronal cells that activates microglia.

scientific article

Matrix metalloproteinase-9 is elevated in 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced parkinsonism in mice

scientific article published in January 2004

Matrix metalloproteinase-9 regulates TNF-alpha and FasL expression in neuronal, glial cells and its absence extends life in a transgenic mouse model of amyotrophic lateral sclerosis

scientific article published on 12 February 2007

Measurement of kynurenic acid in mammalian brain extracts and cerebrospinal fluid by high-performance liquid chromatography with fluorometric and coulometric electrode array detection

scientific article (publication date: March 1990)

Measuring the effects of therapy in Parkinson disease

scientific article published on 01 May 2004

Mechanisms of excitotoxicity in neurologic diseases ⬇️

scientific article (publication date: December 1992)

Mechanisms of reduced striatal NMDA excitotoxicity in type I nitric oxide synthase knock-out mice

scientific article published in September 1997

Merging mitochondria for neuronal survival

scientific article published on 01 October 2007

Metabolomic analysis and signatures in motor neuron disease

scientific article published on January 2005

Metabolomic profiling in LRRK2-related Parkinson's disease

scientific article

Metabolomic profiling to develop blood biomarkers for Parkinson's disease

scientific article published in February 2008

Methylene blue upregulates Nrf2/ARE genes and prevents tau-related neurotoxicity

scientific article

Mice deficient in cellular glutathione peroxidase show increased vulnerability to malonate, 3-nitropropionic acid, and 1-methyl-4-phenyl-1,2,5,6-tetrahydropyridine

scientific journal article

Mice deficient in dihydrolipoamide dehydrogenase show increased vulnerability to MPTP, malonate and 3-nitropropionic acid neurotoxicity

scientific journal article

Mice deficient in dihydrolipoyl succinyl transferase show increased vulnerability to mitochondrial toxins

scientific article published on 4 August 2009

Mice deficient in group IV cytosolic phospholipase A2 are resistant to MPTP neurotoxicity.

scientific article published in December 1998

Mice lacking alpha-synuclein are resistant to mitochondrial toxins

scientific journal article

Mice overexpressing 70-kDa heat shock protein show increased resistance to malonate and 3-nitropropionic acid

scientific article published in July 2002

MicroRNA-related cofilin abnormality in Alzheimer's disease

scientific article

Minocycline enhances MPTP toxicity to dopaminergic neurons ⬇️

scientific article published on October 15, 2003

Mitochondria and Neurodegenerative Diseases

Mitochondria and antioxidant targeted therapeutic strategies for Alzheimer's disease

scientific article

Mitochondria and neurodegeneration

scientific article published on 01 January 2007

Mitochondria and oxidative stress in neurodegenerative disorders. Preface

scientific article published on 01 December 2008

Mitochondria and the pathogenesis of ALS

scientific article published on 01 July 2000

Mitochondria take center stage in aging and neurodegeneration

scientific article

Mitochondria targeted peptides protect against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity

scientific article

Mitochondria targeted therapeutic approaches in Parkinson's and Huntington's diseases ⬇️

scientific article published on 05 December 2012

Mitochondria, oxidative damage, and inflammation in Parkinson's disease

scientific article

Mitochondrial DNA 4977 bp deletion and OH8dG levels correlate in the brain of aged subjects but not Alzheimer's disease patients.

scientific article published in June 1999

Mitochondrial DNA and respiratory chain function in spinal cords of ALS patients

scientific article published in February 2002

Mitochondrial DNA from platelets of sporadic ALS patients restores normal respiratory functions in rho(0) cells

scientific article published in February 2003

Mitochondrial DNA mutations in complex I and tRNA genes in Parkinson's disease

scientific article published on 01 February 2000

Mitochondrial Dysfunction in Neurodegenerative Diseases ⬇️

scientific article published on June 13, 2012

Mitochondrial aconitase is a transglutaminase 2 substrate: transglutamination is a probable mechanism contributing to high-molecular-weight aggregates of aconitase and loss of aconitase activity in Huntington disease brain

scientific journal article

Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species.

scientific article published in September 2004

Mitochondrial approaches for neuroprotection

scientific article published on December 2008

Mitochondrial biology and oxidative stress in Parkinson disease pathogenesis

scientific article

Mitochondrial dihydrolipoyl succinyltransferase deficiency accelerates amyloid pathology and memory deficit in a transgenic mouse model of amyloid deposition

scientific article

Mitochondrial diseases of the brain.

scientific article published on 06 April 2013

Mitochondrial dysfunction and amyotrophic lateral sclerosis

scientific article

Mitochondrial dysfunction and oxidative damage in Alzheimer's and Parkinson's diseases and coenzyme Q10 as a potential treatment

scientific article published in August 2004

Mitochondrial dysfunction and oxidative stress in induced pluripotent stem cell models of Parkinson's disease

scientific article published on 01 December 2018

Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases

scientific article

Mitochondrial dysfunction in Parkinson's disease

scientific article published on 21 August 2016

Mitochondrial dysfunction in movement disorders.

scientific article

Mitochondrial dysfunction in neurodegenerative diseases

scientific article published on 01 August 1998

Mitochondrial dysfunction in progressive supranuclear palsy

scientific article

Mitochondrial dysfunction in the limelight of Parkinson's disease pathogenesis

scientific article

Mitochondrial loss, dysfunction and altered dynamics in Huntington's disease

scientific article

Mitochondrial membrane fluidity and oxidative damage to mitochondrial DNA in aged and AD human brain

scientific article published in May 1997

Mitochondrial pathology and muscle and dopaminergic neuron degeneration caused by inactivation of Drosophila Pink1 is rescued by Parkin

scientific article (publication date: 11 July 2006)

Mitochondrial permeability transition pore component cyclophilin D distinguishes nigrostriatal dopaminergic death paradigms in the MPTP mouse model of Parkinson's disease

scientific article published on 16 June 2011

Mitochondrial therapies for Parkinson's disease

scientific article published on January 2010

Molecular insights into Parkinson's disease ⬇️

scientific article

Motor neurons in Cu/Zn superoxide dismutase-deficient mice develop normally but exhibit enhanced cell death after axonal injury

scientific journal article

Movement disorder following excitotoxin lesions in primates

scientific article published on 01 June 1994

Multinuclear magnetic resonance spectroscopy for in vivo assessment of mitochondrial dysfunction in Parkinson's disease

scientific article

Muscling in on PGC-1α for improved quality of life in ALS ⬇️

scientific article published on 01 May 2012

Mutant LRRK2(R1441G) BAC transgenic mice recapitulate cardinal features of Parkinson's disease

scientific article

Mutant superoxide dismutase 1 forms aggregates in the brain mitochondrial matrix of amyotrophic lateral sclerosis mice.

scientific article published in March 2005

Mutated human SOD1 causes dysfunction of oxidative phosphorylation in mitochondria of transgenic mice

scientific article published on 5 June 2002

Mutations in mitochondrial cytochrome c oxidase genes segregate with late-onset Alzheimer disease

retracted scientific article

N-acetyl-L-cysteine improves survival and preserves motor performance in an animal model of familial amyotrophic lateral sclerosis

article

N-iminoethyl-L-lysine improves memory and reduces amyloid pathology in a transgenic mouse model of amyloid deposition

scientific article published on 13 November 2009

NADPH oxidase 1-mediated oxidative stress leads to dopamine neuron death in Parkinson's disease

scientific article

NGF, BDNF and NT-5, but not NT-3 protect against MPP+ toxicity and oxidative stress in neonatal animals

scientific article published in March 1996

NMDA antagonists partially protect against MPTP induced neurotoxicity in mice

scientific article published on 01 April 1993

NOS inhibitors decrease hypoxia-induced ATP reductions in respiring cerebrocortical slices

scientific article published on May 1999

Neural mitochondrial Ca2+ capacity impairment precedes the onset of motor symptoms in G93A Cu/Zn-superoxide dismutase mutant mice

scientific article published in March 2006

Neural subtype specification of fertilization and nuclear transfer embryonic stem cells and application in parkinsonian mice.

scientific article published on 21 September 2003

Neurochemical analysis of focal ischemia in rats ⬇️

scientific article published on 01 December 1991

Neurochemical and histologic characterization of striatal excitotoxic lesions produced by the mitochondrial toxin 3-nitropropionic acid

scientific article published on 01 October 1993

Neurochemical aspects of aging in primates

scientific article published on 01 November 1993

Neurochemical characteristics of aluminum-induced neurofibrillary degeneration in rabbits

scientific article published on 01 January 1989

Neurochemical characterization of excitotoxin lesions in the cerebral cortex ⬇️

scientific article published on January 1, 1991

Neurochemistry and toxin models in Huntington's disease.

scientific article published on December 1994

Neurodegenerative disease and the repair of oxidatively damaged DNA

Neuropeptide Y, somatostatin, and reduced nicotinamide adenine dinucleotide phosphate diaphorase in the human striatum: a combined immunocytochemical and enzyme histochemical study

scientific article published in March 1987

Neuroprotection by cyclodextrin in cell and mouse models of Alzheimer disease ⬇️

scientific article published on December 3, 2012

Neuroprotective and neurorestorative strategies for neuronal injury

scientific article published on 01 January 2000

Neuroprotective effect of Nrf2/ARE activators, CDDO ethylamide and CDDO trifluoroethylamide, in a mouse model of amyotrophic lateral sclerosis

scientific article

Neuroprotective effects of compounds with antioxidant and anti-inflammatory properties in a Drosophila model of Parkinson's disease

scientific article

Neuroprotective effects of creatine ⬇️

scientific article published on March 30, 2011

Neuroprotective effects of creatine administration against NMDA and malonate toxicity

scientific article published on 01 March 2000

Neuroprotective effects of creatine and cyclocreatine in animal models of Huntington's disease.

scientific article published in January 1998

Neuroprotective effects of creatine in a transgenic animal model of amyotrophic lateral sclerosis.

scientific article published in March 1999

Neuroprotective effects of creatine in a transgenic mouse model of Huntington's disease.

scientific article published in June 2000

Neuroprotective effects of free radical scavengers and energy repletion in animal models of neurodegenerative disease.

scientific article published on September 1995

Neuroprotective effects of oral administration of triacetyluridine against MPTP neurotoxicity

scientific article published in January 2004

Neuroprotective effects of phenylbutyrate against MPTP neurotoxicity.

scientific article published in January 2004

Neuroprotective effects of phenylbutyrate in the N171-82Q transgenic mouse model of Huntington's disease

scientific article published on 19 October 2004

Neuroprotective effects of synaptic modulation in Huntington's disease R6/2 mice.

scientific article

Neuroprotective effects of the triterpenoid, CDDO methyl amide, a potent inducer of Nrf2-mediated transcription.

scientific article

Neuroprotective mechanisms of creatine occur in the absence of mitochondrial creatine kinase

scientific article published in April 2004

Neuroprotective strategies for treatment of lesions produced by mitochondrial toxins: implications for neurodegenerative diseases

scientific article published on 01 April 1996

Neuroprotective strategies involving ROS in Alzheimer disease ⬇️

scientific article published on September 1, 2011

Neurotoxicity and behavioral deficits associated with Septin 5 accumulation in dopaminergic neurons

scientific article published on August 2005

Neurotransmitters in neocortex of aged rhesus monkeys ⬇️

scientific article published on September 1, 1991

Neurotrophic factors

New techniques for investigating mitochondrial DNA in neurodegenerative diseases ⬇️

scientific article published on 01 October 1997

Nitration of Hsp90 induces cell death

scientific article published on 4 March 2013

No evidence for preservation of somatostatin-containing neurons after intrastriatal injections of quinolinic acid

scientific article published in Nature

Non-invasive neurochemical analysis of focal excitotoxic lesions in models of neurodegenerative illness using spectroscopic imaging

scientific article published on May 1996

Nonlinear decrease over time in N-acetyl aspartate levels in the absence of neuronal loss and increases in glutamine and glucose in transgenic Huntington's disease mice.

scientific article published in May 2000

Novel therapies in the search for a cure for Huntington's disease

scientific article published in January 2001

Oral dyskinesias and histopathological alterations in substantia nigra after long-term haloperidol treatment of old rats

scientific article published on January 2003

Oral repeated-dose toxicity studies of coenzyme Q10 in beagle dogs

scientific article published on 20 January 2012

Oral uridine pro-drug PN401 is neuroprotective in the R6/2 and N171-82Q mouse models of Huntington's disease

scientific article published on 29 September 2006

Oxidative damage as an early marker of Alzheimer's disease and mild cognitive impairment

scientific article published in May 2005

Oxidative damage in Huntington's disease pathogenesis

scientific article published on November 2006

Oxidative damage to mitochondrial DNA is increased in Alzheimer's disease

scholarly article by Patrizia Mecocci et al published November 1994 in Annals of Neurology

Oxidative metabolism.

scientific article

Oxidative stress biomarkers in sporadic ALS

scientific article

Oxidative stress in Huntington's disease

scientific article published in January 1999

Oxidative stress in patients with Friedreich ataxia.

scientific article

Oxidative stress is attenuated in mice overexpressing BCL-2

scientific article published on 01 February 1999

Oxidatively modified proteins in aging and disease

scientific article

PGC-1alpha, a new therapeutic target in Huntington's disease?

scientific article published on November 2006

PGC-1α overexpression exacerbates β-amyloid and tau deposition in a transgenic mouse model of Alzheimer's disease

scientific article

PGC-1α, Sirtuins and PARPs in Huntington's Disease and Other Neurodegenerative Conditions: NAD+ to Rule Them All

scientific article published on 07 May 2019

PGC-1α, mitochondrial dysfunction, and Huntington's disease ⬇️

scientific article published on April 19, 2013

PINK1 defect causes mitochondrial dysfunction, proteasomal deficit and alpha-synuclein aggregation in cell culture models of Parkinson's disease

scientific article

PPAR: a therapeutic target in Parkinson's disease.

scientific article published on April 2008

Parkinson's disease

scientific article published on 02 October 2007

Parkinson's disease: a model dilemma

scientific article published in August 2010

Parkinsonism genes: culprits and clues

scientific article published on 6 July 2006

Partial deficiency of manganese superoxide dismutase exacerbates a transgenic mouse model of amyotrophic lateral sclerosis

article

Peroxisome proliferator-activated receptor-gamma agonist extends survival in transgenic mouse model of amyotrophic lateral sclerosis

scientific article published in February 2005

Pharmacologic activation of mitochondrial biogenesis exerts widespread beneficial effects in a transgenic mouse model of Huntington's disease ⬇️

scientific article published on November 17, 2011

Pilot trial of high dosages of coenzyme Q10 in patients with Parkinson's disease

scientific article

Pink1 regulates mitochondrial dynamics through interaction with the fission/fusion machinery

scholarly article

Pioglitazone halts axonal degeneration in a mouse model of X-linked adrenoleukodystrophy

scientific article

Poison and antidote: a novel model to study pathogenesis and therapy of LHON

scientific article published on 01 August 2004

Preferential PPAR-α activation reduces neuroinflammation, and blocks neurodegeneration in vivo

scientific article

Primary lateral sclerosis: a case report

scientific article published on 01 October 1981

Profiles of matrix metalloproteinases and their inhibitors in plasma of patients with dementia

scientific article published on 15 August 2007

Promethazine protects against 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine neurotoxicity.

scientific article published on 26 August 2005

Promethazine protects against 3-nitropropionic acid-induced neurotoxicity.

scientific article

Prophylactic creatine administration mediates neuroprotection in cerebral ischemia in mice

scientific article (publication date: 30 June 2004)

Prospects for neuroprotective therapies in prodromal Huntington's disease

scientific article published on 26 February 2014

Protection from Alzheimer's-like disease in the mouse by genetic ablation of inducible nitric oxide synthase

scientific article

Pulse inhibition of histone deacetylases induces complete resistance to oxidative death in cortical neurons without toxicity and reveals a role for cytoplasmic p21(waf1/cip1) in cell cycle-independent neuroprotection

scientific article published on January 2008

Reduced creatine kinase activity in transgenic amyotrophic lateral sclerosis mice

scientific article published in May 2002

Reduced-median-network analysis of complete mitochondrial DNA coding-region sequences for the major African, Asian, and European haplogroups

scientific article

Reduction of oxidative stress, amyloid deposition, and memory deficit by manganese superoxide dismutase overexpression in a transgenic mouse model of Alzheimer's disease

scientific article

Reduction of post-traumatic brain injury and free radical production by inhibition of the caspase-1 cascade

scientific article published on 01 January 1999

Reductions in the mitochondrial enzyme α-ketoglutarate dehydrogenase complex in neurodegenerative disease - beneficial or detrimental?

scientific article published on 31 August 2016

Regional somatostatin distribution in the rat striatum ⬇️

scientific article published on November 14, 1983

Remodeling chromatin and stress resistance in the central nervous system: histone deacetylase inhibitors as novel and broadly effective neuroprotective agents.

scientific article

Resveratrol protects against peripheral deficits in a mouse model of Huntington's disease

scientific article published in June 2010

Rewiring of Glutamine Metabolism Is a Bioenergetic Adaptation of Human Cells with Mitochondrial DNA Mutations

scientific article published on 12 April 2018

Role of Matrix Metalloproteinase 3-mediated α-Synuclein Cleavage in Dopaminergic Cell Death ⬇️

scientific article published on February 17, 2011

Safety and tolerability of high-dosage coenzyme Q10 in Huntington's disease and healthy subjects

scientific article

Sensitivity to oxidative stress in DJ-1-deficient dopamine neurons: an ES- derived cell model of primary Parkinsonism

scientific article

Sequence analysis of the entire mitochondrial genome in Parkinson's disease

scientific article published on 01 February 2002

Sex differences in cerebral energy metabolism in Parkinson's disease: A phosphorus magnetic resonance spectroscopic imaging study

scientific article published on 13 February 2014

Simultaneous determination of tricarboxylic acid cycle metabolites by high-performance liquid chromatography with ultraviolet detection

scientific article published on 18 March 2016

Somatic mitochondrial DNA mutations in cortex and substantia nigra in aging and Parkinson's disease

scientific article published on January 2004

Somatic mitochondrial DNA mutations in early parkinson and incidental lewy body disease ⬇️

scientific article published on June 1, 2012

Somatic mitochondrial DNA mutations in single neurons and glia

scientific article published on 29 December 2004

Somatostatin, neuropeptide Y, GABA and cholinergic enzymes in brain of pentylenetetrazol-kindled rats

scientific article published on 01 October 1989

Sparing of acetylcholinesterase-containing striatal neurons in Huntington's disease

scientific article published in May 1987

Stimulation of beta-amyloid precursor protein trafficking by insulin reduces intraneuronal beta-amyloid and requires mitogen-activated protein kinase signaling.

scientific article

Stress-induced mitochondrial depolarization and oxidative damage in PSP cybrids

scientific article published in September 2002

Striatal malonate lesions are attenuated in neuronal nitric oxide synthase knockout mice.

scientific article published in July 1996

Superoxide dismutase activity, oxidative damage, and mitochondrial energy metabolism in familial and sporadic amyotrophic lateral sclerosis

scientific article published on 01 December 1993

Superoxide dismutase concentration and activity in familial amyotrophic lateral sclerosis

scientific article published on 01 May 1995

Systemic approaches to modifying quinolinic acid striatal lesions in rats

scientific article published in October 1988

Targeting Nrf2-mediated gene transcription by extremely potent synthetic triterpenoids attenuate dopaminergic neurotoxicity in the MPTP mouse model of Parkinson's disease

scientific article published on 13 August 2012

Thalidomide and lenalidomide extend survival in a transgenic mouse model of amyotrophic lateral sclerosis.

scientific article published in March 2006

The alpha-ketoglutarate-dehydrogenase complex: a mediator between mitochondria and oxidative stress in neurodegeneration

scientific article

The cortical lesion of Huntington's disease: further neurochemical characterization, and reproduction of some of the histological and neurochemical features by N-methyl-D-aspartate lesions of rat cortex

scientific article published on October 1, 1992

The diagnostic utility of FLAIR imaging in clinically verified amyotrophic lateral sclerosis

scientific article published in May 2003

The effect of amphetamine on the in vivo release of dopamine, somatostatin and neuropeptide Y from rat caudate nucleus

scientific article published on 01 May 1987

The effect of peripheral loading with kynurenine and probenecid on extracellular striatal kynurenic acid concentrations

scientific article published in October 1992

The effect of somatostatin on striatal catecholamines ⬇️

scientific article published on February 24, 1984

The energetics of Huntington's disease

scientific article

The lipophilic metal chelators DP-109 and DP-460 are neuroprotective in a transgenic mouse model of amyotrophic lateral sclerosis

scientific article published on 01 August 2007

The matrix metalloproteinases inhibitor Ro 28-2653 [correction of Ro 26-2853] extends survival in transgenic ALS mice

scientific article published on 03 March 2006

The mitochondrial permeability transition as a target for neuroprotection

scientific article published in August 2004

The negative impact of α-ketoglutarate dehydrogenase complex deficiency on matrix substrate-level phosphorylation

scientific article published on 8 March 2013

The regional distribution of somatostatin and neuropeptide Y in control and Alzheimer's disease striatum

scientific article published in August 1987

The role of NADPH oxidase 1-derived reactive oxygen species in paraquat-mediated dopaminergic cell death

scientific article

The role of mitochondria in inherited neurodegenerative diseases

scientific article published on June 2006

The urokinase system of plasminogen activator plays a role in amyotrophic lateral sclerosis (ALS) pathogenesis

scientific article published on 14 March 2008

Therapeutic approaches to mitochondrial dysfunction in Parkinson's disease

scientific article

Therapeutic effects of coenzyme Q10 (CoQ10) and reduced CoQ10 in the MPTP model of Parkinsonism.

scientific article

Therapeutic effects of coenzyme Q10 and remacemide in transgenic mouse models of Huntington's disease.

scientific article

Therapeutic effects of coenzyme Q10 in neurodegenerative diseases

scientific article published on January 2004

Therapeutic effects of cystamine in a murine model of Huntington's disease.

scientific article published in October 2002

Therapeutic efficacy of EGb761 (Gingko biloba extract) in a transgenic mouse model of amyotrophic lateral sclerosis

scientific article published on 01 August 2001

Thiamine deficiency induces oxidative stress and exacerbates the plaque pathology in Alzheimer's mouse model

scientific article published on 10 April 2008

Toxin-induced mitochondrial dysfunction

scientific article

Transducer of regulated CREB-binding proteins (TORCs) transcription and function is impaired in Huntington's disease

scientific article

Transgenic ALS mice show increased vulnerability to the mitochondrial toxins MPTP and 3-nitropropionic acid.

scientific article published in April 2001

Treatment with a catalytic antioxidant corrects the neurobehavioral defect in ataxia-telangiectasia mice

scientific article published in April 2004

Triterpenoid CDDO-methylamide improves memory and decreases amyloid plaques in a transgenic mouse model of Alzheimer's disease

scientific article

Triterpenoids CDDO-ethyl amide and CDDO-trifluoroethyl amide improve the behavioral phenotype and brain pathology in a transgenic mouse model of Huntington's disease

scientific article

Truncated peroxisome proliferator-activated receptor-γ coactivator 1α splice variant is severely altered in Huntington's disease

scientific article

Uncoupling protein 2 prevents neuronal death including that occurring during seizures: a mechanism for preconditioning.

scientific article published on 21 August 2003

Unexpected lack of hypersensitivity in LRRK2 knock-out mice to MPTP (1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine).

scientific article

Urate as a predictor of the rate of clinical decline in Parkinson disease

scientific article

Urinary 8-hydroxy-2'-deoxyguanosine, a metabolite of oxidized DNA, is not elevated in HIV patients on combination antiretroviral therapy

scientific article

Usefulness of proton and phosphorus MR spectroscopic imaging for early diagnosis of Parkinson's disease.

scientific article published on 10 December 2013

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