Search filters

List of works by Gordon L. Hager

2-methoxyestradiol induces mammary gland differentiation through amphiregulin-epithelial growth factor receptor-mediated signaling: molecular distinctions from the mammary gland of pregnant mice

scientific article published on 7 December 2006

3D shortcuts to gene regulation

scientific article

A genome-wide map of CTCF multivalency redefines the CTCF code

scientific article published on 23 May 2013

A glucocorticoid/retinoic acid receptor chimera that displays cytoplasmic/nuclear translocation in response to retinoic acid. A real time sensing assay for nuclear receptor ligands

scientific article published on December 2001

A ligand binding domain mutation in the mouse glucocorticoid receptor functionally links chromatin remodeling and transcription initiation

scientific article

A novel in situ assay for the identification and characterization of soluble nuclear mobility factors

scientific article published on 22 June 2004

A novel transcriptional activator (PO-B) binds between the TATA box and cap site of the pro-opiomelanocortin gene

scientific article published in August 1990

ATP-dependent mobilization of the glucocorticoid receptor during chromatin remodeling

scientific article

Acetylation of Nucleosomal Histones by p300 Facilitates Transcriptionfrom Tax-Responsive Human T-Cell Leukemia Virus Type 1Chromatin Template.

scientific article

Acetylation of nucleosomal histones by p300 facilitates transcription from tax-responsive human T-cell leukemia virus type 1 chromatin template

scientific article

Actin-dependent intranuclear repositioning of an active gene locus in vivo.

scientific article

An estrogen receptor chimera senses ligands by nuclear translocation

scientific article published on 12 September 2005

Analysis of in vivo nucleosome positions by determination of nucleosome-linker boundaries in crosslinked chromatin

scientific article published on 01 February 1997

Analysis of nucleosome positioning in mammalian cells

scientific article published on 01 January 1999

Analysis of the peroxisome proliferator-activated receptor-β/δ (PPARβ/δ) cistrome reveals novel co-regulatory role of ATF4 ⬇️

scientific article published on November 24, 2012

Anti-Inflammatory Chromatinscape Suggests Alternative Mechanisms of Glucocorticoid Receptor Action

scientific article published on 4 August 2017

Are Assumptions about the Model Type Necessary in Reaction-Diffusion Modeling? A FRAP Application ⬇️

scientific article published on March 2, 2011

Binding of multiple factors to the MMTV promoter in crude and fractionated nuclear extracts

scientific article

Bivariate Genomic Footprinting Detects Changes in Transcription Factor Activity

scientific article published on May 2017

C/EBP maintains chromatin accessibility in liver and facilitates glucocorticoid receptor recruitment to steroid response elements ⬇️

scientific article published on May 10, 2013

Cajal bodies are linked to genome conformation

scientific article published on 21 March 2016

Cajal body function in genome organization and transcriptome diversity.

scientific article published on 21 October 2016

Characterization of BCE-1, a Transcriptional Enhancer Regulated by Prolactin and Extracellular Matrix and Modulated by the State of Histone Acetylation ⬇️

scientific article published on April 1, 1998

Characterization of an NF-1/CTF family member as a functional activator of the mouse mammary tumor virus long terminal repeat 5' enhancer

scientific article published in December 1996

Characterization of the human glucocorticoid receptor promoter

scientific article published on June 1995

Characterization of transiently and constitutively expressed progesterone receptors: evidence for two functional states

scientific article published on July 2000

Chromatin accessibility pre-determines glucocorticoid receptor binding patterns.

scientific article published on 23 January 2011

Chromatin dynamics and the evolution of alternate promoter states

scientific article

Chromatin in time and space ⬇️

scientific article published on 01 July 2012

Chromatin remodeling complexes interact dynamically with a glucocorticoid receptor-regulated promoter

scientific article published on 28 May 2008

Chromatin reprogramming in breast cancer

scientific article published on 24 April 2018

Chromatin structure and gene regulation: a dynamic view of enhancer function

scientific article published on 14 January 2016

Combinatorial probabilistic chromatin interactions produce transcriptional heterogeneity

scientific article published on 06 January 2009

Complex dynamics of transcription regulation ⬇️

scientific article published on March 28, 2012

Complex genomic interactions in the dynamic regulation of transcription by the glucocorticoid receptor ⬇️

scientific article published on March 14, 2013

Construction and Characterization of Molecular Clones Containing Integrated Mouse Mammary Tumor Virus Sequences ⬇️

scientific article published on January 1, 1980

Contribution of nucleosome binding preferences and co-occurring DNA sequences to transcription factor binding

scientific article

Control of nuclear receptor function by local chromatin structure.

scientific article published on 26 May 2011

Conventional and pioneer modes of glucocorticoid receptor interaction with enhancer chromatin in vivo.

scientific article published on 8 November 2017

Corticosterone pattern-dependent glucocorticoid receptor binding and transcriptional regulation within the liver

scientific article published on 10 August 2021

Covalent and noncovalent receptor-glucocorticoid complexes preferentially bind to the same regions of the long terminal repeat of murine mammary tumor virus proviral DNA.

scientific article published on December 1984

Cycles in spatial and temporal chromosomal organization driven by the circadian clock

scientific article published on 22 September 2013

DNA binding triggers tetramerization of the glucocorticoid receptor in live cells

scientific article published on 05 July 2016

DNA damage defines sites of recurrent chromosomal translocations in B lymphocytes

scientific article

DNA methylation status predicts cell type-specific enhancer activity.

scientific article

DNase footprint signatures are dictated by factor dynamics and DNA sequence

scientific article

Development of an image analysis screen for estrogen receptor alpha (ERα) ligands through measurement of nuclear translocation dynamics

scientific article

Development of assays for nuclear receptor modulators using fluorescently tagged proteins

scientific article published in January 2006

Differential activity of progesterone and glucocorticoid receptors on mouse mammary tumor virus templates differing in chromatin structure

scientific article published on May 1997

Differential in vivo binding dynamics of somatic and oocyte-specific linker histones in oocytes and during ES cell nuclear transfer

scientific article

Differential localization and activity of the A- and B-forms of the human progesterone receptor using green fluorescent protein chimeras

scientific article published on 01 March 1999

Differential steroid hormone induction of transcription from the mouse mammary tumor virus promoter.

scientific article published on May 1994

Direct visualization of the human estrogen receptor alpha reveals a role for ligand in the nuclear distribution of the receptor

scientific article

Distinctly different dynamics and kinetics of two steroid receptors at the same response elements in living cells

scientific article

Divergent Binding and Transactivation by Two Related Steroid Receptors at the Same Response Element.

scientific article published on 07 April 2016

Diverse gene reprogramming events occur in the same spatial clusters of distal regulatory elements

scientific article

Dual Roles for Ikaros in Regulation of Macrophage Chromatin State and Inflammatory Gene Expression

scientific article published on 13 June 2018

Dynamic access of the glucocorticoid receptor to response elements in chromatin.

scientific article

Dynamic behavior of transcription factors on a natural promoter in living cells

scientific article

Dynamic effect of bortezomib on nuclear factor-kappaB activity and gene expression in tumor cells.

scientific article

Dynamic enhancer function in the chromatin context.

scientific article

Dynamic exchange at regulatory elements during chromatin remodeling underlies assisted loading mechanism

scientific article

Dynamic interaction of HDAC1 with a glucocorticoid receptor-regulated gene is modulated by the activity state of the promoter

scientific article

Dynamic shuttling and intranuclear mobility of nuclear hormone receptors.

scientific article

Dynamics of chromatin accessibility and long-range interactions in response to glucocorticoid pulsing

scientific article

Dynamics of gene targeting and chromatin remodelling by nuclear receptors

scientific article published in January 2000

Dynamics of nuclear receptor movement and transcription

scientific article published on March 2004

Early Th1 cell differentiation is marked by a Tfh cell-like transition

scientific article published on December 2011

Epigenetic modulation of distal regulatory elements in oral squamous cell carcinoma (OSCC).

scientific article published on 19 August 2013

Epigenetic siRNA and Chemical Screens Identify SETD8 Inhibition as a Therapeutic Strategy for p53 Activation in High-Risk Neuroblastoma

scientific article

Evidence that nucleosomes on the mouse mammary tumor virus promoter adopt specific translational positions ⬇️

scientific article published on February 25, 1992

Expanding horizons for nuclear receptors.

scientific article

Extensive chromatin remodelling and establishment of transcription factor 'hotspots' during early adipogenesis.

scientific article

Fluorescence resonance energy transfer from cyan to yellow fluorescent protein detected by acceptor photobleaching using confocal microscopy and a single laser.

scientific article

Formation of higher-order secondary and tertiary chromatin structures by genomic mouse mammary tumor virus promoters

scientific article

Further Evidence for the Protein Coding Potential of the Mouse Mammary Tumor Virus Long Terminal Repeat: Nucleotide Sequence of an Endogenous Proviral Long Terminal Repeat ⬇️

scientific article published on March 1, 1983

Genome-Wide Chromatin Landscape Transitions Identify Novel Pathways in Early Commitment to Osteoblast Differentiation

scientific article published on 18 February 2016

Genome-Wide Identification of Basic Helix-Loop-Helix and NF-1 Motifs Underlying GR Binding Sites in Male Rat Hippocampus.

scientific article

Genome-wide binding potential and regulatory activity of the glucocorticoid receptor's monomeric and dimeric forms

scientific article published on 31 March 2021

Genome-wide footprinting: ready for prime time?

scientific article

Genome-wide mechanisms of nuclear receptor action

scientific article published on 30 September 2009

Global nature of dynamic protein-chromatin interactions in vivo: three-dimensional genome scanning and dynamic interaction networks of chromatin proteins

scientific article

Glucocorticoid Regulation of Transcription at an Amplified, Episomal Promoter ⬇️

scientific article published on November 1, 1983

Glucocorticoid receptor activation of the Ciz1-Lcn2 locus by long range interactions

scientific article published on 05 January 2009

Glucocorticoid receptor domain requirements for chromatin remodeling and transcriptional activation of the mouse mammary tumor virus promoter in different nucleoprotein contexts

scientific article

Glucocorticoid receptor dynamics and gene regulation

scientific article published on May 2009

Glucocorticoid receptor quaternary structure drives chromatin occupancy and transcriptional outcome

scientific article published on 23 July 2019

Glucocorticoid receptor-dependent disruption of a specific nucleosome on the mouse mammary tumor virus promoter is prevented by sodium butyrate

scientific article

Glucocorticoid regulation of the Ha-MuSV p21 gene conferred by sequences from mouse mammary tumor virus

scientific article published on December 1981

HDAC1 acetylation is linked to progressive modulation of steroid receptor-induced gene transcription

scientific article

High Quality ATAC-Seq Data Recovered from Cryopreserved Breast Cell Lines and Tissue

scientific article published in Scientific Reports

High fat diet-induced changes of mouse hepatic transcription and enhancer activity can be reversed by subsequent weight loss

scientific article published on 10 January 2017

High-content fluorescence-based screening for epigenetic modulators

scientific article published on January 2006

High-throughput RNA FISH analysis by imaging flow cytometry reveals that pioneer factor Foxa1 reduces transcriptional stochasticity

scientific article

High-throughput fluorescence-based screen to identify factors involved in nuclear receptor recruitment to response elements

scientific article published in January 2013

High-yield purification of functionally active glucocorticoid receptor

scientific article

Histone H1 phosphorylation is associated with transcription by RNA polymerases I and II

scientific article

Histone hyperacetylation does not alter the positioning or stability of phased nucleosomes on the mouse mammary tumor virus long terminal repeat ⬇️

scientific article published on April 9, 1991

Hormone-dependent, CARM1-directed, arginine-specific methylation of histone H3 on a steroid-regulated promoter ⬇️

scientific article published on December 11, 2001

Identification of compounds by high-content screening that induce cytoplasmic to nuclear localization of a fluorescent estrogen receptor α chimera and exhibit agonist or antagonist activity in vitro

scientific article

Identifying environmental chemicals as agonists of the androgen receptor by using a quantitative high-throughput screening platform

scientific article

Impact of chromatin structure on PR signaling: Transition from local to global analysis ⬇️

scientific article published on September 21, 2011

Independent actions on cyclin-dependent kinases and aryl hydrocarbon receptor mediate the antiproliferative effects of indirubins

scientific article published on May 2004

Independent glucocorticoid induction and repression of two contiguous responsive genes

scientific article published on July 1989

Influence of chromatin structure on the binding of transcription factors to DNA.

scientific article published on January 1993

Interaction of the glucocorticoid receptor with the chromatin landscape

scientific article

Interactome maps of mouse gene regulatory domains reveal basic principles of transcriptional regulation.

scientific article published on December 2013

Intracellular localization and trafficking of steroid receptors

scientific article

Intranuclear trafficking and gene targeting by members of the steroid/nuclear receptor superfamily ⬇️

scientific article published on April 1, 1998

Kinetic complexity of the global response to glucocorticoid receptor action.

scientific article published on 08 January 2009

Large-scale chromatin decondensation and recondensation regulated by transcription from a natural promoter

scientific article

Ligand-specific dynamics of the androgen receptor at its response element in living cells

scientific article

Ligand-specific dynamics of the progesterone receptor in living cells and during chromatin remodeling in vitro

scientific article

Limited Chemical Structural Diversity Found to Modulate Thyroid Hormone Receptor in the Tox21 Chemical Library

scientific article published on 30 September 2019

Live cell imaging unveils multiple domain requirements for in vivo dimerization of the glucocorticoid receptor

scientific article

Mechanism of FGF23 processing in fibrous dysplasia.

scientific article published on May 2012

Meta-analysis of Chromatin Programming by Steroid Receptors

scientific article published on 01 September 2019

Modulation of chromatin access during adipocyte differentiation

scientific article published in January 2012

Modulation of enhancer activity by the hormone responsive regulatory element from mouse mammary tumor virus ⬇️

scientific article published on August 1, 1984

Molecular architecture of transcription factor hotspots in early adipogenesis.

scientific article

Molecular chaperones function as steroid receptor nuclear mobility factors

scholarly article

Molecular cloning and characterization of STAMP1, a highly prostate-specific six transmembrane protein that is overexpressed in prostate cancer

scientific article

Molecular cloning and characterization of STAMP2, an androgen-regulated six transmembrane protein that is overexpressed in prostate cancer

scientific article

Molecular dynamics of ultradian glucocorticoid receptor action.

scientific article published on 22 August 2011

More than meets the dimer: What is the quaternary structure of the glucocorticoid receptor?

scientific article published on 20 October 2016

More to Hi-C than meets the eye ⬇️

scientific article published on October 27, 2011

Mouse mammary tumor virus chromatin in human breast cancer cells is constitutively hypersensitive and exhibits steroid hormone-independent loading of transcription factors in vivo

scientific article published on January 1995

Mouse model of endemic Burkitt translocations reveals the long-range boundaries of Ig-mediated oncogene deregulation

scientific article

Myc Regulates Chromatin Decompaction and Nuclear Architecture during B Cell Activation

scientific article published on 28 July 2017

New Face for Chromatin-Related Mesenchymal Modulator: n-CHD9 Localizes to Nucleoli and Interacts With Ribosomal Genes

scientific article published in September 2015

Newly expressed progesterone receptor cannot activate stable, replicated mouse mammary tumor virus templates but acquires transactivation potential upon continuous expression.

scientific article published on December 1993

Nonlinear dependencies of biochemical reactions for context-specific signaling dynamics.

scientific article

Novel cell-based assay for detection of thyroid receptor beta-interacting environmental contaminants

scientific article

Nuclear cytoplasmic shuttling by thyroid hormone receptors. multiple protein interactions are required for nuclear retention

scientific article

Nuclear pore protein NUP210 depletion suppresses metastasis through heterochromatin-mediated disruption of tumor cell mechanical response

scientific article published on 13 December 2021

Nucleoprotein structure influences the response of the mouse mammary tumor virus promoter to activation of the cyclic AMP signalling pathway

scientific article published on April 1995

Nucleosome positioning on the MMTV LTR results from the frequency-biased occupancy of multiple frames ⬇️

scientific article published on August 1, 1995

Nucleosomes reconstituted in vitro on mouse mammary tumor virus B region DNA occupy multiple translational and rotational frames

scientific article

OR26-6 Glucocorticoid Receptor Quaternary Structure Drives Chromatin Occupancy and Transcriptional Outcome.

scientific article

Overlapping chromatin-remodeling systems collaborate genome wide at dynamic chromatin transitions.

scientific article published on 08 December 2013

Phosphorylation of p53 at serine 37 is important for transcriptional activity and regulation in response to DNA damage

scientific article published on January 2004

Pilot study of global endocrine disrupting activity in Iowa public drinking water utilities using cell-based assays

scientific article published on 26 December 2019

Pioneer factors and ATP-dependent chromatin remodeling factors interact dynamically: A new perspective: Multiple transcription factors can effect chromatin pioneer functions through dynamic interactions with ATP-dependent chromatin remodeling factor

scientific article published on 16 September 2016

Prevalent glucocorticoid and androgen activity in US water sources

scientific article

Proopiomelanocortin Gene Promoter Elements Required for Constitutive and Glucocorticoid-Repressed Transcription ⬇️

scientific article published on December 1, 1991

Protein dynamics in the nuclear compartment

scientific article

Purification and stabilization of transcriptionally active glucocorticoid receptor

scientific article

Quantifying transcription factor binding dynamics at the single-molecule level in live cells

scientific article

Quantitative Analysis of Genome-Wide Chromatin Remodeling ⬇️

scientific article published on January 1, 2012

Rapid genome-scale mapping of chromatin accessibility in tissue

scientific article

Rapid glucocorticoid receptor exchange at a promoter is coupled to transcription and regulated by chaperones and proteasomes

scientific article published on April 2004

Rapid periodic binding and displacement of the glucocorticoid receptor during chromatin remodeling

scientific article

Recruitment of dioxin receptor to active transcription sites

scientific article

Regulatory and coding potential of the mouse mammary tumor virus long terminal redundancy ⬇️

scientific article published on January 1, 1981

Reprogramming the Chromatin Landscape: Interplay of the Estrogen and Glucocorticoid Receptors at the Genomic Level ⬇️

scientific article published on June 26, 2013

Retinoid-Induced Chromatin Structure Alterations in the Retinoic Acid Receptor β2 Promoter ⬇️

scientific article published on November 1, 1997

Role of the TATA box in transcription of the mouse mammary tumor virus long terminal repeat

scientific article published on September 1995

Selective intranuclear redistribution of PPAR isoforms by RXR alpha

scientific article published on April 2002

Sequence-specific DNA binding by glucocorticoid receptor "zinc finger peptides"

scientific article

Sequence-specific positioning of nucleosomes over the steroid-inducible MMTV promoter

scientific article

Simultaneous Visualization of the Yellow and Green Forms of the Green Fluorescent Protein in Living Cells ⬇️

scientific article published on September 1, 1998

Single-Cell Resolution and Quantitation of Targeted Glucocorticoid Delivery in the Thymus

scientific article published on 01 March 2019

Single-cell analysis of glucocorticoid receptor action reveals that stochastic post-chromatin association mechanisms regulate ligand-specific transcription

scientific article published on 27 July 2006

Single-molecule analysis of steroid receptor and cofactor action in living cells.

scientific article

Spatial congregation of STAT binding directs selective nuclear architecture during T-cell functional differentiation.

scientific article

Specific genomic cues regulate Cajal body assembly

scientific article published on 7 October 2016

Specific transcriptional initiation in vitro on murine type C retrovirus promoters ⬇️

scientific article published on July 1, 1981

Steroid Receptors Reprogram FoxA1 Occupancy through Dynamic Chromatin Transitions

scientific article

Steroid-dependent interaction of transcription factors with the inducible promoter of mouse mammary tumor virus in vivo

scientific article

Structural Modeling of GR Interactions with the SWI/SNF Chromatin Remodeling Complex and C/EBP

scientific article

Structure and dynamic properties of a glucocorticoid receptor-induced chromatin transition

scientific article

Subnuclear trafficking and gene targeting by steroid receptors

scientific article published in June 2004

Sustained oscillations of NF-kappaB produce distinct genome scanning and gene expression profiles

scientific article (publication date: 2009)

Switching of the relative dominance between feedback mechanisms in lipopolysaccharide-induced NF-κB signaling

scientific article published on 14 January 2014

Synergistic gene expression during the acute phase response is characterized by transcription factor assisted loading

scientific article published on 29 November 2017

Targeted H3R26 deimination specifically facilitates estrogen receptor binding by modifying nucleosome structure

scientific article

The 5' enhancer of the mouse mammary tumor virus long terminal repeat contains a functional AP-2 element.

scientific article published on December 1994

The HSP90 molecular chaperone cycle regulates cyclical transcriptional dynamics of the glucocorticoid receptor and its coregulatory molecules CBP/p300 during ultradian ligand treatment

scientific article

The Mouse Mammary Tumor Virus Model in Studies of Glucocorticoid Regulation

scientific article published on January 1, 1984

The Position and Length of the Steroid-Dependent Hypersensitive Region in the Mouse Mammary Tumor Virus Long Terminal Repeat Are Invariant despite Multiple Nucleosome B Frames ⬇️

scientific article published on June 1, 1998

The Three Ds of Transcription Activation by Glucagon: Direct, Delayed, and Dynamic.

scientific article

The glucocorticoid receptor associates with the cohesin loader NIPBL to promote long-range gene regulation

scientific article published on 30 March 2022

The glucocorticoid receptor interacting protein 1 (GRIP1) localizes in discrete nuclear foci that associate with ND10 bodies and are enriched in components of the 26S proteasome

scientific article

The glucocorticoid receptor is tethered to DNA-bound Oct-1 at the mouse gonadotropin-releasing hormone distal negative glucocorticoid response element

scientific article published on January 1999

The glucocorticoid receptor: rapid exchange with regulatory sites in living cells

scientific article

The ligand binding domain controls glucocorticoid receptor dynamics independent of ligand release.

scientific article published on 29 January 2007

The transcriptionally-active MMTV promoter is depleted of histone H1 ⬇️

scientific article published on January 25, 1992

The tumour suppressor and chromatin-remodelling factor BRG1 antagonizes Myc activity and promotes cell differentiation in human cancer

scientific article

Trafficking of nuclear receptors in living cells

scientific article

Trans-regulation of histone deacetylase activities through acetylation

scientific article published on 11 October 2009

Transcription Factor AP1 Potentiates Chromatin Accessibility and Glucocorticoid Receptor Binding ⬇️

scientific article published on July 8, 2011

Transcription dynamics

scientific article published on September 2009

Transcription factor access is mediated by accurately positioned nucleosomes on the mouse mammary tumor virus promoter.

scientific article published on February 1991

Transcription factor assisted loading and enhancer dynamics dictate the hepatic fasting response

scientific article published on 28 December 2016

Transcription factor loading on the MMTV promoter: a bimodal mechanism for promoter activation

scientific article

Transcriptional Bursting and Co-bursting Regulation by Steroid Hormone Release Pattern and Transcription Factor Mobility

scientific article published on 14 August 2019

Transcriptional activation by the thyroid hormone receptor through ligand-dependent receptor recruitment and chromatin remodelling.

scientific article published on 28 April 2015

Transcriptional and Chromatin Regulation during Fasting - The Genomic Era

scientific article

Transcriptional regulation of mammalian genes in vivo. A tale of two templates

scientific article

Transcriptional state of the mouse mammary tumor virus promoter can affect topological domain size in vivo

scientific article published on October 1999

Transient estrogen receptor binding and p300 redistribution support a squelching mechanism for estradiol-repressed genes

scientific article

Two regions of the mouse mammary tumor virus long terminal repeat regulate the activity of its promoter in mammary cell lines

scientific article published on May 1991

UV laser cross-linking: a real-time assay to study dynamic protein/DNA interactions during chromatin remodeling

scientific article published on 26 October 2004

Ultradian hormone stimulation induces glucocorticoid receptor-mediated pulses of gene transcription.

scientific article

Using inducible vectors to study intracellular trafficking of GFP-tagged steroid/nuclear receptors in living cells

scientific article

Visualization of glucocorticoid receptor translocation and intranuclear organization in living cells with a green fluorescent protein chimera

scientific article published on May 1996

Visualizing chromatin dynamics in intact cells.

scientific article

eRNAs promote transcription by establishing chromatin accessibility at defined genomic loci

scientific article published on 29 August 2013

p53 binding to nucleosomal DNA depends on the rotational positioning of DNA response element

scientific article

“Stripe” transcription factors provide accessibility to co-binding partners in mammalian genomes

scientific article published in 2022

Paulina is supported by:

About Paulina

Help