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List of works by Christopher J. Lelliott

A new role for lipocalin prostaglandin d synthase in the regulation of brown adipose tissue substrate utilization.

scientific article

Ablation of PGC-1beta results in defective mitochondrial activity, thermogenesis, hepatic function, and cardiac performance

scientific article (publication date: November 2006)

Accelerating functional gene discovery in osteoarthritis

scientific article published on 20 January 2021

Adaptive changes of the Insig1/SREBP1/SCD1 set point help adipose tissue to cope with increased storage demands of obesity

scientific article

Amelioration of lipid-induced insulin resistance in rat skeletal muscle by overexpression of Pgc-1β involves reductions in long-chain acyl-CoA levels and oxidative stress.

scientific article published on 18 February 2011

An Atlas of Human and Murine Genetic Influences on Osteoporosis

An Orphan CpG Island Drives Expression of a let-7 miRNA Precursor with an Important Role in Mouse Development

scientific article published on 13 March 2019

An atlas of genetic influences on osteoporosis in humans and mice

scientific article published on 31 December 2018

Author Correction: An atlas of genetic influences on osteoporosis in humans and mice

scientific article published on 01 May 2019

Characterization of the human, mouse and rat PGC1 beta (peroxisome-proliferator-activated receptor-gamma co-activator 1 beta) gene in vitro and in vivo

scientific article

Coordination of PGC-1beta and iron uptake in mitochondrial biogenesis and osteoclast activation

scientific journal article

Discovery of four recessive developmental disorders using probabilistic genotype and phenotype matching among 4,125 families

scientific article published on 5 October 2015

ETO/MTG8 is an inhibitor of C/EBPbeta activity and a regulator of early adipogenesis

scientific journal article

Hepatic PGC-1beta overexpression induces combined hyperlipidemia and modulates the response to PPARalpha activation.

scientific article published on 11 October 2007

High-fat feeding rapidly induces obesity and lipid derangements in C57BL/6N mice.

scientific article published on 28 May 2013

High-throughput discovery of genetic determinants of circadian misalignment

scientific article published on 13 January 2020

Human and mouse essentiality screens as a resource for disease gene discovery

scientific article published on 31 January 2020

Hypothalamic fatty acid metabolism mediates the orexigenic action of ghrelin.

scientific article published in May 2008

Identification of genetic elements in metabolism by high-throughput mouse phenotyping

scientific article published on 18 January 2018

In vivo imaging of lipid storage and regression in diet-induced obesity during nutrition manipulation

scientific article published on 02 October 2012

Intestinal, adipose, and liver inflammation in diet-induced obese mice.

scientific article published in December 2008

Lamin expression in human adipose cells in relation to anatomical site and differentiation state

scientific article published on February 2002

Large-scale neuroanatomical study uncovers 198 gene associations in mouse brain morphogenesis

scientific article published on 01 August 2019

Lipotoxicity, an imbalance between lipogenesis de novo and fatty acid oxidation

scientific article published on 01 December 2004

Loss of Mrap2 is associated with Sim1 deficiency and increased circulating cholesterol.

scientific article published on 22 April 2016

Lyplal1 is dispensable for normal fat deposition in mice

scientific article published on 26 October 2017

MacroH2A1 isoforms are associated with epigenetic markers for activation of lipogenic genes in fat-induced steatosis

scientific article

Metabolomic and Lipidomic Analysis of the Heart of Peroxisome Proliferator-Activated Receptor-γ Coactivator 1-β Knock Out Mice on a High Fat Diet

scientific article published on 18 June 2012

Mouse mutant phenotyping at scale reveals novel genes controlling bone mineral density

scientific article published on 28 December 2020

Mouse screen reveals multiple new genes underlying mouse and human hearing loss

article

Myosin 10 is involved in murine pigmentation.

scientific article published on 6 March 2018

Osteocyte transcriptome mapping identifies a molecular landscape controlling skeletal homeostasis and susceptibility to skeletal disease

scientific article published on 05 May 2021

PGC-1β Deficiency Accelerates the Transition to Heart Failure in Pressure Overload Hypertrophy ⬇️

scientific article published on July 28, 2011

Peroxisome proliferator-activated receptor gamma-coactivator-1 alpha coordinates sphingolipid metabolism, lipid raft composition and myelin protein synthesis.

scientific article

Prevalence of sexual dimorphism in mammalian phenotypic traits

scientific article

Regulation of adiponectin expression in human adipocytes: effects of adiposity, glucocorticoids, and tumor necrosis factor alpha.

scientific article

Sixteen diverse laboratory mouse reference genomes define strain-specific haplotypes and novel functional loci

scientific article published on 01 October 2018

Tamoxifen-induced anorexia is associated with fatty acid synthase inhibition in the ventromedial nucleus of the hypothalamus and accumulation of malonyl-CoA.

scientific article published in May 2006

Targeting of NAT10 enhances healthspan in a mouse model of human accelerated aging syndrome.

scientific article published on 27 April 2018

Targeting of Slc25a21 is associated with orofacial defects and otitis media due to disrupted expression of a neighbouring gene.

scientific article

The link between nutritional status and insulin sensitivity is dependent on the adipocyte-specific peroxisome proliferator-activated receptor-gamma2 isoform

scientific article

The role of sex and body weight on the metabolic effects of high-fat diet in C57BL/6N mice

scientific article

Transcript and metabolite analysis of the effects of tamoxifen in rat liver reveals inhibition of fatty acid synthesis in the presence of hepatic steatosis

scientific article published in July 2005

Trappc9 deficiency causes parent-of-origin dependent microcephaly and obesity

scientific article published on 02 September 2020

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