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List of works by Annika Scheffold

ATM-dependent phosphorylation of SNEVhPrp19/hPso4 is involved in extending cellular life span and suppression of apoptosis

scientific article published on April 2012

Anti-Leukemia Activity of the Selective BCL-2 Inhibitor ABT-199 in Childhood B-Cell Precursor Acute Lymphoblastic Leukemia Is Characterized By MCL-1/BCL-2 Expression Serving As Biomarker for Treatment Response ⬇️

scholarly article

Elevated Hedgehog activity contributes to attenuated DNA damage responses in aged hematopoietic cells

scientific article published on 14 November 2019

Functional characterization of BRCC3 mutations in acute myeloid leukemia with t(8;21)(q22;q22.1)

scientific article published on 01 October 2019

Generation of a lenalidomide-sensitive syngeneic murine in vivo multiple myeloma model by expression of CrbnI391V

scientific article published on 10 November 2020

IGF1R as druggable target mediating PI3K-δ inhibitor resistance in a murine model of chronic lymphocytic leukemia

scientific article published on 22 April 2019

Impact of telomere length on the outcome of allogeneic stem cell transplantation for poor-risk chronic lymphocytic leukaemia: results from the GCLLSG CLL3X trial

scientific article published on 8 July 2016

Mutual exacerbation of peroxisome proliferator-activated receptor γ coactivator 1α deregulation and α-synuclein oligomerization

scientific article

Oxidative stress as candidate therapeutic target to overcome microenvironmental protection of CLL

scientific article published on 12 July 2019

PI3Kδ inhibition modulates regulatory and effector T-cell differentiation and function in chronic lymphocytic leukemia

scientific article published on 20 December 2018

Prediction of venetoclax activity in precursor B-ALL by functional assessment of apoptosis signaling

scientific article published on 29 July 2019

Reconstruction of rearranged T-cell receptor loci by whole genome and transcriptome sequencing gives insights into the initial steps of T-cell prolymphocytic leukemia

scientific article published on 29 November 2019

Revolution of Chronic Lymphocytic Leukemia Therapy: the Chemo-Free Treatment Paradigm

scientific article published on 05 February 2020

Short telomeres are associated with inferior outcome, genomic complexity, and clonal evolution in chronic lymphocytic leukemia

scientific article published on 25 March 2019

Substantial telomere shortening in the substantia nigra of telomerase-deficient mice does not increase susceptibility to MPTP-induced dopamine depletion

scientific article published in March 2014

TBET-expressing Th1 CD4+ T cells accumulate in chronic lymphocytic leukaemia without affecting disease progression in Eµ-TCL1 mice

scientific article published on 14 November 2019

Telomerase gene mutations are associated with cirrhosis formation

scientific article published in May 2011

Telomere Lenght and Outcome of Allogeneic Stem Cell Transplantation for Poor Risk Chronic Lymphocytic Leukemia: Results from the GCLLSG CLL3X Trial ⬇️

scholarly article

Telomere length in poor-risk chronic lymphocytic leukemia: associations with disease characteristics and outcome

scientific article published on 24 October 2017

Telomere shortening leads to an acceleration of synucleinopathy and impaired microglia response in a genetic mouse model

scientific article published on 22 August 2016

Telomere shortening leads to earlier age of onset in ALS mice

scientific article published on February 2016

Telomere shortening reduces Alzheimer's disease amyloid pathology in mice

scientific article published on 14 June 2011

Thirty-eight-negative kinase 1 mediates trauma-induced intestinal injury and multi-organ failure

Transient telomere dysfunction induces chromosomal instability and promotes carcinogenesis

scientific article published on 01 January 2021

Transient telomere dysfunction induces chromosomal instability and promotes carcinogenesis.

scientific article

Vecabrutinib Is Efficacious In Vivo in a Preclinical CLL Adoptive Transfer Model ⬇️

scholarly article

Venetoclax: Targeting BCL2 in Hematological Cancers

scientific article published on 01 January 2018

Whole-Exome Sequencing Revealed No Recurrent Mutations within the PI3K Pathway in Relapsed Chronic Lymphocytic Leukemia Patients Progressing Under Idelalisib Treatment ⬇️

scholarly article

YAP Activation Drives Liver Regeneration after Cholestatic Damage Induced by Deletion

article published in 2018

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