List of works - Massimo Tabaton

17A, a novel non-coding RNA, regulates GABA B alternative splicing and signaling in response to inflammatory stimuli and in Alzheimer disease

scientific article published on October 2010

A novel origin for granulovacuolar degeneration in aging and Alzheimer's disease: parallels to stress granules

scientific article

A novel presenilin 1 L166H mutation in a pseudo-sporadic case of early-onset Alzheimer's disease

scientific article published in December 2005

A quantitative and ultrastructural study of substantia nigra and nucleus centralis superior in Alzheimer's disease

scientific article published in January 1985

A silver lining for 24-hydroxycholesterol in Alzheimer's disease: The involvement of the neuroprotective enzyme sirtuin 1.

scientific article

AGEs/RAGE complex upregulates BACE1 via NF-κB pathway activation

scientific article published on 17 July 2010

Abnormal tau-reactive filaments in olfactory mucosa in biopsy specimens of patients with probable Alzheimer's disease

scientific article published in March 1991

Adjunctive agomelatine therapy in the treatment of acute bipolar II depression: a preliminary open label study

scientific article

Alternative, non-secretase processing of Alzheimer's beta-amyloid precursor protein during apoptosis by caspase-6 and -8.

scientific article published in July 1999

Alz 50 recognizes abnormal filaments in Alzheimer's disease and progressive supranuclear palsy

scientific article published in September 1988

Amnestic mild cognitive impairment and conversion to Alzheimer's disease: insulin resistance and glycoxidation as early biomarker clusters.

scientific article published in January 2015

Amyloid beta protein deposition in brains from elderly subjects with leukoaraiosis

scientific article published in December 1991

Amyloid precursor protein in cell cultures: a 130 kDa polypeptide

scientific article published in January 1989

Amyloid-beta deposition in Alzheimer transgenic mice is associated with oxidative stress

scientific article published in May 1998

Amyloid-beta42 plasma levels are elevated in amnestic mild cognitive impairment

scientific article published in January 2009

Amyloid-β Deposition in Alzheimer Transgenic Mice Is Associated with Oxidative Stress

article published in 2002

Amyloid-β Production: Major Link Between Oxidative Stress and BACE1 ⬇️

scientific article published on October 15, 2011

Amyloid-β₄₂ activates the expression of BACE1 through the JNK pathway

scientific article

Apolipoprotein E element 4 allele frequency is not increased in progressive supranuclear palsy ⬇️

scientific article published on 01 September 1995

Artificial neural networks identify the predictive values of risk factors on the conversion of amnestic mild cognitive impairment

scientific article published in January 2010

Association of a presenilin 1 S170F mutation with a novel Alzheimer disease molecular phenotype

scientific article

Autophagocytosis of mitochondria is prominent in Alzheimer disease

scientific article

Autophagocytosis of mitochondria is prominent in Alzheimer disease

Aβ1-42 monomers or oligomers have different effects on autophagy and apoptosis

scientific article

Aβ1-42-mediated down-regulation of Uch-L1 is dependent on NF-κB activation and impaired BACE1 lysosomal degradation

scientific article

Beta protein immunoreactivity is found in the majority of neurofibrillary tangles of Alzheimer's disease ⬇️

scientific article published on February 1, 1992

Beta-amyloid 1-42 monomers, but not oligomers, produce PHF-like conformation of Tau protein

scientific article published on 12 July 2016

Beta-site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stress-activated protein kinases pathways.

scientific article published on February 2005

Birth of JAD: 20 Years Later.

scientific article published in January 2018

CD36 overexpression in human brain correlates with beta-amyloid deposition but not with Alzheimer's disease

scientific article published in April 2004

Cerebrospinal fluid and neuropathological study in Devic's syndrome. Evidence of intrathecal immune activation

scientific article

Chronic oxidative stress causes increased tau phosphorylation in M17 neuroblastoma cells

scientific article

Complete bilateral relapsing ophthalmoplegia in a diabetic patient with a sensory-motor distal polyneuropathy

scientific article published on 01 January 1986

Creutzfeldt-Jakob disease in the city and district of Genoa: estimated mortality rate in the six year period 1974-1979

scientific article published on 01 May 1981

Demonstration of a novel neurofilament associated antigen with the neurofibrillary pathology of Alzheimer and related diseases

scientific article published in August 1991

Direct immunofluorescence in sural nerve biopsies

scientific article published on 01 January 1988

Dissociated amyloid-beta antibody levels as a serum biomarker for the progression of Alzheimer's disease: a population-based study

scientific article

Dual Mechanism of Toxicity for Extracellular Injection of Tau Oligomers versus Monomers in Human Tau Mice

scientific article

Dystrophic neurites infiltrate extracellular neurofibrillary tangles in Alzheimer disease

scientific article published in September 1991

Early contribution of oxidative glycation in Alzheimer disease

scientific article published on 01 October 1996

Early glycoxidation damage in brains from Down's syndrome.

scientific article

Elevation of {beta}-amyloid 1-42 autoantibodies in the blood of amnestic patients with mild cognitive impairment

scientific article published in July 2010

Endogenous APP derivatives oppositely modulate apoptosis through an autocrine loop

scientific article published on 01 May 2000

Estrogens Inhibit Amyloid-β-Mediated Paired Helical Filament-Like Conformation of Tau Through Antioxidant Activity and miRNA 218 Regulation in hTau Mice

scientific article published on 11 August 2020

Evidence that the Amyloid beta Precursor Protein-intracellular domain lowers the stress threshold of neurons and has a "regulated" transcriptional role

scientific article published on 2 September 2008

Familial progressive subcortical gliosis: presence of prions and linkage to chromosome 17

scientific article published on 01 June 1995

Fibroblasts from FAD-linked presenilin 1 mutations display a normal unfolded protein response but overproduce Abeta42 in response to tunicamycin

scientific article published in March 2004

Formic acid treatment exposes hidden neurofilament and tau epitopes in abnormal cytoskeletal filaments from patients with progressive supranuclear palsy and Alzheimer's disease

scientific article published in July 1990

Frontal Variant of Alzheimer's Disease: A Report of a Novel PSEN1 Mutation

scientific article published on 01 January 2019

Frontotemporal dementia and corticobasal degeneration in a family with a P301S mutation in tau.

scientific article

GFAP expression of human Schwann cells in tissue culture

scientific article published in January 1992

Generalized chorea due to bilateral small, deep cerebral infarcts

scientific article published on 01 April 1985

Generation of an apoptotic intracellular peptide by gamma-secretase cleavage of Alzheimer's amyloid beta protein precursor.

scientific article published in November 2000

HLA-DR Schwann cell reactivity in peripheral neuropathies of different origins

scientific article published on 01 June 1988

Hereditary motor and sensory neuropathy with deafness, mental retardation and absence of large myelinated fibers.

scientific article published on July 1992

Heterogeneity of water‐soluble amyloid β‐peptide in Alzheimer's disease and Down's syndrome brains ⬇️

scientific article published on June 16, 1997

Increase of cdk5 is related to neurofibrillary pathology in progressive supranuclear palsy

scientific article

Increased amyloidogenic secretion in cerebellar granule cells undergoing apoptosis

scientific article published on February 1998

Increased autophagic degradation of mitochondria in Alzheimer disease

scientific article published on 14 August 2007

Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment

scientific article

Increased oxidative stress involving olfactory neurons in Alzheimer disease

Influence of neuronal location on antigenic properties of neurofibrillary tangles ⬇️

scientific article published on 01 June 1988

Is amyloid beta-protein glycated in Alzheimer's disease?

scientific article

Italian multicenter study of dementia: a pathologically verified case of Alzheimer disease

scientific article published in February 1986

JNK and ERK1/2 pathways have a dual opposite effect on the expression of BACE1.

scientific article published on 6 February 2008

La función del estrés oxidativo en la patogénesis de la enfermedad de Alzheimer

Lipoperoxidation is selectively involved in progressive supranuclear palsy

scientific article published on 01 May 2000

Locked-in syndrome in acute inflammatory polyradiculoneuropathy

scientific article published on 01 January 1984

Mechanisms of phenotypic heterogeneity in prion, Alzheimer and other conformational diseases

scientific article published on 01 February 2001

Memantine: "hypothesis testing" not "disease modifying" in Alzheimer's disease

scientific article

Microarray analysis in Alzheimer's disease and normal aging

scientific article published on 01 June 2004

Microtubule Reduction in Alzheimer's Disease and Aging Is Independent of τ Filament Formation ⬇️

scientific article published on May 1, 2003

Mitochondrial abnormalities in Alzheimer's disease.

scientific article published in May 2001

Monoclonal IgM-associated demyelinating peripheral neuropathy: an expression of monoclonal autoimmunity

scientific article published on 01 November 1985

Monomeric Aβ1-42 and RAGE: key players in neuronal differentiation.

scientific article published on 10 January 2014

Multiple signaling events in amyloid beta-induced, oxidative stress-dependent neuronal apoptosis

scientific article

Mutant presenilin 1 increases the expression and activity of BACE1

scientific article published on 05 February 2009

N-terminal truncated pyroglutamyl beta amyloid peptide Abetapy3-42 shows a faster aggregation kinetics than the full-length Abeta1-42.

scientific article published in October 2009

Neprylisin decreases uniformly in Alzheimer's disease and in normal aging

scientific article

Neurochemistry of dementia: establishing the links

scientific article

Neuronal apoptosis is accompanied by amyloid beta-protein accumulation in the endoplasmic reticulum.

scientific article published on February 2002

Neuropil threads of Alzheimer's disease show a marked alteration of the normal cytoskeleton

scientific article published in June 1991

Neuroprotective properties of Bcl-w in Alzheimer disease

scientific article

Nontraumatic dissecting aneurysm of the basilar artery

scientific article published on 01 January 1983

Office of Rare Diseases neuropathologic criteria for corticobasal degeneration.

scientific article published in November 2002

Opposite roles of apolipoprotein E in normal brains and in Alzheimer's disease.

scientific article

Oxidative damage in the olfactory system in Alzheimer's disease

scientific article

Oxidative stress activates a positive feedback between the gamma- and beta-secretase cleavages of the beta-amyloid precursor protein ⬇️

scientific article

Oxidative stress and neuronal adaptation in Alzheimer disease: the role of SAPK pathways

scientific article published on October 2003

Oxidative stress in Alzheimer disease: a possibility for prevention

scientific article published on 13 April 2010

Oxidative stress increases expression and activity of BACE in NT2 neurons

scientific article published in August 2002

Oxidative stress induces increase in intracellular amyloid beta-protein production and selective activation of betaI and betaII PKCs in NT2 cells

article

Oxidative stress mediates the pathogenic effect of different Alzheimer's disease risk factors

scientific article published on 9 February 2010

P1-286 Glycogen synthase kinase-3β activity is regulated by products of lipid peroxidation: relevance to Alzheimer disease

Paraffin-embedded tissue (PET) blot method: application to Alzheimer disease

scientific article

Peripheral neuropathy in Cockayne syndrome

scientific article published on 01 August 1986

Plasma levels of amyloid beta 40 and 42 are independent from ApoE genotype and mental retardation in Down syndrome

scientific article published in November 2000

Plasma levels of amyloid beta-protein 42 are increased in women with mild cognitive impairment.

scientific article published in September 2004

Plasma levels of insulin and amyloid beta 42 are correlated in patients with amnestic Mild Cognitive Impairment

scientific article

Polyglucosan bodies in the sural nerve of a diabetic patient with polyneuropathy

scientific article published on 01 January 1985

Position paper of the Italian Society for the study of Dementias (SINDEM) on the proposal of a new lexicon on Alzheimer disease

scientific article

Preface

Preliminary NINDS neuropathologic criteria for Steele-Richardson-Olszewski syndrome (progressive supranuclear palsy).

scientific article published on November 1994

Presence of soluble amyloid beta-peptide precedes amyloid plaque formation in Down's syndrome

scientific article published on 01 January 1996

Prion deposition in olfactory biopsy of sporadic Creutzfeldt-Jakob disease

scientific article published on 01 February 2004

Protein levels of glycogen synthase 3 kinase are normal in progressive supranuclear palsy

scientific article published on 01 August 2004

Pure spastic paraparesis associated with a novel presenilin 1 R278K mutation

scientific article published in January 2003

RNA polymerase III drives alternative splicing of the potassium channel-interacting protein contributing to brain complexity and neurodegeneration

scientific article

Regulation of glycogen synthase kinase-3beta by products of lipid peroxidation in human neuroblastoma cells

scientific article published on June 2004

Role of water-soluble amyloid-beta in the pathogenesis of Alzheimer's disease

scientific article

Schwann cell GFAP expression increases in axonal neuropathies

scientific article published on 01 April 1991

Selective presence of ubiquitin in intracellular inclusions

scientific article

Senile plaques in cerebral amyloid angiopathy show accumulation of amyloid precursor protein without cytoskeletal abnormalities ⬇️

scientific article published on October 16, 1992

Signaling effect of amyloid-beta(42) on the processing of AbetaPP

scientific article

Soluble amyloid beta-protein is increased in frontotemporal dementia with tau gene mutations.

scientific article published in February 2004

Soluble amyloid-beta in the brain: the scarlet pimpernel

scientific article published on January 2006

Subcellular localization of amyloid precursor protein in senile plaques of Alzheimer's disease ⬇️

scientific article published on April 1, 1992

Survival rate in patients affected by dementia followed by memory clinics (UVA) in Italy.

scientific article published in January 2013

Tau gene mutation in familial progressive subcortical gliosis

scientific article published in April 1999

Tau-reactive neurofibrillary tangles in cerebellar cortex from patients with Alzheimer's disease

scientific article

The 14-3-3 protein in multiple sclerosis: a marker of disease severity

scientific article published on 01 October 2004

The H1 haplotype of the tau gene (MAPT) is associated with mild cognitive impairment.

scientific article published in January 2010

The Unexpected Role of Aβ1-42 Monomers in the Pathogenesis of Alzheimer's Disease

scientific article published on 30 October 2017

The cell cycle regulator phosphorylated retinoblastoma protein is associated with tau pathology in several tauopathies

scientific article

The concept of redox balance in Alzheimer's disease: Mark Anthony Smith 1965–2010

scholarly article by Xiongwei Zhu et al published March 2011 in Redox Report

The earliest stage of cognitive impairment in transition from normal aging to Alzheimer disease is marked by prominent RNA oxidation in vulnerable neurons

scientific article published on March 2012

The increased activity of BACE1 correlates with oxidative stress in Alzheimer's disease

scientific article published in July 2007

The up-regulation of BACE1 mediated by hypoxia and ischemic injury: role of oxidative stress and HIF1alpha

scientific article

The various aggregation states of beta-amyloid 1-42 mediate different effects on oxidative stress, neurodegeneration, and BACE-1 expression

scientific article published on 14 February 2006

The widespread alteration of neurites in Alzheimer's disease may be unrelated to amyloid deposition

scientific article published on December 1989

Tyrosine kinase A-nerve growth factor receptor is antigenically present in dystrophic neurites from a variety of conditions but not in Alzheimer's disease.

scientific article

Ubiquitin is associated with abnormal cytoplasmic filaments characteristic of neurodegenerative diseases

scientific article

Ubiquitin-reactive axons have a widespread distribution and are unrelated to prion protein plaques in Creutzfeldt-Jakob disease

scientific article published in July 1992

Ubiquitin-reactive neurites in cerebral cortex of subjects with Huntington's chorea: a pathological correlate of dementia?

scientific article published in June 1993

Ultrastructural localization of beta-amyloid, tau, and ubiquitin epitopes in extracellular neurofibrillary tangles ⬇️

scientific article published on March 15, 1991

Upregulation of presenilin 1 in brains of sporadic, late-onset Alzheimer's disease

scientific article published in January 2010

Validity and reliability of the preliminary NINDS neuropathologic criteria for progressive supranuclear palsy and related disorders.

scientific article published on January 1996

What can artificial neural networks teach us about neurodegenerative disorders with extrapyramidal features?

scientific article published on June 1996

Zoster sine herpete causing encephalomyelitis

scientific article published on 01 February 1987

beta-amyloid is different in normal aging and in Alzheimer disease.

scientific article published on 15 August 2005

α-Synuclein RT-QuIC assay in cerebrospinal fluid of patients with dementia with Lewy bodies

scientific article published on 10 October 2019

β-amyloid 1-42 induces physiological transcriptional regulation of BACE1.

scientific article

List of works by Massimo Tabaton

17A, a novel non-coding RNA, regulates GABA B alternative splicing and signaling in response to inflammatory stimuli and in Alzheimer disease

A novel origin for granulovacuolar degeneration in aging and Alzheimer's disease: parallels to stress granules

A novel presenilin 1 L166H mutation in a pseudo-sporadic case of early-onset Alzheimer's disease

A quantitative and ultrastructural study of substantia nigra and nucleus centralis superior in Alzheimer's disease

A silver lining for 24-hydroxycholesterol in Alzheimer's disease: The involvement of the neuroprotective enzyme sirtuin 1.

AGEs/RAGE complex upregulates BACE1 via NF-κB pathway activation

Abnormal tau-reactive filaments in olfactory mucosa in biopsy specimens of patients with probable Alzheimer's disease

Adjunctive agomelatine therapy in the treatment of acute bipolar II depression: a preliminary open label study

Alternative, non-secretase processing of Alzheimer's beta-amyloid precursor protein during apoptosis by caspase-6 and -8.

Alz 50 recognizes abnormal filaments in Alzheimer's disease and progressive supranuclear palsy

Amnestic mild cognitive impairment and conversion to Alzheimer's disease: insulin resistance and glycoxidation as early biomarker clusters.

Amyloid beta protein deposition in brains from elderly subjects with leukoaraiosis

Amyloid precursor protein in cell cultures: a 130 kDa polypeptide

Amyloid-beta deposition in Alzheimer transgenic mice is associated with oxidative stress

Amyloid-beta42 plasma levels are elevated in amnestic mild cognitive impairment

Amyloid-β Deposition in Alzheimer Transgenic Mice Is Associated with Oxidative Stress

Amyloid-β Production: Major Link Between Oxidative Stress and BACE1 ⬇️

Amyloid-β₄₂ activates the expression of BACE1 through the JNK pathway

Apolipoprotein E element 4 allele frequency is not increased in progressive supranuclear palsy ⬇️

Artificial neural networks identify the predictive values of risk factors on the conversion of amnestic mild cognitive impairment

Association of a presenilin 1 S170F mutation with a novel Alzheimer disease molecular phenotype

Autophagocytosis of mitochondria is prominent in Alzheimer disease

Autophagocytosis of mitochondria is prominent in Alzheimer disease

Aβ1-42 monomers or oligomers have different effects on autophagy and apoptosis

Aβ1-42-mediated down-regulation of Uch-L1 is dependent on NF-κB activation and impaired BACE1 lysosomal degradation

Beta protein immunoreactivity is found in the majority of neurofibrillary tangles of Alzheimer's disease ⬇️

Beta-amyloid 1-42 monomers, but not oligomers, produce PHF-like conformation of Tau protein

Beta-site APP cleaving enzyme up-regulation induced by 4-hydroxynonenal is mediated by stress-activated protein kinases pathways.

Birth of JAD: 20 Years Later.

CD36 overexpression in human brain correlates with beta-amyloid deposition but not with Alzheimer's disease

Cerebrospinal fluid and neuropathological study in Devic's syndrome. Evidence of intrathecal immune activation

Chronic oxidative stress causes increased tau phosphorylation in M17 neuroblastoma cells

Complete bilateral relapsing ophthalmoplegia in a diabetic patient with a sensory-motor distal polyneuropathy

Creutzfeldt-Jakob disease in the city and district of Genoa: estimated mortality rate in the six year period 1974-1979

Demonstration of a novel neurofilament associated antigen with the neurofibrillary pathology of Alzheimer and related diseases

Direct immunofluorescence in sural nerve biopsies

Dissociated amyloid-beta antibody levels as a serum biomarker for the progression of Alzheimer's disease: a population-based study

Dual Mechanism of Toxicity for Extracellular Injection of Tau Oligomers versus Monomers in Human Tau Mice

Dystrophic neurites infiltrate extracellular neurofibrillary tangles in Alzheimer disease

Early contribution of oxidative glycation in Alzheimer disease

Early glycoxidation damage in brains from Down's syndrome.

Elevation of {beta}-amyloid 1-42 autoantibodies in the blood of amnestic patients with mild cognitive impairment

Endogenous APP derivatives oppositely modulate apoptosis through an autocrine loop

Estrogens Inhibit Amyloid-β-Mediated Paired Helical Filament-Like Conformation of Tau Through Antioxidant Activity and miRNA 218 Regulation in hTau Mice

Evidence that the Amyloid beta Precursor Protein-intracellular domain lowers the stress threshold of neurons and has a "regulated" transcriptional role

Familial progressive subcortical gliosis: presence of prions and linkage to chromosome 17

Fibroblasts from FAD-linked presenilin 1 mutations display a normal unfolded protein response but overproduce Abeta42 in response to tunicamycin

Formic acid treatment exposes hidden neurofilament and tau epitopes in abnormal cytoskeletal filaments from patients with progressive supranuclear palsy and Alzheimer's disease

Frontal Variant of Alzheimer's Disease: A Report of a Novel PSEN1 Mutation

Frontotemporal dementia and corticobasal degeneration in a family with a P301S mutation in tau.

GFAP expression of human Schwann cells in tissue culture

Generalized chorea due to bilateral small, deep cerebral infarcts

Generation of an apoptotic intracellular peptide by gamma-secretase cleavage of Alzheimer's amyloid beta protein precursor.

HLA-DR Schwann cell reactivity in peripheral neuropathies of different origins

Hereditary motor and sensory neuropathy with deafness, mental retardation and absence of large myelinated fibers.

Heterogeneity of water‐soluble amyloid β‐peptide in Alzheimer's disease and Down's syndrome brains ⬇️

Increase of cdk5 is related to neurofibrillary pathology in progressive supranuclear palsy

Increased amyloidogenic secretion in cerebellar granule cells undergoing apoptosis

Increased autophagic degradation of mitochondria in Alzheimer disease

Increased iron and free radical generation in preclinical Alzheimer disease and mild cognitive impairment

Increased oxidative stress involving olfactory neurons in Alzheimer disease

Influence of neuronal location on antigenic properties of neurofibrillary tangles ⬇️

Is amyloid beta-protein glycated in Alzheimer's disease?

Italian multicenter study of dementia: a pathologically verified case of Alzheimer disease

JNK and ERK1/2 pathways have a dual opposite effect on the expression of BACE1.

La función del estrés oxidativo en la patogénesis de la enfermedad de Alzheimer

Lipoperoxidation is selectively involved in progressive supranuclear palsy

Locked-in syndrome in acute inflammatory polyradiculoneuropathy

Mechanisms of phenotypic heterogeneity in prion, Alzheimer and other conformational diseases

Memantine: "hypothesis testing" not "disease modifying" in Alzheimer's disease

Microarray analysis in Alzheimer's disease and normal aging

Microtubule Reduction in Alzheimer's Disease and Aging Is Independent of τ Filament Formation ⬇️

Mitochondrial abnormalities in Alzheimer's disease.

Monoclonal IgM-associated demyelinating peripheral neuropathy: an expression of monoclonal autoimmunity

Monomeric Aβ1-42 and RAGE: key players in neuronal differentiation.

Multiple signaling events in amyloid beta-induced, oxidative stress-dependent neuronal apoptosis

Mutant presenilin 1 increases the expression and activity of BACE1

N-terminal truncated pyroglutamyl beta amyloid peptide Abetapy3-42 shows a faster aggregation kinetics than the full-length Abeta1-42.

Neprylisin decreases uniformly in Alzheimer's disease and in normal aging