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List of works by Madeline Shea

Allosteric effects of the antipsychotic drug trifluoperazine on the energetics of calcium binding by calmodulin

scientific article

An interdomain linker increases the thermostability and decreases the calcium affinity of the calmodulin N-domain

scientific article published on 01 January 2002

Analysis of site-specific interaction parameters in protein-DNA complexes

scientific article published on 01 January 1992

Apo-calmodulin binds with its C-terminal domain to the N-methyl-D-aspartate receptor NR1 C0 region.

scientific article published on 15 October 2003

Backbone and side-chain resonance assignments of (Ca2+)4-calmodulin bound to beta calcineurin A CaMBD peptide.

scientific article published on 16 August 2017

Backbone resonance assignments of complexes of apo human calmodulin bound to IQ motif peptides of voltage-dependent sodium channels NaV1.1, NaV1.4 and NaV1.7.

scientific article published on 04 May 2018

Backbone resonance assignments of complexes of human voltage-dependent sodium channel NaV1.2 IQ motif peptide bound to apo calmodulin and to the C-domain fragment of apo calmodulin

scientific article published on 19 August 2017

Basic interdomain boundary residues in calmodulin decrease calcium affinity of sites I and II by stabilizing helix-helix interactions

scientific article published on 01 February 2003

Biochemical properties of V91G calmodulin: A calmodulin point mutation that deregulates muscle contraction in Drosophila.

scientific article published on December 2004

Bohr effects of the partially-ligated (CN-met) intermediates of hemoglobin as probed by quaternary assembly

scientific article published on 01 August 1994

Ca-Saturated calmodulin binds tightly to the N-terminal domain of A-type fibroblast growth factor homologous factors

scientific article

Calcium binding decreases the stokes radius of calmodulin and mutants R74A, R90A, and R90G

scientific article

Calcium binding to calmodulin mutants having domain-specific effects on the regulation of ion channels

scientific article published on 01 December 2006

Calcium binding to calmodulin mutants monitored by domain-specific intrinsic phenylalanine and tyrosine fluorescence.

scientific article

Calcium triggers reversal of calmodulin on nested anti-parallel sites in the IQ motif of the neuronal voltage-dependent sodium channel NaV1.2.

scientific article published on 9 March 2017

Calcium-dependent energetics of calmodulin domain interactions with regulatory regions of the Ryanodine Receptor Type 1 (RyR1)

scientific article

Calcium-induced conformational switching of Paramecium calmodulin provides evidence for domain coupling

scientific article published on 01 December 2002

Calcium-induced interactions of calmodulin domains revealed by quantitative thrombin footprinting of Arg37 and Arg106.

scientific article published in March 1996

Calmodulin and PI(3,4,5)P₃ cooperatively bind to the Itk pleckstrin homology domain to promote efficient calcium signaling and IL-17A production

scientific article

Discontinuous equilibrium titrations of cooperative calcium binding to calmodulin monitored by 1-D 1H-nuclear magnetic resonance spectroscopy

scientific article published on 01 August 1995

Displacement of alpha-actinin from the NMDA receptor NR1 C0 domain By Ca2+/calmodulin promotes CaMKII binding

scientific article published on 30 June 2007

Energetics of calmodulin domain interactions with the calmodulin binding domain of CaMKII.

scientific article

Energetics of cooperative protein-DNA interactions: comparison between quantitative deoxyribonuclease footprint titration and filter binding

scientific article published on 01 November 1986

Free energy coupling within macromolecules. The chemical work of ligand binding at the individual sites in co-operative systems

scientific article published on 01 October 1983

HEXIM1 is a promiscuous double-stranded RNA-binding protein and interacts with RNAs in addition to 7SK in cultured cells.

scientific article published on 29 March 2007

Interdomain cooperativity of calmodulin bound to melittin preferentially increases calcium affinity of sites I and II.

scientific article published in June 2008

Introduction: twenty five years of the Gibbs Conference on Biothermodynamics

scientific article published on 21 July 2011

Lobe-dependent regulation of ryanodine receptor type 1 by calmodulin.

scientific article published on 15 August 2002

MICAL1 constrains cardiac stress responses and protects against disease by oxidizing CaMKII

scientific article published on 04 August 2020

Opposing orientations of the anti-psychotic drug trifluoperazine selected by alternate conformations of M144 in calmodulin

scientific article

PU.1 binding to ets motifs within the equine infectious anemia virus long terminal repeat (LTR) enhancer: regulation of LTR activity and virus replication in macrophages

scientific article published on April 2004

Paramecium calmodulin mutants defective in ion channel regulation can bind calcium and undergo calcium-induced conformational switching.

scientific article published in June 2000

Phenylalanine fluorescence studies of calcium binding to N-domain fragments of Paramecium calmodulin mutants show increased calcium affinity correlates with increased disorder

scientific article

Proteolytic footprinting titrations for estimating ligand-binding constants and detecting pathways of conformational switching of calmodulin

scientific article published on 01 January 2000

Quantitative DNase footprint titration: a method for studying protein-DNA interactions

scientific article

Quantitative endoproteinase GluC footprinting of cooperative Ca2+ binding to calmodulin: proteolytic susceptibility of E31 and E87 indicates interdomain interactions

scientific article published on 01 January 1995

Quantitative model for gene regulation by lambda phage repressor

scientific article

Recognition of β-calcineurin by the domains of calmodulin: thermodynamic and structural evidence for distinct roles

scientific article

Regulation of calcium/calmodulin-dependent protein kinase II docking to N-methyl-D-aspartate receptors by calcium/calmodulin and alpha-actinin.

scientific article published on 13 October 2002

Structural and Energetic Determinants of Apo Calmodulin Binding to the IQ Motif of the NaV1.2 Voltage-Dependent Sodium Channel

scientific article

Subunit hybridization studies of partially ligated cyanomethemoglobins using a cryogenic method. Evidence for three allosteric states.

scientific article published in January 1990

The NMDA Receptor NR1 C1 Region Bound to Calmodulin: Structural Insights into Functional Differences between Homologous Domains

scientific article

The Nkd EF-hand domain modulates divergent wnt signaling outputs in zebrafish.

scientific article published on 24 November 2017

The OR control system of bacteriophage lambda. A physical-chemical model for gene regulation

scientific article published on 01 January 1985

The neuronal voltage-dependent sodium channel type II IQ motif lowers the calcium affinity of the C-domain of calmodulin.

scientific article published on 8 December 2007

Thermodynamic linkage between calmodulin domains binding calcium and contiguous sites in the C-terminal tail of Ca(V)1.2.

scientific article published on 24 June 2011

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