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List of works by Jean Mazella

A Human TREK-1/HEK Cell Line: A Highly Efficient Screening Tool for Drug Development in Neurological Diseases

scientific article published on October 14, 2011

Astroglial Control of the Antidepressant-Like Effects of Prefrontal Cortex Deep Brain Stimulation.

scientific article

Beta-arrestin is involved in the desensitization but not in the internalization of the somatostatin receptor 2A expressed in CHO cells

scientific article published on 01 April 2002

Binding and internalization of iodinated neurotensin in neuronal cultures from embryonic mouse brain

scientific article published on November 15, 1991

Coexpression of somatostatin receptor subtype 5 affects internalization and trafficking of somatostatin receptor subtype 2.

scientific article published on February 2007

Colocalization of neurotensin receptors and of the neurotensin-degrading enzyme endopeptidase 24-16 in primary cultures of neurons

scientific article published on December 1990

Crucial role of neuron-enriched endosomal protein of 21 kDa in sorting between degradation and recycling of internalized G-protein-coupled receptors.

scientific article published on 7 June 2004

Distribution of NTS3 receptor/sortilin mRNA and protein in the rat central nervous system

scientific journal article

Editorial: Sortilin and Sortilin Partners in Physiology and Pathologies

scientific article published on 11 July 2019

Effects of SR 48692 on neurotensin-induced calcium-activated chloride currents in the Xenopus oocyte expression system: agonist-like activity on the levocabastine-sensitive neurotensin receptor and absence of antagonist effect on the levocabastine i

scientific article published in February 1997

Fighting against depression with TREK-1 blockers: Past and future. A focus on spadin

scientific article published on 03 October 2018

First evidence of protective effects on stroke recovery and post-stroke depression induced by sortilin-derived peptides

scientific article published on 17 July 2019

Fluoxetine Protection in Decompression Sickness in Mice is Enhanced by Blocking TREK-1 Potassium Channel with the "spadin" Antidepressant

scientific article published on 16 February 2016

Focal Adhesion Kinase-Dependent Role of the Soluble Form of Neurotensin Receptor-3/Sortilin in Colorectal Cancer Cell Dissociation

scientific article

Focal adhesion kinase dependent activation of the PI3 kinase pathway by the functional soluble form of neurotensin receptor-3 in HT29 cells

scientific article published on February 8, 2013

Functional roles of the NTS2 and NTS3 receptors.

scientific article published on 26 July 2006

High-affinity neurotensin binding sites in differentiated neuroblastoma N1E115 cells.

scientific article published in April 1984

Identification and characterization of two zebrafish Twik related potassium channels, Kcnk2a and Kcnk2b

scientific article published in Scientific Reports

Identification and expression of a variant isoform of the levocabastine-sensitive neurotensin receptor in the mouse central nervous system

scientific article published on 01 January 1997

Impairement of HT29 Cancer Cells Cohesion by the Soluble Form of Neurotensin Receptor-3.

scientific article

Implication of various forms of neurotensin receptors in the mechanism of internalization of neurotensin in cerebral neurons.

scientific article published in August 1993

In vitro and in vivo regulation of synaptogenesis by the novel antidepressant spadin

scientific article published on 24 March 2015

Increased serum levels of sortilin-derived propeptide after electroconvulsive therapy in treatment-resistant depressed patients

scientific article published on 06 September 2018

Internalization and trafficking of neurotensin via NTS3 receptors in HT29 cells.

scientific article

Internalization of neurotensin in cultured neurons.

scientific article

Internalization-dependent regulation of HT29 cell proliferation by neurotensin.

scientific article published on 25 July 2006

Intracellular dynamics of sst5 receptors in transfected COS-7 cells: maintenance of cell surface receptors during ligand-induced endocytosis

article

Involvement of the neurotensin receptor subtype NTR3 in the growth effect of neurotensin on cancer cell lines.

scientific article published in May 2001

Involvement of the neurotensin receptor-3 in the neurotensin-induced migration of human microglia

scientific article (publication date: 15 February 2003)

Localization of the somatostatin receptor SST2A in rat brain using a specific anti-peptide antibody.

scientific article published in July 1996

Molecular properties of neurotensin receptors in rat brain. Identification of subunits by covalent labeling.

scientific article published in January 1985

Monoiodo-[Trp11]neurotensin, a highly radioactive ligand of neurotensin receptors. Preparation, biological activity, and binding properties to rat brain synaptic membranes

scientific article published on 01 March 1983

Neurotensin and its receptors in the control of glucose homeostasis

scientific article published on November 26, 2012

Neurotensin and neurotensin receptors

scientific article (publication date: July 1999)

Neurotensin is a regulator of insulin secretion in pancreatic beta-cells.

scientific article published on 30 June 2010

Neurotensin protects pancreatic beta cells from apoptosis.

scientific article

Neurotensin receptor-1 and -3 complex modulates the cellular signaling of neurotensin in the HT29 cell line

scientific article (publication date: October 2002)

Neurotensin receptor-2 and -3 are crucial for the anti-apoptotic effect of neurotensin on pancreatic beta-TC3 cells.

scientific article

Neurotensin-induced Erk1/2 phosphorylation and growth of human colonic cancer cells are independent from growth factors receptors activation.

scientific article published on 14 September 2011

Pharmacological, molecular and functional characterization of glial neurotensin receptors

scientific article published on 01 January 1999

Pivotal role of an aspartate residue in sodium sensitivity and coupling to G proteins of neurotensin receptors

scientific article published on 01 February 1999

Porcine odorant-binding protein selectively binds to a human olfactory receptor.

scientific article

Potentiation of Calcium Influx and Insulin Secretion in Pancreatic Beta Cell by the Specific TREK-1 Blocker Spadin.

scientific article published on 25 December 2016

Preferential expression of sst2A over sst2B somatostatin receptor splice variant in rat brain and pituitary.

scientific article

Preparation of neurotensin selectively iodinated on the tyrosine 3 residue. Biological activity and binding properties on mammalian neurotensin receptors

scientific article published on May 16, 1984

Purification of the neurotensin receptor from mouse brain by affinity chromatography

scientific article published on 01 April 1989

Recycling ability of the mouse and the human neurotensin type 2 receptors depends on a single tyrosine residue

scientific article (publication date: 2002)

Regional and cellular distribution of low affinity neurotensin receptor mRNA in adult and developing mouse brain

scientific article published on May 11, 1998

Retroinverso analogs of spadin display increased antidepressant effects

scientific article

Role of TREK-1 in Health and Disease, Focus on the Central Nervous System

article

Serum sortilin-derived propeptides concentrations are decreased in major depressive disorder patients

scientific article published on 4 November 2016

Shedding of the luminal domain of the neurotensin receptor-3/sortilin in the HT29 cell line

scientific article (publication date: 15 November 2002)

Somatostatin-induced regulation of SST(2A) receptor expression and cellsurface availability in central neurons: role of receptor internalization.

scientific article

Sortilin derived propeptide regulation during adipocyte differentiation and inflammation

scientific article published on 2 November 2016

Spadin as a new antidepressant: absence of TREK-1-related side effects.

scientific article

Spadin, a sortilin-derived peptide, targeting rodent TREK-1 channels: a new concept in the antidepressant drug design.

scientific article

Stable expression of the mouse levocabastine-sensitive neurotensin receptor in HEK 293 cell line: binding properties, photoaffinity labeling, and internalization mechanism.

scientific article

Structure, functional expression, and cerebral localization of the levocabastine-sensitive neurotensin/neuromedin N receptor from mouse brain

scientific article

Targeting two-pore domain K(+) channels TREK-1 and TASK-3 for the treatment of depression: a new therapeutic concept.

scientific article

The 100-kDa Neurotensin Receptor Is gp95/Sortilin, A Non-G-Protein-coupled Receptor

scientific article published on October 9, 1998

The Involvement of Sortilin/NTSR3 in Depression as the Progenitor of Spadin and Its Role in the Membrane Expression of TREK-1

scientific article published on 01 January 2018

The anti-apoptotic role of neurotensin.

scientific article published on 04 March 2013

[Sortilin: protein associated with multiple functions]

scientific article published on 01 June 2004