List of works - F M Hoffmann

A Drosophila protein related to the human zinc finger transcription factor PRDII/MBPI/HIV-EP1 is required for dpp signaling.

scientific article published in October 1995

A High-Throughput Screening Strategy to Identify Inhibitors of SSB Protein-Protein Interactions in an Academic Screening Facility

scientific article published on 01 June 2017

A conserved system for dorsal-ventral patterning in insects and vertebrates involving sog and chordin.

scientific article published in July 1995

A genetic screen for modifiers of Drosophila decapentaplegic signaling identifies mutations in punt, Mothers against dpp and the BMP-7 homologue, 60A.

scientific article published in May 1998

A high-throughput method to identify novel senescence-inducing compounds.

scientific article

A new method for removing nonionic detergent that allows reconstitution of dopamine-sensitive adenylate cyclase ⬇️

scientific article published on February 28, 1979

Abl tyrosine kinase and its substrate Ena/VASP have functional interactions with kinesin-1.

scientific article

Biemamides A-E, Inhibitors of the TGF-β Pathway That Block the Epithelial to Mesenchymal Transition ⬇️

scientific article published on 30 August 2018

Biochemical characterization of the Drosophila dpp protein, a member of the transforming growth factor beta family of growth factors

scientific article published on June 1990

Can clues to the molecular defects in chronic myelogenous leukemia come from genetic studies on the Abelson tyrosine kinase in fruit flies?

scientific article published on June 1995

Decapentaplegic: a gene complex affecting morphogenesis in Drosophila melanogaster.

scientific article published in March 1982

Dosage-sensitive modifiers of Drosophila abl tyrosine kinase function: prospero, a regulator of axonal outgrowth, and disabled, a novel tyrosine kinase substrate.

scientific article published on March 1993

Drosophila Dpp signaling is mediated by the punt gene product: A dual ligand-binding type II receptor of the TGFβ receptor family ⬇️

scientific article published on March 24, 1995

Drosophila abelson interacting protein (dAbi) is a positive regulator of abelson tyrosine kinase activity

scientific article (publication date: 16 September 1999)

Drosophila abl and genetic redundancy in signal transduction ⬇️

scientific article published on November 1, 1991

Drosophila melanogaster DNA clones homologous to vertebrate oncogenes: evidence for a common ancestor to the src and abl cellular genes.

scientific article

Drosophila transforming growth factor beta superfamily proteins induce endochondral bone formation in mammals

scientific article

Embryonic expression patterns of the Drosophila decapentaplegic gene: separate regulatory elements control blastoderm expression and lateral ectodermal expression.

scientific article published in January 1994

Enhancing the anticancer properties of cardiac glycosides by neoglycorandomization

scientific article

Evaluation of new migrastatin and dorrigocin congeners unveils cell migration inhibitors with dramatically improved potency.

scientific article

Functional characterization of TtnD and TtnF, unveiling new insights into tautomycetin biosynthesis.

scientific article

Functional characterization of ttmM unveils new tautomycin analogs and insight into tautomycin biosynthesis and activity.

scientific article published on April 2009

Genetic analysis of a Drosophila neural cell adhesion molecule: interaction of fasciclin I and Abelson tyrosine kinase mutations.

scientific article published in February 1990

High-throughput screening identifies idarubicin as a preferential inhibitor of smooth muscle versus endothelial cell proliferation

scientific article (publication date: 2014)

Identification of a fibroblast growth factor-binding protein in Drosophila melanogaster

scientific article published on April 1991

Identification of retinoic acid in a high content screen for agents that overcome the anti-myogenic effect of TGF-beta-1.

scientific article

Increased levels of the Drosophila Abelson tyrosine kinase in nerves and muscles: subcellular localization and mutant phenotypes imply a role in cell-cell interactions ⬇️

scientific article published on December 1, 1992

Inhibition of transforming growth factor-beta1-induced signaling and epithelial-to-mesenchymal transition by the Smad-binding peptide aptamer Trx-SARA

scientific article

Lactimidomycin, iso-migrastatin and related glutarimide-containing 12-membered macrolides are extremely potent inhibitors of cell migration.

scientific article published on February 2009

Learning about cancer genes through invertebrate genetics.

scientific article

Maintainance of Specificity, Information, and Thermostability in Thermophilic Bacillus sp. Glutamine Synthetase ⬇️

scientific article published on January 1, 1976

Mutations in Drosophila enabled and rescue by human vasodilator-stimulated phosphoprotein (VASP) indicate important functional roles for Ena/VASP homology domain 1 (EVH1) and EVH2 domains

scientific article published on August 1998

Mutations in protein-binding hot-spots on the hub protein Smad3 differentially affect its protein interactions and Smad3-regulated gene expression

scientific article

Nox2 and Cyclosporine-Induced Renal Hypoxia.

scientific article published on 4 March 2016

Nucleotide sequences of the Drosophila src and abl homologs: conservation and variability in the src family oncogenes.

scientific article published in December 1983

Phosphorylation of Enabled by the Drosophila Abelson tyrosine kinase regulates the in vivo function and protein-protein interactions of Enabled

scientific article published in January 1998

Practical Model Selection for Prospective Virtual Screening

scientific article published on 18 December 2018

Quantitative microtiter fibronectin fibrillogenesis assay: use in high throughput screening for identification of inhibitor compounds.

scientific article

Reciprocal Regulation of ERα and ERβ Stability and Activity by Diptoindonesin G.

scientific article published on 25 November 2015

Regulation of cell cycle synchronization by decapentaplegic during Drosophila eye development.

scientific article published in January 1997

Smad3 induces atrogin-1, inhibits mTOR and protein synthesis, and promotes muscle atrophy in vivo.

scientific article published on 03 September 2013

Smad4 cooperates with lymphoid enhancer-binding factor 1/T cell-specific factor to increase c-myc expression in the absence of TGF-beta signaling.

scholarly article

TGF-beta family factors in Drosophila morphogenesis.

scientific article

Thalassosamide, a Siderophore Discovered from the Marine-Derived Bacterium Thalassospira profundimaris ⬇️

scientific article published on 25 August 2017

The Drosophila ras oncogenes: structure and nucleotide sequence.

scientific article published in July 1984

Transforming growth factor-β-related genes in Drosophila and vertebrate development ⬇️

scientific article published on December 1, 1991

enabled, a dosage-sensitive suppressor of mutations in the Drosophila Abl tyrosine kinase, encodes an Abl substrate with SH3 domain-binding properties.

scientific article

List of works by F M Hoffmann

A Drosophila protein related to the human zinc finger transcription factor PRDII/MBPI/HIV-EP1 is required for dpp signaling.

A High-Throughput Screening Strategy to Identify Inhibitors of SSB Protein-Protein Interactions in an Academic Screening Facility

A conserved system for dorsal-ventral patterning in insects and vertebrates involving sog and chordin.

A genetic screen for modifiers of Drosophila decapentaplegic signaling identifies mutations in punt, Mothers against dpp and the BMP-7 homologue, 60A.

A high-throughput method to identify novel senescence-inducing compounds.

A new method for removing nonionic detergent that allows reconstitution of dopamine-sensitive adenylate cyclase ⬇️

Abl tyrosine kinase and its substrate Ena/VASP have functional interactions with kinesin-1.

Biemamides A-E, Inhibitors of the TGF-β Pathway That Block the Epithelial to Mesenchymal Transition ⬇️

Biochemical characterization of the Drosophila dpp protein, a member of the transforming growth factor beta family of growth factors

Can clues to the molecular defects in chronic myelogenous leukemia come from genetic studies on the Abelson tyrosine kinase in fruit flies?

Decapentaplegic: a gene complex affecting morphogenesis in Drosophila melanogaster.

Dosage-sensitive modifiers of Drosophila abl tyrosine kinase function: prospero, a regulator of axonal outgrowth, and disabled, a novel tyrosine kinase substrate.

Drosophila Dpp signaling is mediated by the punt gene product: A dual ligand-binding type II receptor of the TGFβ receptor family ⬇️

Drosophila abelson interacting protein (dAbi) is a positive regulator of abelson tyrosine kinase activity

Drosophila abl and genetic redundancy in signal transduction ⬇️

Drosophila melanogaster DNA clones homologous to vertebrate oncogenes: evidence for a common ancestor to the src and abl cellular genes.

Drosophila transforming growth factor beta superfamily proteins induce endochondral bone formation in mammals

Embryonic expression patterns of the Drosophila decapentaplegic gene: separate regulatory elements control blastoderm expression and lateral ectodermal expression.

Enhancing the anticancer properties of cardiac glycosides by neoglycorandomization

Evaluation of new migrastatin and dorrigocin congeners unveils cell migration inhibitors with dramatically improved potency.

Functional characterization of TtnD and TtnF, unveiling new insights into tautomycetin biosynthesis.

Functional characterization of ttmM unveils new tautomycin analogs and insight into tautomycin biosynthesis and activity.

Genetic analysis of a Drosophila neural cell adhesion molecule: interaction of fasciclin I and Abelson tyrosine kinase mutations.

High-throughput screening identifies idarubicin as a preferential inhibitor of smooth muscle versus endothelial cell proliferation

Identification of a fibroblast growth factor-binding protein in Drosophila melanogaster

Identification of retinoic acid in a high content screen for agents that overcome the anti-myogenic effect of TGF-beta-1.

Increased levels of the Drosophila Abelson tyrosine kinase in nerves and muscles: subcellular localization and mutant phenotypes imply a role in cell-cell interactions ⬇️

Inhibition of transforming growth factor-beta1-induced signaling and epithelial-to-mesenchymal transition by the Smad-binding peptide aptamer Trx-SARA

Lactimidomycin, iso-migrastatin and related glutarimide-containing 12-membered macrolides are extremely potent inhibitors of cell migration.

Learning about cancer genes through invertebrate genetics.

Maintainance of Specificity, Information, and Thermostability in Thermophilic Bacillus sp. Glutamine Synthetase ⬇️

Mutations in Drosophila enabled and rescue by human vasodilator-stimulated phosphoprotein (VASP) indicate important functional roles for Ena/VASP homology domain 1 (EVH1) and EVH2 domains

Mutations in protein-binding hot-spots on the hub protein Smad3 differentially affect its protein interactions and Smad3-regulated gene expression

Nox2 and Cyclosporine-Induced Renal Hypoxia.

Nucleotide sequences of the Drosophila src and abl homologs: conservation and variability in the src family oncogenes.

Phosphorylation of Enabled by the Drosophila Abelson tyrosine kinase regulates the in vivo function and protein-protein interactions of Enabled

Practical Model Selection for Prospective Virtual Screening

Quantitative microtiter fibronectin fibrillogenesis assay: use in high throughput screening for identification of inhibitor compounds.

Reciprocal Regulation of ERα and ERβ Stability and Activity by Diptoindonesin G.

Regulation of cell cycle synchronization by decapentaplegic during Drosophila eye development.

Smad3 induces atrogin-1, inhibits mTOR and protein synthesis, and promotes muscle atrophy in vivo.

Smad4 cooperates with lymphoid enhancer-binding factor 1/T cell-specific factor to increase c-myc expression in the absence of TGF-beta signaling.

TGF-beta family factors in Drosophila morphogenesis.

Thalassosamide, a Siderophore Discovered from the Marine-Derived Bacterium Thalassospira profundimaris ⬇️

The Drosophila ras oncogenes: structure and nucleotide sequence.

Transforming growth factor-β-related genes in Drosophila and vertebrate development ⬇️

enabled, a dosage-sensitive suppressor of mutations in the Drosophila Abl tyrosine kinase, encodes an Abl substrate with SH3 domain-binding properties.