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List of works by Michael Lew

A novel mechanism of G protein-coupled receptor functional selectivity. Muscarinic partial agonist McN-A-343 as a bitopic orthosteric/allosteric ligand.

scientific article

Access of blood-borne vasoconstrictors to the arteriolar smooth muscle

scientific article published on July 1, 1992

An improved method for analysis of competitive agonist/antagonist interactions by non-linear regression

scientific article published on 01 May 1997

Analysis of competitive agonist-antagonist interactions by nonlinear regression.

scientific article published on October 1995

Apparent frequency-dependent effect of clonidine on cardiac sympathetic transmission: the role of neuronal uptake

scientific article published on 01 November 1982

Arteriolar reactivity in vivo is influenced by an intramural diffusion barrier.

scientific article

Bad statistical practice in pharmacology (and other basic biomedical disciplines): you probably don't know P

scientific article

Characterization of the clonidine receptor site

scientific article published on 01 February 1983

Clonidine and noradrenaline fail to inhibit vagal induced bradycardia. Evidence against prejunctional alpha-adrenoceptors on vagal varicosities in guinea pig right atria.

scientific article published in July 1983

Disadvantages of cocaine as a neuronal uptake blocking agent: comparison with desipramine in guinea-pig right atrium.

scientific article published in June 1983

Effect of cold storage in University of Wisconsin solution on the responses of porcine hepatic arteries to 5-hydroxytryptamine and bradykinin in vitro.

scientific article published on January 1996

Estimating the risk of rare complications: is the 'rule of three' good enough?

scientific article

Examination of adenosine receptor-mediated relaxation of the pig coronary artery

scientific article published on 01 May 1999

Interpretation of the acetylcholine test of endothelial cell dysfunction in hypertension

scientific article published on December 1, 1992

N-glycosylation determines ionic permeability and desensitization of the TRPV1 capsaicin receptor.

scientific article

On contemporaneous controls, unlikely outcomes, boxes and replacing the 'Student': good statistical practice in pharmacology, problem 3.

scientific article published on 22 September 2008

Phentolamine--an unexpected agonist in the rabbit

scientific article published on March 1984

Principles: when there should be no difference--how to fail to reject the null hypothesis.

scientific article

Protease-activated receptor 2 (PAR2) protein and transient receptor potential vanilloid 4 (TRPV4) protein coupling is required for sustained inflammatory signaling.

scientific article published on 3 January 2013

Release of endogenous ATP during sympathetic nerve stimulation.

scientific article

Reversible inhibition of neuronal uptake by benextramine, an irreversible presynaptic α-adrenoceptor antagonist ⬇️

scientific article published on February 10, 1984

Role of disulfide bridges in the folding, structure and biological activity of omega-conotoxin GVIA.

scientific article

Selective manipulation of neurohumoral control of the cardiac pacemaker by drugs given intrapericardially

scientific article published on 01 April 1987

Side-chain substitutions within angiotensin II reveal different requirements for signaling, internalization, and phosphorylation of type 1A angiotensin receptors.

scientific article published in April 2002

Structure-function relationships of omega-conotoxin GVIA. Synthesis, structure, calcium channel binding, and functional assay of alanine-substituted analogues.

scientific article published on May 1997

Synthesis and biological characterization of a series of analogues of omega-conotoxin GVIA

scientific article published on 01 November 1995

Synthesis and characterization of a selective peptide antagonist of neuropeptide Y vascular postsynaptic receptors.

scientific article published on April 1996

The assessment of antagonist potency under conditions of transient response kinetics

scientific article published on 01 October 1999

The effect of high perfusion rates on the endothelial diffusion barrier in rat mesenteric arteries in vitro

scientific article published on 01 June 1994

Wall thickness to lumen diameter ratios of arteries from SHR and WKY: comparison of pressurised and wire-mounted preparations

scientific article published on 01 November 1992

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