List of works - Marco G. Paggi

Activation of human B-MYB by cyclins

scientific article

Anticancer Properties of the Antipsychotic Drug Chlorpromazine and Its Synergism With Temozolomide in Restraining Human Glioblastoma Proliferation <i>In Vitro</i>

scientific article published on 26 February 2021

Antiproliferative effect of lonidamine on a human glioblastoma multiforme cell line.

scientific article published on July 1990

Cathepsin B inhibition interferes with metastatic potential of human melanoma: an in vitro and in vivo study

scientific article published on 4 August 2010

Changes in membrane potential induced by local anesthetic bupivacaine on mitochondria within Ehrlich ascites tumor cells.

scientific article published in January 1996

Changes of energy metabolism in the germ cells and Ehrlich ascites tumor cells

scientific article published on 01 January 1981

Chlorpromazine induces cytotoxic autophagy in glioblastoma cells via endoplasmic reticulum stress and unfolded protein response

scientific article published on 05 November 2021

Coexpression of Helicobacter pylori's proteins CagA and HspB induces cell proliferation in AGS gastric epithelial cells, independently from the bacterial infection.

scientific article

Correlation between melanogenic and catalase activity in in vitro human melanocytes: a synergic strategy against oxidative stress.

scientific article published on April 2008

Cyclin T2A Gene Maps on Human Chromosome 2q21

article

Cytotoxic effect of the association of BCNU with rhein or lonidamine on a human glioma cell line.

scientific article published on March 1991

Defective human retinoblastoma protein identified by lack of interaction with the E1A oncoprotein.

scientific article published on February 1994

Determination of SGK1 mRNA in non-small cell lung cancer samples underlines high expression in squamous cell carcinomas

scientific article published on 12 January 2012

Drug repurposing against COVID-19: focus on anticancer agents

scientific article published on 12 May 2020

Drug repurposing for the treatment of glioblastoma multiforme.

scientific article published on 28 November 2017

E1A deregulates the centrosome cycle in a Ran GTPase-dependent manner.

scientific article

Effect of adriamycin on electron transport in rat heart, liver, and tumor mitochondria

scientific article published on 01 February 1987

Effect of bcr-abl oligodeoxynucleotides on the clonogenic growth of chronic myelogenous leukaemia cells

scientific article published on 01 June 1997

Effect of hyperthermia on electron transport in Ehrlich ascites tumor mitochondria

scientific article published on 01 June 1987

Effect of lonidamine on human malignant gliomas: biochemical studies

scientific article published on 01 November 1988

Effect of lonidamine on the energy metabolism of Ehrlich ascites tumor cells

scientific article published on 01 November 1981

Effects of Lonidamine on murine and human tumor cells in vitro. A morphological and biochemical study

scientific article published on 01 January 1984

Emerging roles of DNA tumor viruses in cell proliferation: new insights into genomic instability.

scientific article published on September 2003

Energy metabolism of adriamycin-sensitive and -resistant Ehrlich ascites tumor cells.

scientific article

Enhancement of doxorubicin content by the antitumor drug lonidamine in resistant ehrlich ascites tumor cells through modulation of energy metabolism

scientific article published on 01 October 1998

Expression of AP-2 transcription factor and of its downstream target genes c-kit, E-cadherin and p21 in human cutaneous melanoma

article

Ferritin light chain down-modulation generates depigmentation in human metastatic melanoma cells by influencing tyrosinase maturation.

scientific article published on March 2006

Functional analysis of pRb2/p130 interaction with cyclins

scientific article published on 01 May 1996

Gender-related disparities in non-small cell lung cancer.

scientific article published on 09 September 2010

Genetic and epigenetic alterations as hallmarks of the intricate road to cancer.

scientific article published on September 2003

Glucose metabolism in adriamycin-sensitive and -resistant LoVo human colon carcinoma cells.

scientific article

Glucose utilization by tumor cells: a post-translational modification of mitochondrial hexokinase may play a regulatory role.

scientific article published on July 1991

Glycolysis and growth rate in normal and in hexokinase-transfected NIH-3T3 cells.

scientific article published on January 1994

Growth Control by the Retinoblastoma Gene Family

scientific article published on January 1, 2003

Hepatitis C virus core protein modulates pRb2/p130 expression in human hepatocellular carcinoma cell lines through promoter methylation

scientific article

Identification of protein-protein interactions of human HtrA1.

scientific article

In vitro and in vivo tumor growth inhibition by a p16-mimicking peptide in p16INK4A-defective, pRb-positive human melanoma cells.

scientific article published on March 2005

Inhibition of membrane redox activity by rhein and adriamycin in human glioma cells

scientific article published on 01 December 1992

Interaction between the Cdk2/cyclin A complex and a small molecule derived from the pRb2/p130 spacer domain: a theoretical model.

scientific article published on 13 August 2007

Interaction between the human papillomavirus 16 E7 oncoprotein and gelsolin ignites cancer cell motility and invasiveness

scientific article published on 08 April 2016

Interplay between the antimetastatic nm23 and the Retinoblastoma-related Rb2/p130 genes in promoting neuronal differentiation of PC12 cells

article

Intracellular presence of insulin and its phosphorylated receptor in non-small cell lung cancer.

scientific article published in December 2009

Lonidamine in the combined treatment of malignant gliomas. A randomized study.

scientific article published in July 1990

Lonidamine, a selective inhibitor of aerobic glycolysis of murine tumor cells

scientific article published on 01 March 1981

Modulation of adriamycin uptake by lonidamine in Ehrlich ascites tumor cells

scientific article published on 01 December 1988

Multiple interference of the human papillomavirus-16 E7 oncoprotein with the functional role of the metastasis suppressor Nm23-H1 protein.

scientific article published on August 2006

New insights in endometrial carcinogenesis.

scientific article published on July 2012

Pattern of Expression of Cyclin T1 in Human Tissues

scientific article published on 01 June 2001

Pkn is a novel partner of cyclin T2a in muscle differentiation

scientific journal article

Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy

scientific article published on 8 October 2015

Protease-mediated arsenic prodrug strategy in cancer and infectious diseases: a hypothesis for targeted activation.

scientific article published in March 2008

Protein synthetic activity and adenylate energy charge in Rhein-treated cultured human glioma cells.

scientific article

Purification and characterization of a bindable form of mitochondrial bound hexokinase from the highly glycolytic AS-30D rat hepatoma cell line

scientific article published on 01 February 1988

RB1 oncosuppressor gene over-expression inhibits tumor progression and induces melanogenesis in metastatic melanoma cells

article

Reducing the risk of overdiagnosis in lung cancer: A support from molecular biology

scientific article published on 01 September 2011

Repurposing chlorpromazine in the treatment of glioblastoma multiforme: analysis of literature and forthcoming steps

scientific article published on 31 January 2020

Retinoblastoma family proteins as key targets of the small DNA virus oncoproteins.

scientific article published on August 2006

Rhein inhibits glucose uptake in Ehrlich ascites tumor cells by alteration of membrane-associated functions

scientific article published on 01 June 1993

SI113, a SGK1 inhibitor, potentiates the effects of radiotherapy, modulates the response to oxidative stress and induces cytotoxic autophagy in human glioblastoma multiforme cells

scientific article published on 19 February 2016

SI113, a specific inhibitor of the Sgk1 kinase activity that counteracts cancer cell proliferation.

scientific article

Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation.

scientific article published on 11 September 2009

The RB-related gene Rb2/p130 in neuroblastoma differentiation and in B-myb promoter down-regulation

article

The Rb2/p130 gene product is a nuclear protein whose phosphorylation is cycle regulated

article

The bad and the good of mesenchymal stem cells in cancer: Boosters of tumor growth and vehicles for targeted delivery of anticancer agents.

scientific article

The effect of gossypol and Lonidamine on electron transport in Ehrlich ascites tumor mitochondria

scientific article published on 01 April 1984

The influence of patient sex on clinical approaches to malignant glioma

scientific article published on 09 October 2019

The kinase inhibitor SI113 induces autophagy and synergizes with quinacrine in hindering the growth of human glioblastoma multiforme cells

scientific article published on 17 May 2019

The membrane-bound hexokinase as a potential marker for malignancy in human gliomas.

scientific article published in July 1990

The role of mitochondrial hexokinase in neoplastic phenotype and its sensitivity to lonidamine

scientific article published on 01 January 1988

The serine protease HtrA1 is upregulated in the human placenta during pregnancy.

scientific article

The small molecule SI113 hinders epithelial-to-mesenchymal transition and subverts cytoskeletal organization in human cancer cells

scientific article published on 16 May 2019

The small molecule SI113 synergizes with mitotic spindle poisons in arresting the growth of human glioblastoma multiforme

scientific article published on 18 November 2017

Understanding the targeting of the RB family proteins by viral oncoproteins to defeat their oncogenic machinery.

scientific article published on February 2013

Unravelling the complexity of T cell abnormalities in common variable immunodeficiency.

scientific article published in March 2007

Wasting lives: the effects of toxic waste exposure on health. The case of Campania, Southern Italy.

scientific article published on 15 July 2011

Who is the boss in the retinoblastoma family? The point of view of Rb2/p130, the little brother.

scientific article published in June 2001

cDNA array technology in melanoma: an overview.

scientific article

rp-120: a common endogenous substrate for insulin and IGF-1 receptor-associated tyrosine kinase activity in the highly malignant AS-30D rat hepatoma cells.

scientific article published in April 1989

List of works by Marco G. Paggi

Activation of human B-MYB by cyclins

Anticancer Properties of the Antipsychotic Drug Chlorpromazine and Its Synergism With Temozolomide in Restraining Human Glioblastoma Proliferation <i>In Vitro</i>

Antiproliferative effect of lonidamine on a human glioblastoma multiforme cell line.

Cathepsin B inhibition interferes with metastatic potential of human melanoma: an in vitro and in vivo study

Changes in membrane potential induced by local anesthetic bupivacaine on mitochondria within Ehrlich ascites tumor cells.

Changes of energy metabolism in the germ cells and Ehrlich ascites tumor cells

Chlorpromazine induces cytotoxic autophagy in glioblastoma cells via endoplasmic reticulum stress and unfolded protein response

Coexpression of Helicobacter pylori's proteins CagA and HspB induces cell proliferation in AGS gastric epithelial cells, independently from the bacterial infection.

Correlation between melanogenic and catalase activity in in vitro human melanocytes: a synergic strategy against oxidative stress.

Cyclin T2A Gene Maps on Human Chromosome 2q21

Cytotoxic effect of the association of BCNU with rhein or lonidamine on a human glioma cell line.

Defective human retinoblastoma protein identified by lack of interaction with the E1A oncoprotein.

Determination of SGK1 mRNA in non-small cell lung cancer samples underlines high expression in squamous cell carcinomas

Drug repurposing against COVID-19: focus on anticancer agents

Drug repurposing for the treatment of glioblastoma multiforme.

E1A deregulates the centrosome cycle in a Ran GTPase-dependent manner.

Effect of adriamycin on electron transport in rat heart, liver, and tumor mitochondria

Effect of bcr-abl oligodeoxynucleotides on the clonogenic growth of chronic myelogenous leukaemia cells

Effect of hyperthermia on electron transport in Ehrlich ascites tumor mitochondria

Effect of lonidamine on human malignant gliomas: biochemical studies

Effect of lonidamine on the energy metabolism of Ehrlich ascites tumor cells

Effects of Lonidamine on murine and human tumor cells in vitro. A morphological and biochemical study

Emerging roles of DNA tumor viruses in cell proliferation: new insights into genomic instability.

Energy metabolism of adriamycin-sensitive and -resistant Ehrlich ascites tumor cells.

Enhancement of doxorubicin content by the antitumor drug lonidamine in resistant ehrlich ascites tumor cells through modulation of energy metabolism

Expression of AP-2 transcription factor and of its downstream target genes c-kit, E-cadherin and p21 in human cutaneous melanoma

Ferritin light chain down-modulation generates depigmentation in human metastatic melanoma cells by influencing tyrosinase maturation.

Functional analysis of pRb2/p130 interaction with cyclins

Gender-related disparities in non-small cell lung cancer.

Genetic and epigenetic alterations as hallmarks of the intricate road to cancer.

Glucose metabolism in adriamycin-sensitive and -resistant LoVo human colon carcinoma cells.

Glucose utilization by tumor cells: a post-translational modification of mitochondrial hexokinase may play a regulatory role.

Glycolysis and growth rate in normal and in hexokinase-transfected NIH-3T3 cells.

Growth Control by the Retinoblastoma Gene Family

Hepatitis C virus core protein modulates pRb2/p130 expression in human hepatocellular carcinoma cell lines through promoter methylation

Identification of protein-protein interactions of human HtrA1.

In vitro and in vivo tumor growth inhibition by a p16-mimicking peptide in p16INK4A-defective, pRb-positive human melanoma cells.

Inhibition of membrane redox activity by rhein and adriamycin in human glioma cells

Interaction between the Cdk2/cyclin A complex and a small molecule derived from the pRb2/p130 spacer domain: a theoretical model.

Interaction between the human papillomavirus 16 E7 oncoprotein and gelsolin ignites cancer cell motility and invasiveness

Interplay between the antimetastatic nm23 and the Retinoblastoma-related Rb2/p130 genes in promoting neuronal differentiation of PC12 cells

Intracellular presence of insulin and its phosphorylated receptor in non-small cell lung cancer.

Lonidamine in the combined treatment of malignant gliomas. A randomized study.

Lonidamine, a selective inhibitor of aerobic glycolysis of murine tumor cells

Modulation of adriamycin uptake by lonidamine in Ehrlich ascites tumor cells

Multiple interference of the human papillomavirus-16 E7 oncoprotein with the functional role of the metastasis suppressor Nm23-H1 protein.

New insights in endometrial carcinogenesis.

Pattern of Expression of Cyclin T1 in Human Tissues

Pkn is a novel partner of cyclin T2a in muscle differentiation

Preclinical model in HCC: the SGK1 kinase inhibitor SI113 blocks tumor progression in vitro and in vivo and synergizes with radiotherapy

Protease-mediated arsenic prodrug strategy in cancer and infectious diseases: a hypothesis for targeted activation.

Protein synthetic activity and adenylate energy charge in Rhein-treated cultured human glioma cells.

Purification and characterization of a bindable form of mitochondrial bound hexokinase from the highly glycolytic AS-30D rat hepatoma cell line

RB1 oncosuppressor gene over-expression inhibits tumor progression and induces melanogenesis in metastatic melanoma cells

Reducing the risk of overdiagnosis in lung cancer: A support from molecular biology

Repurposing chlorpromazine in the treatment of glioblastoma multiforme: analysis of literature and forthcoming steps

Retinoblastoma family proteins as key targets of the small DNA virus oncoproteins.

Rhein inhibits glucose uptake in Ehrlich ascites tumor cells by alteration of membrane-associated functions

SI113, a SGK1 inhibitor, potentiates the effects of radiotherapy, modulates the response to oxidative stress and induces cytotoxic autophagy in human glioblastoma multiforme cells

SI113, a specific inhibitor of the Sgk1 kinase activity that counteracts cancer cell proliferation.

Sgk1 activates MDM2-dependent p53 degradation and affects cell proliferation, survival, and differentiation.

The RB-related gene Rb2/p130 in neuroblastoma differentiation and in B-myb promoter down-regulation

The Rb2/p130 gene product is a nuclear protein whose phosphorylation is cycle regulated

The bad and the good of mesenchymal stem cells in cancer: Boosters of tumor growth and vehicles for targeted delivery of anticancer agents.

The effect of gossypol and Lonidamine on electron transport in Ehrlich ascites tumor mitochondria

The influence of patient sex on clinical approaches to malignant glioma

The kinase inhibitor SI113 induces autophagy and synergizes with quinacrine in hindering the growth of human glioblastoma multiforme cells

The membrane-bound hexokinase as a potential marker for malignancy in human gliomas.

The role of mitochondrial hexokinase in neoplastic phenotype and its sensitivity to lonidamine

The serine protease HtrA1 is upregulated in the human placenta during pregnancy.

The small molecule SI113 hinders epithelial-to-mesenchymal transition and subverts cytoskeletal organization in human cancer cells

The small molecule SI113 synergizes with mitotic spindle poisons in arresting the growth of human glioblastoma multiforme

Understanding the targeting of the RB family proteins by viral oncoproteins to defeat their oncogenic machinery.

Unravelling the complexity of T cell abnormalities in common variable immunodeficiency.

Wasting lives: the effects of toxic waste exposure on health. The case of Campania, Southern Italy.

Who is the boss in the retinoblastoma family? The point of view of Rb2/p130, the little brother.

cDNA array technology in melanoma: an overview.

rp-120: a common endogenous substrate for insulin and IGF-1 receptor-associated tyrosine kinase activity in the highly malignant AS-30D rat hepatoma cells.