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List of works by Manjunatha Kini

A Distinct Functional Site in Ω-Neurotoxins: Novel Antagonists of Nicotinic Acetylcholine Receptors from Snake Venom.

scientific article published on 8 October 2015

A defined α-helix in the bifunctional O-glycosylated natriuretic peptide TcNPa from the venom of Tropidechis carinatus.

scientific article published on 3 March 2015

A general approach to protein folding using thermostable exoshells

scientific article published in 2021

A hypothetical structural role for proline residues in the flanking segments of protein-protein interaction sites.

scientific article published in July 1995

A new cytotoxic polyhydroxysterol from soft coral Sarcophyton trocheliophorum ⬇️

scientific article published on 01 July 2000

A novel approach to the design of potent bioactive peptides by incorporation of proline brackets: antiplatelet effects of Arg-Gly-Asp peptides.

scientific article published in November 1995

A universal method for fishing target proteins from mixtures of biomolecules using isothermal titration calorimetry.

scientific article published on 11 July 2008

Accelerated evolution and molecular surface of venom phospholipase A2 enzymes

scientific article published on 01 February 1999

Accelerated evolution of toxin genes: Exonization and intronization in snake venom disintegrin/metalloprotease genes.

scientific article published on 7 April 2018

Adrenergic and nitrergic responses of the rat isolated anococcygeus muscle to a new toxin (makatoxin I) from the venom of the scorpion Buthus martensi Karsch.

scientific article published in April 1997

Amino acid sequence of trocarin, a prothrombin activator from Tropidechis carinatus venom: its structural similarity to coagulation factor Xa

scientific article published on 01 July 1999

An Integrated Proteomic and Transcriptomic Analysis Reveals the Venom Complexity of the Bullet Ant Paraponera clavata

scientific article published on 14 May 2020

Analysis of Colubroidea snake venoms by liquid chromatography with mass spectrometry: evolutionary and toxinological implications

scientific article published in January 2003

Analysis of the peanut agglutinin molten globule-like intermediate by limited proteolysis.

scientific article

Angio-3, a 10-residue peptide derived from human plasminogen kringle 3, suppresses tumor growth in mice via impeding both angiogenesis and vascular permeability.

scientific article published on 24 April 2018

Anticoagulant proteins from snake venoms: structure, function and mechanism

scientific article

Anticoagulant venom and mammalian secreted phospholipases A(2): protein- versus phospholipid-dependent mechanism of action.

scientific article

Anticoagulants from hematophagous animals

scientific article published on 01 December 2008

Antimicrobial activity of omwaprin, a new member of the waprin family of snake venom proteins

scientific article published on February 2007

Application of isothermal titration calorimetry and column chromatography for identification of biomolecular targets.

scientific article published on 20 January 2011

Are C-type lectin-related proteins derived by proteolysis of metalloproteinase/disintegrin precursor proteins?

scientific article published on 01 November 1996

At-line nanofractionation with parallel mass spectrometry and bioactivity assessment for the rapid screening of thrombin and factor Xa inhibitors in snake venoms.

scientific article published on 18 December 2015

Avathrin: a novel thrombin inhibitor derived from a multicopy precursor in the salivary glands of the ixodid tick, Amblyomma variegatum

scientific article

Beta-cardiotoxin: a new three-finger toxin from Ophiophagus hannah (king cobra) venom with beta-blocker activity.

scientific article

Biophysical characterization of anticoagulant hemextin AB complex from the venom of snake Hemachatus haemachatus.

scientific article

Biosynthetic Oligoclonal Antivenom (BOA) for Snakebite and Next-Generation Treatments for Snakebite Victims

scientific article published on 13 December 2018

Characterization of the interaction of wheat HMGa with linear and four-way junction DNAs

scientific article published on 01 June 2003

Characterization of three edema-inducing phospholipase A2 enzymes from habu (Trimeresurus flavoviridis) venom and their interaction with the alkaloid aristolochic acid

scientific article published on 01 January 1987

Classification and nomenclature of snake venom C-type lectins and related proteins.

scientific article published on 9 April 2009

Comparison of amino terminal region of three isoenzymes of phospholipases A2 (TFV PL-Ia, TFV PL-Ib, TFV PL-X) from Trimeresurus flavoviridis (habu snake) venom and the complete amino acid sequence of the basic phospholipase, TFV PL-X

scientific article published on 01 January 1986

Comparison of protein models minimized by the all-atom and united-atom models in the AMBER force field: correlation of RMS deviation with the crystallographic R factor and size

scientific article published on October 1, 1992

Comparison of proteomic profiles of the venoms of two of the 'Big Four' snakes of India, the Indian cobra (Naja naja) and the common krait (Bungarus caeruleus), and analyses of their toxins.

scientific article published on 08 June 2017

Complement C3 isoforms in Austrelaps superbus

scientific article published on 27 December 2007

Complete amino acid sequence of an acidic, cardiotoxic phospholipase A2 from the venom of Ophiophagus hannah (King Cobra): a novel cobra venom enzyme with "pancreatic loop"

scientific article published on 01 February 1997

Correlation between the enzymatic activity, anticoagulant and antiplatelet effects of phospholipase A2 isoenzymes from Naja nigricollis venom

scientific article published on 01 October 1988

Crystal Structure of Thrombin in Complex with S-Variegin: Insights of a Novel Mechanism of Inhibition and Design of Tunable Thrombin Inhibitors

scientific article

Crystal structure of bucain, a three-fingered toxin from the venom of the Malayan krait (Bungarus candidus)

scientific article published on 01 January 2009

Crystallization and preliminary X-ray analysis of bucain, a novel toxin from the Malayan krait Bungarus candidus

scientific article published on 28 September 2002

Crystallization and preliminary X-ray diffraction analysis of hemextin A: a unique anticoagulant protein from Hemachatus haemachatus venom.

scientific article published on 21 July 2007

Decoding the molecular switches of natriuretic peptides which differentiate its vascular and renal functions.

scientific article

Denmotoxin, a three-finger toxin from the colubrid snake Boiga dendrophila (Mangrove Catsnake) with bird-specific activity.

scientific article published on 24 July 2006

Development of Plate Reader and On-Line Microfluidic Screening to Identify Ligands of the 5-Hydroxytryptamine Binding Protein in Venoms

scientific article published on 24 June 2015

Development of an Online Cell-Based Bioactivity Screening Method by Coupling Liquid Chromatography to Flow Cytometry with Parallel Mass Spectrometry.

scientific article published on 5 April 2016

Development of bioanalytical assays for variegin, a peptide-based bivalent direct thrombin inhibitor.

scientific article published on 10 May 2017

Dissection approach: a simple strategy for the identification of the step of action of anticoagulant agents in the blood coagulation cascade

scientific article published on 01 January 2005

Do we know the complete sequence of metalloproteinase and nonenzymatic platelet aggregation inhibitor (disintegrin) precursor proteins?

scientific article published on 01 September 1995

Effect of C-terminal amidation on folding and disulfide-pairing of alpha-conotoxin ImI

scientific article published on 01 October 2005

Effect of snake venom procoagulants on snake plasma: implications for the coagulation cascade of snakes.

scientific article

Effects of snake venom proteins on blood platelets.

scientific article published on January 1990

Effects of tannins from Geum japonicum on the catalytic activity of thrombin and factor Xa of blood coagulation cascade

scientific article published on 01 November 1998

Eggs-only diet: its implications for the toxin profile changes and ecology of the marbled sea snake (Aipysurus eydouxii).

scientific article

Eggshell matrix protein mimics: designer peptides to induce the nucleation of calcite crystal aggregates in solution.

scientific article

Electrospray liquid chromatography/mass spectrometry fingerprinting of Acanthophis (death adder) venoms: taxonomic and toxinological implications

scientific article published on 01 January 2002

Enzymatic toxins from snake venom: structural characterization and mechanism of catalysis

scientific article published on 17 May 2011

Evolution of three-finger toxins - a versatile mini protein scaffold.

scientific article

Exactin: A specific inhibitor of Factor X activation by extrinsic tenase complex from the venom of Hemachatus haemachatus.

scientific article published on 25 August 2016

Excitement ahead: structure, function and mechanism of snake venom phospholipase A2 enzymes

scientific article

Exogenous factors from animal sources that induce platelet aggregation

scientific article published on 01 January 2001

Exogenous inhibitors of platelet aggregation from animal sources

scientific article published on 01 January 2001

Fasxiator, a novel factor XIa inhibitor from snake venom, and its site-specific mutagenesis to improve potency and selectivity.

scientific article published on 24 December 2014

Flanking proline residues identify the L-type Ca2+ channel binding site of calciseptine and FS2.

scientific article

Formation of transient amorphous calcium carbonate precursor in quail eggshell mineralization: an in vitro study.

scientific article

From snake venom toxins to therapeutics--cardiovascular examples.

scientific article published on 04 April 2011

Gene Structures of Trocarin D and Coagulation Factor X, Two Functionally Diverse Prothrombin Activators from Australian Rough Scaled Snake

article

Gene duplication of coagulation factor V and origin of venom prothrombin activator in Pseudonaja textilis snake.

scientific article

Group D prothrombin activators from snake venom are structural homologues of mammalian blood coagulation factor Xa.

scientific article

Haemolytic activity of stonustoxin from stonefish (Synanceja horrida) venom: pore formation and the role of cationic amino acid residues ⬇️

scientific article published on August 1, 1997

Hemextin AB Complex – A Snake Venom Anticoagulant Protein Complex That Inhibits Factor VIIa Activity

Hemextin AB complex, a unique anticoagulant protein complex from Hemachatus haemachatus (African Ringhals cobra) venom that inhibits clot initiation and factor VIIa activity.

scientific article published on 4 October 2005

INN-toxin, a highly lethal peptide from the venom of Indian cobra (Naja naja) venom-Isolation, characterization and pharmacological actions.

scientific article published on 7 August 2008

Identification and Structural Characterization of a New Three-Finger Toxin Hemachatoxin from Hemachatus haemachatus Venom

scientific article

Identification and characterisation of novel inhibitors on extrinsic tenase complex from Bungarus fasciatus (banded krait) venom

scientific article published on 10 July 2014

Identification of a novel family of proteins in snake venoms. Purification and structural characterization of nawaprin from Naja nigricollis snake venom

scientific article

Identification of a novel family of snake venom proteins Veficolins from Cerberus rynchops using a venom gland transcriptomics and proteomics approach.

scientific article

Identification of a α-helical molten globule intermediate and structural characterization of β-cardiotoxin, an all β-sheet protein isolated from the venom of Ophiophagus hannah (king cobra)

scientific article published on 04 April 2019

Identification of novel proteins from the venom of a cryptic snake Drysdalia coronoides by a combined transcriptomics and proteomics approach.

scientific article

In Vitro Mode of Action and Anti-thrombotic Activity of Boophilin, a Multifunctional Kunitz Protease Inhibitor from the Midgut of a Tick Vector of Babesiosis, Rhipicephalus microplus

scientific article

In vitro study of magnesium-calcite biomineralization in the skeletal materials of the seastar Pisaster giganteus.

scientific article published in January 2007

Induction of mitochondrial permeability transition and cytochrome C release in the absence of caspase activation is insufficient for effective apoptosis in human leukemia cells

scientific article published on 01 March 2000

Interrogating the Venom of the Viperid Snake Sistrurus catenatus edwardsii by a Combined Approach of Electrospray and MALDI Mass Spectrometry

scientific article

Isolation and purification of superbins I and II from Austrelaps superbus (copperhead) snake venom and their anticoagulant and antiplatelet effects

scientific article published on 01 August 1997

Isthmin exerts pro-survival and death-promoting effect on endothelial cells through alphavbeta5 integrin depending on its physical state.

scientific article

Isthmin is a novel secreted angiogenesis inhibitor that inhibits tumour growth in mice

scientific journal article

JNK pathway restricts DENV2, ZIKV and CHIKV infection by activating complement and apoptosis in mosquito salivary glands

scientific article published on 10 August 2020

Krait natriuretic peptide (KNP): a non-classical NP

scientific article published on 29 August 2013

Metalloproteases Affecting Blood Coagulation, Fibrinolysis and Platelet Aggregation from Snake Venoms: Definition and Nomenclature of Interaction Sites

scientific article

Microfluidic Chip-Based Online Screening Coupled to Mass Spectrometry: Identification of Inhibitors of Thrombin and Factor Xa.

scientific article published on 31 August 2015

Milestones and future prospects in snake venom research.

scientific article published on 17 September 2012

Mimicking the function of eggshell matrix proteins: the role of multiplets of charged amino acid residues and self-assembly of peptides in biomineralization.

scientific article published in August 2005

Molecular evolution and phylogeny of elapid snake venom three-finger toxins

scientific article (publication date: July 2003)

Molecular moulds with multiple missions: functional sites in three-finger toxins

scientific article

Mosquito saliva re-shapes alphavirus infection and immunopathogenesis.

scientific article published on 28 March 2018

NMR structure of bucandin, a neurotoxin from the venom of the Malayan krait (Bungarus candidus)

scientific article

Neuromuscular effects of candoxin, a novel toxin from the venom of the Malayan krait (Bungarus candidus).

scientific article

Neurotoxicity fingerprinting of venoms using on-line microfluidic AChBP profiling

scientific article published on 04 May 2018

Non-conventional toxins from Elapid venoms.

scientific article

Nucleotide sequence determines the accelerated rate of point mutations

scientific article published on 01 April 2010

Ohanin, a novel protein from king cobra venom, induces hypolocomotion and hyperalgesia in mice.

scientific article

Peptides derived from human decorin leucine-rich repeat 5 inhibit angiogenesis.

scientific article published on 27 May 2005

Pharmacological activity of the interdomain segment between metalloproteinase and disintegrin domains

scientific article published on 01 April 1997

Pharmacological characterisation of a neurotoxin from the venom of Boiga dendrophila (mangrove catsnake).

scientific article

Phospholipase A(2) with platelet aggregation inhibitor activity from Austrelaps superbus venom: protein purification and cDNA cloning.

scientific article published in March 2000

Prediction of potential protein-protein interaction sites from amino acid sequence. Identification of a fibrin polymerization site.

scientific article published in April 1996

Procoagulant proteins from snake venoms.

scientific article

Proline brackets and identification of potential functional sites in proteins: Toxins to therapeutics

scientific article published on 01 November 1998

Protein Folding Determinants:  Structural Features Determining Alternative Disulfide Pairing in α- and χ/λ-Conotoxins † , ‡

scientific article

Proteomic Deep Mining the Venom of the Red-Headed Krait,

scientific article published on 13 September 2018

Proteomic comparisons of venoms of long-term captive and recently wild-caught Eastern brown snakes (Pseudonaja textilis) indicate venom does not change due to captivity

scientific article published on 27 May 2016

Pseutarin C, a prothrombin activator from Pseudonaja textilis venom: its structural and functional similarity to mammalian coagulation factor Xa-Va complex.

scientific article

Purification and partial biochemical characterization of an edema inducing phospholipase A2 from Vipera russelli (Russell's viper) snake venom

scientific article published on 01 January 1988

Purification and properties of three new phospholipase A2 isoenzymes from Micropechis ikaheka venom

scientific article published on 01 February 2001

Purification, characterization, and amino acid sequence determination of acanthins, potent inhibitors of platelet aggregation from Acanthophis antarcticus (common death adder) venom.

scientific article published in June 1998

Purification, characterization, and in vitro mineralization studies of a novel goose eggshell matrix protein, ansocalcin.

scientific article published in June 2012

Putting the brakes on snake venom evolution: the unique molecular evolutionary patterns of Aipysurus eydouxii (Marbled sea snake) phospholipase A2 toxins.

scientific article

Rapid method for separation and purification of four isoenzymes of phosphodiesterase from Trimeresurus flavoviridis (Habu snake) venom

scientific article published on 01 May 1984

Rapid simultaneous detection of two orchid viruses using LC- and/or MALDI-mass spectrometry.

scientific article

Recombinant antitoxic and antiinflammatory factor from the nonvenomous snake Python reticulatus: phospholipase A2 inhibition and venom neutralizing potential.

scientific article

Regulation of expression of venom toxins: silencing of prothrombin activator trocarin D by AG-rich motifs

scientific article published on 16 March 2016

Rhodocetin, a novel platelet aggregation inhibitor from the venom of Calloselasma rhodostoma (Malayan pit viper): synergistic and noncovalent interaction between its subunits

scientific article published on 01 June 1999

Ringhalexin from Hemachatus haemachatus: A novel inhibitor of extrinsic tenase complex

scientific article published on 13 May 2016

Role of accelerated segment switch in exons to alter targeting (ASSET) in the molecular evolution of snake venom proteins

scientific article

Role of enzymatic activity in the antiplatelet effects of a phospholipase A2 from Ophiophagus hannah snake venom

scientific article published on 01 January 1997

Scaffold stability and P14′ residue steric hindrance in the differential inhibition of FXIIa by <i>Aedes aegypti</i> trypsin inhibitor versus Infestin-4

scientific article published in 2022

Serine proteases affecting blood coagulation and fibrinolysis from snake venoms

scientific article

Sexual differences in the sialomes of the zebra tick, Rhipicephalus pulchellus.

scientific article

Snake Genome Sequencing: Results and Future Prospects

scientific article

Snake bites and hemostasis/thrombosis

scientific article published on 27 September 2013

Snake venom natriuretic peptides: Potential molecular probes.

scientific article

Snake venom prothrombin activators similar to blood coagulation factor Xa.

scientific article

Solution structures of two structural isoforms of CMrVIA chi/lambda-conotoxin

scientific article published on 01 August 2006

Stonustoxin is a novel lethal factor from stonefish (Synanceja horrida) venom. cDNA cloning and characterization.

scientific article published on October 1996

Structural Characterization of Myotoxic Ecarpholin S From Echis carinatus Venom

scientific article

Structural determinants in protein folding: a single conserved hydrophobic residue determines folding of EGF domains.

scientific article published on 24 October 2012

Structural determinants of protein folding.

scientific article

Structural domains in venom proteins: evidence that metalloproteinases and nonenzymatic platelet aggregation inhibitors (disintegrins) from snake venoms are derived by proteolysis from a common precursor

scientific article published on March 1, 1992

Structure of two genes encoding parallel prothrombin activators in Tropidechis carinatus snake: gene duplication and recruitment of factor X gene to the venom gland.

scientific article published in January 2007

Structure, function and evolution of three-finger toxins: mini proteins with multiple targets

scientific article

Structure-function relationship of avian eggshell matrix proteins: a comparative study of two major eggshell matrix proteins, ansocalcin and OC-17.

scientific article published in March 2005

Structure-function relationships and mechanism of anticoagulant phospholipase A2 enzymes from snake venoms

scientific article

Structure-function relationships of phospholipases. I: Prediction of presynaptic neurotoxicity

scientific article published on 01 January 1986

Structure-function relationships of phospholipases. II: Charge density distribution and the myotoxicity of presynaptically neurotoxic phospholipases.

scientific article

Studies on snake venom enzymes: Part I. Purification of ATPase, a toxic component of Naja naja venom & its inhibition by potassium gymnemate

scientific article published on 01 April 1982

Studies on snake venom enzymes: Part II--Partial characterization of ATPases from Russell's viper (Vipera russelli) venom & their interaction with potassium gymnemate

scientific article published on 01 October 1982

Tail wags the dog: activity of krait natriuretic peptide is determined by its C-terminal tail in a natriuretic peptide receptor-independent manner.

scientific article

Tamulustoxin: a novel potassium channel blocker from the venom of the Indian red scorpion Mesobuthus tamulus.

scientific article

The First Intrinsic Tenase Complex Inhibitor with Serine Protease Structure Offers a New Perspective in Anticoagulant Therapy

scientific article published on 20 September 2018

The Procoagulant Snake Venom Serine Protease Potentially Having a Dual, Blood Coagulation Factor V and X-Activating Activity

scientific article published on 29 May 2020

The atomic resolution structure of bucandin, a novel toxin isolated from the Malayan krait, determined by direct methods

scientific article

The atomic resolution structure of bucandin, a novel toxin isolated from the malayan krait, determined by direct methods. erratum

scientific article published on 01 December 2000

The intriguing world of prothrombin activators from snake venom

scientific article

The king cobra genome reveals dynamic gene evolution and adaptation in the snake venom system

scientific article

The nonenzymatic subunit of pseutarin C, a prothrombin activator from eastern brown snake (Pseudonaja textilis) venom, shows structural similarity to mammalian coagulation factor V.

scientific article published in May 2003

The recruitment of blood coagulation factor X into snake venom gland as a toxin: the role of promoter cis-elements in its expression

scientific article published on 01 September 2009

The venom gland transcriptome of the Desert Massasauga rattlesnake (Sistrurus catenatus edwardsii): towards an understanding of venom composition among advanced snakes (Superfamily Colubroidea).

scientific article

Toxins Are an Excellent Source of Therapeutic Agents against Cardiovascular Diseases

scientific article published on 28 June 2018

Toxins for decoding interface selectivity in nicotinic acetylcholine receptors

scientific article published on 28 May 2019

Transcriptomic analysis of the venom gland of the red-headed krait (Bungarus flaviceps) using expressed sequence tags

scientific article

Trocarin, a blood coagulation factor Xa homologue from snake venom, causes inflammation and mitogenesis

scientific article published on 01 December 2003

Unique gene organization of colubrid three-finger toxins: complete cDNA and gene sequences of denmotoxin, a bird-specific toxin from colubrid snake Boiga dendrophila (Mangrove Catsnake).

scientific article

Unusual accelerated rate of deletions and insertions in toxin genes in the venom glands of the pygmy copperhead (Austrelaps labialis) from Kangaroo island

scientific article

Unveiling the complexities of Daboia russelii venom, a medically important snake of India, by tandem mass spectrometry

scientific article

Variegin, a novel fast and tight binding thrombin inhibitor from the tropical bont tick.

scientific article published on 7 August 2007

Venom analysis of long-term captive Pakistan cobra (Naja naja) populations.

scientific article published on 21 October 2009

Venom gland transcriptomics for identifying, cataloging, and characterizing venom proteins in snakes.

scientific article

Widespread Evolution of Molecular Resistance to Snake Venom α-Neurotoxins in Vertebrates

scientific article published on 02 October 2020

X-ray crystallographic analysis of time-dependent binding of guanidine hydrochloride to HEWL: First steps during protein unfolding

scientific article published on 06 November 2018

kappa-Hefutoxin1, a novel toxin from the scorpion Heterometrus fulvipes with unique structure and function. Importance of the functional diad in potassium channel selectivity

scientific article

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