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List of works by Michelle M McDonald

Adipose, Bone, and Myeloma: Contributions from the Microenvironment.

scientific article published on 24 June 2016

Augmentation of autologous bone graft by a combination of bone morphogenic protein and bisphosphonate increased both callus volume and strength

scientific article published on February 2013

Bisphosphonate-laden acrylic bone cement: mechanical properties, elution performance, and in vivo activity.

scientific article published in November 2008

Bolus or weekly zoledronic acid administration does not delay endochondral fracture repair but weekly dosing enhances delays in hard callus remodeling.

scientific article

Bone metastasis: the importance of the neighbourhood.

scientific article published on May 2016

Bone remodeling during fracture repair: The cellular picture.

scientific article published on 25 July 2008

Characterization of the bone phenotype and fracture repair in osteopetrotic incisors absent rats

scientific article published on 03 December 2010

Dkk1 KO Mice Treated with Sclerostin Antibody Have Additional Increases in Bone Volume

scientific article published on 29 May 2018

Endochondral fracture healing with external fixation in the Sost knockout mouse results in earlier fibrocartilage callus removal and increased bone volume fraction and strength.

scientific article published on 30 October 2014

Homozygous Dkk1 Knockout Mice Exhibit High Bone Mass Phenotype Due to Increased Bone Formation

scientific article published on 6 November 2017

Inhibiting the osteocyte-specific protein sclerostin increases bone mass and fracture resistance in multiple myeloma

scientific article

Inhibition of sclerostin by systemic treatment with sclerostin antibody enhances healing of proximal tibial defects in ovariectomized rats

scientific article published on 27 March 2012

Intermittent PTH(1-34) does not increase union rates in open rat femoral fractures and exhibits attenuated anabolic effects compared to closed fractures.

scientific article

Loss of the Vitamin D Receptor in Human Breast Cancer Cells Promotes Epithelial to Mesenchymal Cell Transition and Skeletal Colonization

scientific article published on 25 June 2019

Matrix metalloproteinase-driven endochondral fracture union proceeds independently of osteoclast activity

scientific article published on 01 July 2013

Mechanical load increases in bone formation via a sclerostin-independent pathway.

scientific article published in November 2014

Modeling bone morphogenetic protein and bisphosphonate combination therapy in wild-type and Nf1 haploinsufficient mice

scientific article published on 01 January 2008

Models of tibial fracture healing in normal and Nf1-deficient mice

scientific article published on 01 August 2008

Modulation of endochondral ossification by MEK inhibitors PD0325901 and AZD6244 (Selumetinib).

scientific article

Myeloma-modified adipocytes exhibit metabolic dysfunction and a senescence-associated secretory phenotype (SASP)

scientific article published on 20 November 2020

Neuropeptide Y modulates fracture healing through Y1 receptor signaling.

scientific article published on 3 June 2013

Optimal timing of a single dose of zoledronic acid to increase strength in rat fracture repair.

scientific article

Osteoclasts control reactivation of dormant myeloma cells by remodelling the endosteal niche.

scientific article

Polyostotic hyperostosis in a domestic shorthair cat

scientific article published on 01 May 2014

Rapid cell culture and pre-clinical screening of a transforming growth factor-beta (TGF-beta) inhibitor for orthopaedics.

scientific article

Sclerostin Antibody Augments the Anabolic Bone Formation Response in a Mouse Model of Mechanical Tibial Loading

scientific article published on 29 November 2017

Sclerostin Antibody Increases Callus Size and Strength but does not Improve Fracture Union in a Challenged Open Rat Fracture Model.

scientific article published on 8 April 2017

Sclerostin antibody enhances bone formation in a rat model of distraction osteogenesis.

scientific article published on 8 September 2017

Sclerostin: an Emerging Target for the Treatment of Cancer-Induced Bone Disease.

scientific article published on 27 September 2017

Signaling between tumor cells and the host bone marrow microenvironment.

scientific article

The murine stanniocalcin 2 gene is a negative regulator of postnatal growth

scientific journal article

The skeletal cell-derived molecule sclerostin drives bone marrow adipogenesis

scientific article published on 29 April 2017

Zoledronic acid improves femoral head sphericity in a rat model of perthes disease.

scientific article published on 25 February 2005