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Authors whose works are in public domain in at least one jurisdiction

List of works by Toren Finkel

53BP1 inhibits homologous recombination in Brca1-deficient cells by blocking resection of DNA breaks

scientific article

A Critical Role of Mitochondrial Phosphatase Ptpmt1 in Embryogenesis Reveals a Mitochondrial Metabolic Stress-Induced Differentiation Checkpoint in Embryonic Stem Cells ⬇️

scientific article published on October 10, 2011

A Fbxo48 inhibitor prevents pAMPKα degradation and ameliorates insulin resistance

scientific article published on 25 January 2021

A Metabolic Basis for Endothelial-to-Mesenchymal Transition.

scientific article published on 7 February 2018

A fluorescence-based imaging method to measure in vitro and in vivo mitophagy using mt-Keima

scientific article published on 13 July 2017

A potent tumor-selective ERK pathway inactivator with high therapeutic index

A role for the NAD-dependent deacetylase Sirt1 in the regulation of autophagy

scientific article

A selective requirement for 53BP1 in the biological response to genomic instability induced by Brca1 deficiency

scientific article

AMPK-mediated activation of MCU stimulates mitochondrial Ca2+ entry to promote mitotic progression

scientific article published on 11 March 2019

Assessment of cardiac function in mice lacking the mitochondrial calcium uniporter

scientific article

Assessment of mitophagy in mt-Keima Drosophila revealed an essential role of the PINK1-Parkin pathway in mitophagy induction in vivo

scientific article published on 23 May 2019

Atg7 modulates p53 activity to regulate cell cycle and survival during metabolic stress

scientific article

Augmented Wnt signaling in a mammalian model of accelerated aging

scientific journal article

Autophagy and unfolded protein response (UPR) regulate mammary gland involution by restraining apoptosis-driven irreversible changes

article

Autophagy goes nuclear

scientific article published on 01 October 2020

Autophagy regulates endothelial cell processing, maturation and secretion of von Willebrand factor

scientific article

Autophagy-dependent metabolic reprogramming sensitizes TSC2-deficient cells to the antimetabolite 6-aminonicotinamide

scientific article

BRCA1 is an essential regulator of heart function and survival following myocardial infarction ⬇️

scientific article published on December 20, 2011

Bmi1 regulates mitochondrial function and the DNA damage response pathway

scientific article

Breathing lessons: Tor tackles the mitochondria

scientific article

Caenorhabditis elegans UCP4 protein controls complex II-mediated oxidative phosphorylation through succinate transport

scientific article

Cardiac mitochondria: a surprise about size

scientific article published on 24 January 2015

Celastrol Protects against Obesity and Metabolic Dysfunction through Activation of a HSF1-PGC1α Transcriptional Axis

scientific article published on 2 September 2015

Cellular mechanisms and physiological consequences of redox-dependent signalling

scientific article published on June 2014

Coordination of mitochondrial bioenergetics with G1 phase cell cycle progression

scientific article

Cyclin B1/Cdk1 coordinates mitochondrial respiration for cell-cycle G2/M progression

scientific journal article

Cyclophilin D-mediated regulation of the permeability transition pore is altered in mice lacking the mitochondrial calcium uniporter

scientific article published on 01 February 2019

EMRE is essential for mitochondrial calcium uniporter activity in a mouse model

scientific article published on 27 February 2020

Endothelial progenitor cells

scientific article

Fatty acid oxidation in macrophage polarization.

scientific article published in March 2016

Guidelines for the use and interpretation of assays for monitoring autophagy

scientific article

Human mesenchymal stem cells exert potent antitumorigenic effects in a model of Kaposi's sarcoma

scientific article

Identification of a specific molecular repressor of the peroxisome proliferator-activated receptor gamma Coactivator-1 alpha (PGC-1alpha).

scientific article

Identification of the transcription factor Miz1 as an essential regulator of diphthamide biosynthesis using a CRISPR-mediated genome-wide screen

scientific article published on 15 October 2020

Impact papers on aging in 2009.

scientific article

Increased mammalian lifespan and a segmental and tissue-specific slowing of aging after genetic reduction of mTOR expression

scientific article

Inhibiting glycolytic metabolism enhances CD8+ T cell memory and antitumor function.

scientific article published on 16 September 2013

Intact endothelial autophagy is required to maintain vascular lipid homeostasis

scientific article published on 24 November 2015

Interactions between E2F1 and SirT1 regulate apoptotic response to DNA damage

scientific article

Interplay among BRCA1, SIRT1, and Survivin during BRCA1-associated tumorigenesis

scientific article published on October 2008

Key tissue targets responsible for anthrax-toxin-induced lethality

scientific article

MICU1 Serves as a Molecular Gatekeeper to Prevent In Vivo Mitochondrial Calcium Overload

scientific article published on 27 July 2016

Macrophage fatty acid oxidation inhibits atherosclerosis progression

scientific article published on 09 January 2019

Measuring In Vivo Mitophagy

scientific article

Metabolic Regulation by the Mitochondrial Phosphatase PTPMT1 Is Required for Hematopoietic Stem Cell Differentiation ⬇️

scientific article published on January 3, 2013

Metabolism meets autophagy ⬇️

scientific article published on December 15, 2010

MitoRCA-seq reveals unbalanced cytocine to thymine transition in Polg mutant mice

scientific article

Mitochondrial Ca2+ Uptake is Tightly Regulated by the C-Terminal End of EMRE

scholarly article

Mitochondrial Membrane Potential Identifies Cells with Enhanced Stemness for Cellular Therapy.

scientific article published on 7 December 2015

Mitochondrial activity regulates T cell memory, self renewal and anti tumor function in CD8+ T cells

scientific article published on 7 November 2013

Mitochondrial dysfunction and oxidative stress mediate the physiological impairment induced by the disruption of autophagy

scientific article

Mitochondrial metabolism modulates differentiation and teratoma formation capacity in mouse embryonic stem cells

scientific article published on 18 August 2008

Mitohormesis

scientific article

Modulating immunometabolism of tumor specific CD8 T cells to enhance T cell based therapy for cancer

scientific article published on 6 November 2014

Modulating immunometabolism of tumor specific mouse and human lymphocytes to enhance T cell based therapy for cancer.

scientific article published on 4 November 2015

Neutrophils with a license to kill: permeabilized, not stirred

scientific article

Nutrient availability regulates SIRT1 through a forkhead-dependent pathway

scientific article published in December 2004

Oncogene-induced senescence results in marked metabolic and bioenergetic alterations ⬇️

scientific article published on April 1, 2012

Oxidant signals and oxidative stress

scientific article

Oxidants painting the cysteine chapel: redox regulation of PTPs

scientific article

Oxidants, metabolism, and stem cell biology ⬇️

scientific article published on October 18, 2011

Protection from obesity and diabetes by blockade of TGF-β/Smad3 signaling

scientific article

Radical medicine: treating ageing to cure disease

scientific article

Reactive oxygen species as mediators of cellular senescence

scientific article

Reciprocal regulation of acetyl-CoA carboxylase 1 and senescence in human fibroblasts involves oxidant mediated p38 MAPK activation

scientific article

Redox regulation of forkhead proteins through a p66shc-dependent signaling pathway

scientific article published on 7 March 2002

Redox-dependent transcriptional regulation

scientific article

Regulation of autophagy by the p300 acetyltransferase

scientific article

Regulation of cellular oncosis by uncoupling protein 2.

scientific article

Regulation of the Werner helicase through a direct interaction with a subunit of protein kinase A

scientific article (publication date: 19 June 2002)

Relief with Rapamycin: mTOR Inhibition Protects against Radiation-Induced Mucositis ⬇️

scientific article published on September 7, 2012

Retraction Note to: Retraction: The NAD-dependent deacetylase SIRT2 is required for programmed necrosis

scientific article published on 01 February 2014

SIRT1 functionally interacts with the metabolic regulator and transcriptional coactivator PGC-1{alpha}

scientific article (publication date: 22 April 2005)

Sensitive Measurement of Mitophagy by Flow Cytometry Using the pH-dependent Fluorescent Reporter mt-Keima

scientific article published on 12 August 2018

Sequential CRISPR-Based Screens Identify LITAF and CDIP1 as the Bacillus cereus Hemolysin BL Toxin Host Receptors

scientific article published on 09 June 2020

Signal Transduction by Mitochondrial Oxidants ⬇️

scientific article published on August 10, 2011

Solid tumor therapy by selectively targeting stromal endothelial cells

scientific article published on 29 June 2016

Sonic hedgehog signaling regulates the mammalian cardiac regenerative response

scientific article published on 17 September 2018

Stem Cells and Oxidants: Too Little of a Bad Thing ⬇️

scientific article published on July 2, 2013

Strategic Positioning and Biased Activity of the Mitochondrial Calcium Uniporter in Cardiac Muscle.

scientific article published on 16 September 2016

Strategic plan for lung vascular research: An NHLBI-ORDR Workshop Report

scientific article

T cell stemness and dysfunction in tumors are triggered by a common mechanism

scientific article

TFEB-driven lysosomal biogenesis is pivotal for PGC1α-dependent renal stress resistance

scientific article

TFEB-driven lysosomal biogenesis is pivotal for PGC1α-dependent renal stress resistance

scientific article published on 06 August 2020

The Emerging Links Between Sirtuins and Autophagy ⬇️

scientific article published on January 1, 2013

The In Vivo Biology of the Mitochondrial Calcium Uniporter

scientific article published on January 2017

The Intersection Of Aging Biology and The Pathobiology of Lung Diseases: A Joint NHLBI/NIA Workshop

scientific article

The Mitochondrial Basis of Aging

scientific article published on March 2016

The NAD-dependent deacetylase SIRT2 is required for programmed necrosis

scientific journal article

The essential autophagy gene ATG7 modulates organ fibrosis via regulation of endothelial-to-mesenchymal transition

scientific article

The ins and outs of mitochondrial calcium.

scientific article published on May 2015

The mammalian longevity-associated gene product p66shc regulates mitochondrial metabolism

scientific article

The mammalian target of rapamycin (mTOR) pathway regulates mitochondrial oxygen consumption and oxidative capacity

scientific article

The physiological role of mitochondrial calcium revealed by mice lacking the mitochondrial calcium uniporter.

scientific article

The role of ZKSCAN3 in the transcriptional regulation of autophagy

scientific article published on 5 June 2017

The role of autophagy in vascular biology

scientific article

The role of mitochondria in aging

scientific article published on 30 July 2018

Tissue-Resident PDGFRα+ Progenitor Cells Contribute to Fibrosis versus Healing in a Context- and Spatiotemporally Dependent Manner

scientific article published on 01 January 2020

Tumorigenesis in tuberous sclerosis complex is autophagy and p62/sequestosome 1 (SQSTM1)-dependent ⬇️

scientific article published on July 11, 2011

Unresolved questions from the analysis of mice lacking MCU expression

scientific article

Wnt Signaling Regulates Hepatic Metabolism ⬇️

scientific article published on February 1, 2011

Xanthine oxidoreductase is an endogenous regulator of cyclooxygenase-2.

scientific article published on 4 November 2004

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