Search filters

List of works by Jeroen P Saeij

A cluster of four surface antigen genes specifically expressed in bradyzoites, SAG2CDXY, plays an important role in Toxoplasma gondii persistence.

scientific article published on 17 March 2008

Admixture and recombination among Toxoplasma gondii lineages explain global genome diversity

scientific article (publication date: 14 August 2012)

Analysis of gene expression during development: lessons from the Apicomplexa.

scientific article

Bioluminescence imaging of Toxoplasma gondii infection in living mice reveals dramatic differences between strains.

scientific article

Cactin is essential for G1 progression in Toxoplasma gondii.

scientific article published on 9 April 2012

Cell death of gamma interferon-stimulated human fibroblasts upon Toxoplasma gondii infection induces early parasite egress and limits parasite replication

scientific article

Clonal and atypical Toxoplasma strain differences in virulence vary with mouse sub-species

scientific article published on 22 November 2018

Communication between Toxoplasma gondii and its host: impact on parasite growth, development, immune evasion, and virulence

scientific article

De novo reconstruction of the Toxoplasma gondii transcriptome improves on the current genome annotation and reveals alternatively spliced transcripts and putative long non-coding RNAs

scientific article

Determinants of GBP recruitment to Toxoplasma gondii vacuoles and the parasitic factors that control it

scientific article

Different capacities of carp leukocytes to encounter nitric oxide-mediated stress: a role for the intracellular reduced glutathione pool.

scientific article published in June 2003

Differential expression and haplotypic variation of two interleukin-1beta genes in the common carp (Cyprinus carpio L.).

scientific article published in April 2003

Exposing Toxoplasma gondii hiding inside the vacuole: a role for GBPs, autophagy and host cell death.

scientific article

Genome-wide screens identify Toxoplasma gondii determinants of parasite fitness in IFNγ-activated murine macrophages

scientific article published on 16 October 2020

Identification of a Master Regulator of Differentiation in Toxoplasma

scientific article published on 16 January 2020

Identification of three novel Toxoplasma gondii rhoptry proteins

scientific article published on 24 September 2013

Incorporating alternative splicing and mRNA editing into the genetic analysis of complex traits.

scientific article

Macrophage Activation and Polarization: Nomenclature and Experimental Guidelines

scholarly article by Peter J. Murray et al published August 2014 in Immunity

Macrophage activation and polarization: nomenclature and experimental guidelines

scientific article (publication date: 17 July 2014)

Major histocompatibility genes in cyprinid fishes: theory and practice

scientific article published on 01 December 1998

Molecular and functional characterization of carp TNF: a link between TNF polymorphism and trypanotolerance?

scientific article published in January 2003

Naïve CD8 T cell IFNγ responses to a vacuolar antigen are regulated by an inflammasome-independent NLRP3 pathway and Toxoplasma gondii ROP5

scientific article published on 27 August 2020

Ontogeny of the common carp (Cyprinus carpio L.) innate immune system

scientific article published on 06 September 2005

Strain-specific activation of the NF-kappaB pathway by GRA15, a novel Toxoplasma gondii dense granule protein.

scientific article

Structure of the Toxoplasma gondii ROP18 Kinase Domain Reveals a Second Ligand Binding Pocket Required for Acute Virulence

scientific article

The GRA17 Parasitophorous Vacuole Membrane Permeability Pore Contributes to Bradyzoite Viability

scientific article published on 12 September 2019

The Toxoplasma Dense Granule Proteins GRA17 and GRA23 Mediate the Movement of Small Molecules between the Host and the Parasitophorous Vacuole.

scientific article published on May 2015

The genetic basis for individual differences in mRNA splicing and APOBEC1 editing activity in murine macrophages.

scientific article

The human immune response to Toxoplasma: Autophagy versus cell death.

scientific article

The rhoptry proteins ROP18 and ROP5 mediate Toxoplasma gondii evasion of the murine, but not the human, interferon-gamma response.

scientific article

Toxoplasma GRA15 Activates the NF-κB Pathway through Interactions with TNF Receptor-Associated Factors

scientific article published on 16 July 2019

Toxoplasma GRA15 limits parasite growth in IFNγ-activated fibroblasts through TRAF ubiquitin ligases

scientific article published on 15 April 2020

Toxoplasma and Plasmodium protein kinases: Roles in invasion and host cell remodelling

scientific article published on December 4, 2011

Toxoplasma co-opts host gene expression by injection of a polymorphic kinase homologue

scientific article published on 20 December 2006

Toxoplasma gondii clonal strains all inhibit STAT1 transcriptional activity but polymorphic effectors differentially modulate IFNγ induced gene expression and STAT1 phosphorylation

scientific article

Toxoplasma gondii effectors are master regulators of the inflammatory response

scientific article published on September 3, 2011

Toxoplasma gondii rhoptry 16 kinase promotes host resistance to oral infection and intestinal inflammation only in the context of the dense granule protein GRA15.

scientific article published on April 2013

Toxoplasma gondii superinfection and virulence during secondary infection correlate with the exact ROP5/ROP18 allelic combination.

scientific article

Toxoplasma gondii: inconsistent dissemination patterns following oral infection in mice.

scientific article published on 25 January 2007

Toxoplasma polymorphic effectors determine macrophage polarization and intestinal inflammation.

scientific article

Toxoplasma  GRA15 and GRA24 are important activators of the host innate immune response in the absence of TLR11

scientific article published on 26 May 2020

Transcriptional analysis of murine macrophages infected with different Toxoplasma strains identifies novel regulation of host signaling pathways

scientific article

Transcriptional and Linkage Analyses Identify Loci that Mediate the Differential Macrophage Response to Inflammatory Stimuli and Infection

scientific article published on 28 October 2015

miR-146a and miR-155 delineate a MicroRNA fingerprint associated with Toxoplasma persistence in the host brain.

scientific article published on 27 February 2014