List of works by Christoph Kleinschnitz

18F-flutemetamol positron emission tomography in cardiac amyloidosis

scientific article published on 06 October 2020

4-Aminopyridine ameliorates mobility but not disease course in an animal model of multiple sclerosis

article

A Preliminary Study on Machine Learning-Based Evaluation of Static and Dynamic FET-PET for the Detection of Pseudoprogression in Patients with IDH-Wildtype Glioblastoma

scientific article published on 22 October 2020

A combined pre-clinical meta-analysis and randomized confirmatory trial approach to improve data validity for therapeutic target validation

scientific article

A diseasome cluster-based drug repurposing of soluble guanylate cyclase activators from smooth muscle relaxation to direct neuroprotection

scientific article published on 5 February 2018

A fatal case of daclizumab-induced liver failure in a patient with MS

scientific article published on 21 January 2019

A modified double injection model of cisterna magna for the study of delayed cerebral vasospasm following subarachnoid hemorrhage in rats

scientific article published on 29 November 2012

A systems biology approach to cGMP suggests a prominent role for sGC in stroke: Validation by mechanism-based activation of apo-sGC in non-steal dosing coveys neuroprotection and increased survival

scientific article

ACKR3 regulates platelet activation and ischemia-reperfusion tissue injury

scientific article published on 05 April 2022

ACTR-49. PriCoTTF: A PHASE I/II TRIAL OF TUMOR TREATING FIELDS PRIOR AND CONCOMITANT TO RADIOTHERAPY IN NEWLY DIAGNOSED GLIOBLASTOMA

scientific article published on 5 November 2018

ADAMTS13-mediated thrombolysis of t-PA-resistant occlusions in ischemic stroke in mice.

scientific article

Absence of Regulatory T Cells Causes Phenotypic and Functional Switch in Murine Peritoneal Macrophages

scientific article published on 31 October 2018

Accidental Thrombolysis in a Stroke Patient Receiving Apixaban

scientific article published on 21 May 2015

Activation and functional modulation of satellite glial cells by oxaliplatin lead to hyperexcitability of sensory neurons in vitro

scientific article published on 07 May 2020

Acute tetraparesis secondary to bilateral precentral gyral cerebral ischemia: a case report

scientific article published on 8 March 2013

Adherence to oral anticoagulant therapy in secondary stroke prevention - impact of the novel oral anticoagulants

scientific article

Advances in Multiple Sclerosis 2017.

scientific article

Alemtuzumab as rescue therapy in a cohort of 50 relapsing-remitting MS patients with breakthrough disease on fingolimod: a multi-center observational study.

scientific article

Alleviation of secondary brain injury, posttraumatic inflammation, and brain edema formation by inhibition of factor XIIa

scientific article published on 20 February 2017

An experimental protocol for mimicking pathomechanisms of traumatic brain injury in mice

scientific article published on 2 February 2012

Animal models of ischemic stroke and their application in clinical research

scientific article published on 02 July 2015

Animal models of ischemic stroke and their impact on drug discovery

scientific article published on 04 February 2019

Anti-CD52 antibody treatment depletes B cell aggregates in the central nervous system in a mouse model of multiple sclerosis

article

Antithrombotic potential of blockers of store-operated calcium channels in platelets.

scientific article

Apheresis therapies for NMOSD attacks: A retrospective study of 207 therapeutic interventions

Assessment of nerve degeneration by gadofluorine M-enhanced magnetic resonance imaging

scientific article published in March 2005

Autoantibodies against central nervous system antigens in a subset of B cell-dominant multiple sclerosis patients

scientific article published on 18 August 2020

Automated ASPECT rating: comparison between the Frontier ASPECT Score software and the Brainomix software

scientific article published on 15 September 2018

B cells do not have a major pathophysiologic role in acute ischemic stroke in mice.

scientific article published on 2 June 2017

B1 cells are unaffected by immune modulatory treatment in remitting-relapsing multiple sclerosis patients.

scientific article published on 24 April 2014

Binding of von Willebrand factor to collagen and glycoprotein Ibalpha, but not to glycoprotein IIb/IIIa, contributes to ischemic stroke in mice--brief report

scientific article published on 8 July 2010

Blockade of bradykinin receptor B1 but not bradykinin receptor B2 provides protection from cerebral infarction and brain edema

scientific article published on 6 November 2008

Blockade of the kinin receptor B1 protects from autoimmune CNS disease by reducing leukocyte trafficking.

scientific article published on 8 January 2011

Blocking of bradykinin receptor B1 protects from focal closed head injury in mice by reducing axonal damage and astroglia activation.

scientific article

Blocking of plasma kallikrein ameliorates stroke by reducing thromboinflammation

scientific article published on 13 March 2015

Blocking of platelet glycoprotein receptor Ib reduces "thrombo-inflammation" in mice with acute ischemic stroke.

scientific article published on 21 January 2017

Blocking of platelets or intrinsic coagulation pathway-driven thrombosis does not prevent cerebral infarctions induced by photothrombosis

scientific article

Blocking of α4 integrin does not protect from acute ischemic stroke in mice.

scientific article published on 17 April 2014

Blood coagulation factor XII drives adaptive immunity during neuroinflammation via CD87-mediated modulation of dendritic cells

scientific article published on 18 May 2016

Blood coagulation factor XII--a neglected player in stroke pathophysiology

scientific article published on 10 September 2011

Bone marrow-derived myeloid progenitors in the leptomeninges of adult mice

scientific article published on 03 December 2020

Bone marrow-derived myeloid progenitors in the leptomeninges of adult mice

scientific article published in 2020

C1-Inhibitor protects from focal brain trauma in a cortical cryolesion mice model by reducing thrombo-inflammation

scientific article

C1-inhibitor protects from brain ischemia-reperfusion injury by combined antiinflammatory and antithrombotic mechanisms.

scientific article published on 28 June 2012

CD28 superagonist-mediated boost of regulatory T cells increases thrombo-inflammation and ischemic neurodegeneration during the acute phase of experimental stroke.

scientific article published on 15 October 2014

CEACAM1 mediates B cell aggregation in central nervous system autoimmunity.

scientific article published on 20 July 2016

CGRP antibody therapy in patients with drug resistant migraine and chronic daily headache: a real-world experience

scientific article published on 20 September 2021

CIDP, myasthenia gravis, and membranous glomerulonephritis - three autoimmune disorders in one patient: a case report

scientific article published on 14 August 2018

CK2β regulates thrombopoiesis and Ca2+-triggered platelet activation in arterial thrombosis.

scientific article published on 19 September 2017

COU254, a specific 3-carboxamide-coumarin inhibitor of coagulation factor XII, does not protect mice from acute ischemic stroke

scientific article published on 15 February 2010

Calcium-dependent blood-brain barrier breakdown by NOX5 limits postreperfusion benefit in stroke

scholarly article by Ana I Casas et al published 18 March 2019 in Journal of Clinical Investigation

Calcium-dependent membrane association sensitizes soluble guanylyl cyclase to nitric oxide

scientific article published in April 2002

Case-control study of platelet glycoprotein receptor Ib and IIb/IIIa expression in patients with acute and chronic cerebrovascular disease.

scientific article

Categorization of multiple sclerosis relapse subtypes by B cell profiling in the blood

scientific article

Cerebral gray matter changes in persistent postural perceptual dizziness

scientific article published on 16 October 2017

Cerebrospinal fluid JC virus antibody index for diagnosis of natalizumab-associated progressive multifocal leukoencephalopathy

scientific article

Cerebrospinal fluid parameters of B cell-related activity in patients with active disease during natalizumab therapy

scientific article published on 23 October 2012

Characterization of Peripheral Immune Cell Subsets in Patients with Acute and Chronic Cerebrovascular Disease: A Case-Control Study

scientific article

Cisplatin alters the function and expression of N-type voltage-gated calcium channels in the absence of morphological damage of sensory neurons

scientific article published in January 2017

Clinical Implication of Dosimetry of Computed Tomography- and Fluoroscopy-Guided Intrathecal Therapy With Nusinersen in Adult Patients With Spinal Muscular Atrophy

scientific article published on 05 November 2019

Coagulation Testing in Acute Ischemic Stroke Patients Taking Non-Vitamin K Antagonist Oral Anticoagulants

scientific article

Coagulation factors and multiple sclerosis : Key factors in the pathogenesis?

scientific article published on 5 February 2018

Combating innate inflammation: a new paradigm for acute treatment of stroke? ⬇️

scientific article published on October 1, 2010

Combined [(18)F]DPA-714 micro-positron emission tomography and autoradiography imaging of microglia activation after closed head injury in mice

scientific article published on 07 June 2016

Comparing Plasma Exchange to Escalated Methyl Prednisolone in Refractory Multiple Sclerosis Relapses

scientific article published on 22 December 2019

Comparison of L-Methyl-11C-Methionine PET With Magnetic Resonance Spectroscopy in Detecting Newly Diagnosed Glioma

scientific article published on 01 June 2019

Compromised Hippocampal Neuroplasticity in the Interferon-α and Toll-like Receptor-3 Activation-Induced Mouse Depression Model

scientific article published on 05 June 2020

Computer aided diagnosis for ASPECT rating: initial experiences with the Frontier ASPECT Score software

scientific article published on 24 April 2019

Con: Regulatory T cells are protective in ischemic stroke

scientific article published on 02 July 2013

Contrasting disease patterns in seropositive and seronegative neuromyelitis optica: A multicentre study of 175 patients

scientific article published in 2012

Corneal Confocal Microscopy Demonstrates Corneal Nerve Loss in Patients With Trigeminal Neuralgia

scientific article published on 24 July 2020

Correction: Two pore domain potassium channels in cerebral ischemia: a focus on K2P9.1 (TASK3, KCNK9).

scientific article

Corrigendum to 'Should IV Thrombolysis be given in Patients with Suspected Ischemic Stroke but Unknown Symptom Onset and Without Diffusion-Weighted Imaging Lesion? - Results of a Case-Control Study' [Journal of Stroke and Cerebrovascular Diseases, V

scientific article published on 12 March 2020

Cytokine profile of iron-laden macrophages: implications for cellular magnetic resonance imaging

scientific article published on 27 December 2005

Dabigatran Etexilate Reduces Thrombin-Induced Inflammation and Thrombus Formation in Experimental Ischemic Stroke.

scientific article

Danger signals in stroke.

scientific article published on 22 July 2015

Deactivation of ATP-Binding Cassette Transporters ABCB1 and ABCC1 Does Not Influence Post-ischemic Neurological Deficits, Secondary Neurodegeneration and Neurogenesis, but Induces Subtle Microglial Morphological Changes

scientific article published on 12 September 2019

Decreasing longitudinal use of glucocorticosteroids in multiple sclerosis

scientific article published on 24 July 2018

Deficiency of bradykinin receptor B2 is not detrimental in experimental stroke.

scientific article

Deficiency of the negative immune regulator B7-H1 enhances inflammation and neuropathic pain after chronic constriction injury of mouse sciatic nerve.

scientific article published on 4 January 2010

Deficiency of vasodilator-stimulated phosphoprotein (VASP) increases blood-brain-barrier damage and edema formation after ischemic stroke in mice

scientific article

Deficiency of von Willebrand factor protects mice from ischemic stroke

scientific article

Depletion of CD11c+ Cells Does Not Influence Outcomes in Mice Subjected to Transient Middle Cerebral Artery Occlusion

scientific article published on 31 October 2017

Description of a Novel Phosphodiesterase (PDE)-3 Inhibitor Protecting Mice From Ischemic Stroke Independent From Platelet Function

scientific article published on 01 February 2019

Detection of early infarction signs with machine learning-based diagnosis by means of the Alberta Stroke Program Early CT score (ASPECTS) in the clinical routine

scientific article published on 31 July 2018

Differential effects of FTY720 on the B cell compartment in a mouse model of multiple sclerosis.

scientific article

Differential impact of pure glyphosate and glyphosate-based herbicide in a model of peripheral nervous system myelination

scientific article published on 16 November 2018

Dimethyl fumarate accelerates peripheral nerve regeneration via activation of the anti-inflammatory and cytoprotective Nrf2/HO-1 signaling pathway

scientific article published on 20 January 2017

Dose-Dependent Microglial and Astrocytic Responses Associated With Post-ischemic Neuroprotection After Lipopolysaccharide-Induced Sepsis-Like State in Mice

scientific article published on 12 February 2020

Downregulation of transforming growth factor-beta2 facilitates inflammation in the central nervous system by reciprocal astrocyte/microglia interactions

scientific article published in January 2007

Early Clinical and Radiological Course, Management, and Outcome of Intracerebral Hemorrhage Related to New Oral Anticoagulants

scientific article published on 14 December 2015

Early detrimental T-cell effects in experimental cerebral ischemia are neither related to adaptive immunity nor thrombus formation

scientific article published on 9 March 2010

Early microvascular dysfunction in cerebral small vessel disease is not detectable on 3.0 Tesla magnetic resonance imaging: a longitudinal study in spontaneously hypertensive stroke-prone rats.

scientific article published on 25 June 2013

Editorial: Mechanisms of neuroinflammation and inflammatory neurodegeneration in acute brain injury

scientific article published on 5 August 2015

Effective treatment of adjuvant arthritis with a stimulatory CD28-specific monoclonal antibody.

scientific article published in January 2006

Effectiveness of Endovascular Recanalization Treatment for M2 Segment Occlusion: Comparison Between Intracranial ICA, M1, and M2 Segment Thrombectomy

scientific article published on 24 December 2018

Effects of Long-Term Temozolomide Treatment on Glioblastoma and Astrocytoma WHO Grade 4 Stem-like Cells

scientific article published on 08 May 2022

Effects of glatiramer acetate in a spontaneous model of autoimmune neuroinflammation

scientific article published on 09 May 2014

Efficacy and Safety of Platelet Glycoprotein Receptor Blockade in Aged and Comorbid Mice With Acute Experimental Stroke.

scientific article published on 20 October 2015

Efficacy and safety of alemtuzumab versus fingolimod in RRMS after natalizumab cessation

scientific article published on 16 November 2018

Elastase inhibitor agaphelin protects from acute ischemic stroke in mice by reducing thrombosis, blood-brain barrier damage, and inflammation

scientific article published on 02 January 2021

Endothelial TWIK-related potassium channel-1 (TREK1) regulates immune-cell trafficking into the CNS.

scientific article

Erenumab in highly therapy-refractory migraine patients: First German real-world evidence

scientific article published on 03 July 2020

Experience in Multiple Sclerosis Patients with COVID-19 and Disease-Modifying Therapies: A Review of 873 Published Cases

scientific article published on 16 December 2020

Expression of K2P5.1 potassium channels on CD4+ T lymphocytes correlates with disease activity in rheumatoid arthritis patients

scientific article published on 11 February 2011

FTY720 ameliorates acute ischemic stroke in mice by reducing thrombo-inflammation but not by direct neuroprotection

scientific article published on 12 September 2013

FTY720 does not protect from traumatic brain injury in mice despite reducing posttraumatic inflammation

scientific article published on 22 July 2014

Factor XIIa inhibitor recombinant human albumin Infestin-4 abolishes occlusive arterial thrombus formation without affecting bleeding

scientific article published on 22 March 2010

Failed, interrupted and inconclusive trials on relapsing multiple sclerosis treatment: update 2010-2015.

scientific article published on 8 April 2016

Fatal atypical reversible posterior leukoencephalopathy syndrome: a case report

scientific article published on 10 January 2013

Feasibility and diagnostic accuracy of point-of-care handheld echocardiography in acute ischemic stroke patients - a pilot study

scientific article published on 11 August 2017

Feasibility and safety of intrathecal treatment with nusinersen in adult patients with spinal muscular atrophy

scholarly article by Benjamin Stolte et al published 2018 in Therapeutic advances in neurological disorders

Feasibility of intra-arterial chemotherapy for retinoblastoma: experiences in a large single center cohort study

scientific article published on 14 January 2019

Fingolimod (FTY720) Reduces Cortical Infarction and Neurological Deficits During Ischemic Stroke Through Potential Maintenance of Microvascular Patency.

scientific article

Fingolimod (FTY720-P) Does Not Stabilize the Blood-Brain Barrier under Inflammatory Conditions in an in Vitro Model

scientific article

Focal brain trauma in the cryogenic lesion model in mice

scientific article

Focal cerebral ischemia

scientific article published on 01 January 2012

FoxP3 deficiency causes no inflammation or neurodegeneration in the murine brain

scientific article published on 18 March 2020

Fullerenols and glucosamine fullerenes reduce infarct volume and cerebral inflammation after ischemic stroke in normotensive and hypertensive rats

scientific article published on 24 January 2015

Functional Relevance of the Anaphylatoxin Receptor C3aR for Platelet Function and Arterial Thrombus Formation Marks an Intersection Point Between Innate Immunity and Thrombosis

scientific article published on 01 October 2018

Functional role of regulatory lymphocytes in stroke: facts and controversies

scientific article published on 19 March 2015

Gain-of-function STAT1 mutations are associated with intracranial aneurysms.

scientific article published on February 2017

Genotype-phenotype correlation in a novel ABHD12 mutation underlying PHARC syndrome

scientific article published on 19 February 2020

Glatiramer acetate attenuates pro-inflammatory T cell responses but does not directly protect neurons from inflammatory cell death

scientific article

Glatiramer acetate does not protect from acute ischemic stroke in mice.

scientific article published on 27 February 2014

Glucocorticoid insensitivity at the hypoxic blood-brain barrier can be reversed by inhibition of the proteasome.

scientific article published on 17 February 2011

Glyphosate-based herbicide: a risk factor for demyelinating conditions of the peripheral nervous system?

scientific article published on 01 December 2019

Gray platelet syndrome and defective thrombo-inflammation in Nbeal2-deficient mice.

scientific article

Gut bacterial microbiota in patients with myasthenia gravis: results from the MYBIOM study

scientific article published on 11 August 2021

Gute Ernährung reduziert MS-Symptome

scientific article published on 01 October 2018

HOUT-30. TUMOR TREATING FIELDS (TTFIELDS) IN COMBINATION WITH LOMUSTINE (CCNU) AND TEMOZOLOMIDE (TMZ) IN PATIENTS WITH NEWLY DIAGNOSED GLIOBLASTOMA (GBM)

scientific article published on 5 November 2018

Health Related Quality of Life in Patients with Untreated Cavernous Malformations of the Central Nervous System- Quality of Life in patients with untreated CCM

scientific article published on 22 September 2020

Health outcome of older hospitalized patients in internal medicine environments evaluated by Identification of Seniors at Risk (ISAR) screening and geriatric assessment

scientific article published on 14 August 2019

Hemorrhage from cerebral cavernous malformations: The role of associated developmental venous anomalies

scientific article published on 08 June 2020

Homozygous Smpd1 deficiency aggravates brain ischemia/ reperfusion injury by mechanisms involving polymorphonuclear neutrophils, whereas heterozygous Smpd1 deficiency protects against mild focal cerebral ischemia

scientific article published on 14 October 2020

How is the formation of microthrombi after traumatic brain injury linked to inflammation?

scientific article published on 31 October 2018

Hybrid 11C-MET PET/MRI Combined With "Machine Learning" in Glioma Diagnosis According to the Revised Glioma WHO Classification 2016

scientific article published on 01 March 2019

Hypercholesterolemia induced cerebral small vessel disease

scientific article published on 10 August 2017

Hypocaloric Diet Initiated Post-Ischemia Provides Long-Term Neuroprotection and Promotes Peri-Infarct Brain Remodeling by Regulating Metabolic and Survival-Promoting Proteins

scientific article published on 17 November 2020

Identification of two-pore domain potassium channels as potent modulators of osmotic volume regulation in human T lymphocytes

scientific article published on 3 October 2012

Immune mechanisms of stroke.

scientific article published on June 2012

Immunohistochemical Analysis of Cerebral Thrombi Retrieved by Mechanical Thrombectomy from Patients with Acute Ischemic Stroke.

scientific article published on 26 February 2016

Immunology of stroke: from animal models to clinical trials

scientific article published on 21 February 2019

Immunotherapeutic approaches in MS: update on pathophysiology and emerging agents or strategies 2006.

scientific article published on March 2007

Immunotherapies in neuromyelitis optica spectrum disorder: efficacy and predictors of response

scientific article published on June 2017

Immunotherapy of experimental and human stroke with agents approved for multiple sclerosis: a systematic review.

scientific article published on 20 April 2018

Impaired alpha(IIb)beta(3) integrin activation and shear-dependent thrombus formation in mice lacking phospholipase D1.

scientific article published on 5 January 2010

Impaired wound healing in a migraine patient as a possible side effect of calcitonin gene-related peptide receptor antibody treatment: A case report

scientific article published on 14 June 2020

Implications of COVID-19 Outbreak on Immune Therapies in Multiple Sclerosis Patients-Lessons Learned From SARS and MERS

scientific article published on 12 May 2020

Implications of polymorphonuclear neutrophils for ischemic stroke and intracerebral hemorrhage: Predictive value, pathophysiological consequences and utility as therapeutic target

scientific article published on 24 April 2018

In vivo detection of developing vessel occlusion in photothrombotic ischemic brain lesions in the rat by iron particle enhanced MRI.

scientific article

In vivo imaging of stepwise vessel occlusion in cerebral photothrombosis of mice by 19F MRI.

scientific article

Increases survival by apo-sGC activation via post-stroke blood brain barrier stabilisation and anti-inflammation.

scientific article published on 29 August 2013

Induction of granulocyte colony-stimulating factor mRNA by focal cerebral ischemia and cortical spreading depression.

scientific article published in November 2004

Influence of female sex and fertile age on neuromyelitis optica spectrum disorders

scientific article

Inhibition of bradykinin receptor B1 protects mice from focal brain injury by reducing blood-brain barrier leakage and inflammation

scientific article

Interferon Beta-1a (AVONEX®) as a Treatment Option for Untreated Patients with Multiple Sclerosis (AXIOM): A Prospective, Observational Study

scientific article published on 6 July 2015

Interleukin-18 does not influence infarct volume or functional outcome in the early stage after transient focal brain ischemia in mice

scientific article

Intracranial Aneurysms in Sickle Cell Disease

scientific article published on 01 January 2019

Intrathecal Resiniferatoxin Modulates TRPV1 in DRG Neurons and Reduces TNF-Induced Pain-Related Behavior

scientific article published on 2 August 2017

Intravenous thrombolysis in a stroke patient receiving rivaroxaban

scientific article published on 26 October 2013

Intravital imaging in spontaneously hypertensive stroke-prone rats-a pilot study

scientific article

Iron-enhanced MRI in ischemic stroke: intravascular trapping versus cellular inflammation

scientific article published on 15 March 2007

Is Histologic Thrombus Composition in Acute Stroke Linked to Stroke Etiology or to Interventional Parameters?

scientific article published on 19 March 2020

Is Small Fiber Neuropathy Induced by Gadolin clóset ium-Based Contrast Agents?

scientific article published on 24 June 2020 clóset

Ischaemic stroke: a thrombo-inflammatory disease?

scientific article published on 18 July 2011

Ischemia-induced cell depolarization: does the hyperpolarization-activated cation channel HCN2 affect the outcome after stroke in mice?

scientific article published on 27 December 2013

Ischemic stroke and traumatic brain injury: the role of the kallikrein-kinin system.

scientific article published on 27 December 2012

Kininogen deficiency protects from ischemic neurodegeneration in mice by reducing thrombosis, blood-brain barrier damage, and inflammation

scientific article published on 30 August 2012

L-selectin is a possible biomarker for individual PML risk in natalizumab-treated MS patients

scientific article published on 7 August 2013

Laboratory biomarkers of delayed cerebral ischemia after subarachnoid hemorrhage: a systematic review

article

Lesion-associated expression of transforming growth factor-beta-2 in the rat nervous system: evidence for down-regulating the phagocytic activity of microglia and macrophages

scientific article published in January 2004

Letter by De Meyer et al regarding article "High von Willebrand factor levels increase the risk of stroke: the Rotterdam study"

scientific article published on 03 February 2011

Light Sheet Microscopy Using FITC-Albumin Followed by Immunohistochemistry of the Same Rehydrated Brains Reveals Ischemic Brain Injury and Early Microvascular Remodeling

scientific article published in 2021

Lipopolysaccharide-induced sepsis-like state compromises post-ischemic neurological recovery, brain tissue survival and remodeling via mechanisms involving microvascular thrombosis and brain T cell infiltration

scientific article published on 22 October 2020

Long-term management of multiple sclerosis patients treated with cladribine tablets: an expert opinion

scientific article published on 13 July 2020

Longitudinal heterogeneity in glioblastoma: moving targets in recurrent versus primary tumors

scientific article published on 20 March 2019

Loss of Orai2-Mediated Capacitative Ca2+ Entry Is Neuroprotective in Acute Ischemic Stroke

scientific article published on 25 September 2019

Lysophosphatidic acid propagates post-injury Schwann cell dedifferentiation through LPA1 signaling

scientific article

Megakaryocyte-specific RhoA deficiency causes macrothrombocytopenia and defective platelet activation in hemostasis and thrombosis.

scientific article

Mesenchymal Stromal Cell-Derived Small Extracellular Vesicles Induce Ischemic Neuroprotection by Modulating Leukocytes and Specifically Neutrophils

scientific article published on 21 April 2020

Microelectrode Guided Implantation of Electrodes into the Subthalamic Nucleus of Rats for Long-term Deep Brain Stimulation.

scientific article published on 2 October 2015

Minimal Clinically Important Differences in Functional Motor Scores in Adult Patients with Spinal Muscular Atrophy

scientific article published on 11 August 2020

Modeling Vascular Risk Factors for the Development of Ischemic Stroke Therapies

scientific article published on 01 May 2019

Moderate Protein Restriction Protects Against Focal Cerebral Ischemia in Mice by Mechanisms Involving Anti-inflammatory and Anti-oxidant Responses

scientific article published on 01 July 2019

Molecular mechanisms of thrombus formation in ischemic stroke: novel insights and targets for treatment

scientific article published on August 2008

Multifocal motor neuropathy: update on clinical characteristics, pathophysiological concepts and therapeutic options

scientific article published on 11 February 2010

Multimodal outcome assessment after surgery for brainstem cavernous malformations

scientific article published on 16 October 2020

Multiple sclerosis therapy: an update on recently finished trials

scientific article published on 15 November 2007

Munc13-4-mediated secretion is essential for infarct progression but not intracranial hemostasis in acute stroke.

scientific article

NIMG-32. COMPARISON OF L-METHYL-11C-METHIONINE POSITRON EMISSION TOMOGRAPHY WITH MAGNETIC RESONANCE SPECTROSCOPY IN DETECTING NEWLY DIAGNOSED GLIOMA

NK cell markers predict the efficacy of IV immunoglobulins in CIDP

scientific article published on 02 October 2020

NOS knockout or inhibition but not disrupting PSD-95-NOS interaction protect against ischemic brain damage.

scientific article published on 28 June 2016

NOX4 is a Janus-faced reactive oxygen species generating NADPH oxidase

scientific article published on 01 June 2012

NOX4 is an early initiator of neuropathic pain

scientific article published on 14 November 2016

NOX4-dependent neuronal autotoxicity and BBB breakdown explain the superior sensitivity of the brain to ischemic damage.

scientific article

Natalizumab exerts a suppressive effect on surrogates of B cell function in blood and CSF.

scientific article

Neurofilament Heavy Chain and Tau Protein Are Not Elevated in Cerebrospinal Fluid of Adult Patients with Spinal Muscular Atrophy during Loading with Nusinersen ⬇️

scientific article published on 30 October 2019

Neurological Manifestations of COVID-19 Feature T Cell Exhaustion and Dedifferentiated Monocytes in Cerebrospinal Fluid

scientific article published on 23 December 2020

Neuromyelitis optica: Evaluation of 871 attacks and 1,153 treatment courses

scientific article

Neuroprotection Induced by Energy and Protein-Energy Undernutrition Is Phase-Dependent After Focal Cerebral Ischemia in Mice

scientific article published on 18 March 2019

Neuroprotection after stroke by targeting NOX4 as a source of oxidative stress

scientific article

Neuroprotection for ischaemic stroke: translation from the bench to the bedside

scientific article published on 06 March 2012

Neuroprotection for stroke: current status and future perspectives

scientific article

Neurovascular pathophysiology in cerebral ischemia, dementia and the ageing brain - current trends in basic, translational and clinical research

scientific article published on 10 August 2012

Next-generation antithrombotics in ischemic stroke: preclinical perspective on 'bleeding-free antithrombosis'

scientific article

NfL predicts relapse-free progression in a longitudinal multiple sclerosis cohort study

scientific article published on 24 September 2021

No risk, no benefit: still true for antithrombotic stroke treatments?

scientific article

Non-Vitamin K Oral Anticoagulants in Stroke Patients: Practical Issues

scientific article

Nusinersen in adults with 5q spinal muscular atrophy: a non-interventional, multicentre, observational cohort study

scientific article published on 18 March 2020

Olfactory function as an independent prognostic factor in glioblastoma

scientific article published on 12 December 2019

Only severe thrombocytopenia results in bleeding and defective thrombus formation in mice.

scientific article

Orai1 (CRACM1) is the platelet SOC channel and essential for pathological thrombus formation

scientific article published on 2 October 2008

Outcome of experimental stroke in C57Bl/6 and Sv/129 mice assessed by multimodal ultra-high field MRI.

scientific article published on 15 March 2010

Overcoming trivialization: The neuroimmune response after acute central nervous system injury

scientific article published on 31 January 2019

Oxaliplatin Modulates the Characteristics of Voltage-Gated Calcium Channels and Action Potentials in Small Dorsal Root Ganglion Neurons of Rats.

scientific article published on 30 March 2018

PDK1 Determines Collagen-Dependent Platelet Ca2+ Signaling and Is Critical to Development of Ischemic Stroke In Vivo

scientific article published on 23 June 2016

PI3KC2β inactivation stabilizes VE-cadherin junctions and preserves vascular integrity

scientific article published on 20 April 2021

PML risk stratification using anti-JCV antibody index and L-selectin.

scientific article published on 2 October 2015

Phospholipase D1 mediates lymphocyte adhesion and migration in experimental autoimmune encephalomyelitis

scientific article published on 5 June 2014

Plasma kallikrein modulates immune cell trafficking during neuroinflammation via PAR2 and bradykinin release

scientific article published on 17 December 2018

Platelet depletion does not alter long-term functional outcome after cerebral ischaemia in mice

scientific article published in 2022

Platelet derived FasL contributes to apoptosis in stroke

scientific article published on 25 August 2016

Platelet-derived VWF is not essential for normal thrombosis and hemostasis but fosters ischemic stroke injury in mice.

scientific article published on 24 July 2015

Platelets and vascular inflammation of the brain.

scientific article published on 19 May 2015

Platelets induce apoptosis via membrane-bound FasL.

scientific article

Platinum-Based Drugs Cause Mitochondrial Dysfunction in Cultured Dorsal Root Ganglion Neurons

scientific article published on 16 November 2020

Polarity-specific modulation of pain processing by transcranial direct current stimulation - a blinded longitudinal fMRI study

article

Post-stroke inhibition of induced NADPH oxidase type 4 prevents oxidative stress and neurodegeneration

scientific article

Post-treatment Antiplatelet Therapy Reduces Risk for Delayed Cerebral Ischemia due to Aneurysmal Subarachnoid Hemorrhage

scientific article published on 01 December 2019

Postacute Delivery of GABA α5 Antagonist Promotes Postischemic Neurological Recovery and Peri-infarct Brain Remodeling

scientific article published on 01 October 2018

Prescription frequency and predictors for the use of novel direct oral anticoagulants for secondary stroke prevention in the first year after their marketing in Europe--a multicentric evaluation

scientific article published on 15 May 2014

Pretreatment anti-thyroid autoantibodies indicate increased risk for thyroid autoimmunity secondary to alemtuzumab: A prospective cohort study

scientific article published on 29 July 2019

Pretreatment with rivaroxaban attenuates stroke severity in rats by a dual antithrombotic and anti-inflammatory mechanism.

scientific article published on 22 October 2015

Prevalence and determinants of systolic and diastolic cardiac dysfunction and heart failure in acute ischemic stroke patients: The SICFAIL study

scientific article published on 22 December 2020

Prevalence of hereditary transthyretin amyloid polyneuropathy in idiopathic progressive neuropathy in conurban areas

scientific article published on 18 September 2019

Protective potential of dimethyl fumarate in a mouse model of thalamocortical demyelination

scientific article published on 09 May 2018

Prothrombin and factor X are elevated in multiple sclerosis patients.

scientific article published on 24 October 2016

Radiation exposure of image-guided intrathecal administration of nusinersen to adult patients with spinal muscular atrophy

scientific article published on 14 March 2019

Recent clinical trials and future therapies

scientific article published on December 2008

Reduced ADAMTS13 levels in patients with acute and chronic cerebrovascular disease

scientific article

Redundant functions of phospholipases D1 and D2 in platelet α-granule release

scientific article published on 01 November 2012

Regorafenib in patients with recurrent high-grade astrocytoma

scientific article published on 28 February 2019

Regulation of blood coagulation factors XI and XII in patients with acute and chronic cerebrovascular disease: a case-control study.

scientific article published on 21 November 2014

Regulatory T Cells in Post-stroke Immune Homeostasis

scientific article published on 31 March 2016

Regulatory T cells are strong promoters of acute ischemic stroke in mice by inducing dysfunction of the cerebral microvasculature

scientific article published on 15 November 2012

Relative health-related quality of life after treatment of unruptured intracranial aneurysms: long-term outcomes and influencing factors

article

Report on the 1st scientific meeting of the "Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie" (NEUROWIND e.V.) held in Mittenwalde/Motzen, Germany, Oct. 30th - Nov. 1st, 2009.

scientific article published on 31 March 2010

Report on the 2nd scientific meeting of the "Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie" (NEUROWIND e.V.) held in Motzen, Germany, Oct. 29'th - Oct. 31'st, 2010.

scientific article published on April 2011

Report on the 3'rd scientific meeting of the "Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie" (NEUROWIND e.V.) held in Motzen, Germany, Nov. 4'th - Nov. 6'th, 2011.

scientific article published on 23 February 2012

Report on the 4'th scientific meeting of the "Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie" (NEUROWIND e.V.) held in Motzen, Germany, Nov. 2'nd - Nov. 4'th, 2012

scientific article published on 22 November 2012

Report on the 5'th scientific meeting of the "Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie" (NEUROWIND e.V.) held in Motzen, Germany, Oct. 25th - Oct. 27th, 2013.

scientific article

Report on the 6th scientific meeting of the "Verein zur Förderung des Wissenschaftlichen Nachwuchses in der Neurologie" (NEUROWIND e.V.) held in Motzen, Germany, Oct. 31th - Nov. 2nd, 2014.

scientific article published on 13 January 2015

Report on the 7th scientific meeting of the Association for the Advancement of Young Academics in Neurology (NEUROWIND e.V.) held in Motzen, Germany, October 30–November 1, 2015.

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Response to letter regarding article, "blocking of α4 integrin does not protect from acute ischemic stroke in mice".

scientific article published on 24 July 2014

Risk Factors for and Clinical Consequences of Multiple Intracranial Aneurysms: A Systematic Review and Meta-Analysis.

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Rivaroxaban ameliorates disease course in an animal model of multiple sclerosis.

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Rodent models of focal cerebral ischemia: procedural pitfalls and translational problems

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Role of immune responses for extracellular matrix remodeling in the ischemic brain

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Role of polymorphonuclear neutrophils in the reperfused ischemic brain: insights from cell-type-specific immunodepletion and fluorescence microscopy studies

scientific article published on 14 September 2018

Role of the kallikrein-kinin system in traumatic brain injury

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SLAP/SLAP2 prevent excessive platelet (hem)ITAM signaling in thrombosis and ischemic stroke in mice

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STIM2 regulates capacitive Ca2+ entry in neurons and plays a key role in hypoxic neuronal cell death

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Safety and efficacy of prednisone versus placebo in short-term prevention of episodic cluster headache: a multicentre, double-blind, randomised controlled trial

scientific article published on 24 November 2020

Safety of Endovascular Thrombectomy in Patients Receiving Non-Vitamin K Antagonist Oral Anticoagulants

scientific article published on March 2016

Should IV Thrombolysis be given in Patients with Suspected Ischemic Stroke but Unknown Symptom Onset and Without Diffusion-Weighted Imaging Lesion? - Results of a Case-Control Study

scientific article published on 27 November 2019

Simultaneous primary cancer occurrence of melanoma and pulmonary adenocarcinoma in leptomeningeal metastases: a case report

scientific article published on 23 October 2019

Sleep-Disordered Breathing in Hospitalized Geriatric Patients with Mild Dementia and Its Association with Cognition, Emotion and Mobility

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Small extracellular vesicles obtained from hypoxic mesenchymal stromal cells have unique characteristics that promote cerebral angiogenesis, brain remodeling and neurological recovery after focal cerebral ischemia in mice

scientific article published on 08 June 2021

Stimulation of the mesencephalic locomotor region for gait recovery after stroke.

scientific article published on 23 October 2017

Stroke-induced chronic systolic dysfunction driven by sympathetic overactivity.

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Stromal interaction molecules 1 and 2 are key regulators of autoreactive T cell activation in murine autoimmune central nervous system inflammation

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Sustained reperfusion after blockade of glycoprotein-receptor-Ib in focal cerebral ischemia: an MRI study at 17.6 Tesla

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Symptomatology and symptomatic treatment in multiple sclerosis: Results from a nationwide MS registry

scientific article published on 19 September 2018

T cell infiltration after chronic constriction injury of mouse sciatic nerve is associated with interleukin-17 expression.

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TMEM16F-Mediated Platelet Membrane Phospholipid Scrambling Is Critical for Hemostasis and Thrombosis but not Thromboinflammation in Mice-Brief Report.

scientific article published on 15 September 2016

Targeting coagulation factor XII as a novel therapeutic option in brain trauma

scientific article published on 04 April 2016

Targeting coagulation factor XII provides protection from pathological thrombosis in cerebral ischemia without interfering with hemostasis

scientific journal article

Targeting platelets in acute experimental stroke: impact of glycoprotein Ib, VI, and IIb/IIIa blockade on infarct size, functional outcome, and intracranial bleeding

scientific article

Tenascin-C preserves microglia surveillance and restricts leukocyte and, more specifically, T cell infiltration of the ischemic brain

scientific article published on 22 October 2020

The 1027th target candidate in stroke: Will NADPH oxidase hold up?

scientific article

The Coagulation Factor XIIa Inhibitor rHA-Infestin-4 Improves Outcome after Cerebral Ischemia/Reperfusion Injury in Rats

scientific article published on 27 January 2016

The Coagulation Factors Fibrinogen, Thrombin, and Factor XII in Inflammatory Disorders-A Systematic Review

scientific article published on 26 July 2018

The Formation of Microthrombi in Parenchymal Microvessels after Traumatic Brain Injury Is Independent of Coagulation Factor XI.

scientific article published on 17 February 2016

The Inflammatory Role of Platelets: Translational Insights from Experimental Studies of Autoimmune Disorders

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The NKG2D-IL-15 signaling pathway contributes to T-cell mediated pathology in inflammatory myopathies

scientific article published on 4 December 2015

The Role of Peripheral Myelin Protein 2 in Remyelination

scientific article published on 26 April 2017

The anterior eye chamber: entry of the natural excretion pathway of gadolinium contrast agents?

scientific article published on 16 March 2020

The brain antigen-specific B cell response correlates with glatiramer acetate responsiveness in relapsing-remitting multiple sclerosis patients

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The calcium sensor STIM1 is an essential mediator of arterial thrombosis and ischemic brain infarction

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The contribution of TWIK-related acid-sensitive K+-containing channels to the function of dorsal lateral geniculate thalamocortical relay neurons.

scientific article published on 19 January 2006

The neuroprotective impact of the leak potassium channel TASK1 on stroke development in mice

scientific article

The phosphodiesterase-4 inhibitor rolipram protects from ischemic stroke in mice by reducing blood-brain-barrier damage, inflammation and thrombosis.

scientific article

The potassium channels TASK2 and TREK1 regulate functional differentiation of murine skeletal muscle cells.

scientific article published on 3 August 2016

The quality of cortical network function recovery depends on localization and degree of axonal demyelination

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The trials and errors in MS therapy

scientific article published on September 2008

The two-pore domain potassium channel KCNK5 deteriorates outcome in ischemic neurodegeneration.

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Therapeutic approaches to multiple sclerosis: an update on failed, interrupted, or inconclusive trials of immunomodulatory treatment strategies

scientific article published on August 2010

Therapeutic approaches to multiple sclerosis: an update on failed, interrupted, or inconclusive trials of neuroprotective and alternative treatment strategies

scientific article published on October 2010

Thrombin-activatable fibrinolysis inhibitor (TAFI) deficient mice are susceptible to intracerebral thrombosis and ischemic stroke

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Thromboinflammation in Stroke Brain Damage

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Thrombomodulin, a Master Switch Controlling Poststroke Microvascular Remodeling and Angiogenesis

scientific article published on 24 November 2020

Topological remodeling of cortical perineuronal nets in focal cerebral ischemia and mild hypoperfusion

scientific article published on 06 August 2018

Transient receptor potential melastatin subfamily member 2 cation channel regulates detrimental immune cell invasion in ischemic stroke

scientific article published on 18 September 2014

Transient widespread blood-brain barrier alterations after cerebral photothrombosis as revealed by gadofluorine M-enhanced magnetic resonance imaging

scientific article published on 29 October 2008

Trapped in the epineurium: early entry into the endoneurium is restricted to neuritogenic T cells in experimental autoimmune neuritis

scientific article published on 01 August 2018

Tumour Treating Fields (TTFields) in combination with lomustine and temozolomide in patients with newly diagnosed glioblastoma

scientific article published on 11 December 2019

Two pore domain potassium channels in cerebral ischemia: a focus on K2P9.1 (TASK3, KCNK9).

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VAS2870 is a pan-NADPH oxidase inhibitor

scientific article published on 09 August 2012

Validity and Reliability of Neurological Scores in Mice Exposed to Middle Cerebral Artery Occlusion

scientific article published on 15 August 2019

Visualization of clot composition in ischemic stroke: do we get what we see?

scientific article published on 10 March 2011

Vitiligo after alemtuzumab treatment: Secondary autoimmunity is not all about B cells

scientific article published on 07 November 2018

Von Willebrand factor regulation in patients with acute and chronic cerebrovascular disease: a pilot, case-control study.

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Wallerian degeneration after crush or chronic constriction injury of rodent sciatic nerve is associated with a depletion of endoneurial interleukin-10 protein

scientific article published in July 2004

Why a positive genetic test for myotonic dystrophy type I does not always imply the right diagnosis

scientific article published on December 2006

["Time is brain" in relapsing remitting multiple sclerosis. Current treatment concepts in immunotherapy].

scientific article published in December 2015

[Acute ischemic stroke. New approaches to antithrombotic treatment]

scientific article published on 01 April 2012

[Development of a German telephone version of the IQCODE (The Informant Questionnaire on Cognitive Decline in the Elderly) within a cohort of relatives of ischemic stroke patients]

scientific article published on 10 June 2020

[Experimental therapy approaches for ischemic stroke]

scientific article published on 01 October 2012

[Multiple sclerosis -- a channelopathy? Targeting ion channels and transporters in inflammatory neurodegeneration]

scientific article published on 01 April 2009

[Multiple sclerosis in Germany: updated analysis of the German MS Registry 2014-2018]

scientific article published on 27 July 2020

[Multiple sclerosis in Germany: updated analysis of the German MS Registry 2014-2018]

scientific article published on 01 July 2020

[Pregabalin and gabapentin in multiple sclerosis: clinical experiences and therapeutic implications]

scientific article published on 01 October 2011

[Spinal Muscular Atrophy - expert recommendations for the use of nusinersen in adult patients]

scientific article published on 17 December 2019

[Treatment evaluation in patients with 5q-associated spinal muscular atrophy : Real-world experience]

scientific article published on 01 April 2019

[Update on antithrombotic secondary prevention of ischemic stroke]

scientific article published on 01 October 2019

[Update on pathophysiologic and immunotherapeutic approaches for the treatment of multiple sclerosis]

scientific article published on 01 August 2007

in Vivo Monitoring of Macrophage Infiltration in Experimental Ischemic Brain Lesions by Magnetic Resonance Imaging ⬇️

scientific article published on November 1, 2003

von Willebrand factor: an emerging target in stroke therapy.

scientific article

α(2)-adrenoceptors do not mediate neuroprotection in acute ischemic stroke in mice

scientific article published on 27 July 2011

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