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List of works by David A. Agard

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MotionCor2: anisotropic correction of beam-induced motion for improved cryo-electron microscopy

scientific article published on 27 February 2017
Electron counting and beam-induced motion correction enable near-atomic-resolution single-particle cryo-EM

scientific article published on May 5, 2013
Three-dimensional resolution doubling in wide-field fluorescence microscopy by structured illumination.

scientific article
Subdiffraction multicolor imaging of the nuclear periphery with 3D structured illumination microscopy

scientific article
A SARS-CoV-2 protein interaction map reveals targets for drug repurposing

scientific article published on 30 April 2020
A SARS-CoV-2-Human Protein-Protein Interaction Map Reveals Drug Targets and Potential Drug-Repurposing

journal article from 'bioRxiv' published in 2020
Liquid droplet formation by HP1α suggests a role for phase separation in heterochromatin.

scientific article published on 21 June 2017
Microtubule nucleation by γ-tubulin complexes

scientific article published on October 12, 2011
Structural studies of the scrapie prion protein by electron crystallography

scientific article
Structural Analysis of E. coli hsp90 reveals dramatic nucleotide-dependent conformational rearrangements

scientific article
Identification of new, well-populated amino-acid sidechain rotamers involving hydroxyl-hydrogen atoms and sulfhydryl-hydrogen atoms

scientific article (publication date: 14 November 2008)
UCSF tomography: an integrated software suite for real-time electron microscopic tomographic data collection, alignment, and reconstruction

scientific article published on 23 June 2006
Fast multicolor 3D imaging using aberration-corrected multifocus microscopy

scientific article
Glucocorticoid receptor function regulated by coordinated action of the Hsp90 and Hsp70 chaperone cycles

scientific article
Conformational dynamics of the molecular chaperone Hsp90

scientific article published on 18 March 2011
Fully automated, sequential tilt-series acquisition with Leginon

scientific article
Species-dependent ensembles of conserved conformational states define the Hsp90 chaperone ATPase cycle

scientific article published on December 2008
Microtubule nucleating gamma-TuSC assembles structures with 13-fold microtubule-like symmetry

scientific article
Intramolecular signaling pathways revealed by modeling anisotropic thermal diffusion

scientific article published in August 2005
Multiple conformations of E. coli Hsp90 in solution: insights into the conformational dynamics of Hsp90.

scientific article published on May 2008
Atomic structure of Hsp90-Cdc37-Cdk4 reveals that Hsp90 traps and stabilizes an unfolded kinase

scientific article
The lattice as allosteric effector: Structural studies of   - and  -tubulin clarify the role of GTP in microtubule assembly

scientific article
The crystal structure of the carboxy-terminal dimerization domain of htpG, the Escherichia coli Hsp90, reveals a potential substrate binding site

scientific article
Integration of small-angle X-ray scattering data into structural modeling of proteins and their assemblies

scientific article
Fast live simultaneous multiwavelength four-dimensional optical microscopy

scientific article
Insights into microtubule nucleation from the crystal structure of human gamma-tubulin

scientific article
Structural characterization of a subtype-selective ligand reveals a novel mode of estrogen receptor antagonism

scientific article
Sas-4 provides a scaffold for cytoplasmic complexes and tethers them in a centrosome

scientific article (publication date: 21 June 2011)
Client-Loading Conformation of the Hsp90 Molecular Chaperone Revealed in the Cryo-EM Structure of the Human Hsp90:Hop Complex

scientific article published on June 24, 2011
Substrate Binding Drives Large-Scale Conformational Changes in the Hsp90 Molecular Chaperone

scientific article published on April 8, 2011
Energetic landscape of alpha-lytic protease optimizes longevity through kinetic stability

scientific article published in January 2002
Amorphous no more: subdiffraction view of the pericentriolar material architecture

scientific article published on November 19, 2013
Three-dimensional structure of basal body triplet revealed by electron cryo-tomography

scientific article published on December 13, 2011
An improved strategy for automated electron microscopic tomography

scientific article
Intra- and intermonomer interactions are required to synergistically facilitate ATP hydrolysis in Hsp90.

scientific article
Uncovering a region of heat shock protein 90 important for client binding in E. coli and chaperone function in yeast.

scientific article published on 20 December 2012
I5S: wide-field light microscopy with 100-nm-scale resolution in three dimensions

scientific article
Structural Asymmetry in the Closed State of Mitochondrial Hsp90 (TRAP1) Supports a Two-Step ATP Hydrolysis Mechanism

scientific article
The cancer cell map initiative: defining the hallmark networks of cancer

scientific article published on May 2015
Asynchronous data acquisition and on-the-fly analysis of dose fractionated cryoEM images by UCSFImage

scientific article
Ring closure activates yeast γTuRC for species-specific microtubule nucleation

scientific article
Suite of three protein crystallography beamlines with single superconducting bend magnet as the source

scientific article published on 22 October 2004
The structure of the gamma-tubulin small complex: implications of its architecture and flexibility for microtubule nucleation

scientific article
The structure and assembly dynamics of plasmid actin AlfA imply a novel mechanism of DNA segregation

scientific article
Crystal structure of γ-tubulin complex protein GCP4 provides insight into microtubule nucleation

scientific article published on July 3, 2011
A molecular pore spans the double membrane of the coronavirus replication organelle

scientific article published on 06 August 2020
A Phage Tubulin Assembles Dynamic Filaments by an Atypical Mechanism to Center Viral DNA within the Host Cell

scientific article
A method for integrative structure determination of protein-protein complexes

scientific article
Assembly of a nucleus-like structure during viral replication in bacteria.

scientific article
Mechanistic studies of Sansalvamide A-amide: an allosteric modulator of Hsp90.

scientific article published on January 2010

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