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List of works by Thomas G Beach

3‐hydroxykynurenine and other Parkinson's disease biomarkers discovered by metabolomic analysis ⬇️

scientific article published on July 19, 2013

A Cross-Sectional Analysis of Late-Life Cardiovascular Factors and Their Relation to Clinically Defined Neurodegenerative Diseases

scientific article published on 11 January 2016

A Quantitative Analysis of Brain Soluble Tau and the Tau Secretion Factor

scientific article published on 9 January 2017

A Review of Biomarkers for Neurodegenerative Disease: Will They Swing Us Across the Valley?

scientific article

A high-density whole-genome association study reveals that APOE is the major susceptibility gene for sporadic late-onset Alzheimer's disease

scientific article

APP/Aβ structural diversity and Alzheimer's disease pathogenesis

scientific article

Abnormal phosphorylation of Ser409/410 of TDP-43 in FTLD-U and ALS.

scientific article published on 24 July 2008

Accuracy of the clinical diagnosis of Alzheimer disease at National Institute on Aging Alzheimer Disease Centers, 2005-2010.

scientific article

Aging-related tau astrogliopathy (ARTAG): harmonized evaluation strategy

scientific article published on 10 December 2015

Alpha-Synuclein Pathology and Axonal Degeneration of the Peripheral Motor Nerves Innervating Pharyngeal Muscles in Parkinson Disease ⬇️

scientific article published on February 1, 2013

Alpha-Synuclein Pathology in Sensory Nerve Terminals of the Upper Aerodigestive Tract of Parkinson's Disease Patients

scientific article published on 4 June 2015

Alpha1-chimaerin, a Rac1 GTPase-activating protein, is expressed at reduced mRNA levels in the brain of Alzheimer's disease patients

scientific article

Alterations in immunological and neurological gene expression patterns in Alzheimer's disease tissues

scientific article published on November 2006

Altered APP processing in PDAPP (Val717 --> Phe) transgenic mice yields extended-length Abeta peptides

scientific article published in October 2005

Altered Expression Patterns of Inflammation-Associated and Trophic Molecules in Substantia Nigra and Striatum Brain Samples from Parkinson's Disease, Incidental Lewy Body Disease and Normal Control Cases

scientific article

Altered Pharyngeal Muscles in Parkinson Disease ⬇️

scientific article published on June 1, 2012

Altered neuronal gene expression in brain regions differentially affected by Alzheimer's disease: a reference data set.

scientific article

Alzheimer Disease: Scientific Breakthroughs and Translational Challenges

scientific article published on June 2017

Alzheimer disease periventricular white matter lesions exhibit specific proteomic profile alterations ⬇️

scientific article published on December 8, 2012

Alzheimer's Disease and Non-Demented High Pathology Control Nonagenarians: Comparing and Contrasting the Biochemistry of Cognitively Successful Aging ⬇️

scientific article published on November 7, 2011

Alzheimer's Disease and the “Valley of Death”: Not Enough Guidance from Human Brain Tissue? ⬇️

scientific article published on January 1, 2013

Alzheimer's disease a century later.

scientific article published on November 2006

Alzheimer's disease is associated with altered expression of genes involved in immune response and mitochondrial processes in astrocytes

scientific article

Alzheimer's disease is associated with reduced expression of energy metabolism genes in posterior cingulate neurons

scientific article

Amyloid beta peptide load is correlated with increased beta-secretase activity in sporadic Alzheimer's disease patients

scientific article

Amyloid beta peptides in human plasma and tissues and their significance for Alzheimer's disease

scientific article published on January 2009

Amyloid load in nondemented brains correlates with APOE e4.

scientific article

Amyloid-beta peptide remnants in AN-1792-immunized Alzheimer's disease patients: a biochemical analysis

scientific article

An association with great implications: vascular pathology and Alzheimer disease

scientific article published in January 2006

Analysis of C9orf72 repeat expansions in a large international cohort of dementia with Lewy bodies.

scientific article

Analysis of shared heritability in common disorders of the brain

scientific article published on 21 June 2018

Antemortem-Postmortem Correlation of Florbetapir (18F) PET Amyloid Imaging with Quantitative Biochemical Measures of Aβ42 but not Aβ40.

scientific article published in January 2018

Are Clinical Certainty Ratings Helpful in the Diagnosis of Parkinson's Disease?

scholarly article by Harsh V Gupta et al published 22 February 2018 in Movement disorders clinical practice

Are there differences in cerebral white matter lesion burdens between Parkinson's disease patients with or without dementia?

scientific article

Arizona Study of Aging and Neurodegenerative Disorders and Brain and Body Donation Program

scientific article

Assessing medication role on neuropathological findings in Parkinson's disease

scientific article published on 16 February 2016

Association Between Pathology and Electroencephalographic Activity in Parkinson's Disease

scientific article published in February 2017

Association between repeat sizes and clinical and pathological characteristics in carriers of C9ORF72 repeat expansions (Xpansize-72): a cross-sectional cohort study

scientific article published on 05 September 2013

Association of CD33 polymorphism rs3865444 with Alzheimer's disease pathology and CD33 expression in human cerebral cortex

scientific article

Association of pituitary adenylate cyclase-activating polypeptide with cognitive decline in mild cognitive impairment due to Alzheimer disease

scientific article published in March 2015

Ataxin-2 as potential disease modifier in C9ORF72 expansion carriers

scientific article published on 2 May 2014

Atherosclerosis of cerebral arteries in Alzheimer disease

scientific article published on 16 September 2004

Atherosclerosis, vascular amyloidosis and brain hypoperfusion in the pathogenesis of sporadic Alzheimer's disease

scientific article published in July 2004

Autonomic complaints in patients with restless legs syndrome

scientific article

Autonomic function, as self-reported on the SCOPA-autonomic questionnaire, is normal in essential tremor but not in Parkinson's disease ⬇️

scientific article published on July 6, 2012

BACE1 levels by APOE genotype in non-demented and Alzheimer's post-mortem brains

scientific article

Bapineuzumab Alters Aβ Composition: Implications for the Amyloid Cascade Hypothesis and Anti-Amyloid Immunotherapy ⬇️

scientific article published on March 21, 2013

Bid signal pathway components are identified in the temporal cortex with Parkinson disease ⬇️

scientific article published on September 26, 2012

Biochemical Increase in Phosphorylated Alpha‐Synuclein Precedes Histopathology of Lewy‐Type Synucleinopathies ⬇️

scientific article published on April 12, 2012

Biochemical and Morphological Characterization of the AβPP/PS/Tau Triple Transgenic Mouse Model and Its Relevance to Sporadic Alzheimer's Disease ⬇️

scientific article published on January 1, 2011

Biochemical assessment of precuneus and posterior cingulate gyrus in the context of brain aging and Alzheimer's disease

scientific article

Brain biochemistry in autopsied patients with essential tremor

scientific article published on 28 October 2011

Brain gene expression patterns differentiate mild cognitive impairment from normal aged and Alzheimer's disease

scientific article

C9ORF72 repeat expansions in cases with previously identified pathogenic mutations

scientific article published on 11 September 2013

Calpain-mediated tau fragmentation is altered in Alzheimer's disease progression

scientific article published in Scientific Reports

Cerebral PET with florbetapir compared with neuropathology at autopsy for detection of neuritic amyloid-β plaques: a prospective cohort study ⬇️

scientific article published on June 28, 2012

Cerebral blood flow in Alzheimer's disease

scientific article

Cerebrospinal fluid biomarkers of neuropathologically diagnosed Parkinson’s disease subjects ⬇️

scientific article published on September 1, 2012

Changes in CD200 and intercellular adhesion molecule-1 (ICAM-1) levels in brains of Lewy body disorder cases are associated with amounts of Alzheimer's pathology not α-synuclein pathology

scientific article published on 16 March 2017

Changes in properties of serine 129 phosphorylated α-synuclein with progression of Lewy-type histopathology in human brains

scientific article

Characteristics of patients misdiagnosed with Alzheimer's disease and their medication use: an analysis of the NACC-UDS database

scientific article

Characterization of RNA isolated from eighteen different human tissues: results from a rapid human autopsy program

scientific article published on 16 April 2016

Characterizing Apolipoprotein E ε4 Carriers and Noncarriers With the Clinical Diagnosis of Mild to Moderate Alzheimer Dementia and Minimal β-Amyloid Peptide Plaques

scientific article published on 24 August 2015

Chemical and neuropathological analyses of an Alzheimer's disease patient treated with solanezumab

scientific article

Chemical characterization of pro-inflammatory amyloid-beta peptides in human atherosclerotic lesions and platelets ⬇️

scientific article published on July 20, 2011

Cholesterol retention in Alzheimer's brain is responsible for high beta- and gamma-secretase activities and Abeta production

scientific article

Circle of Willis Atherosclerosis Is a Risk Factor for Sporadic Alzheimer’s Disease ⬇️

scientific article published on September 25, 2003

Circle of Willis atherosclerosis: association with Alzheimer's disease, neuritic plaques and neurofibrillary tangles

scientific article published on 20 September 2006

Clinical Features of Patients with Concomitant Parkinson's Disease and Progressive Supranuclear Palsy Pathology

scientific article published on 29 October 2014

Clinicopathological outcomes of prospectively followed normal elderly brain bank volunteers

scientific article

Clonal Evolution of a Case of Treatment Refractory Maxillary Sinus Carcinoma ⬇️

scientific article published on September 28, 2012

Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions

scientific article

Common variants at MS4A4/MS4A6E, CD2AP, CD33 and EPHA1 are associated with late-onset Alzheimer's disease

scientific article

Comparative proteomics of cerebrospinal fluid in neuropathologically-confirmed Alzheimer's disease and non-demented elderly subjects

scientific article published in March 2006

Comparison of neuropathology in Parkinson's disease subjects with and without deep brain stimulation

scientific article published on 2 December 2016

Comprehensive characterization and optimization of anti-LRRK2 (leucine-rich repeat kinase 2) monoclonal antibodies

scientific article published on July 2013

Concomitant pathologies among a spectrum of parkinsonian disorders

scientific article (publication date: May 2014)

Correlation of Alzheimer disease neuropathologic changes with cognitive status: a review of the literature

scientific article published on May 2012

Correlation of Amyloid PET Ligand Florbetapir F 18 Binding With Aβ Aggregation and Neuritic Plaque Deposition in Postmortem Brain Tissue ⬇️

scientific article published on January 1, 2012

Correlation of clinical features with argyrophilic grains at autopsy

scientific article published on July 2009

Cortical and leptomeningeal cerebrovascular amyloid and white matter pathology in Alzheimer's disease

scientific article

Cortical phosphorylated α-Synuclein levels correlate with brain wave spectra in Parkinson's disease

scientific article published on 08 April 2016

Critical Role of Truncated α‐Synuclein and Aggregates in Parkinson's Disease and Incidental Lewy Body Disease ⬇️

scientific article published on May 23, 2012

Cytokines and Cytokine Receptors Involved in the Pathogenesis of Alzheimer's Disease

scientific article published on 4 August 2016

Deep undepleted human serum proteome profiling toward biomarker discovery for Alzheimer's disease

scholarly article by Kaushik Kumar Dey et al published 2019 in Clinical Proteomics

Deficiency of the Mre11 DNA repair complex in Alzheimer's disease brains

scientific article published in September 2004

Degeneration of human photosensitive retinal ganglion cells may explain sleep and circadian rhythms disorders in Parkinson's disease

scholarly article by Isabel Ortuño-Lizarán et al published 10 September 2018 in Acta neuropathologica communications

Detection of Striatal Amyloid Plaques with [18F]flutemetamol: Validation with Postmortem Histopathology

scientific article published on 31 March 2016

Diagnosis and management of dementia with Lewy bodies: Fourth consensus report of the DLB Consortium

scientific article

Disassembled DJ-1 high molecular weight complex in cortex mitochondria from Parkinson's disease patients

scientific article published on 15 July 2009

Disease duration and the integrity of the nigrostriatal system in Parkinson's disease

scientific article published on August 2013

Dissembled DJ-1 high molecular weight complex in cortex mitochondria from Parkinson's disease patients

scientific article published on 4 June 2009

Do cholinergic therapies have disease-modifying effects in Alzheimer's disease?

scientific article published on April 2006

Does Parkinson's disease start in the gut?

scientific article published on 16 October 2017

Dysregulation of protein phosphatase 2A in parkinson disease and dementia with lewy bodies

scientific article published on 07 September 2016

Effects of multiple genetic loci on age at onset in late-onset Alzheimer disease: a genome-wide association study

scientific article

Elevated beta-secretase expression and enzymatic activity detected in sporadic Alzheimer disease

scientific article

Erratum to: Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue

scientific article published on 26 September 2016

Essential Tremor in the Elderly and Risk for Dementia

scientific article published on 9 April 2014

Essential tremor and Parkinson's disease: Lack of a link ⬇️

scientific article published on January 31, 2011

Essential tremor is not associated with cerebellar Purkinje cell loss

scientific article published on 15 February 2014

Estimation of amyloid distribution by [F]flutemetamol PET predicts the neuropathological phase of amyloid β-protein deposition

Evaluation of Parkinson disease risk variants as expression-QTLs

scientific article

Evaluation of alpha-synuclein immunohistochemical methods for the detection of Lewy-type synucleinopathy in gastrointestinal biopsies

scientific article published on 4 April 2016

Evaluation of alpha-synuclein immunohistochemical methods used by invited experts

scientific article

Evidence for a role of the rare p.A152T variant in MAPT in increasing the risk for FTD-spectrum and Alzheimer's diseases

scientific article

Evidence for an association between KIBRA and late-onset Alzheimer's disease

scientific article

Expression Profiles of Cytokines in the Brains of Alzheimer's Disease (AD) Patients Compared to the Brains of Non-Demented Patients with and without Increasing AD Pathology ⬇️

scientific article published on January 1, 2011

Expression and localization of lactotransferrin messenger RNA in the cortex of Alzheimer's disease

scientific article published on 04 February 2009

Expression and localization of mitochondrial ferritin mRNA in Alzheimer's disease cerebral cortex

scientific article

Faster Cognitive Decline in Dementia due to Alzheimer Disease with Clinically Undiagnosed Lewy Body Disease

Feasibility Study: Comparison of Frontal Cortex Needle Core Versus Open Biopsy for Detection of Characteristic Proteinopathies of Neurodegenerative Diseases

scientific article

Feasibility and Safety of Multicenter Tissue and Biofluid Sampling for α-Synuclein in Parkinson's Disease: The Systemic Synuclein Sampling Study (S4)

scholarly article by Lana M Chahine et al published 2018 in Journal of Parkinson's disease

Florbetaben PET imaging to detect amyloid beta plaques in Alzheimer's disease: phase 3 study

scientific article published on 27 March 2015

Frequency of Alzheimer's disease pathology at autopsy in patients with clinical normal pressure hydrocephalus ⬇️

scientific article published on July 1, 2011

GAB2 alleles modify Alzheimer's risk in APOE epsilon4 carriers

scientific article

Gender Differences in Alzheimer Disease: Brain Atrophy, Histopathology Burden, and Cognition

scientific article published on 12 June 2016

Gene expression correlates of neurofibrillary tangles in Alzheimer's disease

scientific article

Gene expression profiles in Parkinson disease prefrontal cortex implicate FOXO1 and genes under its transcriptional regulation

scientific article

Gene expression profiles in anatomically and functionally distinct regions of the normal aged human brain

scientific article

Genetic analysis of α-synuclein 3' untranslated region and its corresponding microRNAs in relation to Parkinson's disease compared to dementia with Lewy bodies

scientific article published on 18 April 2017

Genetic and clinical features of progranulin-associated frontotemporal lobar degeneration

scientific article

Genetic modifiers in carriers of repeat expansions in the C9ORF72 gene

scientific article

Graph theory network function in Parkinson's disease assessed with electroencephalography

scientific article published on 4 March 2016

Heterogeneous neuropathological findings in Parkinson’s disease with mild cognitive impairment ⬇️

scientific article published on September 14, 2010

Hippocampal sclerosis dementia with tauopathy.

scientific article

Histopathological and molecular heterogeneity among individuals with dementia associated with Presenilin mutations

scientific article

Hypermethylation of Synphilin-1, Alpha-Synuclein-Interacting Protein (SNCAIP) Gene in the Cerebral Cortex of Patients with Sporadic Parkinson's Disease

scientific article published on 27 June 2017

Identification of the genetic basis for complex disorders by use of pooling-based genomewide single-nucleotide-polymorphism association studies

scientific article published on 6 December 2006

Immunohistochemical Method and Histopathology Judging for the Systemic Synuclein Sampling Study (S4)

Impaired hepatic amyloid-beta degradation in Alzheimer's disease

scientific article published in PLoS ONE

Importance of low diagnostic Accuracy for early Parkinson's disease

scientific article published on 04 October 2018

Improved diagnosis of Parkinson's disease from a detailed olfactory phenotype

scientific article published on 8 September 2017

In vitro high affinity alpha-synuclein binding sites for the amyloid imaging agent PIB are not matched by binding to Lewy bodies in postmortem human brain

scientific article published on 21 January 2008

In vitro-differentiated neural cell cultures progress towards donor-identical brain tissue ⬇️

scientific article published on May 10, 2013

Incidental Lewy body disease: Electrophysiological findings suggesting pre-clinical Lewy body disorders ⬇️

scientific article published on May 26, 2011

Incidental Lewy body disease: clinical comparison to a control cohort

scientific article

Increased A beta peptides and reduced cholesterol and myelin proteins characterize white matter degeneration in Alzheimer's disease

scientific article published on September 2002

Increased Alzheimer's disease neuropathology is associated with type 2 diabetes and ApoE ε.4 carrier status

scientific article

Increased CSF biomarkers of angiogenesis in Parkinson disease

scientific article published on 28 October 2015

Increased expression of the urokinase plasminogen-activator receptor in amyloid beta peptide-treated human brain microglia and in AD brains

scientific article published in February 2002

Induction of pluripotent stem cells from autopsy donor-derived somatic cells ⬇️

scientific article published on August 4, 2011

Infiltration of T lymphocytes and expression of icam-1 in the hippocampus of patients with hippocampal sclerosis

scientific article

Integrative analyses of proteomics and RNA transcriptomics implicate mitochondrial processes, protein folding pathways and GWAS loci in Parkinson disease

scientific article published on 21 January 2016

Interaction of the amyloid imaging tracer FDDNP with hallmark Alzheimer's disease pathologies

scientific article

Interpreting Gene Expression Effects of Disease-Associated Variants: A Lesson from SNCA rs356168.

scientific article published on 20 September 2017

Intracranial atherosclerosis as a contributing factor to Alzheimer's disease dementia ⬇️

scientific article published on March 9, 2011

Investigating the genetic architecture of dementia with Lewy bodies: a two-stage genome-wide association study

scientific article published on 16 December 2017

JUMPg: An Integrative Proteogenomics Pipeline Identifying Unannotated Proteins in Human Brain and Cancer Cells

scientific article published on 26 May 2016

Lack of Widespread BBB Disruption in Alzheimer's Disease Models: Focus on Therapeutic Antibodies

scientific article published in October 2015

Laser-captured microglia in the Alzheimer's and Parkinson's brain reveal unique regional expression profiles and suggest a potential role for hepatitis B in the Alzheimer's brain.

scientific article published in November 2017

Lewy bodies are incidental in essential tremor

scientific article published on 3 March 2016

Lewy bodies in essential tremor are no different than in controls

scientific article published on 24 November 2015

Low clinical diagnostic accuracy of early vs advanced Parkinson disease: clinicopathologic study

scientific article

Marked microglial reaction in normal aging human substantia nigra: correlation with extraneuronal neuromelanin pigment deposits

scientific article

Measurement of Altered AβPP Isoform Expression in Frontal Cortex of Patients with Alzheimer's Disease by Absolute Quantification Real-Time PCR ⬇️

scientific article published on January 1, 2012

MicroRNA-101 Modulates Autophagy and Oligodendroglial Alpha-Synuclein Accumulation in Multiple System Atrophy

scientific article published on 17 October 2017

Microglia activation and anti-inflammatory regulation in Alzheimer's disease

scientific article

Mitochondrial DNA Rearrangement Spectrum in Brain Tissue of Alzheimer's Disease: Analysis of 13 Cases

scientific article

Molecular Differences and Similarities Between Alzheimer's Disease and the 5XFAD Transgenic Mouse Model of Amyloidosis

scientific article

Morphological and pathological evolution of the brain microcirculation in aging and Alzheimer's disease

scientific article

Motor impairment in normal aging, clinically possible Parkinson's disease, and clinically probable Parkinson's disease: longitudinal evaluation of a cohort of prospective brain donors

scientific article published in December 2002

Multi-organ distribution of phosphorylated alpha-synuclein histopathology in subjects with Lewy body disorders

scientific article

Multicenter Assessment of Immunohistochemical Methods for Pathological Alpha-Synuclein in Sigmoid Colon of Autopsied Parkinson's Disease and Control Subjects

scientific article published on 31 August 2016

Multiplex immunoassay characterization and species comparison of inflammation in acute and non-acute ischemic infarcts in human and mouse brain tissue

scientific article published on 06 September 2016

Multisite assessment of NIA-AA guidelines for the neuropathologic evaluation of Alzheimer's disease

scientific article

Muscarinic agonists as preventative therapy for Alzheimer's disease.

scientific article

Mutations in progranulin are a major cause of ubiquitin-positive frontotemporal lobar degeneration

scientific article

Myoclonus in Lewy body disorders.

scientific article published in January 2002

NEUROFIBRILLARY TANGLE PREDOMINANT DEMENTIA: CLINICAL AND PATHOLOGICAL DESCRIPTION IN A CASE SERIES

National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease

scientific article

National Institute on Aging-Alzheimer's Association guidelines for the neuropathologic assessment of Alzheimer's disease: a practical approach

scientific article published on 20 November 2011

Neurochemical profile of dementia pugilistica

scientific article

Neuronal gene expression correlates of Parkinson's disease with dementia

scientific article published on August 2008

Neuronal gene expression in non-demented individuals with intermediate Alzheimer's Disease neuropathology

scientific article

Neuropathologic heterogeneity does not impair florbetapir-positron emission tomography postmortem correlates

scientific article

Neuropathological and biochemical assessments of an Alzheimer's disease patient treated with the γ-secretase inhibitor semagacestat

scientific article

Neuropathological basis of nonmotor manifestations of Parkinson's disease

scientific article published on 31 March 2016

Neuropathological comparisons of amnestic and nonamnestic mild cognitive impairment

scientific article published on 20 August 2015

Neuropathological findings of PSP in the elderly without clinical PSP: Possible incidental PSP? ⬇️

scientific article published on March 21, 2011

Neuropathology and Amyloid-β Spectrum in a Bapineuzumab Immunotherapy Recipient ⬇️

scientific article published on January 1, 2011

Next-generation profiling to identify the molecular etiology of Parkinson dementia

scientific article published on 24 May 2016

Novel late-onset Alzheimer disease loci variants associate with brain gene expression

scientific article

Novel tau fragments in cerebrospinal fluid: relation to tangle pathology and cognitive decline in Alzheimer's disease.

scientific article published on 13 December 2018

Olfactory bulb alpha-synucleinopathy has high specificity and sensitivity for Lewy body disorders

scientific article

Olfactory dysfunction in incidental Lewy body disease and Parkinson's disease

scientific article published on 16 August 2014

PARK10 is a major locus for sporadic neuropathologically confirmed Parkinson disease

scientific article

PART, a distinct tauopathy, different from classical sporadic Alzheimer disease

scientific article

PGC-1α, a potential therapeutic target for early intervention in Parkinson's disease

scientific article

PT581. Multiple accumulation of neurodegenerative disease-related proteins in familial granulin mutation brains.

scientific article published on 27 May 2016

Parkinson Disease Affects Peripheral Sensory Nerves in the Pharynx ⬇️

scientific article published on July 1, 2013

Parkinson disease and incidental Lewy body disease: Just a question of time?

scientific article

Parkinson disease with dementia: comparing patients with and without Alzheimer pathology

scientific article published on July 2009

Parkinson's disease, cortical dysfunction, and alpha-synuclein

scientific article

Parkinson’s disease is not associated with gastrointestinal myenteric ganglion neuron loss ⬇️

scientific article published on September 2, 2012

Pathogenic tau modifications occur in axons before the somatodendritic compartment in mossy fiber and Schaffer collateral pathways

scholarly article by Kyle R Christensen et al published 28 February 2019 in Acta neuropathologica communications

Pathologic and nicotinic receptor binding differences between mild cognitive impairment, Alzheimer disease, and normal aging

scientific article published in December 2006

Pathological α-synuclein distribution in subjects with coincident Alzheimer's and Lewy body pathology

scientific article published on 31 December 2015

Pathology in essential tremor ⬇️

scientific article published on January 1, 2012

Peripheral Synucleinopathy in Early Parkinson's Disease: Submandibular Gland Needle Biopsy Findings

scientific article published on 22 January 2016

Phenotypic variability associated with progranulin haploinsufficiency in patients with the common 1477C-->T (Arg493X) mutation: an international initiative

scientific article published in October 2007

Phosphorylated α-synuclein-immunoreactive retinal neuronal elements in Parkinson's disease subjects

scientific article published on 28 April 2014

Physiologic origins of age-related beta-amyloid deposition

scientific article published on 06 March 2008

Pituitary adenylate cyclase-activating polypeptide is reduced in Alzheimer disease

scientific article

Pituitary adenylate cyclase-activating polypeptide protects against β-amyloid toxicity

scientific article published on 22 March 2014

Plaques and tangles as well as Lewy-type alpha synucleinopathy are associated with formed visual hallucinations

scientific article

Positive florbetapir PET amyloid imaging in a subject with frequent cortical neuritic plaques and frontotemporal lobar degeneration with TDP43-positive inclusions

scientific article

Positron emission tomography and neuropathologic estimates of fibrillar amyloid-β in a patient with Down syndrome and Alzheimer disease

scientific article

Post-mortem histopathology underlying β-amyloid PET imaging following flutemetamol F 18 injection

scientific article published on 12 December 2016

Postmortem interval effect on RNA and gene expression in human brain tissue

scientific article

Pre- and post-synaptic cortical cholinergic deficits are proportional to amyloid plaque presence and density at preclinical stages of Alzheimer's disease

scientific article

Presence of Striatal Amyloid Plaques in Parkinson's Disease Dementia Predicts Concomitant Alzheimer's Disease: Usefulness for Amyloid Imaging ⬇️

scientific article published on January 1, 2012

Presenilin-1 280Glu-->Ala mutation alters C-terminal APP processing yielding longer abeta peptides: implications for Alzheimer's disease

scientific article

Prevalence of Submandibular Gland Synucleinopathy in Parkinson's Disease, Dementia with Lewy Bodies and other Lewy Body Disorders

scientific article

Primary age-related tauopathy (PART): a common pathology associated with human aging

scientific article

Probable RBD is increased in Parkinson’s disease but not in essential tremor or restless legs syndrome ⬇️

scientific article published on April 8, 2011

Probing the striatal dopamine system for a putative neuroprotective effect of deep brain stimulation in Parkinson's disease

scientific article published on 30 January 2018

Profiles of extracellular miRNA in cerebrospinal fluid and serum from patients with Alzheimer's and Parkinson's diseases correlate with disease status and features of pathology

scientific article

Progranulin regulates lysosomal function and biogenesis through acidification of lysosomes

scientific article published on 10 January 2017

Progressive aphasia with Lewy bodies

scientific article published in January 2002

Protein Phosphatase 2A and Its Methylation Modulating Enzymes LCMT-1 and PME-1 Are Dysregulated in Tauopathies of Progressive Supranuclear Palsy and Alzheimer Disease

scientific article

Proteomic analysis of Alzheimer's disease cerebrospinal fluid from neuropathologically diagnosed subjects

scientific article

Proteomics-derived cerebrospinal fluid markers of autopsy-confirmed Alzheimer's disease

scientific article

Quantitative appraisal of ventricular cerebrospinal fluid biomarkers in neuropathologically diagnosed Parkinson's disease cases lacking Alzheimer's disease pathology

scientific article published on 12 March 2013

Quantitative measurement of intact alpha-synuclein proteoforms from post-mortem control and Parkinson's disease brain tissue by intact protein mass spectrometry

scientific article

REM sleep behavior disorder and neuropathology in Parkinson's disease

scientific article published on 12 August 2015

Rare coding variants in PLCG2, ABI3, and TREM2 implicate microglial-mediated innate immunity in Alzheimer's disease

scientific article

Rarity of the Alzheimer disease-protective APP A673T variant in the United States

scientific article

Reduced Posterior Cingulate Mitochondrial Activity in Expired Young Adult Carriers of the APOE ε4 Allele, the Major Late-Onset Alzheimer's Susceptibility Gene ⬇️

scientific article published on January 1, 2010

Reduced clinical and postmortem measures of cardiac pathology in subjects with advanced Alzheimer's Disease ⬇️

scientific article published on January 25, 2011

Refined phosphopeptide enrichment by phosphate additive and the analysis of human brain phosphoproteome

scientific article

SMG1 identified as a regulator of Parkinson's disease-associated alpha-synuclein through siRNA screening

scientific article

Severe hyposmia distinguishes neuropathologically confirmed dementia with Lewy bodies from Alzheimer's disease dementia

scientific article published on 22 April 2020

Simplified conversion method for unified Parkinson's disease rating scale motor examinations

scientific article

Small-amplitude cortical myoclonus in Parkinson's disease: physiology and clinical observations

scientific article published in July 2002

Striatal Amyloid Plaque Density Predicts Braak Neurofibrillary Stage and Clinicopathological Alzheimer's Disease: Implications for Amyloid Imaging ⬇️

scientific article published on January 1, 2012

Subjects harboring presenilin familial Alzheimer's disease mutations exhibit diverse white matter biochemistry alterations

scientific article published on 18 September 2013

Submandibular Gland Biopsy for the Diagnosis of Parkinson Disease ⬇️

scientific article published on February 1, 2013

Submandibular gland needle biopsy for the diagnosis of Parkinson disease

scientific article published on 05 February 2014

Substantia nigra Marinesco bodies are associated with decreased striatal expression of dopaminergic markers

scientific article published in April 2004

Systematic optimization of long gradient chromatography mass spectrometry for deep analysis of brain proteome

scientific article

TDP-43 deposition in prospectively followed, cognitively normal elderly individuals: correlation with argyrophilic grains but not other concomitant pathologies

scientific article published on 20 April 2013

THE HUMAN BRAINOME: HUMAN BRAIN GENOME, TRANSCRIPTOME, AND PROTEOME INTEGRATION

TMEM106B haplotypes have distinct gene expression patterns in aged brain.

scientific article

TMEM106B protects C9ORF72 expansion carriers against frontotemporal dementia

scientific article published on 03 January 2014

TMEM106B regulates progranulin levels and the penetrance of FTLD in GRN mutation carriers.

scientific article

TREM2 Protein Expression Changes Correlate with Alzheimer's Disease Neurodegenerative Pathologies in Post-Mortem Temporal Cortices

scientific article published on 11 November 2014

Tg-SwDI transgenic mice exhibit novel alterations in AbetaPP processing, Abeta degradation, and resilient amyloid angiopathy

scientific article published on 3 July 2008

TgCRND8 amyloid precursor protein transgenic mice exhibit an altered gamma-secretase processing and an aggressive, additive amyloid pathology subject to immunotherapeutic modulation

scientific article

The 4p16.3 Parkinson Disease Risk Locus Is Associated with GAK Expression and Genes Involved with the Synaptic Vesicle Membrane

scientific article

The Distribution of Phosphorylated Tau in Spinal Cords of Alzheimer's Disease and Non-Demented Individuals ⬇️

scientific article published on January 1, 2013

The Impact of Aging on Brain Pituitary Adenylate Cyclase Activating Polypeptide, Pathology and Cognition in Mice and Rhesus Macaques

scientific article

The Presence of Select Tau Species in Human Peripheral Tissues and Their Relation to Alzheimer's Disease

scientific article published in October 2016

The Presence of Select Tau Species in Human Peripheral Tissues and Their Relation to Alzheimer's Disease

scientific article published on 3 February 2016

The Search for a Peripheral Biopsy Indicator of α-Synuclein Pathology for Parkinson Disease

scientific article published on 9 January 2017

The Sun Health Research Institute Brain Donation Program: description and experience, 1987-2007

scientific article published on 18 March 2008

The Systemic Synuclein Sampling Study: toward a biomarker for Parkinson's disease

scientific article published on 29 March 2017

The biochemical aftermath of anti-amyloid immunotherapy ⬇️

scientific article published on October 7, 2010

The human brainome: network analysis identifies HSPA2 as a novel Alzheimer’s disease target

The influence of Apolipoprotein E genotype on regional pathology in Alzheimer's disease

scientific article

The temporal localization of frame-shift ubiquitin-B and amyloid precursor protein, and complement proteins in the brain of non-demented control patients with increasing Alzheimer's disease pathology

scientific article published in September 2003

Theoretical impact of Florbetapir (18F) amyloid imaging on diagnosis of alzheimer dementia and detection of preclinical cortical amyloid

scientific article

Thiorphan-induced neprilysin inhibition raises amyloid beta levels in rabbit cortex and cerebrospinal fluid

scientific article published in October 2003

Transcranial Doppler ultrasound blood flow velocity and pulsatility index as systemic indicators for Alzheimer's disease ⬇️

scientific article published on March 9, 2011

Unified staging system for Lewy body disorders: correlation with nigrostriatal degeneration, cognitive impairment and motor dysfunction

scientific article published on 28 April 2009

Whole genome association analysis shows that ACE is a risk factor for Alzheimer's disease and fails to replicate most candidates from Meta-analysis

scientific article

Whole transcriptome profiling of the human hippocampus suggests an involvement of the KIBRA rs17070145 polymorphism in differential activation of the MAPK signaling pathway

scientific article published on 22 April 2017

[(18)F]flutemetamol amyloid positron emission tomography in preclinical and symptomatic Alzheimer's disease: specific detection of advanced phases of amyloid-β pathology

scientific article published on 30 June 2015

microRNA Profiles in Parkinson's Disease Prefrontal Cortex

scientific article published on March 2016

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